Tobacco Documents Online

. . 6 ~3 3 .• Txr•: C'oLP& FQeTosacco REsi:ARCH -U.S.A., Irc. MUCRAN-um GRANi' APPLICATION NO. 1143A TO: SUBJECT: HISTC4tY Ju1y 10, 1979 f `r A . . ;,) ti I llt?~ ~ Sicnr Li5•) Y ~ The committee comprising Drs. Gardner, 1Nei and Scmomers r z., r ;3• Aaron Janoff, Ph.D., State University of New York at Stony prook, Stony Brook, New York 11794 Continuation Application No. 1143A "Flarther Studies on Suppression of Protease-inhibition by Cigarette Smoke" Application No. 1143 entitled "Part 1...Suppression of Proteinase Inhi- bitian by Components of Cigarette Smoke: Part II...Induction of Alpha-l-Anti- trypsin Synthesis in Liver Cells", was approved by the SAB in April 19'/7 for a two year period, as requested. Application No. 1143R1 (second year of project) was approved by the SAB in April 1978. In April 1979 the SAB approved a one year request (Grant No. 1259) entitled "Immnologic Assay of Lung Elastin Degradation". REQUEST Continuation App2icption No. 11L3A requests $15,63k.83 for the first year of a two year pro3ect: Budget estimate for the second year is $21,195. yOCUId;NTS SUHaTTTD (attached): 1. Application dated June 18, 1979 (11 pages) 2. CV of Dr. Janoff (11 pages) 3. Progress Report No. 3 for period Decealber 10, 1978 to June 3, 1979 (11 pages with.Face Sheet) 4, Reprints '(2 in number - both acknowledge CTR) 5. Manuscripts (3 in n0ber - all acknowledge CTR) David Stone Attach. DS/am