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i ° TOBACCO RESEARCH Telephone : O1 - 828 20-1.1 TelccJrams: l~bcom.London, 5.W~. 1. COUNCIL G|¢n House. S~acj }'lace, London, S.W, 1. CONFIDE NTIAL Dr. R. Comber. 16th February, 1971. /I ,1 Dear Sir, S.B.S.G. Letter No. 148 I have pleasure tn enclosing copies of the following papers :- Application for an extension of their Research Grant from Dr. A.E. Williams and Prof. H. Smith of the University of Birmingham (J 203) o Progress Report for the period June 1970 - December 1970 from Miss Diana S, Davis and Dr. A.E. Williams (J 204). , Addition to the Hyperplasia Progress Report from Dr. R.F. Davies (J 21,1). Yours faithfully, D.H. Beese, Secretary. Encs. ~XD ~O

% TOBACCO RESEARCH Telephone: O1-828 2041 Telz ~eams: Tobcom. I.ondon. S.W. 1. CONFIDENTIAL Dr. H. Comber, COUNCIL Glen Hous~. S)ng Placc, London 0 S.%V, t. 4th February, 1971. f Dear Sir, S. B. S.G. Letter No. 147 Combined S. B. S. G./S. M. S.G. Meeting I should like to confirm that the combined meeting arranged for 10th February has been cancelled. Next S. B.S.G. Meeting The next S.B.S.G. meeting will be at 11 a.m. on Tuesday, 9flt February at Glen House. Luncheon will be available. The following papers are enclosed for consideration at the meeting :- , 2. Age nda Item Agenda (J 174) p Paper by P.N. Lee and J.A. O'Neill on the effect both of time and of dose applied on the turnout incidence rate in skin ~l~JntJng experiments with Benzypyrene (J 173). 4 (n Yours faithfully, D.H. Beese, Secretary. E ncs. CD CD

I L TOBACCO RESEARCH Te.]e-phone : Ol" 82B 2041 Tzlegr~ms: Tobcom.London, 5.W'.I. COUNCIL Glen House. Slug Place. London, SAV. I. CONFIDENTIAL Dr. R. Comber 2rid February, 1971. Dear Sir, S. B. S.G. Letter No. 146 Next Meeting The next meeting of the Skin Bio-Assay Study Group will be at 11 a.m. on Tuesday, 9th February at Glen House. Luncheon will be available. An Agenda for the meeting wiU be circu.lated later. Copies of the following papers are enclosed for consideration:- . 2. Harrogate Hyperplasia Progress Report, February 1971 (J 130) Harrogate Tlssue Culture Progress Report, February 1971 (J 131) 3. Final Analysis of Experiment 1. I. 7.4. (J 151) / Encs. Yours faithfully, D.H. Beese, Secretary. CZD cZD cZZ) J

• o TOBACCO RESEARCH Telrpho.e : 01- 828 2041 "Felzgz.am.1: Tobcom.London. S~.I. CONFIDENTIAL Dr. R. Comber. COUNCIL Glen House, Slog Place. London. S.'V~: 1. 18th December, 1970. Dear Sir, Next Meeting S.B.S.G. Letter No. 145 I should like to confirm that the meeting arranged for 12th January, has been cancelled. There will be a meeting of the S. B. S.G. on Tuesday, 9th February at 11 a.m., and ou Wednesday, 10th February at 11 a.m. a combined meeting of the S. B.S.G. and S. M. S.G. Paper for information : Analysis of Harrogate I.C.I. mouse experiments by four-methods. (H 1698). Yours faithfully, D.H. Beese, Secretary. Enc. O F~

• TOBACCO RESEARCH. "re~pho.c : Ol - 828 2041 "l'elcgr.m~: Tobcom. Lol*do.. 5)A:l COUNCIL Glcn }lou.-¢c, Stag l'lacc. London. Sit" I. CONFIDENTIAL Dr. R. Comber 26th November, 1970. Dear Sir, S. B. S.G.I.e.ttnr No. 144 I have pleasure in enclosing a copy of note~ dated 5fi~ Novembe.r by the Director on a meeting with Drs. C. Izard and C. Lib~rman of S.E.I.T.A. on 29th October (It 1494). Yours faithfully, D.H. Beese, Secretary. / I Enc, 0 cZ~ c:Z)

