Council for Tobacco Research
Deposition of Richard E. Kouri [Deposition of Kouri in the Matter of the State of Texas]
Abstract
MAR
Fields
- Master ID
- Ctrmn00043385-4499
Related Documents:- CTRMN043385-3651 Deposition of Richard E. Kouri [Deposition of Kouri in the Matter of the State of Texas]
- CTRMN043669-3670 Consultancy Agreement [Agreement to Provide Analysis of Certain Aspects of Research Performed by Microbiological Associates Inc Under Contract with Ctr]
- CTRMN043671-3674 Arch, Et Al V. American Tobacco Company, Et Al [Deposition Postponed]
- CTRMN043675-3678 Witness Fee [Check for Sixty Four Dollars and Eighty Cents]
- CTRMN043679-3689 Check 3223 [Forty Dollars and Zero Cents]
- CTRMN043690-3694 District of Columbia City of Washington Affidavit of Dr. Richard E. Kouri [Statement Concerning Involvement with Microbiological Associates Inc and Ctr]
- CTRMN043695-3695 Stages in Carcinogenesis [Diagram]
- CTRMN043696-3696 Microbiological Associates Contract 30 [Proposed Research Modification and Tentative Approval of One Year Contract Involving Effects of Cigarette Smoke Related Chemicals]
- CTRMN043697-3697 A Frank Statement to Cigarette Smokers [Response to Recent Reports on Possible Link Between Cigarette Smoking and Lung Cancer]
- CTRMN043698-3701 Chronic Exposure of Mice to Cigarette Smoke [Foreword, Introduction and Objectives of the Complete and Unedited Final Report of Contract Research Performed by Microbiological Associates]
- CTRMN043702-3702 "Suggested Distribution of Book Titled "Chronic Exposure of Mice to Cigarette Smoke"" [Listing of Possible Recipients and Number of Copies to Each]
- CTRMN043703-3710 Press Release for Mai Report [Copy of Draft for Views and Suggestions]
- CTRMN043711-3720 Chronic Inhalation Studies in Mice. II. Effects of Long-Term Exposure to 2r1 Cigarette Smoke on (C57bl/Cum X C3h/Anfcum)F, Mice Jnci Vol 77 No 1 [St 2r1 Cigarette Smoke Has Weak Carcinogenic Activity in Mouse Lung Tissue]
- CTRMN043721-3721 Ctr Meeting - October 18, 19, 20, 1978 [Controversial Contract Work Conducted by the Microbiological Associates Terminated]
- CTRMN043722-3778 Evaluation and Characterization of An Alkaline Elution Assay As A Measure of Pulmonary Dna Damage Induced by Chemical Carcinogens or the Chemicals in Cigarette Smoke [Outline of Proposed Research Includes Resume and Bibliography]
- CTRMN043779-3871 [Affirmation of Continuation of Funding While Alternative Funding Is Evaluated Contract 22 Will Continue in Present Form Transmits Progress Report]
- CTRMN043872-3951 Malignant Transformation, Mutagenesis and Fibrinolysin Production of Cigarette Smoke Condensate Fractions [Description of Proposed Research Includes Resume and Bibliography]
- CTRMN043952-3953 Conference on Human Carcinogen Metabolism: Ahh [Observations and Conclusions on Conference]
- CTRMN043954-3954 Deposition of Richard E. Kouri [Deposition of Kouri in the Matter of the State of Texas]
- CTRMN043955-4294 "Final Report "Smoke Inhalation Studies in Mice"" [Describes Facilities, Equipment, and Results]
- CTRMN044295-4296 Executive Committee and Contract Committee Meeting [St]
- CTRMN044297-4336 Proposed Studies for Ctr 0030 - Smoke Inhalation Carcinogenesis Studies in Mice [Describes Facility for Determination of Effects of Cigarette Smoke]
- CTRMN044337-4464 Progress Report for Ctr-0030 - Smoke Inhalation Studies in Mice [Describes Procedures and Findings]
- CTRMN044465-4473 [Summary of Current Research on Smoke Inhalation in Mice]
- CTRMN044474-4487 Progress Report for Ctr-0030---Smoke Inhalation Studies in Mice [Describes Recent Findings]
- CTRMN044488-4488 Official Abstract Form the Effect of Lifetime Exposure to Whole Cigarette Smoke in Bc3f1/Cum Mice [St Describes Changes in Lungs]
- CTRMN044489-4489 [Confirms Meeting to Present Final Report for Ctr Contract 0030]
- CTRMN044490-4496 [Proposal Regarding Completion of Manuscripts From Chronic Smoke Inhalation Study]
- CTRMN044497-4497 [Requests A Special Project to Provide Support for Preparation of Manuscripts Resulting From Smoke Inhalation Study]
- CTRMN044498-4499 [Transmittal of Manuscript Regarding Chronic Inhalation Studies in Mice]
- Author
- Kouri, R.E.
- Nelson, S.L., Riggleman Turk And Nelson
- Depository Date
- 30 Sep 1997
- Box
- 268
- Type
- TRANSCRIPT
- UCSF Legacy ID
- aqt30a00
Document Images
- - - - . . ... ;c~ .._..-. . .._. . ~ .... ia_'..~._
~
Kourt, R.E., and Coggin, J.H. Radiation sof Embryonal and SV40 Transformed Hamster Ceils
in Cutture. Proc. Soc. E~. Blol. Mld., J2$RsBi~,1988.
