Council for Tobacco Research
Bio Research Consultants, Inc. Consultants to the Tobacco Industry Since 1959, Is Now Offering A New Technology-- A Fresh Smoke Inhalation Method [Offering Smoke Inhalation Studies to Tobacco Industry]
Fields
- Master ID
- Ctrmn00041967-2810
Related Documents:- CTRMN041967-2114 Deposition of Freddy Homburger, M.D. [Deposition of Homburger in the Matter of Broin]
- CTRMN042115-2200 Deposition of Freddy Homburger, M.D. [Deposition of Homburger in the Matter of Broin]
- CTRMN042201-2213 Chronology of Events [Letters and Chronology Outline Dispute Over Publishing Research on Cigarette Smoke and Hamsters]
- CTRMN042214-2228 Inhalation Carcinogenesis Experimental Investigations on the Effect of Cigarette Smoke Inhalation on Small Laboratory Animals [St Effects of Long-Term Exposure to Tobacco Smoke on Small Animals]
- CTRMN042229-2248 [Cigarette Smoke Inhalation Studies in Inbred Syrian Hamsters]
- CTRMN042249-2251 [Comments and Suggestions on Study Titled Cigarette Smoke Inhalation Studies in Inbred Syrian Hamsters]
- CTRMN042252-2269 Strain Differences in the Response of Inbred Syrian Hamsters to Cigarette Smoke Inhalation Journal of the National Cancer Institute, Vol. 53 [St Cigarette Smoke Caused More Cancer in One Strain of Hamsters Than Another]
- CTRMN042270-2294 Progress Report for the Current Contract Period and Renewal Application (with Budget) of the Project Entitled the Determination of the Usefulness of the Golden Syrian Hamster As Model Animal for Inhalation Studies [Cigarette Smoke Inhalation Caused Macrophages in Some Hamsters' Lungs and Reduced Weight Gain But Did Not Affect Mortality]
- CTRMN042295-2298 [Summary of Meeting on Status of Research]
- CTRMN042299-2304 [Draft of Contract for Inhalation Studies in Syrian Hamsters]
- CTRMN042305-2308 [Comments From Counsel About Contract Form]
- CTRMN042309-2316 [Agreements Between Ctr and Bioresearch Institute and Bioresearch Consultants]
- CTRMN042317-2345 Skin Painting Studies in Syrian Hamsters Skin Painting Techniques and in Vivo Carcinogenesis Bioassays Progress in Experimental Tumor Research, Vol. 26 [St Skin Painting Caused Tumors in Hamsters More Frequently Than in Mice]
- CTRMN042346-2350 Pulmonary Eistopathology of Hamsters Exposed to Smoke [Histopathological Findings of Study of Hamsters Exposed to Cigarette Smoke]
- CTRMN042351-2403 [Expanded Study of Mouse Skin Exposure to Whole Fresh Smoke Condensate Compared to Skin Painting Final Report]
- CTRMN042404-2405 [Ctr Delaying Approval for Continuation of Smoke Inhalation Studies Seeks Guidance in Procuring Funding]
- CTRMN042407-2422 [Results and Methods of Bioresearch Consultants' Studies Are Property of Ctr Inhalation Studies with Cigarette Smoke]
- CTRMN042423-2423 [Disputes Claim That His Actions Are Breach of Contract]
- CTRMN042424-2424 [Suggests Meeting with Hockett and Jacob Before Presenting Paper]
- CTRMN042425-2425 [Summarizes Conversation Publish Scientific Data But Clarify Source of Interpretations and Ownership of Patents]
- CTRMN042426-2426 [Abandon Bulletin on Inhalation Studies with Cigarette Smoke Delay Involving American Society for Testing Materials One Year]
