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Anne Landman's Collection

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Date: 25 Apr 1988
Length: 5 pages
2046594609-2046594613
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Abstract

This 1988 letter written on Philip Morris USA letterhead was introduced as a trial exhibit recently in the United States Department of Justice (DOJ) trial against the industry. It indicates the purpose and bias of the Center for Indoor Air Research (CIAR), a group set up by the industry to conduct research on indoor air. Written by Thomas S. Osdene (Director of PM's Science and Technology Department) and sent to Samuel Chilcote (President of the Tobacco Institute) the letter states,

"I think many of us have conceptualized the ETS issue as a battlefield in which the arena is dominated by public relations and legal issues while the ammunition which is used happens to be science. It has been the purpose of CIAR, as well as its precursor, the ETS Advisory Committee, to provide ammunition in this fight."

The letter indicates Philip Morris' oppositional view of public health efforts to reduce disease caused by tobacco, and indicates the extent to which the company was willing to go to fight public health.

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As you well know, we have been concerned with the scientific aspects of the ETS issue for sometime. I think many of us have conceptualized the ETS issue as a battlefield in which the arena is dominated by public relations and legal issues while the ammunition which is used happens to be science. It has been the purpose of CIAR as well as its precursor, the ETS Advisory Committee, to provide ammunition in this fight. I believe the most important issue one needs to examine is the role that science can play in this major controversy...

I am totally convinced, as I am sure my scientific colleagues are, that the values obtained have absolutely no biological consequence; however, the key issue is that anv increase (in nicotine and/or particulates) is being now used in a political sense to beat us over the head as well as being used as a "scientific" basis for making policy decisions. Thus, I am afraid that unless we can counter the above claim and state that the very small increase of particulates and/or nicotine has no significance either biologically or to human health, we will not move far. It is my opinion that one requires a well known or, preferably, a number of well known people who would have medical qualifications to make that kind of a statement...

Company
Philip Morris
Author
Osdene, Thomas Stefan, Ph.D. (Director of Science and Technology, Philip Morris [1986])
Ph.D. in Organic Chemistry. Ten years of research when he started with PM in 1965. Worked in Chemical Research Division of PM 1965-66; Chemical and Biological Research Division 1966-69; Director of Research 1969-1984, also assumed independent position as Director of Research and Extramural Studies during these years; became Director of Science and Technology in 1984, reporting directly to Philip Morris USA Executive VP Mark Serrano. Involved with Center for Indoor Air Research (CIAR) 1988. Attended PM's Operation Downunder Conference in June, 1987. Retired 1993.
Recipient
Chilcote, Samuel D., Jr. (TI President (1981-1997))
Chilcote has knowledge of The Tobacco Institute's and the tobacco industry's participation in public fraud and disinformation relative to health hazards of tobacco use, in the manipulation of nicotine in tobacco products and in marketing of tobacco products to children.
Region
United States
Named Organization
Center for Indoor Air Research (CIAR) (Industry formed/funded air research organization)
Nonprofit organization funded by the tobacco industry. CIAR was formed in March 1988 by tobacco companies "to sponsor "high-quality research on indoor air issues and to facilitate communication of research findings to the broad scientific community."
ETS Advisory Comm
Insts Communication + State Activities P
JAL
*National Acadamy of Science (use National Academy of Sciences)
Oak Ridge National Laboratory
Contract research lab; does gov't work and also takes private contracts.
TI, Tobacco Institute
Litigation
Stmn/Produced
Type
LETT, LETTER
Named Person
Wynder, Ernst L., M.D. (Epidemiologist, Sloan Kettering, Anti-Tobacco Expert)
1993 First scientist to report in 1950 on the carginocencity of cigarettes in rats painted with tar. Assistant at Sloan-Kettering Institute for Cancer Research Directed the American Health Foundation (AHF) from 1984 to his death in 1998.
DiNardi, Salvatore R. (CTR Special Projects, U of Mass., Health Sciences School)
Eatough, Delbert (Chemist, BYU, did joint research with RJR)
Hulka, B.
Husting, L.
Kilpatrick, J.
Piedmont
Salvaggio, John Edmond, M.D. (CTR Special Projects, Allergist & Immunologist, Tulane Med. )
John Salvaggio was a CTR Special Projects Researcher. (N.M. Tobacco Companies Personnel List; professor at Tulane University

