Council for Tobacco Research
Deposition of Freddy Homburger, M.D. [Deposition of Homburger in the Matter of Broin]
Fields
- Master ID
- Ctrmn00041967-2810
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- Author
- Bohan, A.H.
- Homburger, F.
- Depository Date
- 08 Sep 1997
- Box
- 267
- Type
- TRANSCRIPT
- UCSF Legacy ID
- mmt30a00
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130
other animals, but I was not aware of the details.
Q. Let me ask you to take a look at Exhibit 9,
Dr. Homburger. That's the April 22, 1974,
memorandu m from Mr. Zahn. Do you recall that? You
testified about it a few minutes go.
A. Yes, Mr. Edell gave me.
Q. I just want to make sure I'm clear. Is it
your testimony that Mr. Zahn was wrong when he
stated that Ms. Graves called you back to sa y that
she had called off your press conference?
n
d MS. SCHNEIDER: Objection. Asked a nd
a
swere
.
A.
Yes, that's definitely not
correct.
Q. Let me ask you to take a look at th e
portion o n Page 1 of that memorandum which M r.
Randles a lso sho wed to you, and the last -- the
second pa ragraph , when it says that, "He," and
that's you, Dr. Homburger, "was to have a news
release w ith him and was to tell the press that the
tobacco i ndustry was attempting to suppress
important scientific information about the harmful
effects o f s moki ng. He was going to point
specifica lly at CTR. " Is that also wrong?
A. Yes.
DORIS 0. WONG ASSOCIATES
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Q. Is there anything in this memorandum that
you know is correct?
A. No.
Q. It may be all wrong, as far as you know?
A. I certainly didn't see it that way. I was
just going to a room where there was a press
conference supposed to be held, and nobody was
there.
Q. And the purpose of your press conference
was to report your scientific results?
A. Yes.
Q. And you did report your scientific results
at that meeting?
A. I did that in the talk I gave before the
press conference was to be held.
Q. And you showed slides at that meeting?
A. I showed slides.
Q. And --
A. It was the usual ten-minute paper.
Q. And you said that you found microinvasive
carcinomas?
A. Yes.
Q. Was that the substance of what you
presented in that talk, the same as what --
DORIS O. WONG ASSOCIATES
CTR I-IN 042098

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A. Well, there was an abstract on that talk.
Q. Excuse me, Dr. Homburger, let me finish my
question if you would. Is the substance that you
presented in that talk in Atlan tic City the same as
the substance that you intended to present in th e
press conference?
MS. SCHNEIDER:
A
Y Object ion to the form.
.
es.
Q. Now, you
talked about a meeting that
occurred in Maine,
correct? in July or August of 1973,
A. Correct.
Q. And at that meeting you said Mr. Jacob made
some statements to you about the consequences of
your publishing your paper - -
A. Yes.
Q. -- correct?
A. Right.
Q. And that was the pa per that you had
intended to publish?
A. In the Journal of
t
he National Cancer
Institute.
Q. That was my questio n; why don't you let me
ask it.
DORIS 0. WONG ASSOCIATES
CTR 1"11-11 04,` 09-9

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MS. SCHNEIDER: You're asking the same
questions and covering the same ground that's
already been covered this morning.
MR. KLUGMAN: That's because I'd like to
ask another question, and it would be difficult, I'm
sure you'd have a lot of objections if I said, do
you remember your testimony this morning --
MS. SCHNEIDER: You asked him whether he
disagreed what was in it, he said that already, the
exact same question was asked. So that's why he
easily anticipates what you're asking, it''s already
been asked and answered.
MR. KLUGMAN: Are you finished, we'll get
on with the deposition?
MS. SCHNEIDER: Please ask some new
questions.
MR. KLUGMAN: You are finished?
MS. SCHNEIDER: We're waiting for you. You
know, we've taken breaks, we've been waiting. It
seems like we've just gone on and on with your
questions.
MR. KLUGMAN: This is a horrible imposition
on your time and I apologize for it. We'll muddle
along the best we can.
DORIS 0. WONG ASSOCIATES
CTR { f N 042-1 ~~ 0

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MS. SCHNEIDER: It's no imposition to me.
We took a ten-minute break, then for an hour, then
we were waiting, we were told we were waiting for
copies. Now we're asking questions about the same
areas.
MR. RANDLES: Now hold it. I've tried to
avoid wrestling with you in this deposition, but we
started off by waiting until 11 o'clock to start a
ten o'clock deposition, we took an hour for lunch,
we've been here a grand total --
MS. SCHNEIDER: You took an hour for lunch.
MR. RANDLES: Exactly. We've been here a
grand total of less than four hours for a deposition
that was scheduled all day. I think we're doing
pretty well. Why don't you go ahead, Steve.
MS. SCHNEIDER: I mean, when you have
questions, y es, we can go on with the deposition.
Let's ask so me real questions, not ones that have
been asked and answered.
MR. KLUGMAN: Should I run my questions by
you first for approval?
BY MR. KLUGMAN:
Q. Does Ms. Schneider represent you,'Dr.
Homburger?
DORIS O. WONG'ASSOCIATES
CTR. 11N 042101

