Council for Tobacco Research
Cancer Scientist's Comments on Smoking-Lung Cancer Review [Discusses Evidence Which Conflicts with the Tobacco-Smoking Theories of Lung Cancer]
Abstract
MAR
Fields
- Master ID
- Ctrmn00042811-3384
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- Author
- H And, K.
- Depository Date
- 08 Sep 1997
- Box
- 267
- Type
- PRESS RELEASE
- UCSF Legacy ID
- fpt30a00
Document Images
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TOR: TOSAOCO LNDOBTRY RSSSARCH CCAMIITPEB
lOR PMxsS* IN AM'a 01 iRIDAY, AOVI?ffiIIt 27, 1959
C/L'4LER 6CIF77TI6T'8 Wl441STg
014 6MKR0-It180 CAACER REYM
21av Zork -- Dr. C. C. Little, seieat+.lic direotor of the 'lbbaeco
Industry Researc.h Committee, today issued a commeat,oa the statement of the
Publie Eealth 6rrvice on "B:aohing aad Ttmg Cencer."
Dr. Little's comoeat folloYs:
"Tods,y, more thaa ever before, scientific evideaoe is acevmnlatta6
that ceariicts vith or fails to suyport the tobsceo"txating theories of
lnng csncer.
'YAny of these ban beea oaitted from or glossed over in the Public
Esaltb 8ervioe article and press release.
~
'Within recent matha, nev eridenee hat beaa presented that:
"l. ?Ynds that peopl.e described as the wrld's heaviest
cigarette smokers bave 1ov lcmg osacer death rates c:onpared vith people
vLo saoke less but have been long eaposed to urbaa air pollution.
'2. Sbow that dir.ct inhalation of tobacco smoke by laboratory
taimals ovsr lcmg periods of tlme naa not renilted in causing lnng cancer
in tLeae
"3. Reveale that human lung tissues uadarg,o changes, considered
anspicious by a'me, that s.re found a9ong both 7otmg and old, non-smokers
and sxkers, vkile lung tissues 'aay be perfectly normal in beary smokers.'
"4. Contirms the long-eatablished but little publieited fsct
that lung cancer occur; core frequently in people Vho hara a nedicnl history
of previous se rious lung ailments, such as tubercnlosis, paeunonis and
influeaxa, indl;ating a relationship of possible significaace.
(more)
11311722
C MI 1 4 ! I l y! 0 431 Rsl 4

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"Dsspite these recent research trends, the eonelusions set rorth in
the reviw rely almost entirely oa past reports that are no soro cooclnsire
today than when these reports vere first qdblishad. ?Iost of tbe points ars
not new but ass fsmiliar to the Aaerican public beosuss tbey ver first
aCvsnced some years sgo in statistica7l stodies that admitted]y are not
supported by experimeIIEal eridence.
"Indeed, the eonelusions stated vill not seea to aaay Vho reed thea
care2ul.i,y to be esteblisbed even by ths rn11 context of the reviw as
publisbad.
'Tor instaace, the re.iw clearly states that sxperimsatal evidence
does not support the theocies.
"Fhe reviev recognises that lung cancer stllicts nonsmokr.rs, aad
therefore can't alt be bSamed on smoking. It concedes the stiL1-to be
eTalaated role of air pollutants sad occupational axposnzss. It s4alts
differences in lung eancer incidence rates that carsot be erpls.ined by the
snoking tbeory.
'*2Ia conclusions place coxplete rslisme on opinions gublisbed by
those who are ooemnitted to the tbeory tLat tobsceo has the principal
ceUSative role in lung cancer.
'Toar in¢portsnt sreaa of research fiadings that ars givsn little or
no weight in eonsideration of the problem are the rollvwingt
'7. The British Hedical Jotraal in Octobar published detsiled
svidenee suggssting that sir pallutioa, nat cigarette smoking, is a =jor
factor in lung eanoer in South Africa. White nalss there bare long been
ROm4 the havi*nt Rtsa.+1.+- .wnr.... t- .U., ......%a - .J. _ . .. -
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"IaterestinBly, these findings are similer to those reported in
195b trom Hev Zea7.aad, %&ere lung cancer death ratea vars also associatad
vith prerious residence in industrial cities rather than vith the rate or
cigerette saoldn8.
'2. Rwterocs expesinents both hers and abroad exposing aXperlaauCal
aais:als to direct inhalation of tobaeco ea+oYe have bsan reported. lfone of
these has yro3ucad rvid.ace of ltmg cancer oansed iaahase animaI .a by the
ssoke.
"Ia Jay, the 8ritish L0ire Cancer Csapatgn reported that five
Tears of sueh ucperiasats produced 'striking negative results' by not causing
lung cancers in the anim.ls. The significance of snch inhalatioa eapariments
compared vith aaSmal sYin-paintiag tests is, of ceurae, obrioas.
"3. The reviev refers to one et114V concerning certain eell changes
fouad in htiaan lung.s. 9ut other izrves'tigators don't n4pcrt thate olairs.
Tbe lstter reDort such chaages in the langs of yama people aaR old people
vho have never ssao7ud aad they find no such changes in mxy old people vith
a long histoc7 of asoYirg.
poe such rece=t sttAjr :rported that the lung liaing 'miy be
perfectly oo:aal in heaTy srakars, wnn in sua vbo hare smclced lron a3olssceace
aad reached a coanmption oi 40 cigarettes a day.'
`Such findings aske it obvious that the oell changes under stuQ7
are neither a sole result of isating - since they are found in aon-smoters --
not a necessazy result of sao:aira -- since they are not foun3 in man,y heavy
smokers.
"4. An incraasin3 nusber of scientists are nov eoafirmitfg a close relationship bctveen tba
incidence of lung cancer and a aedieal history of
previous lung s.llments eucb as peeumonia, tubercalosis, inflnensa and bronchitis. ~Y
One nev study found a very high co.-zelation betveen a positive tuberculin
reaction and lung cancer, vith a relatively lover rate of cigarette sa*ing
=ong the lung cancer patients.
(scre )
11311724
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t~r f f"ti ~ i N ti.A ""'f' 3i, r+~ 6

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^Tb+se :rportr a:e onlr nov ccodaa to scieatitic aasation as a
rerult of the i.acreaasa recesrch iato the yrobl.ezt of itms camcer in recent
yeara.
'They shav cleariy that vs are only at the thresholQ of nrAarstrading
ths bree!!th aad !l.epth of the lung ceacer yrrobl,em."
(lfat.o AttsnLeb sr. fev of the scientific citatioas oa v`-iah tbe above
. foar points .rs Dssed.)
i
11311725
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