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Anne Landman's Collection

Subject: Philip Morris Research

Date: 23 Jul 1992
Length: 11 pages
2022850392-2022850402
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bliley_pm 2022850392-2022850402

Abstract

This 1992 Philip Morris (PM) document about the funding of various research projects around the world indicates that there are a number of less-then-obvious reasons why PM funds research projects in various countries. The author of the document is Charles Wall, Vice President and Associate General Counsel for PM. According to the document, PM funded some research projects in part because the scientists performing them had good contacts with government officials and within the research community in that country: "While the research recommended for funding in 1993 through Tassin,Dusser, Molimard, Micheletti, Hirt and Symann is good, another reason for funding them is due to the importance of those researchers in their respective countries. For the most part, they have excellent contacts within the scientific community and the government and, therefore, are of assistance to Philip Morris..."

The document also makes it apparent that PM funded research simply to create a "presence" in a given country that might yield political benefit to the company:

"I view with some concern the research effort in Germany...Much of the research focuses on nicotine...There are a number of projects which could easily be canceled, or not started, that could save us several hundred thousand DM. ...Our scientists feel, however, that it is important to keep the research money in Germany, i.e., continue to support researchers in Germany... [W]hile Paul may not have any problem with the reduction [in funding], my guess is that he will feel that we should attempt to locate worthwhile research projects in Germany, so that we are in a position, in dealing with the German government, to point to ongoing research projects in that country. The relationship between the industry and the German government seems to be a good deal better than the relationship between the industry and the government in this country [the United States]. As I understand it, there are regular consultations between government and industry scientists, as well as constructive discussions regarding smoking-related laws and regulations. The industry in Germany appears to be more influential with the government than the industry in the U.S., and, for that reason, the industry feels it is important to maintain a substantial research presence [in Germany]."

PM also sponsored research in a given country in anticipation of litigation, in hopes of helping sway court decisions in their favor:

"Although I do not believe litigation is imminent in Germany, should it occur, the fact that we are sponsoring research...could be of substantial help in convincing a court that we are fulfilling our duty to conduct research."

Fields

Quotes

Our scientists feel, however, that it is important to keep the research money in Germany, i.e., continue to support researchers in Germany even if we are not supporting them through the Verband. I have asked both Walter Fink and Helmut Reif to talk with Paul Hendrys about a general reduction in the VdC budget, and whether he feels it is necessary to continue to spend the money in Germany. While Paul may not have any problem with the reduction, my guess is that he will feel that we should attempt to locate worthwhile research projects in Germany, so that we are in a position, in dealing with the German government, to point to ongoing research projects in that country. The relationship between the industry and the German government seems to be a good deal better than the relationship between the industry and the government in this country. As I understand it, there are regular consultations between government and industry scientists, as well as constructive discussions regarding smoking-related laws and regulations. The industry in Germany appears to be more influential with the government than the industry in the U.S. and, for that reason, the industry feels it is important to maintain a substantial research presence.

Although I do not believe litigation is imminent in Germany, should it occur, the fact that we are sponsoring research -- whether through the Verband, or individually - could be of substantial help, in convincing a court that we are fulfilling our duty to conduct research. Nor do I think we should downplay the importance of having scientific contacts in as important a country as Germany.

