Tobacco Documents Online

Trtr••. Cocxc'rr.Frrtt ToISacco Iir.sr:~r:cr[-U.S.A.. Itic. A&.. -;a - _J_,V.. May 28, 1976 HN00 7 0 7 0 2 3 GRANT APPLICATION No. 1087 PHARMACOLOGY TO: The Executive Committee of the S.A.B., Drs. Sommers, Bing, Gardner, Jacobson and Wyatt SUBJECT: D. M. Turner, Ph.D., Hazleton Laboratories Europe Ltd., Harrogate, Yorkshire, ENGLAND. New application No. 1087 "Buccal absorntion of labelled nicotine in the anaesthetised cat from cigars as ce.apared to that from cigarettes." HISTORY Hazleton Laboratories Europe, Ltd. is successor to Tobacco Research Council Laboratories. They now conduct research for the 7iiC under contract but are free also to accept projects from other organizations. Dr. Turner has been on the TRC staff for many years and collaborated with Dr. Alan K. Armitage in.much of the nicotine research carried out there. Dr. Armitage is now Scientific Director of the new organization. Their qualifications are shown in the attached documents which include curricula vitae and twelve reprints. Dr. Armitage sent C.T.R. a letter of inquiry,in January 1976, too late for consideration at our March SAB meeting. It was handled as Case No. 362 and by telephone vote, an application was encouraged. It was agreed that this would be considered at the next meeting of the Executive Committee, which has now been set for June 11. REQUEST The total request is for $18,500 and the time estimate for the entire study is four to five months; starting date -- 8eptember 1, 1976. DOCLR4ENTS SUBMITTED (attached) 1. Application received May 21, 1976 2. Brief CVs of Drs. Armitage, Turner, Houseman, MacDonald and of Mr. Hopper 3. Protocol for experiments 4. Method for preparation of C14 labelled nicotine, (which has been used before ) 5. Reprints of twelve pertinent papers COMMENT Because of the short time requirement for this study and its modest cost, as well as its relevance, it was sugEested by Dr. Gardner that thE Coimaitt?e might be able to take action on June 11. NOTE: The reprints are a11 worth reading as indicative of the kind of work that has been done under Dr. Armitage's direction and of the kinds of skills that have been developed. Please return amy of them vou ma not wish_to keen in vour files. Ap R.C.ti.