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Council for Tobacco Research

Summary of Dr. Hocketts Comments [Report of the Surgeon General's Advisory Committee on Smoking and Health]

Date: 05 Mar 1964
Length: 7 pages
CTRMN028479-CTRMN028485
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Abstract

MAR

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Depository Date
25 Sep 1995
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119
120
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Ctrmn00028023-9276

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011
Type
REPORT
UCSF Legacy ID
dos30a00

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a % HK/0998002 TM COQIICIL ?OR SOBACC'0 RS?JIWH - II.S.A. sT?lSAR7 o? M. ZC= ' S OD!!= Mu--b S, 1964 Our atteatiom at this tiae is aaturally tpoa the Aepart of the 9uateoa Ganeral's /ld.i•sory Casolttae on Sacksa aad S.alth. 'b" Eeport bas not actva:l,v eDanged the scientific piettia•e to a7 degree aad coataias little taat is aev. It did not lift the critieal arL17sia of szist.iag dau to any aev or Sigher ylaaa. Like awt eaW-tt.e jobs, it is na.yn In qaalit7, soae ssetioas btS.ns Qnite eosrp.teat rLil,e otLers sea to ns qsilte laa4eqnate. Se.e~ss, tLa R.pWt na+ R:t a rPotliiht oo certain perobless aad baa rather redneed taa liaelislrt on otLars. To sa.. esteat, this ..,U.l latlsisac e tLm aaamt of ss*pLas is w 00" to pat on e ertaia thiap aad tae t~o of ow provsa In sos,e ar.as. Stat irt i ez•1 llrTeets The Report .etnall,7 ralssi Tar7 D.arily ao rpidsiolot ieal data In twehis& its coaelnsions. Altboao St is adsitted that ausocia•.Soas do wt peo.. esasalStY sad taat ebspletal7 soaad ooaclusioas camsot be rwcsed fro. ptas esrt data, Tet taa Cosittee felt ecmpell.d to ake ~ta Muts e gp bQond seisatit'ic ecm,elnsioa and contain an alem.at of gaess and psble. Lace sow otbc Casszittae adsbt ra11 r.aes r.tL.r di.^fsreat aanelnsions a-on the ssae Satarsatim. It is the geasral baDit, novw.ar, aacasd people iaterae-.ed in pnDlic D.alth to ake their arrors on vsat tDe7 cooceive to be the side of easrtioa and safsty. W nsre evasnlt.d a eamsiderable aumDer of statirtieal erper•.s aboat the Rrport. s .arl7 s.ll tLts e are ia a.Rees=t tbat the as s oc :.at i o-..i of diaease inei.daxe vith eiprett. sanYina aast bt acceyted as estabiisbe-r. Mwy do not .x,.ct tbat any re-itody or re-eastias of the presaat data iri1-1 dettrvf the aa s oe iatioass .Thq do nct thi.nlc tLat any wrcrs ia ataea : i:•a:. artbod vill be foaad. Mey all asree, bove.., tbat sueb resias to be l.ars.d ab=t taeee associttioas, particularly tLe s=teat to vhicb tU7 iad:este esusa1::-y. In otbsr vca-ds, tbe real Quastion is vhetbc e igsrettt saolcers dS e acr e freQneatly of disease I tbaa aoc-taokers bscause tbq saokk eiWrttes or is it tbat the kind of people vbo get dia.aue X sre also aars 11ha1y taaa the a.e*aae to b* e iprttt e sank ers tTb pat tDa qo. et ioa aarrtaar wq, ar e noa•.mak.ers (statirtical'a) the kind of people vso sre in senessl ra:her se'- prot.e : i.. aad eaut i ous t L' so, they sight ha.+e les s dL eas e and lcag er lis e s chi efly oa ae c onat of a goe_i of L'.L-g rat.h.r taaa b.essse t•hey d~o flas smoke. Miia poa s ib i•lity vaa not gi..m aay awpDaa ia in the R.port. PLAINTIFF'S %X ~,~..~ .,.... ~ .,. r." THIS DOCUMENT SUBJECT 10 CONFIDENTIAIJTY AGREEMENT, E..r TR F E N 026"C 79