Company
Philip Morris Cos., Inc.
Author
Wall, Charles R. (PM VP & Assoc. Gen. Counsel, c. 1994)
Vice President and Associate General Counsel for Philip Morris 1994-94 (may have been longer; this info was gleaned from documents); formerly worked for Shook, Hardy and Bacon.
Recipient
Bring, Murray H. (PM Attorney, Sr. VP & Counsel, Board of Directors)
Senior Vice President and General Counsel of PM, 1994; former partner of Arnold & Porter in Washington, D.C. Defended PM in the Cipollone case.
Region
Australia
Switzerland
Germany
Netherleands
Belgium
United States
Italy
France
Named Organization
FTR, Fabriques de Tabac Reunies, (PM R&D facility in Neuchatel, Switzerland)
Fabriques de Tabac Reunies, Philip Morris Research and Development facility in Nuechatel, Switzerland. Many of the documents generated by this facility are in German or French language.
Philip Morris Incorporated (Philip Morris U.S.A.) (a wholly-owned subsidiary of Philip Morris Co., Inc.)
A wholly-owned subsidiary of Philip Morris Co., Inc.
INBIFO, Intitut Fur Biologische Forschung (Philip Morris' secret biological research lab in Europe)
"INBIFO" stands for Institut Fur Biologische Forschung, or Institute for Biological Research. It is located in Germany. Philip Morris acquired Inbifo on June 30, 1971. Its stated mission was "quantitative biological product evaluation" by using "comprehensive toxicological and physiological testing. Major activities are listed as: product evaluation and modifications, product ingredients and ETS-related technical knowledge and smoke components. Inhalation toxicology was a key feature of Inbifo. (Derived from Bates No. 2505235055/5088)
FTR, Fabriques de Tabac Reunies, (PM R&D facility in Neuchatel, Switzerland)
Fabriques de Tabac Reunies, Philip Morris Research and Development facility in Nuechatel, Switzerland. Many of the documents generated by this facility are in German or French language.
Case Western
Meyer Friedman Institute
Tassin, Dusser, Molimard, Micheletti, Hirtand Symann
Australian Tobacco Research Council (Functioned much like the CTR in the U.S.)
Kings College
Weetman and Nilsen
*Council for Tobacco Research-- U.S.A. Inc. CTR (Formerly Tobacco Industry Research Committee (TIRC))
Created and funded by the tobacco industry to award grants to study of the link between smoking and disease. Part of a four decade effort to cast doubt on the links between smoking and disease.
Philip Morris Corporate Affairs - EEC
*Scientific Advisory Board (SAB) (Only use SAB with name of specific org.)
Duke Unversity
Medical College of Virginia
Johns Hopkins University School of Medicine
Philip Morris Institute (PM-supported biomeidcal research institute formed c. 1994)
A Philip Morris-created entity that funded research to "contribute in a major way to the advancement of medical science," to "be, and be seen to be pro bono publico," and to "optimize the impact of of Philip Morris products on the quality of life of consumers" and to "convey a strong public relations image." (PM 2023119435/9446, 1994).
Named Person
Andrade, Anthony J. "Tony" (PM Associate General Counsel, Switzerland)
Associate General Counsel for Philip Morris. Worked for Shook, Hardy and Bacon. Vice President, PM Worldwide Regulatory Affairs, 1994. Responsible for management and direction of ETS focused department. Reported to Steven Parrish, Senior VP of PM External Affairs.
Parrish, Steven C. (PM, Sr. VP, General Counsel)
Partner of industry law firm Shook Hardy and Bacon before going to work for PM. Was VP of PM Corporate Scientific Affairs in 1990. Defends PM on television.
