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..~ PHILIP MORRIS U. S. A. IN7ER-OFFICE CORRESPOMCENCE eICNMONDo IIINOINIA To: • CTR File Date: October 25, 1978 fro~: • R. B. Seligman • sv-j•ct: • CTR Yeeting - October 18, 19, 20, 1978 :• I discussed the recent CTR meeting with Preston Leake. As Chairman of the Industry Technical Committee, be was present at the grant approval meeting of CTR. AS a matter of background, Preston indicated that at the mid-1978 meeting Ed Jacobs appeared to warn the SAB against approving work in the area Of CNS stimulation. The SAB reacted vehemently claiming it was a legal problem and leave the science to them. They also indicated that' they were not being paid adequately. At the most recent meeting, Ed Jacobs was•not present but Ad Yeaman said that certain grants would be "reviewed" by counsel after receiving SAB approval. The CNS study grant would certainly fall in that category. The most recent meeting went smoothly and Preston felt it was due to the absence of Ed Jacobs and 8reisher. (8reisber's employment with CTR has been terminated.) 5 £~ On the subject of the meeting itself, 50 or 60 s applications have been received. Preston indicated he had no voice in the Committee's decision but was just present to supply analytical input and to impart any other iniormation which may be pertinent to the Industry. First thing,the SAB gives approval or disapproval of the application. If the application is approved, the SAB rates the protocol on -merit and on timeliness. • These ratings are then collated ••-•-- and a final decision is made by Gardner, Eockett, and Hoyt; normally based on the funds. At the recent meeting,the controversial contract work conducted by the Idicrobiological Associates was terminated at the end of this contract year (probably June, 1979), but a grant for their two principal investigations was approved in the amount of $38,000 by the SAB. 9641 CTR IaIN 043721