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THE COUNCIL FOR TOBACCO RESEARCH-U.S.A., INc. January 26, 19'l8 (RiANT APPLICATION 1W . 1135Fa PUfWNARY H1612211068 TO: The coshi.ttee comprising Drs. Bing, Gardner ani 2caamers SiB=T: James 7.ravis, Ph.D., University of Georgia, Athc?rds, Georgia First renewal application No. 1135R1 "Proteolytic Enzymes and Inhibitors in Elnphysema" kII5'I+ORY The Council has supportedd this applicant since J`d].y 1, 1972. In March 1 j75 the SAB approved a tlaree year Continuation grant entitled '$iochemistry of Chronic Obstructive Lung Disease". Application No. 1135, a collaborative project be;tween Travis and Powers (with title change as noted above) was approved by the SAB in March 1977 and superceded the third year of the Travis project. Approval for the first year.was in the amount of $85,311.00 (as requested). Estimates,for the second and third years were $76,065.00 and $85,678.00, respectively. (In May 1977, 7ra•ris mas awarded a supp].esental grant (CTR No.11355) iA the amount of $7,200.00 for the purchase of a preperative ultracentrifuge). REQUEST Application No. 1135'~.l (second year of the collaborative project) reque'sts a total of $83,052.00 (ie. $41+,297.00 for Travis and $38,755•90 for support of Powers ) . DOCLMENTS SIBMITTED (attac hed ) 1. Application dated January 6, 1978 (13 pages) 2. Progress Report No.6 for the period November ].5, 1976 - December 15, 1977 (7 pages including face-sheets). 3. Reprints (2 in number -- both acknowledge CTR). CONMENTB 1. As progress appears to.be satisfactory, this request will be handled administrative]y and withheld from the bulky SAB agenda for the Apri1 1978 meeting, unless you object. 2. Rravis has requested $3500.00 for the purchase of an automatic converter for the amino and sequencer (see page 2 CTR app].icaticm form) 3. Travis has requested $800.00 for foreign travel.....possibly this holds for Powers as well. , David Stone DS/1p