Carchman, Richard Allan, Ph.D. (PM Scientific Affairs, Research & Development VP)
Philip Morris Director and worked in Scientific Affairs. Reported to Cathy ellis.
Charles, James L., Ph.D. (PM, R&D VP, Pharmacologist, Industry Expert)
Vice President of Research and a scientist for Philip Morris, Inc. Vice President of Research for Philip Morris, Inc. in 1986 and then again from 1992 to 1993.
Marcovitch, Iancou (VP Science & Tech., PM Europe)
Iancou Marcovitch was a Philip Morris Scientist - Europe & Industry Communications, Vice Director Science and Technology of Philip Morris Europe. (PMI's Introduction to Privilege Log and Glossary of Names, Estate of Burl Butler v. PMI, et al, April 19, 1996)
Martin, Peter (PM Senior Scientist c. 1992)
Peter Martin was an Associate Principal Scientist for Philip Morris Europe. (PMI's Introduction to Privilege Log and Glossary of Names, Estate of Burl Butler v. PMI, et al, April 19, 1996) Dr. Peter Martin worked for Philip Morris Research Center at Box 26583, Richmond, Virginia 23261 in 1975. [Butler 2021648905-13, (P.O.)]
Reif, Helmut E. (PM Europe Science & Tech. Director, 1980s)
Helmut Reif was Director of Science and Technology for FTR. (PMI's Introduction to Privilege Log and Glossary of Names, Estate of Burl Butler v. PMI, et al, April 19, 1996)
Caboche
Schneider
Vincze
Syjaenen
Aho
Gerrod
Cerutti
Haab
Brunner
Battig
Goldsmith, Clifford Henry (B&H (1953), PM Chief of Operations ('65) Pres of PM, Inc. (')
1953 Benson & Hedges. 1965 Philip Morris USA Chief of Operations. 1969-73 President of Philip Morris, Inc. 1978 PM Chief Executive. Served on Tobacco Institute Executive Committee, 1979.
Malherbe
Francis, P.
Eaves, L., Dr.
Houghton, K.
Jim
Richard
Abood, Leo G., Ph.D. (Biochemist, U of Rochester Med. Ctr.)
Outside research on nicotine analogs for PM. University of Rochester. Around 1980.
Guzelian, Philip (Philip Morris scientific consultant)
Philip Guzelian's consultancy with Philip Morris was concurrent with that of Leo Abood and Ragnar Rylander. He made $100,000 per year from PM. (Bliley PM 23838)
Rylander, Ragnar, M.D. (PM contractor, Environmental Hygienist, U of Gothenburg)
Professor of Environmental Hygiene, University of Gothenburg, Sweden. Worked on contract to Philip Morris overseeing biological laboratory work being performed at INBIFO, PM's biological labs in Cologne, Germany. PM paid Rylander $150,000 per year (salary determined from Bliley PM doc 2022850392, from 1992)
Hendrys, P (Managing Director)
1993 Germany
Fink, W.
Klag, M.
Hopkins, J.
Lee, Peter N. (TAC Biostatistician)
Frequently funded by the tobacco industry to criticize and discount published and epidemiological studies that linked between tobacco smoking and health damage.
Warburton, David M. Dr. (Psychopharmacologist, University of Reading, UK)
Director of Human Psychopharmacology group at University of Reading in the United Kingdom, Dr. Warburton published a paper "The Functions of Pleasure" which grouped tobacco with chocolate, coffee and food as substances which "give us pleasure and enhance the quality of our lives." He founded the tobacco-industry funded group ARISE (Associates for Research in Substance Enjoyment, later changed to the "Science of Enjoyment"). ARISE was also funded by breweries, distilleries and a food company.
Papconstantinou, A.
Altmann, Hans (Molecular Biologist and Biochemist)
1989 Seibersdorf, Austria
Williams, R., Dr.
Edelman, Gerald
Operation/Project
Project Beta (free-standing 6 mg. cigarette)
Type
Memorandum
Subject
research activity
industry activity
industry sponsored research