Kourl, R.E., Lubet, R.AA and Brovvn D.C?. In Vibro Cellular Uptake of Benzo(a)pyrene Measured by a
MaoAuorome~6rtc Tectn~que. Proc. toc. E)q. Blol. Med., LV:10Ci8-1044,1971.
Miller, O.J., MHec, D.A., Koud, R.E., Aiderdloe, P.W., V.Q., Grewal, M.S., and Hutbn, J.J.
ideMtffcatbn of
the Mouse'~ by Q~~inacrlne Fluorescence and Tentative Assignment of Seven Unkage Groups.
Proc. t~le~. ~ 1530,1971.
Kourl, R.E., MIAer, D.A., Mller O.J., Dev, V.G., Orewal M.S., and Hutton. klentMcatlon of Quhacrine
IFluoresoone of Chroma9onre G~arryk~g Mouse Lk4cage broup 1 in tfie Gattanaoh Transfocatbn. )
Genetios 1Q:129-132,1971.
MiNer, DA, Kourl, R.E., Dew , V.G. Grewal, M.B., Hutton JJ ., and Mi~er, 0.J. Assignment of Four
Unkage aroupe to Chromoeorr~e In ~ and a G~
bQenetlc Mett~od tor Locating Thek
~
~ Ends. Proc. Ne~t. Acad. Sd ,1707,19 1.
Dev, V.G., Grewal, M.S., Miller, D.A., Kourl, R.E., Hutton, J.J., and M(Aer, O.J. The Quinacrine ~
Fluoresoenoa Kar~~C
~ and Demonstratbn of Strain D
t~ferenoes In Secondary
~~~
,
Conabfctbns. CYib .438-451,1971.
M0ler, O.J., MRbr, OJ1., Kouri, R.E., Dev, V.G., Grewal, M.S., and Hutton, J.J. Assignment of Unkage
Groups VilI and X to Chromosomes In Musculus and Identification of ihe Cen
tromertc End of Unkape
,
Group 1. Cylbgenetoe, JQ:452-484,19 1.
i
Kourt, R.E., Lubet, RA, and Brown, D.Q. QuanUtatbn of i Hyd rocarbon Hydroxylase AcUvfty In
hxtvfdual Hamsiber Fetal CeNs In Vitro. J. Natl. Canoer Inst., 9W-1005,1972.
Thomas P.E., Kourt, R.E., and Hutton, J.J. The Genetics of ArytHyd n~carbon Hydroxylase Induction In
1t A§tnpte Gene Differenoe Between C57BU8J and DBA~aJ. Bloct*mlca! Genetics, fi:157-188,
MiMer, D.A., Aldenfioe, P.W., Kouri, R.E., Dev, V.G., Grewai, M.B., Mi1er, O.J.; and Hutbn, J.J.
Quktacrirre Fluorescent Chromosome Analyab of the Snell Transbcatlon in the Mouse. Genetics
1Z:6363A,1972. The Transio~m~at W.F., anand d C~hrorrioeorr~al ChanQes In Hams~eretall-Cetis.
Genetjcs, Z4~~1~ ~ 9~3.a~)
Kouri, R.E., Salerno, R.A., and Whltmire, C.E. Relationships Between Aryl Hydrocarbon Hydro,cyt~,se
Induclbility and ~ to (,'hemlcaMyInduosd Subcutaneous Sarcomas In Varbus Straktis of Mbe. J.
Natl. Canoer bat. QQ28"@9,1973.
Nebert, D.W., Benecxct, W.F., and Kourt, R.E. Aromatic Hydrocarbon Produced Tumorfgenesis and the
Genetic Dtfterenoes In ,ryl Hyrr~ocarbon Hydroacytase IN: P.O.P. Ts'o and JA. DlPaob (eds.),
Chemical
Cardnogenee s, Part A,All~ar~o91-Deldcer, New Y rk, pp. 271-288,1974
Kouri, R.E., Ratrie, H., and Whlt,mire, C.E. Evidence tor Genetic Retationship Between
3-Methyctroianttxene-Induoed 8ubcutaneous Tumor and InducblNty of Aryl }ty~drocarbon~ Ffi b
xylase.
J. Natl. Canosr kat. A1:191-200,1973.
Lubet, R.A., Brown, D.Q., and Koud, R.E. The Role of 3-0H-8enr.o(a)pyrene In
MedfaftBenzo(a)pyrene-Induoed G~rbbxidty and TransiOrmatbn in Ceri Culture. Res. Comm. in Chem.
Path.
and Pharm., flV2t}-942, 1 739
U~d ~uoe .E.Suboutaneous~Sarcorna$kelntC. J..Car~oer,12:7~7208197~4~ to 3-Metttyichotartlhrene-
Kour1, R.E., Kbter, R., and Zirrmerman, E.M. Hydrocarbon Metaboitzhp Acttvity of Varbus MarrxnaUan
CeNs in Cula". In VIfro,1Q:18-25, 1974.
kourlnlarnart.n.t 410-631-OM 41G-6S1-0f2d(FAX)
)
,-)
CTR MN 043GG2

H+xnen, RLy~'~tx~x.~yeeHCuAlhj~ ~ 2,8,7~,8~- achb~rodbOenWzo-p db~Sder, ;i:1585-Ind 5~ n!n
1974.