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CS PHILIP MORRIS U. S. A. OPERATIONS CENTER. RICHMONO. VIRGINIA Taoaus S. Osaaxa. Pa. D. O/0[CTO/! OR 'JCIENCE ANO TECNNOLO6T Dr. Samuel D. Chilcote, Jr. President The Tobacco Institute 1875 I Street, NW Washington, DC 20006 Dear Sam: April 25, 1988 Thank you very much for your letter which I received on April 19 regarding the ETS issues. As you well know, we have been concerned with the scientific aspects of the ETS issue for sometime. I think many of us have conceptualized the ETS issue as a battlefield in which the arena is dominated by public relations and legal issues while the ammunition which is used happens to be science. It has been the purpose of CIAR as well as its precursor, the ETS Advisory Committee, to provide ammunition in this fight. I believe the most important issue one needs to examine is the role that science can play in this major controversy. As you well know, on a number of occasions over the years, we have generated data by measuring particulates as well as nicotine and other gases in smoking versus nonsmoking situations. In every case we have seen the following phenomenon: namely, that the amount of particulate as well as nicotine in a space in which smoking is permitted or is taking place, has a very slight increase over that of the controlled (nonsmoking) space. The increase is really quite minuscule. In addition, most of the studies done by others have often been conducted poorly thus yielding questionable results. I am totally P. O. BOX 26603 RICHMOND, VIRGINIA 23261 f80a1 27a-2692
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Dr. S. D. Chilcote 2 April 25, 1988 convinced, as I am sure my scientific colleagues are, that the values obtained have absolutely no biological consequence; however, the key issue is that any increase (in nicotine and/or particulates) is being now used i n a pol i ti cal sense to beat us over the head as well as being used as a "scientific" basis for making policy decisions. Thus, I am afraid that unless we can counter the above claim and state that the very small increase of particulates and/or nicotine has no significance either biologically or to human health, we will not move far. It is my opinion that one requires a well known or, preferably, a number of well known people who would have medical qualifications to make that kind of a statement. This person or persons would make the statement, after reviewing the experimental results obtained from the literature, that exposure to the levels measured, even over an extended period of time (e.g., in aircraft--the Piedmont study as well as the JAL study and also the restaurant and workplace studies), will not affect human health. The difficulty, I believe, is finding a suitably qualified person or persons who would be willing to make meaningful statements based on the results of our studies in the United States. Perhaps the answer is that we might be able to move towards this goal more easily in Canada or overseas. The thought occurs to me whether the former Medical Directors of T.I., who used to be on your staff, would be willing to make such factual statements on results obtained. I strongly bel i eve thi s i s key to the whol e ETS i ssue, si nce the only thing that the science can provide us with is actual (or real life) measurements, while it is the interpretation thereof, whether rightly or wrongly, that is now being used in the legislative and political processes. Having stated that, which I believe is basic to the issue, I would point out to you that CIAR and its precursors have addressed a number of the questions which you pose in your letter to me. The analysis of research critical of ETS: As you are aware, we have once again revisited Hirayama and we will pursue this with great vigor. The reason for the importance of relooking at Hirayama is because it is this database which I believe forms the pseudo-scientific basis for the push against ETS. As you know, the results of several studies, I believe 11 or 13, were subject to "meta analysis" by the National Academy of Sciences (NAS) panel. This is the addition of all of these studies regardless of their merits and then pretending there is a scientific trend. 3