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A. I beg your pardon.
Q. Is Ms. Schneider your lawyer?
A. No, I have no lawyer.
Q. The meeting that you testified among you,
Dr. Hockett and Mr. Jacob, the subject of that
meeting I think you said was the article that you
intended to publish and in fact did publish in the
Journal of the National Cancer Institute; is that
right? And they came up to Maine to see you
sometime in the summer of 1973?
A. Yes.
Q. And you in your testimony attributed some
remarks to Mr. Jacob; is that right?
A. Right.
Q. Is there any document that you're aware of
that reflects Mr. Jacob making those remarks?
A. Well, there is my testimony in the
Cipollone case.
Q. Before you testified about it in 1978 --
excuse me, let me withdraw that. Before you
testified about it in 1987 --
A. I don't believe so.
Q. -- or 1988, whenever that testimony was.
This happened during 1973?
DORIS 0. WONG ASSOCIATES
L1T R N N 0 6'-i~d . d. 0.02. >

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A. Correct.
Q. During the succeeding 15 years, is there
any piece of paper that was created that reflects
the substance of that testimony?
A. I don't think so.
Q. And you wrote letters to CTR, did you not,
during at least some of those 15 years?
A. Oh, yes.
Q. And you complained about your not receiving
further funding, did you not?
A. Say that a little louder.
Q. You received -- withdrawn, let me start
again. You complained to CTR about the fact that
you didn't receive any further funding, did you not?
A. I did, yes.
Q. And when you didn't receive any further
funding from the National Cancer Institute, you
wrote some letters complaining about that?
A. I had no previous funding from the National
Cancer Institute for these studies.
Q. I meant further funding for these studies.
When you didn't get funding for them, you wrote your
Senator, your Congressman --
A. Right.
DORIS O. WONG ASSOCIATES
c-rRHf "i 0`°'f' 2.i. 03

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Q. -- but during the period from 1973, until
the time that Mark Edell put you on the witness
stand 15 years later, you never in writing said
anything about the comments that you now attribute
to Mr. Jacob, correct?
A. I'm not quite sure. I may have mentioned
something in the letter to The Lancet which you
showed me.
Q. Let's take a look at that.
A. Let's take a look at it.
Q. The letter to The Lancet is dated March 10,
1973.
A. Oh, so -- okay.
Q. So it would have been hard for you to talk
about what happened in the summer of 1973. But it's
not in any document you can tell us about?
A. No.
Q. Did anybody ever tell you that the
decisions by the Scientific Advisory Board of CTR
not to enter into additional contracts with you in
1973, 1974 and succeeding years, was based on
anything other than a decision, a scientific
decision, by the members of the Scientific Advisory
Board?
DORIS O. WONG ASSOCIATES
Lmr Tf"~` f f f"f 0"°f' 2.f. 0""'f

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A. I think the only statements they made was
comments on our application. Dr. Gardner wrote me a
letter, and it was purely in scientific talk.
Q. Do you have any basis for believing that
that decision by the Scientific Advisory Board was
based on anything other than the Scientific Advisory
Board's views of scientific merit, however misguided
those views may have been?
MS. SCHNEIDER: Objection to the form.
A. I don't know that.
Q. So as far as you know, there weren't any
other factors?
A. I wouldn't know. How could I know about
them?
MR. KLUGMAN: Just one minute.
Q. Dr. Homburger, were you told consistently
that it was the objective of CTR and of the
Scientific Advisory Board in funding these
inhalation studies to find an animal model for lung
cancer?
A. I was told that from the very start by Dr.
Little and later by Hockett, yes.
Q. And that was true straight on through;
that's what you were told?
DORIS O. WONG ASSOCIATES
CTR I-IN 0421OE5

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A. I wasn't told much about that any more in
the later periods.
Q. But you were never told anything
inconsistent with that, were you?
A. No, I was not ever told that.
Q. And you never developed lung cancer in any
of your hamsters, did you?
A. What did you say?
Q. Your hamsters never developed lung cancer,
did they?
A. What do you mean? Half of them that smoked
developed lung cancer. You mean respiratory
cancer. They didn't develop lung cancer, because
obviously the dose of smoke entering into the lung
was too small. The hamster has a very tight system
of bronchial trees, which is probably 1/100 that.of
the human.
Q. Let me ask you just a couple more
questions. I wasn't clear on your earlier testimony
about the Scientific Advisory Board.
I was clear
about your comments concerning Dr. Gardner and his
lack of expertise in inhalation studies. Let me ask
you first, what was Dr. Gardner's field?
A. Dr. Gardner was an anatomist. He taught
DORIS 0. WONG'ASSOCIATES
i..r TR 11N S..A `"f' 22.f. 0C'"..o