Kouri, R.E., Demobe, C.F., and Whltmke, C.E. The SIBnMfcanoe of fhe Hydrocarbon Hydroxyiase
IN: E. Kerbe and
~ (e~ Ine imennl ~ng Cari S, a fV~Raspi Yor~k, ^4.
J.F. Park ds.), a Exp s~ a0 New PP
Demol9e, C.F., Kourt, R.E., and Wh#trNre, C.E. CeM-Medlated ImnwNty Affer Intratrect" Exposure b 3-
; Mett ene and lta Relertj.onahip b Tumor Transplant Qnowlh in C3H/f Mai Mioe. IN: E. Karbe and
J.K. ark (eds.) ExPerimerrtal Lung Cancer, Sprtnper-Verlep, NewYork, pp. 72,1974.
WhffmMe, C.E., Demolse, C.F., and Kouri, R.E. The Role of the Host In the Development of In Vftro
Models br Carolnogenesfs Studies. IN: E. Karbe and J.F. Park (eds.), ExPertmentsl Lung Cancer,
Sprinper-Vertep, NewYork, pp. 20,1974.
Koud 3 , E.la~ntfx~ene In'Aa~E~yo G~eKit~ F~r~ wM ,uine Le~ulcemla Vkus~. Can.er~Res.Pe of
143, 1976.
eenedict, W.F., Rudcer, M., Mnrk, C., and Ko~xt, R.E. Correlation Betw~een the Balance of Specific
Chromosomes and the Expreasbn of MaNnancy In Hamster CeNa. J. Natl. Cancer Inst., ¢d:157-162,
1976. -0
Kourl, R.E., Kurtz, S., Price., and Benedfct, W.F. Studiee of the Ara-C-kxfuoed Transformatbn of
Hamster and Rat CeNs In Culture. Cancer Res., 352413-2419,1975. '
Benedict 8.moke Cnde~ C, anoeAr~ReKs~u, 857-8~,19n7b T~~n of Mouse CeMs by
C
Kourl, R.E., Rude, T., Thomss, P.E., and Whitnke, C.E. Sbudbs onpuImpnaryAcytNydrooarbon
HyOroxytase AcUvlty In Inbred Strains of Mice. Chem. 13101. Ineerlctlons, yAZ7-331, 1976.
Kourl, R.E. Relafficnshlps Between Levels of Aryl Hydrocarbon ydroxytaae AcofMbe IN: lfirtty and
Susoepdbitity
of 3-Methybt~tanthrene and Benr~o(~ ICenoers In kt~xed S~reins Fredesrtt~al
& Jones (eds.), Po~muc~ear ~IromaScpicarbons: Chemistry, Metabolisrn and Carolnogenesis,
Raven Press, New York, pp. 139-151, 976.
Nebert, D.W., Felton, J.S., Kourl, R.E., and Boobis, A.R. t3enertic Differences In the Bindi
Symp. on the
Dea) e~nd Prevention o ~ f C noer, IMa~roel-D~ek~ker,iNe wYoric,~pp~1~ 197 13th Intl~ of
~taction
Burke, M.D., Mayer, R.T., and Kourl, R.E. 3-Methychotanthrene-induoed Monooxygenase (O-
Deettrytatbn) Acttvtty of Human Lymphocytes. Cancer Res., $Z:480,1977.
, R.A., Imdum, R.L, and Kour1, R.E. NADH-G~rlochnome 0 Reductase Actlvfty in Cultured Human
x.'Ybes: Slrnflaft b the Liver Miorosomal NAD~-cvbdwome >z Enzmne System. Arch. 6bct*m.
=:119,1976. -
Kourl, R.E., Imbium, R.L., and Prough, R.A. Measurements of Aryt rocarbon Hydroxylase and
H.ENleberM~PCroCy~3 d Ir~ttl. Synip~De6eend MP v~entbn C~anoerHumMeroLel~Deldc~~NewN:
York, pp. 510,1977.
Nebert, D.W., Booble, A.R., Yagi, H., Jerfna, D.M., end Koud, R.E. Genetic Differences In
a)pyrene N~~~iogenlc rndex In Vitro and In the Mouse --Cybohrome P-450-Mediated
Benzo a)pyrene wlfte Blndin8 to DNA In Vitro. IN: D.J. Jallow, J.J. Kocels, R. Snyder, and H.
Vainio (eds.), Biological Reactlve InbermedtaM1es, Plerxxn Press, New York,1977.
Nebert, D.W., Febbn, J.S., Kouri, R.E., and Boobis, A.R. (3eneflc Differences In Blndhp of
~~and~Preventjon o~f Cbar oarA, IMdr~oei Deidaer,INewl(or~c, pp.l~0ed.)~roc. 23rd fnti. Symp. on the
kourlr.Oateart.not 416-651-9M 410-611-UZd(FAX)
i..x f R i f N ~"'~'..'f' 3~'.~ ~"°..~ 3

t
Kourl, R.E. and Nebert, D.W. Genetic ulatbn of Su9oeptiblflty to P*yc.yd{c Hydrocarbon-Indioed
Tumors In the Mouse. IN: HH. Hlatt, J.D.1Natson, and J.A. Wtnsten (eds.), Orfgins of Human Cancer,
Cold 8pring Harbor Press, pp. 811-8;i5,1977.
