Filter Ventilation and Design
Subject: Estimation of Nicotine Deliveries with Filter Nicotine Data
Abstract
Attaches data illustrating that change in filter efficiency with change in smoking parameters affects prediction of nicotine delivery from filter nicotine measurements. Notes observations that smoking patterns differ by age and gender, and deducts that "the average nicotine filter efficiency differs among demographic groups." Concludes that nicotine delivery, therefore, cannot be estimated from filter nicotine data unless smoking parameters are also measured.
Fields
- Type
- Letter
- Chart/Graph/Table
- Company
- R.J. Reynolds
- Author
- Townsend, D.E.
- Stowe, M.E.
- Recipient
- Dube, Lynn
- Perfetti, Tom
- Copied
- Henley, W.M.
- Reynolds, J.H.
- Named Person
- Reynolds, John
- Thesaurus Term
- Nicotine Level
- Filter Efficiency
- Smoking Parameters
- Demographics
- Filter Efficiency
- Indexer Comment
- Document set 1
Document Images
I n°UJ °n3
Subject: Estimation of Nicotine Deliveries
with Filter Nicotine Data
To: om Perfetti
Date: April 15, 1982.
From: D. E. Townsend
M. F.. Stowe
Lvnn Dube
,
Use of filter nicotine level to estimate delivery to the smoker requires
that the percentage of nicotine removed from mainstream smoke by the
filter (i.e. filter efficiency) be known. Since the filter efficiency
is dependent on smoking patterns (puff volume, duration, frequency,
puff profile, or butt length), the results of filter nicotine measure-
ments may be used to estimate nicotine delivery only when measurements
of smoking patterns are also obtained.
The following data taken from a recent study of the effects of smoking
parameters on delivery for NOW 85 cigarettes illustrate how the change
in filter efficiency with changing smoking pattern will affect prediction
of nicotine delivery from filter nicotine measurements. RSM models
developed in the study show that a nicotine delivery of 0.15+0.01 mg/cig.
may be obtained with various combinations of puff volume and frequency
while the filter nicotine level ranges from 0.29-0.51 mg/filter. Also
it can be shown that with various combinations of puff volume, frequency,
and duration, a filter nicotine level of 0.5(}+0.01 mg/filter may be
obtained while the nicotine delivery ranges from 0.15-0.40 mg/cig.
These examples neglect other important smoking parameters such as butt
length and non-uniform smoking frequency and therefore should be regarded
as conservative estimates.
In recent studies, Dr. John Reynolds has observed differences in smoking
patterns by age and sex. Since nicotine filter efficiency is a function
of these smoking patterns, it follows that the average nicotine filter
efficiency differs among demographic groups. Thus, an ad ional source
of error may be introduced in the estimation of nicotine'de ivery from
filter nicotine values if the sample of smokers is not demographically
balanced.
Clearly, unless one also measures smoking patterns, nicotine delivery
cannot be estimated with filter nicotine data.
dd
xc: Dr. W. H. Henley
Dr. J. H. Reynolds
RJRI FORM 2422- Rev. 7/70
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