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Biotech: Discovering new ways to blame the smoker? Letter from Burson Marstellar to PM, 1996

Date: 25 Sep 1996
Length: 2 pages
2060546551-2060546552
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Abstract

In this letter, Michael Johnson, the Director of Media for Philip Morris' PR firm Burson-Marstellar in London, invites PM to team up with an "advanced biotech research organization" in Britain that is involved in the human genome project. Johnson proposes that perhaps through human genome research they could locate a gene that predisposes people to smoking-related diseases. Johnson helpfully suggests that this could both encourage smoking while relinquishing Philip Morris from liability for selling a deadly product: "This work could be interesting to Philip Morris for at least three reasons:

--A simple test might eventually be devised to tell a smoker whether or not he is at risk. This would put the burden of any consequence from smoking on the individual, and would clear the way for the non-susceptible population to smoke with a clear conscience.

--Philip Morris would be seen to be contributing to research into the health effects of smoking...

--Finally, someone will eventually get around to this kind of research. Wouldn't it be better to be leading it?"

Fields

Notes

NOTES: In casting about for something other than tobacco that they could point to as being the culprit causing lung disease in smokers, the tobacco industry has come up with some interesting hypotheses. Their "carotene hypothesis" attempted to blame lung cancer on a high intake of dietary carotene: (http://www.pmdocs.com/getallimg.asp?DOCID=2024258946). Another view, promoted for some time, was the "Constitutional Hypothesis," which claimed that a genetic defect caused some human beings to "have difficulty adapting to the problems of existence." Thus they claimed that smoking was a substitute for people's normal coping mechanisms (http://www.pmdocs.com/getallimg.asp?DOCID=1005136046.) One of the most bizarre theories was the "Reverse Hypothesis," in which Philip Morris scientists tried to find some way to substantiate the claim that lung disease causes smoking. Today's document seems to represent a form of the "self-selection" hypothesis, which proposes that the people with the highest tendency toward getting cancer for some reason also tend to choose to smoke.

Quotes

An advanced biotech research organisation in the UK, Amersham International, is involvedin the genome project--th elong term effort to identify all human genes. Through a friend of mine, I have discovered a possible Amercham project that could have an impact on the tobacco industry. You may be miles ahead of me in this area, but I thought it was important enough to pass along, just in case.

The point of this project would be to help individuals understand their genetic susceptibility to disease related to smoking. Since we all react differently to the effects of smoking, it obviously would be useful for each person to know whether or not he or she carries the genes that make ill effects likely.

This work could be interesting to Philip Morris for at least three reasons:

--A simple test might eventually be devised to tell a smoker whether or not he is at risk. This would put the burden of any consequence from smoking on the individual, and would clear the way for the non-susceptible population to smoke with a clear conscience.

--Philip Morris would be seen to be contributing to research into the health effects of smoking. Among other things, the research could determine the proportion of the population most at risk, potentially a powerful piece of information.

--Finally, someone will eventually get around to this kind of research. Wouldn't it be better to be leading it?

Company
Philip Morris
Author
Johnson, Michael (Burson Marstellar, London, Dir. of Media)
Director of Media, Burson Marstellar, London
Recipient
Greenberg, David I. (PM Gov't Affairs VP 1990, VPCorp. Affairs, PM EEMA Region 9)
Vice President PM USA 1989
Region
United Kingdom
Belgium
Named Organization
Amersham International (biotech firm based in the UK)
Litigation
Iwoh/Produced
Named Person
Bourlas, Manuel "Manny" C. (PM Science and Technology VP )
1994 Neuchatel, Switzerland. VP Environ & Oper Compl in 1993. VP Science & Technology from June 7, 1993 to May 24, 1994. Member of PM Ventilation Task Force. Reported to Steven Parrish, Senior Vice President, PM External Affairs 1994. Represented PM interest in international markets.
Type
LETT, LETTER
Subject
health belief
liability

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Page 1: zwh13e00
17/10 '96 13:44 FAX 41 38 32 77 76 Burson-MaY'steU.er ?-1-20 Biaom:r~~~n. W3v Landotj VVCt K 2PX TmlCphona: pi7t$Zt G2(ii Fac9ir.jh;: 017t.t3D 1033 i i 25th September 1996 Dtavid Greenberg Vice President Corporate Affairs Europe Piilitp Morris CAE Rue Joseph IL, 166 B-1000 Brussels Dear David At G L~, I+--t LI, An advanced biotech research organisation in the UK, Amersham Intetnational, is involved in the genome project -- the long term effort to jdentify aiI human genes- Through a friend of mine, I have discovered a possible Amersharn project that could have an impact on the tobacco industry. You may be miles ahead of me in this area, but I thought it Was important enough to pass aIong, just in case. The point of this project would be to help indilw%eduals understand their genetic susceptibility to disease related to smoking. Since we all react differently to the effects of smoldng, it obviously would be useful for each person to know whether or not he or she carries the genes that make ill effects likely. This work could be interesting to Philip Morris for at least three reasons: A simple test might eventually be devised to tell a smoker whether or not he is at risk. This would put the burden of any consequence from smolattg on the indivi.duai, and would clear the way for the non susceptible population to smoke with a clear conscience. • Philip Morris would be seen to be contributing to research into the health efFects of smoking. Among other things, the research could determine the proportion of the population most at rislS potentially a powerful piece of information. • Finally, someone will eventually get around to this Idnd of research. Wouldn't it be better to be leading it? aarc.nona • l~russct_. • 6udao-9-zt - Coorra.agi-,n • FranEfurt - ThC H..?ua • Hano u~ Londnn - t.ied r a r.7dsn • Mo:e•.nsro Oalo • Purig - I+r.iyLt.a • Rom-I • Stockttolrm • War73w .G:o whoU,-o.r+nq:1 offie4s tnroughout oSia •%.ue:ratia • Norlli ainWlca - Szutn 4.n•.ues S&T Neuchatel ---> CARCHMAN R- PM Q008/009 I andnn no. GDt529 Eq J•I, 4i)n.r 59 Y; +s;
Page 2: zwh13e00
17/10 '96 13:44 FAX 41 38 32 77 76 33urs on -Marsteller 2 David Greenberg 25th September 1996 S&T Neuchatel -+y-. CARC Aecording to my friend, pharaiaceutical companies are already investing massively in research into genetic association with certain diseases. As you may know, genes indicating susceptibility to breast cancer and prostate cancer already are identified. What is needed is more clinical studies to determine the relationship between gene structure and its clinical expression. As my friend puts it, we now need to triangulate three elements: the smoldng populatiott the gene structure, and the disease profile. I believe this is the area they would like to discuss. A few final words about Arnersham. Through its'US subsidiary, Arnersham owns the world's leading producer of gene sequencing chemicals (the product is Sequenase), and is a major research lab for biotechnology and nuclear medicine. Annual turnover is about $500 million. If you care to pursue this, I would be happy to dig deeper or get Manny together with the Arnersha.m people. I know they would welcome a chance to meet. With best regards MICSaEL JoHi.vsox Director of Media cc: M Bourlas

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