Sohechtman, L.M. and Koud, R.E. Control of Ben:ro(a)pyrene-Inck,ced Mammalian Cell Cybtoxicdty,
Sobe~s (ed~s.j,aP ogr~~tn~C3ene~c to~ElselNorth Hoi{andl Pr~,NevYork, VBridge of 2. pp. 307,
19n.
; Koud, R.E., and Schechtman, LM. In Vitro Metabolic Activation Systwm IN: J. Berky and P.C. Sherrod
(eda.), In Vitro Toxicity Testln3, Franklin Inst Press, Philsdelpha,nsytvanta, pp. 423, 1978.
Nebert, D.W. /Ufas, S., Ouerrttw, T., and Kouri, R.E. The Ah l~ocxls: Genetic Regulations of the
-
MetabolizePo
Enzymes
(~ ~
389,1978.
Fi P Hydrocarbons and fhe isk of Cancer. IN: O.P. Ts'o and H.V.
Blology and Envlrorxnent, Academic Press, New York, pp. 345-
Kouri, R.E., Rude, T.H., lekar, R., Dansetba, P.M., Jerlna, D.M., Atias, S.A., Owens, I.S., and
Nebert,
D.~~ '75uba~taureous Tumors in b C~ely~'Non-respo~~aNe' aatt~ie~3->s.y Ca ~~oer~Ree~s.,
362777-2783, 1978.
Kouri, R.E., Kurtz, S., Vernon, M.L Scheolrtman, L.M., Niotalson, M. Kleb~ent, V., and Benedict,
W.F.
C-Type RNA Vkus from Hams~r G~ells Transformed In Vitro by 1-B-~-Ardbinofuranosyfcybosine. Arch.
of VirobQy, $Z241-252,1979.
Kourl, R.E., Rude, T., Whttrnke, C.E. Henry, C.J, Sass, B., Bipups, LH. Correlation of In~duoibifity
of
Aryl Hyd~ rocarbon $ H~rd%xyfe~ae~~Mth ~usoeptlbiltty to 3-Mathyfoholanlhrene-hxhjoed Lung Cancer.
Kouri, R.E., Imbkxn~, 7R-..B, 1SoenowW, R.G., Sbmimy, D.J., and IIAcKinney, C.E. Parameters
Inik,endng
the Quantltatbn of 3-lantluene Induced yIHydrooarbonHydr+oxy1~ Actlvity in Cultured
Human Lymphocytes. J. nvfron. Pathobgy & ToxboloOY, 2:1079-1088,1979.
Bnemner, T., Reddy, P., Nayer, K., and Koud, R.E. Nucfeoside Ptaeptrorylase (NP-2) of Mice.
BloohemiCAi GeneL 1$:1143-1151, 1979.
Pelkonen, 0., Booble, A.R., Levltt, R.C., Koud, R.E., and Nebert, D.W. Genetic Dttfenenoes h the
MetaboYc Actlvatbn of ap yrene In Mloe. Attempts to Con~elate Tumorioenesls wtth Binding of
Reactlv~e Intertrsdlales ~ and wUh Mkutageriesis In Vitro. Phammoobqy, j$281-293,1979.
Kourl, R.E., Brandt, K., Sosnowsld, R., Benedkkx W.F., and SoheoMman, LM. In Vitro Acttvatbn of
etee Smoke Condensstie Matarlals to the Mutapenic Forms. IN: M. Waters, S. Nesraw, J.i.
H ngh, S.S. Sandhu, and L Ctaxdon (eds.) APplicatbn of Short Term 8ioeesays In the Fractionation
and Metysls of Compiex En~k+ocxnentsl kNxturea, Environmental Protectlon Apency, Research Trtungte
Partc, Norfh Carollna, pp. 495-512, 1979.
Legalor, M., Kourl, R.E., Pannar,/1.5., , S., PtN~am, D., Ledt, R., Hefclden, J., Meagher, J.F.,
Weaver, J., Kelly, N. Mutagenic Testln~ of~12 , 979~ine, Nftroethane and Diethytamine ~~ S
Kourl, R.E., Rude, T.H., Curren, R.D., Brandt, K.R., Sosnovrski, R.G., Sofedttrnan, L.M., Benedict,
W.F.,
and Henry, C.J. BbbQlca! Aceft of Tobacco Smoke Condensate and Condensate Fractions. J.
Environ. Htth. Pemp6*oft 2JM-69, J.A., Joyner, J., Nayer, K., and Kourl, R.E. Genetics of Xenotnop~
Expression In Mioe: I.
Evk
NZBBI ~anad 129/J Sai .RJ.ro~bgy,~,~:7b8,19P 7 of In~ Virus In Crosses Invohring
Koud, R.E., Schechtrnan, LM., and Nebert, D.W. Genetic Control of Cardnopen Metabollsm. IN:
Genetic Difterenoes in Chemicaf Carcfnoqenesis. R.E. Koud, ad. CRC Press, Boca Ra1on, FbrSda, pp.
21-2$, 1960.
kourlrs0emert.net 410-631-oi26 e10-s11-MdlFAX)
)
CTR HN 043664

.,
&heChtman, LM., , C.J., and Kour1, R.E. E~e, Uptake and Distributbn of Chemical
Cardens IN: Qe~nets~ryc Dtfferenoes In Chemiced CarCk~ogen~esls. R.E. Koud, ed., CRC Press, Boca
Raton~brida, PP. 1-20, 1890.
