Tobacco Documents Online

.4 A « Research Recommendations on Environmental Tobacco Smoke Recommendations for research from the three most recent conferences on environmental tobacco smoke are summarized below. The suggestions are listed without regard to priority, but note that several research recommendations occur in more than one conf'erence., The origin of each suggestion is designated'in parentheses. The three conferences include: I. ETS-Environmental Tobacc Smokes Report from aiWorkshop on Effects and Exposure Levels, University of Geneva, Switzer- land, March 15-17, 1983; II. Workshopion Respiratory Effects of'Involuntary Smoke Exposure: Epidemiologic Studies, U.S'. Department of'Health and Human Services, National Institutes of Health, May 1-3, 1983'; III. Symposium on the Medical Perspectives of Passive Smoking, Vienna, Austria, April 9-12, 1984'. Recommendations: 1. Determine the relationship of environmental tobacco smoke under realistic conditions with that of analytical smoke measure- ments of sidestream smoke ( I),; 2. Evaluate the effect of time on environmental tobacco smoke composition and concentration ('I); 3. Measure nitrosamines, polycyclic hydrocarbons, acrolein and' formaldehyde ('components which have not been frequently or adequately measured in environmental tobacco smoke). Methods shouldibe developed to determine what fraction of these constitu- ents can be related specifically to cigarette smoke contributions (,I) ; 4. Examine the relationship between ambient levels of tobacco smoke and personal exposures, using both area mea5urement devices and personal sampling, devices (I)I ; 5. Develop practical methods for measuring the exposure of childreniand infa~nts, (!I, II, III); 6. Develop chemical dosimeters and'biochemical markers for easy and reliable measurements of ]longrtenn,, average exposure to environmental tobacco smoke (I, II, III);

C , ~. w ® f ! 7. Develop standardized questionnaires for precise estimation of current environmental tobaccosmoke exposure. Questionnaires ~ should include items concerning exposures to other relevant substances, e.g., indoor pollutants (II„ II, III); 8. Establish standard methods for sampling and analyzing sid'e- stream~and environmental tobacco smoke (I, II);. 4 9. Identify individhuals who are "sensitive" to environmental tobacco smoke and characterize the acute effects fromitobacco smoke exposure (I)i; 10i. Pursue follow-up~information,regarding,children"s chronic lungidisease!and disorders which are now hypothesized to belinked with indoor air exposures (I', II); 11. Increase usage ofr'case-referent studies which would include information on tobacco smoke exposure as well as consideration of other possible indoor sources off'pollution (I, II, III),; 12'. Initiate the "bio-monitoring" of subjects with emphasis on bronchial mucosa examinations, metabolism rates of tobacco products, measurement of endogenous formation of carcinogens and the examina- tion of effects of estrogen levels and diet on tobacco smoke metabolismi(III);. 13. Monitor individuals in occupations under typically high exposures, e.gi., waitresses, bartenders, ('III); 14. Compare disease rates in individuals exposed to environmentall tobacco smoke to those who are currently pipe and cigar smokers (III)';. 15. Encourage the use of'common and standardized methods of analysis for the various research groups with ongoing pulmonary function and pollution studies (IHarvard, Tecumseh, Tucson)I(II); 16. Measure bronchial reactivity and atopic status using skin tests and analysis of'serum IgE from exposed individuals (,II),; I 1 I - .

. < .: ~ -~ . +A'. T 44 , -Z