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HKI0998004 3 - Attaehw-s: #+ tbe saae tn".stioa. 'm+ey propose to stad,y a proaabi11t7 .asple oC tb+e =tir. Dnit.d States popalatlan to drterAiae tbe 'Qaa-ralat.s of saaks~.' 43.is s,.aas fisdiM att th. diSfereaces in p.tteras cf litiag os aon-ur.ras as eosrp..r.d to tacs e of ligbt aad besY7 eigarKt. ss+AQS, arp.e ia.ll.7 taos e t.at.a-es of tbs pattera tbat aaJ at:eet b.altb aad loas *rit7. Aa<L stad.ies ars relatively ezpeasin bat ta.y eaa be daoe tairl7 qole.tl,. Ibc.arc , tLq are sa.ething of a paDle, as ail rtse&reb is. But if "ta eaerged, tbey siipt be effective in pattiag tde sruL-paDlieise+d as s oc iat ioas of tigarette aohias aM Eis w e in a a.v light. 2. bes idrs this tS.nd of brond g.,ae; s1 ayproach to the Qaestiaa of tlf:Qeae.s betv.ea saokers aad aon-sackers, tLere are atbc s,are specific ayqrcae3es b.sead m particvlar bTpotaeses. Muese are lsss eos-::,y to yerso+e bat, bs1sK snre 11adt.d ia sctrpe, ere parbaps snre of a pable. B.cause of the pr.seat sitaatioa, vt talak tbct s..eral of these aLoald be parsn.d a11 st aoe e Sa oedes to iacrw e tb. aDaac e of ptt iag .alnab 1 e Saforsstioo as soon as possible. a. 'be pattesas of b.ba.ior vith rerp.et to ssartise, aL.rp, trsaqttilisQS, atc., eaa be 1atQprftad ai aboriat tbe degr*e of 'strsss' in p.ople's lins or bow tb@7 r.act to str.se, ani t,bese patterns aoald De ralat.d to aerta11t7 T+at,es s.parataly lrom tobacco os.. Proposals !ar snea a study are szdar biseassioo. D. Aaatber tare 1Ssit.d Zppotbesia bas be.a pat lor+rsrd b2 a Sarvard prr-D010g11t. $e te7.ls tb>t UI si>r ebLTfCtQistlGS tbat ixt a pasoo ias eas itirs to paia and dSseedart asfl t,bos ralsti.al7 mrals s. aboat ais b..ltn sq be tbose vhiea also aake lia litalT to be a eaetc . Lao e taas ad.ot be a statirtical ralstiea b.tv.aa illaai s aad auo'ciaa .r= tbougb tbe smickly, its e.lt dld not eaase or a~-as : e the illnes s. A l~ss esreh prarposal !!aa tMs iarestisator vill be comatasred Dr7 o= AQ'*is=7 BIDar+i t3s .wY. ~ . / e. Otbrr stvdl es of aaalcsv~s eaar.rtQ ste andss ec,rnsidsration b7 vaa DoLr'd, incl++~+? ~ pi'oposiU Pi'ti Br+t-doads•C, i.1as'Sf aarl ?L:a~c, vhi eD w ri.11 aot diseni s in detail nov. .fta stodi es alr..dy eadt:rvLy vith D rs . Seltzer, n ab.r, =aplaa sad Rsu s sk also are aia.d at •~~ ~; n~' ,~ oa j.ct i. es -- to n1tt: asai,h as..":.r.ae ss brs,r..m aaoYas aaa aom. aakc3 :. . c~ that ay ba.. etTects an hs.ltn aot due to the saokant itaalta kA ~ a. Other statistietl proDlss s ar. also aazq otb.r groblsms bsriaj an the rtatirtiea: yirtvre. /h.oat tasse are: (1) flie peak W od lnas eaac c int id eac e bas b.aa rrport ad bT sevsral inTestigatars to be about the s:ae a.er t,bs 7.ars, rsgardless of tae suppos.d iaera+aae in the incidames of the dls.ase. (Passe7i ToeD.) M%is is mrt eeasirt..art vith the id.a tbat the Saereas e of e igar et'.. sioY:a~ i s a aajor essu e s iae e, in thi s e.as e, the di.s eu e sbon.l4 be rtr'-V-ni at .ar11 er aad .arl1 ss agas.4MIa report n..ds to be tMt.d vith the Uaitad 8tates data. THIS DOCUMENT SUBJECT TO CONFIDENTIALITY AGREEA'ENT• Alzr A'r ~N 0 ~84 ~~
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NKooss8oo5 .1- Attac'saeat #+ (2) DipLrtra's obser.atioa taat (Datcb) peopl.e bara in tae ri.atc y..e ame lsa8 eanc er tLas tbos e barz in the aaac n.eds eb.criaa vith U.9. 4ta. (3ii 2qrpotDtsii ii tbat srly i.?ieiescy of vitas:Ls A aLy predispose to lster 3zmi esaear.) (3) Dr. aiuiaa's obsesratiom taat the rate of i.aervs" of lnag 7 eaaees is taper isK oS: aa.da to be lolloved fa-tba Tear by Tear. • (Dr. Oi11 Sn li e+d last smmic .) (1) Dr. Laaba.rd' • earlS c oaa er.at ion that tbere is a t?a saLa: d acabes of eipretta tLat bstis to bt smY.d bstare thQe i.s arq laes.ase in risk, is Uaiag tast.d v'ith a ar+r body of data. ~~ e^~ ~ (S ) dwing taia esct~ Lhsyal.l, atill tmsol~i+.d,~aad tbere are yos s ible aetaods of gvtt.i.as S'ortbes ligbt m tbe .