Nayar, K., O'Ne6K, B., Koud, R.E. Inheritance of EndoQenous RNA Viruses. IN: Genetlc Dffferenoes In
Cherrtcal Cardnopeneels. R.E. Kourl, ed., CRC Press, Boca Ra1on, Florida, pp. 93-128,1880.
Kour(, R.E., Wood, A.W., Levin, W., Rude, T.H., Yaql, H., Mah H.D., end Jerina, D.W. A fs of the
Subcutaneous Card,~le~dty of Benzo(a)pyrene and 13-BaF~ Derhrativvss In C3Hlf Cum Mice. J. Nat.
; Canoer k~st, ~~617 , 1990.
Henry, C.J., Whttmfre, C.E., Lopez, A., Dansle, D.R. Avery, M.D., Curren, R.C., Ca1on, J.E, Stokely,
J.R., Hoknberg, R.W., Guerin, M.R., and Kouri R.E lR~e Doskr~etry and D~Stributlon of e~teWtale
Smoke Pa~,lales In Inbred Stratns of Mice. G~omparteon of a Large Smoke Exposure Machin.~SEM)
with a SmaK Capactty Smoke Exposure Machlne (Watbn). Hanford Syrnposkxn Richland, Louislana.
IN: Pulmonary Toxdoology of Respirabie Parfsctes, C.L. Sanders, F.T. Crosa, Q.9. Dagle, J.A.
Mahafley
(ads.), Tech. Inf. Ctr., USDOE, Springriefd, Vfrg4nla, pp.177-182,1980.
Glatt H.R., 8ctiwlnd, H., SchedTtiman, L.M., Beard, k S., Koud, R.E., Zajdela, F., Crolsy, A., Perm,
F.,
Jacquigran, P.C., and Oeach, F. Mutepenk~tyof G~ Relabed Carckagenic ~-Cardnogenic
Compounds Various MetaboRizkg and ar~et CelEs. !N: Proc. tntematbnal S~r~po~urn
of Short-Term Test Sysbems De1ec:~nQ Car~o~e~, K.H. Norpoth and R.C. Garr~er
(eds.), Sprinper-V , Berftt, pp.103-126,1984.
Cm, k~,Katy-In~du~o, edJA~Car~cer. C~ Res. R.43 4-X43~67,1980~~ Expression and Susoeptib~tty to
Curren, R., Kouri, R.E., Kim, C.M., and Sthed*nan, L.M. Mutagenic and Carcinogenic Pobncy ior
Exbracts from Diesel Related Envk+onmental Emissions: Slmukaneous Morphobgk;al Transformation and
Mutagenesis In BALBk 3T3 Celu. IN: Health Effecft of Diesel Engine Emissions: Proceedings of an
Irmamationai Symposlum, Vof. 2, W.E. Pepeft, R.M. Danner, anQN.A. Ctarke (eds.), pp. 861-873,1981.
Rasnxjssen, R.E. Boyd, C.H, Dansle, D.R., Kourl, R.E., and Henry, C.J. DNA Repifcatbn and
Unscheduled DN1 Synthesfs In Lungs of Mice Exposed b CiQarerie Smoke. Cancer Res., 412583-
2688,1981.
Curren, R.D., Koud, R.E., and Schechtman, L.M. Studies fn MetaboNc Aafvatbn of Carcinopens for Cell
Transformation and ~agenesis. IN: Mammalian CeN TrariBlormatbnby Chenkc~ IN:
Advances In EnviraiRienfal ToxbobQyl9N-3541981. Dunkel, and M. Mefilrnan (eds.). Serwrb Press,
Princeton Junction, New Jeroey, pp. 3
Henry, C.J., Caton, J.E., Smicety, J.R., Guerin, M.R., Lopez, A., Henderson, C.M., Gayle, T.,
Moneyhun, J., Whitrrdre, C.E., and Koud, R.E. ~ n and Distribution of the Total Particulate Matter
of Cigarelte Smoke in Mice Using a Large Capadfy~~Smoke Expoaure System. Toxioology and Appiled
Pherm., 5$399-409, 1981.
Kourl, R.E., McK", C.E., andHexy , T.J. Genetic Control of Breast Canoer Susoeptibft In Animals.
IN: Genetsc and Breast Cancer. H.T. Lynch, ed. Van Nostrand Reinhold Co., New York, pp.14-48,
1981:
Henry, C.J., Biilups, L.H.a~Avery, M.D., Rude, T.H., Dansle D.R.,~~pez, A., Sass, B., Wi~itmlre,
C.E.,
and Kouri, R.E. A Lurq G~toer Mode4 System Using 3-Met~yd~o~anmrene In Inbred Strains of Mice.
Cancer Res., 41:5027 -5ai2, 1991.
Kourl, R.E., ODerdorf, J., Sbrniany, D.J., and McK}rxtey, C.E. Aryi Hydrocarbon Hydroxytase
Activities
In Cryopreserved Human Lymptiocytes. Cancer Letters, JA:28-40,1961.
Curren, R.D., Kouri, R.E., Kim, C.M., and SchecMman, L.M. Mutagenesis and ls Pobency
and Mutagenesis BALBI~T3 Cetts. Er~nvift roEnmental I: nOemat. :f ~411~415,~~19p81~. ~ rnesls~r~~n
, K.C.rt~Bho~a n, B., Koud, R.E., and Henry, CJ. Syr>tt~s of Trttlum LabeMed Catectiol. J.
