Bentley, M.
Davies, B.
This document is a proposal sent from Covance Laboratory in the United Kingdom in response to an inquiry from Dr. Bruce Davies at the Philip Morris Tobacco Company, who apparently asked Covance about the possibility of performing a scientific investigation "to determine whether the addition of ammonium compounds by cigarettes enhances the avilability of nicotine to the smoker."
The lab sent Dr. Davies this proposal to do the experiment using human subjects. Mark Bentley of Covance proposed that the human subjects would smoke test cigarettes and then have blood samples drawn at various intervals prior to, and after puffing on the test cigarettes. The subjects's blood would then be analyzed to determine the concentration of nicotine in their plasma before and during smoking the cigarettes.
While we don't know if this study was ever done, this correspondence appears to reflect a continued interest by Philip Morris' in finding ways to enhance the delivery of nicotine to the smoker without actually adding more nicotine to their cigarettes.