Tobacco Documents Online

'I'lu: Cm•.Nrir.Fo,ie'Dimwc-() I.c-. GRA:.°: APPLICATIO:. :YJ . 1161 Pi-iAR]•:ACOLOGY HN12236001 d July 19, 1977 14` ~;Z6,730 ia~~,jpzc ' b • TO: The co*resittee cosprisinE Drs. Gardner, Meier and Sonusez^s SUBJECT: A. b1. Tosets'r.o, Ph.D., Litron Laboratories Ltd., Rochester, N.Y. ',dei•: application No. 1161 "Probing ?:icotine Receptor Sites" irTS2,''RY This application was solicited by Dr. V. F. Lisanti. Letter of inquiry approved by Executive Cor.ffnittee. The proposed work will involve the synthesis of special nicotine and piperidine derivatives for specific uses in collaborative studies with Drs. Abood and Snider at the .^.enter for Brain Research, Rochester. T:is proposed reso~:.rce will greatly assist and extend the investi- gations bein~; underlaken by Dr. Abood and other CTR investigators on r.ieotine recebtors and binding sites. REebFST Application No. 1161 requests $26,730 for the first year of a three year project. Estir,ates for thc second and third years are 526,333 and $30,033, respectively. DOCU'•--':TS sdB~LTTrD (attached) 1. Application dated June 3C, 1977 (24 pages including Appendeces I and II) 2. C1' of Dr. Tometsko (6 pages) 3. Reprints (6 in nunber) 4. Manuscripts (2 in nuraber) C06S•G; ;'T The low overhead rate has been requested and apnroved by Litron Labs, as proposed in discussions. DS/p Encls David Stone !