~m~ X1X(1)25-38, 1981.
kourlr. Asm&rt.nst 410-3,3141t2b 410-S31-ia2i( fAX)
t.x f R f f f i 043665

Hwang, KK., Sonko, 0., Danafe, D.R., Kouri, R.E., andHenry , C.J. Studies on the
Distribu8on and Caiachot fro Whole Cigarette Smoke In BqF1/Cum Female Mioe. To
ApQlied Pt~am~eoobQy, ~:40b-414, 9821
Kouri R.E., , C.E., Siomiany, D.J., Snodprass, D.R., Wray, N.P., and Md.ernore, T.L. Positive
Correlatbn Between High Mr( Hydrocarbon Hydrox~lase Acdvtt~t and Prknary Lung Canoer as
Analyzed In Cryopreserv+e~ L~m~phocy~s. Canoer Res., ~S030-5037,1982.
Henry, C.J., Hwang, K.K., Kanaoltngam, KK., and Kour1, R.E. Reoent Dev+eloprrrerrts in Inhalatbn
To Evaluatlon of Selecifed Short-Term Endpolnts Following Nose-Only' Exposure of Rodents
.
' IN: Evaluation and ReOutatbn of Chemicals. F. Homburper, ed., S. Karper,.New York, pp. 233-
242, 1
Putman, D.L, Schechtrnan, LM., Curren, R.D., and Kotxl, R.E. Evakuaibn of Mutapenic and '
Cardragenic Polenrial Usirg Multiple aenstlc Endpoints In Cultured MarrKnaHan Celfs. IN: Safety
Evaluation and Regutadfon 61 Cherhicals. F. Homburger, (ed.). 8. KarQer, Basel, pp.134-141,1982.
Kourl, R.E., Blllups, LH., Ha1(, W.C., and Henry, CJ. A Mouse L.urg Car+dnorna Model System. Proc.
of
the 12th Conferenoe on Env(rorxnental ToHoiogy, AFAMRL-TR-81-149, pp. 35-49, 1982.
Sdtiechtmen, LM., and Kourl, R.E. Corretatbns Between Mutapenesis and NeoplasUc Transtormatbn In
In Vitro 8yslsms. IN: Envfrorxnent8l Mutagens and Cardr~rre . T. Supkrnua, S. Kondo, and H.
Takebe (eds.) Un#v. Tokyo Press, Tokyo, pp. 209-218, 1882.
~
Schechtrnan, l.M., Lubet, R.A., Kouri, R.E. Stvalc, A., and Tu, A.S. Evaluation of the
Transforrnation
Assay~~ C3H 10T 12 Celts for Use In bcreer~inp Chemlcals tor Carcinogenic Potential. IN: Proc.
2nd NCVEF~AMIOSH Coliaboratfve Workstap: ProOress on Joint EnNronmental and Ooaupabonal
Cancer Studfes. H.F. Kra , I.C. Blackw~ood, and TV.B. Frease (eds.). U.S. Govt. Printing Offioe,
#381-132: ~~470,19~82.
Putman, D.L., , K.T., O'NeUI, B., Reddy-Premkumar, E., Levy, J., and Kourl, R.E. Genetics of
Xenotroplc Vkus essbn In Mice 11. Exfx bn of malor virus structural
proteins In aosses v~ohrtnq NZ&BINJ, SW J, and 12Q/J strains of mice. Proc. Soc. Exp. Bfol. Med.,
=217-221,1983.
Lubet, R.A., Comoly, G.M., Nebert, D.W., and Kouri R.E. Dbenzo (a,h)-arnhrooene-Induoed
Suba~taneo«s Tumors in Mbe--Straln
Carolrtogenesis, &$13-517,1883 Sensitivity and tthe Role of CardnoQen Metabolism.
.
Lubet, R.A., Connoly, G., Kourt, R.E., Nebert, D.W., and Blgekaw, S.W. The Biological Effects of the
Sudan Dyes: Role of the ,&b CybsoNc Receptor. Bbchem. Pharrrtisool. 22W53-3058, 1883.
Kouri, R.E., Connoly, G.M., Nebert, D.W., and Lubet, R.A. Genetic Linlcafle Between Su iUty b
DiberuaMt~raoene-k~duoed Subcataneous Fibrosarooma Formation and the ~ Locus. Int. J~e~rcer
32:765-768,1883.
Lubet, R.A., Klas, E., (3aAagher, M.M. Dhiely, C., Kourt, R.E., and 8chedtman, LM. Induation of
H ~Transforrna~ ~~ ~tnale Strand Breaks In C3H t OT 12 Clone 8 Celis by PotycycNc
ky(a8rg Apents. J. Nag. Cancer Inst Z,1,1983.
Kouri, R.E., Lubet, R.A., McKkuney, C.E., CorxalN, G.M., Nebert, D.W. and Mxertare, T.L Aryl
Hydrocarbon Hydroxylase Acthrfty--"Of Mice and ?iumans'. IN: Review of Biochemksl and
Irpmunobg4c,al Mark+ers of idty Screentnp Tests. H. Miknan and S. SeN (eda.), Plenum
PuWishing Co., pp. 179-197, 1 .