- CTRMN042427-2427 [Abandon Bulletin on Inhalation Studies with Cigarette Smoke Delay Involving American Society for Testing Materials One Year]
- CTRMN042428-2473 [Manuscript on Strain Differences in the Response of Inbred Syrian Hamsters to Cigarette Smoke Inhalation Submitted for Approval to Publish]
- CTRMN042474-2552 "Final Report on Contract C-191 A Project Entitled "the Determination of the Usefulness of the Syrian Golden Hamster As Model Animal for Inhalation Studies"" [75 Weeks' Exposure to Cigarette Smoke Produced Various Results in Hamsters, Including Macrophages in the Lungs, Increased Heart and Lung Weights, and Decrease in Body Weight]
- CTRMN042553-2553 [Encloses Assignment for Patent No. 3528435 Seeks Direction in Withdrawing Paper at Federation Meeting]
- CTRMN042554-2554 Sugar in Tobacco [Deplores Speculation in Tobacco Controversy Reports on Successful Studies of Smoke Inhalation with Hamsters]
- CTRMN042555A-2555 Fluoride Ion Excretion After Inhalation of Several Fluoroethylene Derivatives [St Exposing Rats to Atmospheres of Fluorinated Ethylene Compounds Increased Urinary Excretion of Fluoride Ions]
- CTRMN042555B-2555 Pulmonary Histopathology of Hamsters Exposed to Smoke [St Exposing Hamsters to Cigarette Smoke Resulted in Effects on Pulmonary System]
- CTRMN042555C-2555 Response of Rats to Pyrolysis Products of Fluorinated Polymers [St Physiological Responses of Rats to Pyrolysis Products Included Diuresis]
- CTRMN042556A-2556 Tumor-Associated Alkyldialacylglycerols (Adag) and Other Lipids in the Thymus During Irradiation-Induced Leukemogenesis Pathology 2202 [St Analysis of Tumor-Associated and Other Lipids in Mice Following Radiation Doses]
- CTRMN042556B-2556 the Endocrine Role of Dietary Lipids in Mammary Tumor Formation Pathology 2203 [St Mice Fed Lipids to Determine Effect on Tumor Development]
- CTRMN042556C-2556 Effects of Altered Dietary Fat Intake on Serum Prolactin Titer Pathology 2204 [St High Fat Diet in Rats Resulted in Increased Serum Prolactin Levels]
- CTRMN042556D-2556 Altered Incorporation of 3h-Thymidine in Hamster Tracheal Epithelium Caused by Respiratory Carcinogens Pathology 2205 [St Hamster Research Suggests That Dna Damaged by Respiratory Carcinogens in Vitro Can Be Repaired]
- CTRMN042556E-2556 Histopathology of Respiratory System of Bio 15.16 Hamsters Chronically Exposed to Cigarette Smoke [St Hamsters Exposed to Smoke Had More Pathological Lesions in Their Larynxes]
- CTRMN042556F-2556 Peritoneal Mesothelioma Pathology 2207 [St Study of Patients with Symptoms of Peritoneal Mesothelioma]
- CTRMN042557-2573 Strain Differences in the Response of Inbred Syrian Hamsters to Cigarette Smoke Inhalation Journal of the National Cancer Institute, Vol. 53, No. 4 [St Smoke Exposure Resulted in Reduced Body Weight, Enlarged Heart and Lungs, Hyperplastic or Neoplastic Changes in the Larynx, and Microinvasive Cancer in Hamsters]
