Tobacco Documents Online

- M E=M 0 R A N D U M RE:- ENVIRONMENTAL TOBACCQ-SMOKE--NONSMOKER RESEARCH FROM: DONALD K. HOEL DATE s MAY 9, 1975 . r. ------------------------------------------------------------- On April 25 a meeting was-held at the Conference- Room of CTR-attended by Dr. Frank G. Colby, Dr. William L. Dunn, Jr., Dr. Raymcnd Fagan, Timothy M. Finnegan, Dr. Ivor W. Hughes, Edwin J. Jacob, Patrick Sirridge and Donald K. Hoel. This group discussed the "environmental tobacco-smoker-nonsmoker" research situation,-both in Europe and in this_country, It was the unanimous opinion of the group that there appeared to be a pressing need for industry-sponsored research-in this gen- eral area_to produce objective and high quality scientific data to meet-current legislative and scientific challenges and-to correct misinformation. Various antismoki-ns activities designed to make smoking socially unacceptable were also discussed. - General areas where-there was a need for quality research were identified and the-attached proposed outline indicating = research areas was-agreed upon. A few spe,:.ific research projects- were discussed but the group made no assessment and felt it premature to-expreas an opinion concerning the priorities o-f research projects within the general areas indicated_by the suggested outline. Many of the group had specific projects-and/or individ- ual researchers or institutions to recommend in some of the proposed research areas. It was also suggested that consideration should be given to repeating certain research studies previously completed outside of the U-S. Agreement was expressed=that - the industry would benefit by an organized approach to the over- all research effort. If the Research Liaison-Comrrittee agrees with this asS°ssr.^ent, then t}lis-C5r sor.f'_ otl'•.f`Y 1L"olli. Jh'_iulCi I)G* c°.ll}}iol:? 7o;l. ~-~o rll •-f. ~~~=., - ;..rio__- ~i i: 4 .. 4 •}•a i __ r. s a ~ "' : C•~:~ :t. l i~ - i i- ~ :• ~~r ~. to UC_'.vel'vU speCi=ic t7rCiDo:;u1:i fJr co?lS -C:'a .ZL?.ol: !J~' tht: Liaison Comsnittee for funding through an appropriate source. DKH:sh O 1-~ +A 0 ~ O (b

SUGGESTED AREAS OF' RESEARCH - I. Health. A. - Studies of specific groups--environmental experimental exposures. and possible 1. - Healthy children--home exposuree .2. Healthy older people. - 3. Physically compromised individuals (those suffer- -ing from preexisting cardiovascular and lung dis- ease and those with-"small airway obstructions"). 4. Pregnant women.- B. Tobacco smoke as a possible allergen. 1._ Determine whether true tobacco smoke allergy exists and establish medical iden-tification of - such individuals, if any. - 2.= Determination of the number or size of the popu- lation affected. [The employment of new techniques to identify true tobacco smoke allergy and-to estimate the number of allergic persons is anticipated.-; C. Exposure of humans to-certain tobacco-smoke constituents and other environmental substances. 1. COHb levels. 2. Nicotine absorption. - 3. Other substanc_es not found irn tobacro- smoke . 4. Effects of chronic lo--7 level exposur-e to selected cons l L:"i!t- s in C -.'r,Tcl~_T` porlll.at.LC:' L7:CC,'.ips. [Utilization of both dose-response and compara- tive studies has been suggested.] - -

II. Annoyance. A. Physical irritation (i.e., eyes, nose, throat, etc.). B. Cognitive or psychogenic irritation. C. Investigation of comparative annoyance in humans. D. Acclimatization in various situations. - - 4L III. Atmosphere characterization and measurement programs. A. Determine levels of specific substances in controlled - - experimental situations. BE Determine levels of specific substances in'public places under various circumstances. - " [A and B to include identification and contribution from other sources.] C. Examination of the physical makeup-and qualities of sidestream tobacco smoke.