Lubet, RA., Brunda, M.J., TarameMi, D., Dansle, D., Nebest, D.W., and Kouri, R.E. The Role of the
Aryl
Hydrocarbon Hydroxylase (AHH) Indudblllty in Determining Immunobxidty Induoed by the Poycydic
AromaUc In "Carcirwgenesis--A CompreFwnsMe SurvW, Raven Press, New York, Vol. 9,
pp. 25,5- , 1984.
Yang, LL, Kouri, R.E., and Cixren R.D. Xeroderma PiQmenbsum Fibroblasts are More Sensittve to
Asbestos Than are Nornned Hurrtian Fibroblasts. Carckioqeneals, 8291-294, 1984.
kourl r. dlsmut.n.t 410-681-OfZ6 410-631-Oa2alFAX)
)
)
CTRNN 04'3666

I,
Sc~ectrtrnen, L.M., Lubet, R.., Koud, R.E. Slvak, A., and Tu, J1.S. Further Evaluatbn of the
Transtormatbn ~~ C3H 10T 12 s for Use In Screening Chemicals for Cardnogenic
Potential. tlal. Proc. 3^UERA1NiOSH Collaboratlv~e Workstwp: ProQress on Jokrt Env. Canoer Studies,
Benedict, W.F., Banerjee, A., KenaBaNrgam, K.K., Dansie, D.R., Kourf R.E., and Henry C.J. Increaeed
Sister C ~ 1change In Bone Marrow Celfs of Mice Exposed b~IVhole Ciparette S~nake Mutatbn
; Levine, A.S., McKinney, C.E., Eahelberger, C.K., Kourf, R.E., Edwards, B.K., and Nebert, D.W. Aryl
rocarbon THud~ Ca~Hy R ~~'Ity~ Primary Relatives of Children with Lsukemia or Solid
Kourl, R.E., Levine, A.S., Edwards, B1.K., McLemore, T.L., Vesaeil, E.S., and Hebert, D.W. Souroe of
Inlerindtvfdual Varlatfons in ArylHydroceubonHydroxrylase In Mllopen-Actlvated Human Lymphocytes.
IN: Report #16, Qenetic Varfabllfty In Responses to Chemtcal Exposure. 0. Omenn and H.
t~~.j,. Cold Spring Harbor Laboratory Press, Cold Spring HBrbor, New York, pp. 131-144,
Kourt, R.E., Mdqm , C.E., Levkne, A.S., Edwards, B.K., VesseN, E., Nebert, D.W., and McLemore, T.L.
Variatbne In Aryl Hy~ XyIaq@Acttvtt4es h M~byen-Act*vvated Human and Non-human
Primale Lymphocybs. Tokboi~Path ]2:187-197, 1984.
Henry, C.J., Oayle T, Florant, L, Dansle, D.R., tireenspan, J. Ouerin, M Holmberg, R., Kanagalingam,
K.K., and Koud, R.. Cfxonic Inhalation Studies in NMoe: I. Fadlftlea and c~n ior Nose Cny
Exposure to Clgarette Smoke. Beltr. TbaMorach. Inlernatbnal, 9:18-31,19~: ~
Lubet, R.A., Brunda, M.J., TararnetY, D., Dansle, D., Nebert, D.W., and Kourl, R.E. kxducbon of
knmunoeoxfdty by Polycyci'ic Hydrocarbons: Role of the 6b LeoaW Arch. Toxdool. f$:18-24, 1984.
Hatich, O., Anderson, T., Schectrtman, LM., Lubet, R.A., Putman D.L, Kouri, R.E., Nhts, R.W.,
Camenon, J.W., S~6;etfs d~g , J.M., arid Tennant, R.W. Chem{ca1 Er~anoement of DNA Virus
Transformation
of Harnsier En~bryo: kftrtaboratory Testing of 12 Dhrerse Chemicals. Environ. Mutap. $:515-531,
1996.
Schecht~M~ man, LM., Hatch, O.a., Mderson, T., Putrnan, D.L, ICourl, R.E., Cameron. J.W., Nirr~s,
R.W.,
8pa1din8, J.W., Terx~ant, R.W., and Lubet, R.A. Analysis of the irtbsr- and Intra-Leboratory
Enhanoement of Slmlan Adenov~rus SA7 Trar~lomtiatfon ot Syrlan Hamsler Embrya
C~ 5 a
cinogenfc and Non-Cardragenic Compounds. Environ. Mu#eA. ~:498-514,1986.
Tu, A., Hallowell, W. Pallotta, W., Sivak, A., Lubet, R.A., Curren, R.D., A , M.D., Jones, C.,
Sedita,
B.., Huberman, E., ~Ternant,R., S~, J. and Kourl, R.E. An k~0erlabora~~~ory C~n of
Transforma8on in Syctan Hemate r Ceils Using Model and Coded Chemicals. Mutag.
11:77-98,1988.
Kourl, R.E., Mcl.emore, T., Jalswal, A. and Nebert, D.W. Current Cellular Assays ior Measuring
Clinical
In eectlons 1o I~ ~and XenoW~otk:sof Kalow, Qoedde, end ~ Techniquse. IN: "Ethnic Dft6erenoes
Agarwal (eds) Alan R. Llss, Inc. New
York, pp. 453-588, 1906.
, C.J. and Kourl, R.E. Chronic INhalation Studies in Mice Ii. The Eflecxs of LorQ-Term Exposure of
2R1 IQarette Smoke on BS3F1JCum Mbe. J. Natl. Canoer Inat. a220C1-212,1888.