+ab jeet . Da•..a eoll.etad b7 m. Caaaeil a..d to be rtadSs+d minutaly b7 an szper: •pidadolo~st. (6) srs e!"!e-mecs, rm-i: vs. arbaa iaeiAaaee, the intlasaee of rQ,, /ra~1 ycrrio" lams iatectioos on lrasg eaxc aad otaer yroblew ~° ^f als o naed l=tbw atsdy. N. Smok1as and La3tb of Lsse Aaotb.et w of Crttsad at the qnsttioa of d.at5 rat4e ia rtilatiaa to eiprttte snclriai L to do aaisl rtadies. The prSa. Qasrttoa rais.d aba.e sboct tba wpid.ndnlogieal ttvdSs Lvhetbsr tae aokas aad aoa-saabcs are t5& sam. lHad- of p.ople ia other sstp.cta s.ad vbetbc Te are emtitl.d Ies0esl:T b cowpsre tbrtr Q.ata re.nr l.ds2 .p Io srtt1e t'brs .aal! be to dra peoFl.e's aaaus traa a ba at raadrra sad lwre oas groa2 saoks aiprattsa aad tae other Roay sstzsin Sor BYe. Sa !se t3sm vs eoald tind art vb.t3er there vas asp LISYeraaee in 1/oas.Kt7.. '!SS•s eacperiusat is not , ~^,~:h• tea~sible bsK this ~nd of tert can by daae vith -ni_'. In ralati.aly saa~- ~•~ ~ sea.!e espc'seata, tsta bss baa axpoo ed to frequsat e i.pwvtt. saoYe Srtra:stioa !or .a.Qsrisoa vith umex,o.ed eocrtrols. 'D» ex,oe.d •ns••L• li..d I as lce& aa t.he e oatroL . Tlsis ob s e» nt i•oa s evs to sQpport tae id.a tbat thsre is selectioa ivrolred la tDe Asmaa pDyulitions of ackers aad aoa- saclcar s that ba.i b.aa etmcr e+d aad tu"e-s ta tbat tLu e var e aot ssadoa dl.iiions, siaee tDa ssckini rats d1d not die esrller. Va thialc tbat lsr M-s ezle aaiar l rtvdi es of this Y~d sboald be doae . mq vould b e Quit. stsa.igW.crv.rd aad .aaia s:,laiaed. Karwrc, it wald be possible, ia the eas e of sSe e, to s elxt rtnins tbat nca-na1,7 La.* d.it- ere:rst da greu of londwritT aad vbicD acsraa1:a die froa par'C:rals.r k4adi of di..':icn.:ties characteristic at the •traiss. THIS DOCUMENT SUBJECT TO CONFIDENTIALITY ACREEMENT, ! CTR MN 02~~~~
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r -7- NKi0998008 Attaehae;t #+ Ther. are aany ot3er rnby.eta aadez rtud7 aad in vihich good pro6res. Si being aa0.. Cur eltarta to Leralop blood aad wiam tssta taat aty gis a briter asana• of the estmt of saoka issbalaticm taaa que.tioaoairss s.est to b. pro".S.rg .uy rall. tiis aq soaa be sble to ea.cY t3e Qnsstimaaite repliq of a lar6e aary at taDj.eta aad tlad ont vhethsr the QaettSoamaire replies m inbalstion ar• aay pod at all. A a.at a.al of Ra-iia bas e.en bnilt by apiasi.ologists oc ta. s+.,,w t:oa taat snca Vowstiomaires are reliable. I In tbs field of Oioasaq Sar areiaogaaie st:sets, s bats s.csatly aypli.d a artbod of Satra~ Sty.ctica iato sics tollcvsd by eamting of laag adsacrm. 'lbaaceo ante eoad.easates, W this test, vere ea.pl.tsl7 iaacti... In !'aat, at avery lor lnsl of adxd.aiitratian, tne sseU toadeasat• s.esd to ' ,laraatiaa of tDs l~ tm~ors tbat vosld tie s~cD.ctd ia this straia nbaa tmrtryatsd. Stadiss b7 L3s11. sao..d ao effect of iabalad eipswttu make 0o the rate of elsar+tae • of taaed dnst troa tht 3srtsp of rbols, h.a1t2q raDbits. It voald s.a tbat St tae eilSary wtivity aad aaeus flaw .ars slawd dova b7 tb. sacts, .ae vtbrr el.aaae• •e.b•n<s, perhsps by Pha.Sa7titi, wit betr btta rp..d.d up. G• C4- k+j.c.t •L-44r," . Zr . -8 -P . QNIs DOCUMENT SUBIECT Ta amFlDE+twun AW-Mr. , '~y,," . CTR HN 0*228465

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