- CTRMN042574-2591 Experimental Lung Cancer Carcinogenesis and Bioassays Cigarette Smoke Inhalation Studies in Inbred Syrian Hamsters [St Smoke Inhalation Produced Hyperplastic Changes in Hamster Larynxes and Decreased Body Weight, But Did Not Affect Mortality Strain Differences Were Pronounced]
- CTRMN042592-2599 ""Smokers' Larynx" and Carcinoma of the Larynx in Syrian Hamsters Exposed to Cigarette Smoke" [St Smoke Exposure Resulted in Cancer of the Larynx and Severe Epithelial Changes in Hamsters]
- CTRMN042600-2603 Homotransplantation of Larynxes of Cigarette Smoke-Exposed Syrian Hamsters (38760) Proceedings of the Society for Experimental Biology and Medicine, Vol. 149 [St Sections of Hamster Larynxes Were Transplanted Into Cheek Pouches of Other Hamsters Hyperplasia Caused by Cigarette Smoke Persisted Up to One Year Without Further Exposure to Smoke]
- CTRMN042604-2626 Differentiations in Cigarettes Off Materials Other Than Tobacco Medicine Et Hygiene, No. 1216 [St Smoke From Cigarettes Made From Cytrel Contains Less Tar Than Tobacco Smoke and No Nicotine]
- CTRMN042627-2670 Advances in Modern Toxicology New Concepts in Safety Evaluation [St Syrian Hamsters Are A Valuable Option for Animal Experiments]
- CTRMN042671A-2673 Detection of Chemical Mutagens Using Concentration Gradient Plates: Observations on Results with 414 Compounds Toxicology and Applied Pharmacology, Vol. 45 [St Discovery of Chemical Mutagens]
- CTRMN042671B-2673 Dominant Lethal Studies in Rats of Five Hair Die Components: 2 Nitro P Phenylenediamine, 4 Nitro O Phenylenediamine, M Phenylenediamine, 2.4 Diaminoanisoic Sulfate, and 2.5 Diaminoanisoic Sulfate Toxicology and Applied Pharmacology, No. 45 [St Weak Lethality Results From Exposure of Rats to Hair Die Components]
- CTRMN042671C-2673 Motor Oil Antagonism of the Effects of So2 on Pulmonary Function in the Guinea Pig Toxicology and Applied Pharmacology No. 45 [St Motor Oils Reduced Irritancy of So2]
- CTRMN042671D-2673 Cigarette Smoke Inhalation Studies in Inbred Syrian Hamsters. I: Methods and Dosimetry Toxicology and Applied Pharmacology Vol. 45 [St Hamsters Exposed to Tobacco and Cytrel Cigarette Smoke and Results Noted]
- CTRMN042671E-2673 Cigarette Smoke Inhalation Studies in Inbred Syrian Hamsters. II: Histopathological Lesions in the Respiratory Tract Toxicology and Applied Pharmacology, Vol. 45 [St Tobacco Smoke Resulted in Larynx Problems Including Invasive Carcinoma Cytrel Smoke Resulted in Much Less Damage]
- CTRMN042671F-2673 Pulmonary Pathology in Rats Exposed to Marijuana Smoke for One Year Toxicology and Applied Pharmacology, Vol. 45 [St Rats Exposed to Marijuana Smoke Developed Focal Pneumonitis in Proportion to Dosage]
- CTRMN042671G-2673 Studies on the Pulmonary Uptake of Paraquat Toxicology and Applied Pharmacology, Vol. 45 [St Distribution of Paraquat in Rat Lungs Was Not Uniform]
- CTRMN042674-2749 Chemical Carcinogenesis in Syrian Hamsters: A Review (Through 1976) Progress in Experimental Tumor Research, Vol. 23 [St Hamsters Are Useful Experimental Animals for A Variety of Carcinogenesis Studies]
- CTRMN042750-2764 Cigarette Smoke Inhalation Studies in Inbred Syrian Golden Hamsters Journal of the National Cancer Institute, Vol. 65, No. 3 [St Cancer Was Developed in Hamsters Exposed to Tobacco Smoke Cancer Rates Were Proportional to Smoke Concentration and Tobacco/Cytrel Ratio in Cigarettes]