Lubet, R.A., Nhns, R.W., Klss, E., Kouri, R.E., Putnam, D.L., and Sched*man, LM. Influence of
Various
Parameters on Benzo(a)pyrene Enhanoement of Atlenovius-SA-7 Transformatleon of Syrian Hamster
Embryo Cels. Environ. Mutag. 8M30542,1988.
Schechtrnan, L.M., Kiss, E., McCarvel, J., Nims, R., Kourl, R.E. and Lubet, R.A., A Mett~od for the
Ampliflr~,ation of Chert~lcafy-Induoed Transtormation In C3H/10f 12 Clone 8 oells: Its use as a
poterrtlal
saeening ess8y. J. Natl. Cancer Inst. jg:487-498, 1987.
Hurd, S.M. and Kourt, R.E. Patlartt A MeOad endApparatus for Mo{din8 Thin Gel Slabe Horizontally
with IntegraNy Molded Large Volume Sarnple Wells. Patent No. 4,785,541, January 3, 1989.
kourlr. Oamart.n.t 410-0.31-OZ8 410-3S1-0e2i(FAX)
CTR NN 043667

No. 4,,818 .,960. Aprll 4R E9.~Palent. Mett~od and Apparatus for Blottlr~ from Etectrophores#s Gels.
PaDant
HurC, S.M. and Kourl, R.E., Patent. Method ofHarKthg and Trarqporting a Transfer Membrane Used In
a Bbttlng Apparatus. Patent No. 4,812,216. March 14-, 1989.
.11
Lewis, M.E., Kouri, R.E., Laiorra, D., Berka, K.M., Lee, HC.`and Qaenssfen, A.E., Restriction
FraQment
Length~ ~ ph DNA anaysEs by the FBI l.aboralory Probool using a simoe hardware System. 1990.
Hurd, S. and Kourf, R.E., A Mettwf for Mokilng Thin Gel Siabs HortzotitaNy with Integraity Mo{ded
Large
Volume Sarroe Weft Patent No. 4,909,977. March 20,1990.
Lewis, M.E., Kourl, A. E., Lalorra D., 8erka K.M., Lee H.C., and t3aermlan R.E. Restrictbn Fragment
~tsm DNAnalysts by ttre FBI t~.aborabory Probool usk~ a Simple Convenler~i
~ware J. Forex4c Sd. 351188-1190,1990.
C.8.i ~Vourniskis ~J of ~.R~~ W.T., ~ Wale /lrtaly sls rbury P.a ~ Kouri R.E. A Strategy for
rtalysls AppliC., fi:151-158,1891.
Lane, M.J., Waterbury P.G., Carrol W.T., Smardon A.M., Faldasz B.D., Monte S., Huckaby C.S., Kourl
R.E.,i"., Variation in Genomic Alu Repeat Denstty and Basla for Rag-id Constructfon of Framework
Phyglc~,al Maps of Human . Ctxomosoma, M: 348-357, f892.
Ruano, 0., Lewts, M.E., and Kour1 R.E. Cyclized Primer Exlension: A Method for Simuttaneo«s DNA
Redbiabeflnp and Syntheses from Temp(ates of Unknown Sequence. Anal. Blochem. 2U:1-6, 1993.
Ruano, a. and Kouri, R., Coupte0 Amplification And Sequencing. Pa*A awarded, 1994.
Sprinkle, T., Kour1, R., Fain, P., Stoming, T., and Whitney, J. III Chromosornal Mappinq of the
Human
CNP Gene Using a Mebtlc Crossover DNA Panel, PCR, and A11ele-SpectNc Probes. Genomics. l$,; 542-
545,1 A93.
U, W., H aby, C., Kourl R., and Ruano, R., Human Genomic Characterization of a Novel Locus-
Specific Re~petrove Sequence. t3enomlcs 28297-402,1895.
Tombran-Tink, J., Mazuuk, K, Kourt, R., Chung, D., Unker, T., Chader, O., and Rodripuez, I. Cion*ng
and MoieWar Characwzatbn of the Human Gene for the Neurotropilto Serpin PEDF: Conservation,
Polymorphism and Herttabilltiyr Studies. SubcNtW,1998.
Chol, J.Y., U, W-L., Kourl, R.E., Yu, J., Kao, F-T., and Ruano, f3. Vtrtual Mapping of Acute Phase
R~sponse Fac~ or (APRF) b 17q21 based on Sequence Bbfnformarios of Mbrod4ssec.~led DNA.Genomics
a8(in Pr~
E= 8wla
'C3enetSc Dlfferenoes In Chemical Cardnopene$Is', ed., R.E. Kourl, CRC Press, Boca Raton, FL, 1984.
'Health Effects of Pyrerre and Selec.yed Analogs', Committee on Pyrene and SelecW Anabgs. D'Mston
of Mediced Sciences, National Research Academy, National Academy of Scienoe Press, 1983. ,
'The Evaluation of the Car Risk of Chemicals to Humans - Tobaooo Smoking", IARC
Monographs, Lm Franoe,1987.
'The Genetics of Mental Disease, Health and Sciences Comrnur4Catbns, Washington, D.C., 190 i.
Ws"
- kourlr.0.mart.nMt 410-611-St2d 41o-ai1-M* FAX)
)
,
r )
CTR NN 043666