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Page 1: 2022850392
PHILIP MORRIS COMPANIES INC. INTER-OFFICE CORRESPONDENCE FROM: SUBJECT: Murray H. Bring Charles R. Wall Philip Morris Research 120 PARK AVENUE, NEW YORI~ N.Y. 10017.5592 DATE:: July 23, 1992 On May 19, Tony Andrade, Steve Parrish and I met with Richard Carchman, Jim Charles, Ian Marcovitch, Peter Martin and Helmut Reif, senior scientists with Philip Morris. Our discussions focused on the research set forth in the notebook given to you on May 13. We discussed the merits of each research project and funding needs for 1993. In addition, we discussed the research funding requests set forth as Exhibits D, E, F and G, in the notebook. I will discuss the research as it appears in the memorandum in the notebook, pages 2 to 14. I. Primary issue grants formerly with FTR/S&T, now with Steve Parrish. Ian Marcovitch is the Philip Morris liaison with most of these researchers. Ian feels that most of the research should be continued in 1993. Of the scientists listed, Caboche, Schneider and Vincze, will not be funded in 1993. The total for these researchers is 179,100 (CHF). We recommend an increase in funding for Syrjaenen, of 30,200 (CHF). As a result of his assistance to the industry in the Aho case, his funding from the Finnish scientific establishment was stopped. The net savings for those researchers for 1993 will be 148,900 (CHF).
Page 2: 2022850393
TO: Murray H. Bring RE: Philip Morris Research July 23, 1992 Page Two While the research recommended for funding in 1993 through Tassin, Dusser, Molimard, Micheletti, Hirt and Symann is good, another reason for funding them is due to the importance of those researchers in their respective countries, For the most part, they have excellent contacts within the scientific community and the government and, therefore, are of assistance to Philip Morris, in keeping abreast of developments in both arenas. The research sponsored at Kings College, by Professor Gerrod and through Weetman and Nilsen, is ETS research, taken care of in Steve Parrish's budget and, therefore, not the subject of this review. Netherlands (Schticting). The research here amounts to only $16,500 and provides us with a research presence in the Netherlands, which is considered of some value. Switzerland (AFSC). Because FTR is located in Switzerland, everyone feels it is important to continue significant contributions to researchers there. Philip Morris's share of that research funding (200,000 CHF), based on its market share, is quite reasonable. Some of the research is quite good, such
Page 3: 2022850394
TO: Murray H. Bring RE: Philip Morris Research July 23,1992 Page Three as that of Cerutti and Haab. The research of Brunner and B/ittig is subject to some question. In Brunner's case, I question the relevance, and in B/ittig's, I question its importance. Marcovitch believes we should continue our current funding level. I agree, and have asked Marcovitch to be on the alert for other research proposals. IV. Belgium (Fetatab). The research of Malherbe (9,000 CHF) has been canceled, and is not being funded in 1992. Australia (ATRF). Australia presents an interesting problem. Phil Francis has reported that it is becoming increasingly difficult to get good research applications, because of the political environment in Australia. Phil has even raised the question as to whether we should disband the Australian Tobacco Research Council and, hence, our research efforts in Australia. Apparently, the Council operates much like the CTR in the United States; I am reluctant to recommend any decrease in research funding, because some research presence is necessary, and can be beneficial to the Company. Rather, I would like to explore the possibility of locating other researchers, who have worthwhile projects, and fund them. This would mean a slight
Page 4: 2022850395
TO:. Murray H. Bring RE: Philip Morris Research July 23, 1992 Page Four change in the emphasis in Australia, from applications and grants to contracts. I am of the opinion that we should, at least, make an effort to find first-class researchers to fund, in Australia, and recommend that Richard Carchman be asked to try to develop some research ideas for Australia. The amount is not that great, and can still serve a very useful purpose. VI. INBIFO. This is, by far, the largest funding (approximately $14,000,000) supported by the Company, and the breakdown of the research is set forth on page 6. Ken Houghton, Jim Charles and Richard Carchman are of the view that INBIFO is extremely important to the Company's ability to do product evaluation, develop new products, and respond to scientific, regulatory and legal issues, worldwide. Currently, a major product evaluation and development effort is focused on Project Beta, which is the project we recently discussed in Richmond. ]~BIFO is also doing work on environmental tobacco smoke and testing ingredients. Based on my own observations and discussions with Jim, Richard and the scientists at INBIFO, I doubt that the funds allocated to INBIFO can be better spent elsewhere. My sense is that INBIFO provides an important research function for the Company.
Page 5: 2022850396
TO: Murray FL Bring RE: Philip Morris Research July 23, 1992 Page Five In addition, as I previously informed you, Steve Parrish and I have asked Jim and Richard to prepare a protocol and budget for a lifetime ETS inhalation experiment. I am told that such a project, whether done in- house or under contract with an outside laboratory, will cost between two and three million dollars. VII. Philip Morris USA. Philip Morris maintains consultancies with Leo Abood, Philip Guzelian and Ragnar Rylander. It is Jim Charles's view that the relationship with Abood should stop after 1992, which will free up $90,000 for 1993, and that the relationship with Guzelian should stop after 1993, which will free up $100,000 in subsequent years~ Both Jim and Carchman believe that our relationship with Ragnar Rylander has proved beneficial to the Company, and should continue; i.e., $150,000 per year. We are committed to the Case Western funding, as set forth on page 7. We have discussed the Meyer Friedman funding, and we are interested, I believe, in supporting that funding until November 1998, which would cost about $1.3 million per year.