- CTRMN042765-2769 Cigarette Smoke-Induced Cancer of the Larynx in Hamsters (Cinch): A Method to Assay the Carcinogenicity of Cigarette Smoke Progress in Experimental Tumor Research, Vol. 24 [St Hamster Experiments Are Valid Assay of Tobacco Smoke Carcinogenesis]
- CTRMN042770-2772 in Vivo Carcinogenesis Testing Toxicologic Pathology, Vol. 7, No. 1 [St Smoke-Inhalation Experiments with Hamsters Are Quantitative Assay Method for Relative Carcinogenicity of Cigarette Smokes]
- CTRMN042773-2782 Carcinogenesis in the Upper Aerodigestive Tract [St Carcinogens Such As Tobacco Applied to Mucous Membranes Result in Multiple Tumors Which Are Difficult to Treat]
- CTRMN042783-2787 Subchronic Cigarette Smoke Inhalation Studies in Inbred Syrian Golden Hamsters That Develop Laryngeal Carcinoma Upon Chronic Exposure Journal of the National Cancer Institute, Vol 71, No. 3 [St Smoke From All-Tobacco Cigarettes Caused More Respiratory and Larynx Problems Than From Cellulose-Derived Tobacco Supplement Cigarettes]
- CTRMN042788-2796 A New First-Generation Hybrid Syrian Hamster, Bio F1d Alexander for in Vivo Carcinogenesis Bioassay, As A Third Species or to Replace the Mouse Surv. Synth. Path. Res., Vol. 7 [St This Strain of Hamster Is Perhaps the Best Suited for Cancer Experiments]
- CTRMN042797-2800 [Comments on Slides From Effects of Smoke on Upper Respiratory Tract]
- CTRMN042801-2802 [Conditions for Approval of Publishing Findings]
- CTRMN042803-2810 [Disputing Ctr's Decision to Discontinue Research Chronology of Research-Related Events]
- Author
- Bioresearch Consultants
- Tobacco Reporter
- Depository Date
- 08 Sep 1997
- Box
- 267
- Type
- ADVERTISEMENT
- UCSF Legacy ID
- cnt30a00
Document Images
3
n
V..
s=
a
consultants to thC t6bacrP
Industry since 1939, ls now
offering v n.w technology-
a fresh smoke inJ+olatien meth.r
cuirq inbr.d..r11-deftnad ElO AorosttR
vrith ithr our own pote++t+ed n+ada+o
or the snachine of your chio..
aio-Research's eJBarette smoking
inhalatiosn studi.s will -
p7a ycv izforrretion. vr+olitainable
any other wr, n len.g.".rec .r
shoryter+n .#eets af unoks upern
the respiratory tyrttR+ end heart. and
tell you more about tobacco
unoke than on'y other
laboratory method for:
prdvefien me+difieatian
qval0y mn+r.l
6roftd tdrnparlaens
f$!r voluations
f....r 1~.d..isf 11rii.rLr v
d.seUd ird.rw.+%.w .b.t w.
COMHfN.q 147fAf WTSt .r /ftraft
8l0-RESEARCB MliSIllQM K
~ ome..~a+ aw.,. F ars aok w at41
rs.~e missa~a
C~a
0
A 1
CROSS coU~MAINE
Giriw..i rr... p,."di,.t jrs.
lnea a6 1oio.2 tl>s OLi Ddi Ws:cboztse Aaacariea ia
OPpaiDf tb. eoUesemeM
DeJatoews ceeetarion is Mrne
eas ~. iss'c sazdp
at Noash Ctroli+sa Sass Uoi.eoitr. Tlv uudt slara vuc
Old aa[ 3,Cs1.11 . Beic pv.en wasLd teod a b.e mre aad
mocs assare sa e!u big plsaaaap"~ f+mss %a.n eas
Is also sbo.a tbst Nactb Csedlea sod virj+aia tsrmaa
v besp m i.as. 4rir s.mooaa o! eorea6e eo Smth
aa aod `Georpa lI dse kdenJ wMcam rerms Cho
aaaaFs ef aflnoama saon sav,e lioea.