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Dr. S. D. Chilcote 3 April 25, 1988 Since Hirayama contributed the majority of the total database, if we could show that Hirayama's data is not correct, this certainly might change the scientific environment. However, even if we show that Hirayama's results are inappropriate or misused, the major question still arises, how is this going to be used to defend our position? I believe once again we will be depending on a spokesperson who has suitable qualifications to do this. There have been additional analyses done over the period of time and I would remind you that recently a study by Dr. J. Kilpatrick, which was presented in Japan, reanalyzed some of the Hirayama data. In addition, we have had Dr. L. Husting undertake a study which looks at the epidemiology of low risk associations as determined by the case-control method. As I am sure you have heard Dr. Ernst Wynder at the ETS Meeting in Tokyo also gave some cautionary comments about this type of epidemiology. I might, however, say that Barbara Hulka, who was the Chairman of the NAS panel, seemed to be totally impervious at the Tokyo meeting to any suggestions made by Dr. Wynder. Therefore, I would think it would be very difficult to get her or members of her group to change their minds because, frankly, I do believe that the attitude is "please, don't bother me with facts." In terms of the second issue, Sponsorship of research into alleged health effects of ETS, with the exception of some work by Dr. Salvaggio we have avoided this issue. I would remind you that there were restrictions placed upon us over the period of time regarding any determinations of any smoke components in body fluids. This, I believe led to discouragement of doing specific experimentation of this area. The next subject, Sponsorship of research into overall air quality, was and continues to be a major thrust of CIAR's work, and I would remind you that we have undertaken a number of studies in aircraft (mentioned above) as well as workplace and restaurant studies undertaken i n New York, Da11 as, and now to be done i n Washington. In all of these, the levels of particulates and nicotine, and to some extent carbon monoxide, were determined. Philip Morris has undertaken some studies in railways in the New York City area. In addition, CIAR has sponsored work with Dr. S. DiNardi in which he has looked at the overall air quality (with emphasis on respirable suspended
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Dr. S. D. Chilcote 4 April 25, 1988 particulates) in shopping malls and offices, as well as studies undertaken at the Oak Ridge National Laboratory evaluating personal nicotine monitors. The project with Dr. D. Eatough is directed at trying to understand the relationship between a nonsmoker's exposure to ETS and the dose actually received, - as well as to investigate additional chemical markers for ETS in indoor environments. I am quite sure if you wish, we could give you greater details about these, but I think for the purpose of this letter this summation is sufficient. I believe that if we continue down this line, and we must, then it is vital that there be a unified position and an appreciation of the role that science and therefore CIAR can play in this controversy. I believe further that the frustration which is felt by all of us is uppermost in the minds of members of CIAR. You are aware that we have had problems regarding the selection of an Executive Director and in addition, it has been difficult to plan a program which will give rapid results in a short time span. It is my opinion that CIAR originally was not intended for providing short-term results; nevertheless, we are vigorously pursuing the avenues open to us and we will certainly seek any input from you and your groups regarding this. In terms of Communication with the scientific community related to ETS and overall indoor air quality, there are two points. 1) It has been our wish and intention that we establish: a) a newsletter; and b) perhaps more importantly, get access to or form a new journal for the entire question of overall air quality. This of course would be a peer review journal. I do believe that the time to establish this and to get material published with due speed is however still a long way off. Unfortunately, I cannot think of an effective way to cut the time in conducting good studies and in turn getting their results rapidly published in a scientific journal. 2) I believe it is very important that we recruit other industries which have interest in the question of indoor air quality, and I believe that this is another function which CIAR must undertake. However, this can only be done if we broaden our areas of research to include studies not solely related to ETS. The CIAR board plans to meet in early May and spend two days reviewing what has been achieved, and more importantly agree upon what needs to be done in the future.
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Dr. S. D. Chilcote 5 April 25, 1988 I trust that these comments will be of some assistance to you in the context of the overall ETS program. Please be advised that my need to appear in New Jersey sometime in the very near future may well prevent me from joining you at the meeting of the Institute's Communication and State Activities Policy Committee. Nevertheless, feel free to call on me or any members of the CIAR board if we can be of any help. Sincerely yours, bc: F. Resnik M. Serrano xc: R. Pages

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