Tobacco Documents Online

7 pharmacy has been associat~ with the ac~inistration of drugs by inhalation. The planned administration of drugs by using cigarettes would bear exan~nattono Again, work on the physiological effects of nicotine might wail lead to analogous therapeutic possibilities. But any bonus, however high'is insufficient in itself to Justify the research progzau~e. If it were decided to extend considerably tesearch in the heelth fteld, on whatever basis~ one of the difficulties if not the pzL~e difficulty would be obtaining suitable qualified staff. It is worth a thought that in certain circumstances financial diversification could be used to provide incidentally~ready~nade nucleus of a biological ¢ research unit which could be redirected towards our own problems., / The total expenditure on research in the ~obacco industzv is zelattvely small. Present difficulties are forcing the industry towards a more technical basis. While I would expect the industry to spend "large sums on diversification and on public zelations~ Increased expendttuze on ~health" research would not appear unreasonable and would begin to measure up to the problem. In sugary, any policy changes or developments can only be considered against the whole background of Company activity but, if it were decided as a matter of policy to enlarge the research effort on s~oking end health, I would suggest the followtngl t) The resources of Harrogate should be planned for considerable extension Immediately. it) The T.M.S.Co programme should be ex~ended and the labo~a~ozies put tnto• position for creative work by giving the directing staff permanent positions and a suitable budget. iii) The work of R.& D.E.~ Southampton, should be expanded to accelerate wozk pazttculazly on phenols, polyphenols and polycyclics. iv) On the short tez~ level the study of the influence of stem and stm extracts on taste and flavouz could be speeded up without increased expenditure.

v) I£ the B-AoT. policy weze modified to aItow biological wozM on a Company basis I would zecomend that we use outside animal testing on low B.P. c~garettes imedtately. vi) In the event of such a poltc¥ change I would zecommend that we tackle ciliary inhibition at R.& D.E.~ Southampton. # Immldl