Dc. Dale M. Sacrs. the psQfsoor whe asoierc:ed
de smdy. mid thac as>d- cb. preene ks. sad csssuia
peoan+m 406 e,oaasp aee a a sepsssst sssaclCSc for
m5.ao toeat M a s.csla, seaaA ratsi smp srq fma
l.a thaa fie a.aa pr pomd in ths Oid aelt eo mors
clsaa ]D oras a poawd ss ch. Bordes SNt
Z3e aeiacien stims isom ififfesmcss ia !oo! Yisids& farm
.rape rss aod nea4rm jeb opporsona+a be ssid. bectase
of the VUiitioai be aoododo tfsu %be leas aad marfcr of
qoass aana a+uaey aad sav L'ne .eWd capu,oe waall
dfie,ieaey of ptodootiob
`Rmts1 lata .aold eaeu tleaes o tlst sam. Ie+sJ in sSl
aran,' Hoora saiL "Lb4 ooacl eosc foc produdo,p die ae+~
wl1 dsep bt so a.vspc of abevr ar ®t pet peOSb
H+orv's s,Jr sbe.e tbac veh aWocm, wid Ls.m had
cst feca.rim tlhet ssda 196t rmdieian.:
OY 8alr. Gse.ees .0.11 da.e lasod oZU 91 milliea
jnada e,t 69 ps: cmr of st+.ii )ws eo jroe ~s ia .dec bela
h[Jdd1. Sdt: Oto.ess .vald ha.e Lssi ent 32
ral&" -som:w ar 31 per wac of st<ar l,ase mPa.cu in
altes lwda
Iatsae SelL: Gtaats r+ald ba.e lesssd aa dJl
eimaJ 60 saillto4 poosds of mr.ess tron otba b:a sieb
.ou1d ha.e ban dw .qai.alicat ei Gd per es.r of tlu Lu.
lvoM foc the We
border $da Grseea .reafd baw '.ar.d sn addi
oa.al 63 milli- poonis oF mbeu= it= ecbet b.ia, aiek
.ould b.. bee. i. equi.elene 0166 pes mc of dke bsae
;oors fer s~w b.k
Vaia tiese modly-te+os 16s r.nal :,u (oe yoaeas qWas
.wN law b..o sbess 13.3 ==I rs poond asOOaOout
volik Cii71im Ntb06#b opPde>i j8 plSOG'jfia m aa a
taadei baxat PMO'aas. hsa= IIRaoc csasa.n af tbe
~aau.ap..do l4a.CAu.d Tob.err ki:iodar CaMMic~
b.i;r.. Hooa's Eiadia~ are *V=d1 cacco-W
v'ftis tb. aup.off in ptioe e%tse to rsa2z; "tb.one
Wwold be leas .ulai' am.oi O!d Sak fsemsa w
loase so ebnw p.o*li^ 3sidM ha sa4 ~ hs"
fasmora +sowia=_ 1d aad SO .a. .f mb.cra oa la.od
.haa mec4aaJ+al eanaseea asa be uad to a hifb
te..lotdfbdosacy~
~shii4 of ab.aa ~.~6 c i~~ ~ ~d
s Wss4oal
opp~ss ie fas c~ac tauso. He doeea, tie.e~a. c~rt eb- shift
mid 6. as ssddea ot damaoe ss sesae }ss. E.aed. Q
tngvo~ry issd.rs .r.ak evl
aq.itest .nd of 6artsr program
21+. US Depcves e! APiM%isr: s r+.csnt sammaian
e# a barsa p~ee~am mo}rx~nt o oobess ~or~ hu
kea~t aio .f sa4Mstt fraoi Zb. Sos!'s Lpeau:.d lmf
io~nsa~ "We "dlT syed da peaxua to sos oac os.
6.rm .lte+si .ad .e are Lepia= v~ a taae~e~' Jasesh
LmP'u6ara, psaidw of Tob- Asro.c.L sLii lsc monckL
WiIIluna sere ortsaissdsm p*<ras ~e, ss;m a tse~ i~:
m~b.ao morW snsr~sQ ord aboac , S2D0 r'k^ .orb aE
'"..~ :~G- .Y~~
EXHIBtT N0.1..~
~3~/
TaQSaA Raver'Cat f Jun. 1l77
iC7AL ? . 22
~~f`~. i ff'~ 0"'~"f'4..,l4:~