Page 6: 2022850397
TO: Murray H. Bring RE: Philip Morris Research July 23,1992 Page Six The Verband (VdC). I do not know what control we have over the Philip Morris portion of the VdC budget. Our 1992 budgeted research contribution is 34% of 8,656,000 DM, or about $1,800,000. I view with some concern the research effort in Germany. The Research Council operates much like the SAB of the CTR, and supports research based on grant applications. Much of the research focuses on nicotine. As you can tell, the Research Council's budget is approximately 2,500,000 DM, of which our share is $519,880. There is additional research funded by the industry outside of the Research Council, and that amount is budgeted in 1992 at approximately 2,900,000 DM, of which our share is $603,060. It is this latter research that I believe could be reduced without a significant downside to the industry. There are a number of projects which could easily be canceled, or not started, that could save us several hundred thousand DM. Rather than eliminate any specific projects, the best approach is to discuss with Paul Hendrys the possibility of reducing the budget for 1993 by 20%. Our scientists feel, however, that it is important to keep the research money in Germany, i.e., continue to support researchers in Germany even
Page 7: 2022850398
TO: Murray I-L Bring RE: Philip Morris Research July 23, 1992 Page Seven if we are not supporting them through the Verband. I have asked both Walter Fink and Helmut Reif to talk with Paul Hendrys about a general reduction in the VdC budget, and whether he feels it is necessary to continue to spend the money in Germany. While Paul may not have any problem with the reduction, my guess is that he will feel that we should attempt to locate worthwhile research projects in Germany, so that we are in a position, in dealing with the German government, to point to ongoing research projects in that country. The relationship between the industry and the German government seems to be a good deal better than the relationship between the industry and the government in this country. As I understand it, there are regular consultations between government and industry scientists, as well as constructive discussions regarding smoking-related laws and regulations. The industry in Germany appears to be more influential with the government than the industry in the U.S~ and, for that reason, the industry feels it is important to maintain a substantial research presence. Although I do not believe litigation is imminent in Germany, should it occur, the fact that we are sponsoring research -- whether through the Verband, or individually - could be of substantial help, in convincing a
Page 8: 2022850399
TO: Murray H. Bring RE: Philip Morris Research July 23,1992 Page Eight court that we are fulfilling our duty to conduct research. Nor do I think we should downplay the importance of having scientific contacts in as important a country as Germany. Therefore, a reduction in the Verband budget will have little impact on the availability of money for other research programs outside Germany. Philip Morris prize awards. These total 300,000 CHF each year, and are administered through Philip Morris Corporate Affairs - EEC. Marcovitch feels these are important to keep Philip Morris's name and presence known in France, Italy and Germany. I recommend we continue these programs. Xo Other consultants. These all appear to be ETS consultants, and are administered by Steve Parrish and paid through his budget. Research applications, A. Meyer Friedman Institute. This needs further discussion. B. Duke University (Dr. Red Williams). I do not recommend the continuation of this project, but I should note that Dr. Williams apparently has good contacts with Cliff Goldsmith. Williams asked
Page 9: 2022850400
TO: Murray t-L Bring RE: Philip Morris Research July 23, 1992 Page Nine Do Jim Charles whether he should talk to Cliff with regard to the funding of his project. You will note on page 13 that Dr. Williams is requesting $380,000 each year for the next two years, for a total of $760,000. As I said in my memo of April 7 to you and Bill Murray, currently, we do not have any funds in 1992 or 1993 for this project. Medical College of Virginia (Lyndon Eaves). Jim Charles has told Dr. Eaves that we will not be able to fund his research. Johns Hopkins University School of Medicine. Dr. Michael Klag is requesting approximately $51,000 a year for the next two years, to fund what he calls "the precursors" study." See Exhibit E in my report of May 20 to you. Basically, the study is designed to identify psychological, behavioral, genetic, physiologic and social factors associated with the development of hypertension and premature cardiovascular disease. Jet Lincoln was, and remains, fond of this study, and Philip Morris has been a supporter of it, or similar studies~ at Johns Hopkins, for a number of years. Since 1986, we have given the following amounts to Johns Hopkins University: 1986: $199,136 1987: 182,440 1990: 298,777
Page 10: 2022850401
TO: Murray H. Bring RE: Philip Morris Research July 23, 1992 Page Ten While the work is of scientific interest~ I have concerns about its direct applicability to our problems and, therefore, the priority we ought to assign to it. Peter Lee. This amount is approximately $60,000, and the general view is that the information from the autopsies could prove extremely helpful and, therefore, this should be funded. D. Warburton. This will not be funded. Anthony Papconstantinou (Greece). This study will not be funded. Hans Altmann. This study will not be funded. XU. Summary. As you can see, there are some projects which we will not fund in 1993. You can also see, however, that the amount of money saved is relatively insignificant when compared to the research requests. Therefore, the decision must be made as to whether we are going to come up with the necessary money to fund Friedman until 1998, in the amount of $1.3 million per year, and Dr. Williams at Duke University, in the amount of approximately $760,000 for the next two years. If we are going to fund either or both of these projects, we will need a supplemental appropriation, as I discussed in my memos of April 1 and April 7.

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