TOBACCO RESEARCH Telcphonc : OI - 82/3 2041 Telc,jr(m~ : Tobeo,*. London. S.W. 1. CONFIDENTIAL Dr. R. Comber, COUNCIL Glen Ilousc. Stag Place. London. S.W.t. 3rd November, 1970. Dear Sir, S. B.S.G. Letter No. 143 I have pleasure in enclosing copies of the following papers :- 1. Minutes of the S. B. S.G. meeting held on Wednesday, 14th October (H 1467). 2. Paper on the relevance of T. P.M. Yields and Sldn Painting (H 1478). Paper by Dr. R, F. Dav~s et al I am pleased to inform you that the paper (H 923) "Pulmonary adenomata induced by carcinogen treatment in organ culture. Irufluence of increasing amounts of carcinogen" by R.F. Davies, I.R. Major and Elizabeth R. Aberdeen has been accepted for publication in the British # Journal of Cancer. I will let you know as soon as we know in which issue it will appear. Yours faithfully, D.H. Beese, Secretary. mucs. CD O

• . TOBACCO RESEARCH TeJ~phone : 01- 828 204t Tele91-ums: Tobcom, London. S.W 1. COUNCIL Glen House, Slag Placc, London, S.1,~. 1. CONFIDENTIAL Dr. R. Comber. 23rd October, 19"/0. Dear Sir, S.B.S.G. Letter No. 142 I have pleasure in enclosing copies of the followirg papers :- i. Paper dated 19th October from the Imperial Tobacco Group Ltd., on the Drikold versus impact/on traps : Mouse Skin Painting Results (H 1430). 2. Notes dated 20th October from Dr. R.F. Davies on the International Symposium held in St. Lukes Hospital, Chicago, front 15th - 17th October, 1970 (H 1431). Yours faithfully, D.H. Beese, Secretary. t ,/ Encs. .,,..,a. 0 U~

TOBACCO RESEARCH Telephone : O| - 828 2041 Teleg2,ems : Tobcom..Lo-don. S.WA. CONFIDEhrrIA L Dr. R. Comber COUNCIL Glen House. Sta9 Place, London, S.%~,: I. 8th October, 1970. Dear Sir, S. B. S.G. Letter No. 141 Next Meetin~ The next meeting of the S. B. S.G. will be at 11.00 a.m. on Wednesday, 14th October at Glen House. Luncheon will be available. Copies of the following papers are enclosed for consideration:- ° 2. , Agenda (H 1367). Set of Tables (H 1363) bringing up to date the information contained in document H 1166. Notes dated 14th July by the Director on a discussion with Dr. R.S. Doll ou Wednesday, ! 8th July? 1970 (H 1013). Paper dated 3rd March by Dr. R, F, Davies on the study of changes in platelet behaviour in the cat ~" 323). Yours faith~lly, D.H. Beese, Secretary. Agenda Item 5 (a) 8 11 a EDcS. ~rl 0

• .° TOBACCO RESEARCH "rch,pho~,c: Ol- 828 204! TeJc~jvL[m~ "]'obcom, Lond~.,n. SW.I CONFIDENTIAL Dr. R. Comber COUNCIL Glen tlou~c. S~ag Ptacr. London, SA%'. 1 7th October, 1970. t I °, Dear Sir, S. B. S.G. Letter No. 140 I have pleasure in enclosing copies of the following papers: 1. Pzper by Dr. K. Rothwell on Experiments 1.1.3.20 to 1.1.3.22 (H 1166) 2. Paper dated 1Sth September from Mr. W.S. Paige on Dose Levels in Mouse Skin Painting Experiments (It 1319) 3. Progress Report from Dr. R.F. Davies on the Organ Culture Department at Harrogate (H 1357) 4. Progress Report by Dr. R.F. Davies on Cell Kinetics (H 1358) Yours faith~ully, D.H. Beese, Secretary. EIICS. 0 L~ L.N (..3"I 0