Tobacco Documents Online

F4 ^ CL//-( G?aO___ Mr. n4 xe zuPuis • "Ir 24. 19s8 - o. T. xaoO arier oo®ent• on a program to produos a low delivery lilter oSSaretto with ria.or. t2asauoh~a~~ the eTid.iuo ot`Ciinbd~`lro~ss . Aarob•April 1958, Yol. 8, ?io. s bulidi~ ny that heavy cigarette smoking contributes to lung oanoer either aione or In assooiation with eical and physiological faotors such as air pbllution, pr.= disposi ion, nervous tension, rate of lirit~, oto., I believe uo . should inorease the departm ental ettort, both in terms of abort rarge and long range objeotives, towards the detelopment of a low delivery aigarette having good flav+or. Now what should the short raage and long range objeotive• be, and how should we go about it! ror short raage, let's oonoaatrat• on maans to~y oe a sub• stantial reduction In tar delivery, even it it i• only aormss the board, siaoo the ohaAOe i• ~ood that aryr •y~oitio irritant angfor oaroiAogen, it yresent, tKOUld be r.duosd al•o. !or long ranje, • iet~s study means for identifyirg oaroinoganio substances 3s xe11 as all substances in cigarette smoke that ar• irritating or are knoxn to Vrc luce undesirable phy siological -efteots, and tird maa:uo of r.moving hem. Tf the latter appears-to be imposeible, letfs develop a non•tobaooo oigarette which doesn't have them to beg.tn with, Now, how should tre go about itt !or short range, let's inorease the effort on the develnpm ent of a better tilterp giving slightly iess priority to ventitation, Vf,. tobaoco catalysts a.m tobacco extraotion. At tbe same time, let's increase the effort on the flavor P,rogram since this must prooeed . simultaneously with the tilte.r Program. er, since there is evidence that rubber•like odors ~isonrene~the gas phase beoomo more nouaoed as the smoke soi ds are reduoed a charcoal adsorb• iug filter (part of a multiyle component filter) may be neoessary, ks: unless the odor oan be stiaaked by the addition of oertaia flarors. Zhe short range program could be carried out oost eftioientl?, Z thiak, by setting up agrvup In the Researoh Dirision to determine th. best obemioal and "sioal principles or combinations of the two to produoe an efficient -smoko tilter, ftis would be a lLndamental grouy, and would be oono.ro.d " ~`rill with surtaoe•oheaistrT atfd with developing the best ehemioal n~/orp~y •Soal principles r.quir.d to tilter cigarette saoko oomyie~elr with a small r.sistanoe ;~ to a.ir flow. Information obtained here would be passed along to the tilter group In the D.velopaent DiK sion which would be r.sDonsible .. for developing and constructing prototype tilter models and evaluating tbev, based on the fundamental •tudies. ' ' , • PI.AINTIFF'S ` EXNIBIT . i ti.•.'.- x.q..OC CTR MN 02B30'r

. ...L'~.r .2. Drr. R. x. Dulu.is July Q#, 1958 Rbe long range pa~otras rouldst~o~t out or the studies being earri*d out by the lluidasaatal lilt.r group an well as the ottier groups utidameat tb• ltesearab Division nor~cistj an ®oke o2semistrto yre6ras eould be broadened to inalude the study ot~tobaooo !' additivesloatalyst), tobacco extraotioa and linally an all tbetio aerosol to replace tobaooo ssoke it neoeseart. d~ltaneoui~j, other seotioaa of the lt.searoh tirision sbould be makint a strong eltorl to develoD seans to eraluate tAe phraiolot.ioal •~teots ot ssokins. Zaitial studies could be carried out with animals or eer• taia antsal tissues known to be irritateQ_by cigarette amoke, and kmoxa to be susoeytible to cancer when e.x;iosed to known oaroinodecu. Ibe etteot of known oaroinodanu, both alone and in the presence of cigarette a.oke, oould be studied oa the s.nimals or tissues to determine whether oidarette smoke behaves like a oo•oaroinosan. lurther exyeriments could be conducted with cigarette smoke to see i! ! has diroot oaroino;euio aotivitt. disultaneouslJ with those, . the irritatiaa effects or eidarette saoke should be studied, both .~; : oa ar~imals aod hweaas. : , . ~ ~ ~. 'In addition to 'tbese, :.xplorator~r*itudies eotiild be sadi an bumans to determine why people smoke. Dr. Qser ot the Pood i Aud Researab Lb has some pretty good ideas as to how to go about this, and be is writing tbeo to us. Nor. about this at another time. I know this sou '3s likt a wild prodram, but I'll bet that the ' first oompasw to produoe a oi~arette olaSmiay~1 a subst tial reQuo- ' tion (asy 50¢ less than the present ?arilament and ICent~in tars ss~0 niootine, or an •raats oitarette whose smoke contains no tobacco :` tars, and with good ssoking tlaror, will take the.market.- hrther, ~i it be has the iAtestinal fortitude to J%un Wtho other side of the taaoe proria.d be baa sons convincing exy.rlsental eridenoe to back bis uD oA the issue of tobacco ssokin; and Aealtb, juat look shat a Yeal of aawunition would be at his disyosal, Cf eourse w would bave to be careful to iAtar that the reason !br the e~ar;e ia dress was the oontilALlAs evidence 1tnk1n j o•isa2"ette ssfokiac with baaltb, aAd that altAw;A the evidence is not sltoQether irreMtable "; we have decided upoa tttiis course of aotioa iA the publio intarsst. Zn this wayr, we haw protected our bridges behind us beaause we bate ~ not admitted tbere is a direct relation between smoking arA bealtb, and we ar. buildirg nev briddes ahead WAob xe will need it there is a tlood, but wdtiah Ye rill not Aeed it there is Ao tlood. Za othar xordi, we aro plannirg for the worstj and in tbe esa4 it proves un- A.aeaary ia the tuture, the exyerienoe gained should be weitil !or other yurposts. • • /ej (7 0 • V'TR- I H N 022 6 3 0 8