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Council for Tobacco Research

N.C. Company 1rst to Admit Tobacco Link to Rat Cancers [Discussion on How Liggett & Meyers Company Is the First Cigarette Maker to Acknowledge That Tobacco Causes Cancer on Lab Animals]

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Length: 2 pages
CTRMN028055-CTRMN028056
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Depository Date
25 Sep 1995
Master ID
Ctrmn00028023-9276

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Author
Friedman, S.
Request
119
120
Type
NEWS CLIPPING
Box
011
UCSF Legacy ID
yls30a00

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Page 1: yls30a00
wasr.'( 7tlrs. d1o11e's body Inside body of a man who apparently ptait. What happened to M.rs. nr.r• n. ;er called the scene "one hell of a are people Spread all over the seen nothing like It." re lighter. Daryl Ilolman• said he >t survlvors. ' • . • All I seen was ess rr.alnta!n [Klalor• 1 ra1~t1 rr,erca- .rlon re• nNil a. t surlac- ,?nsa an• a favor- Ronsan .ts sector 3~-a1 and enth Day Advenllst Church, where they had been addressing envelopes. "We saw pieces failing all os•er and •:o we ran back In here so we wouldn't tct hit on the head," Daisy Creese sald. Wreckage was everywhere - a section of wlng, a palr of glasses, a broken key, a plastic key rlng, an attache tase. The fuselage of the smeller plane was In the middlo of a street. A man i body was Inside. ,. f st ron=ly ~! St.utrs, .., a public ~ ~ agua for . ~ et-illy to . a tet:er .clco. Co- R.publlc s, Co/ 1 uts rwer. Pre><idcut Somoza . . . Jn potrcr until 181 ? J (L \..: t/I'li`jJ11~1, J ~ . We can, Ices, s'^n .a1;nC~M .c . /Ai cqm- r.p 04,14 . - •...... return of the Slnal 1o Eg1•pt, In full or "e.•erylhlng agreed upon at Csmp Das1d will be nolllrled' tieiln s.as expected to muster aw oar.:helrrung majrsrlty o/ sh.• 1'0 rrKml.ers when the 1as.•make:s declde WcdnesdaV or Thursday on tAe two sjreements he negotiated 1 he smallcr plane, accordlng to wllnessrs, smaslied Into the lip of Ihe jetliner's right wlng, then fell aw ay as the big Jet's wing e.plod ed Into Ilre. Robert Medonla, 17, a hlgh school student who llves under the Lindbergh Fleld approach, sald as soon as the right wing caught flre the airline pilot pulled the plane's ont0 her homnC. "My slster's lyine there burncd to death." lie said• sobDinG. John F.dsington, a union otllcial driving to his ot/ice In nrarby hlls• slon Valley. said he "could see fire shooting out of the right side o/ the plane. "It Just went stralght down. See 111 DIE rate iA, Col. I N.C. G'oni~aany 1st To Admit Tobacco Link To Rkat Caucers tay SAUL FRIEDMAN 0777 w..MMw a....w WASHINGTON - Llggett 4 Myers,•a leading to• bacco company, apparently has become the first clifa- rette maker to acknowledge tobacco produces cancer In laboratory animals. The acknowledgment - In a patent application for a possibly safer cigarette - was the first public adrnlsshn by the Industry of a llnk between tobacco and cancer, researchers told The Observer•s Wash/ng- ton Bureau. Dan Provost, a spokesman for the Durham.based LIEgett & Myers. sald he did not know If his company or the Industry ever has acknowledged the tobacco- canc.r relationship In laboratory animals. But even It the Industry had conceded the point with regard to anlmals. Provost sald, such experi- ments prove nothing about possible effects of smok- Ing on humans. The Industry has conslstenlly ma/n- lalned a link has not been established. The patent was granted Oct. 25 to Llggetl & Myers and tsvo of Ils researchers. Vello Norman and llerman Bryant Jr., the Inventors. Norman• of Ra- telth, and Bryant, of Durham, assigned the ownership e of the Inventlon to Liggett k Myers. The application described e.perlments with mice, whose skin was palnted with three kinds of tobacco substances. Mice painted with untreated tobacco de- vetoped skin tumors more frequently than those painted with various chemical additives. The patent application clalm;d when a form of the metallic s-ibstance• palladlum, was added to to. bacco with other chemicals. "the amwnl of hyCro• carbons In tobacco Is reduced and a substantially diminished biological activity of the tobacco smok- e ... on experimental animals ... is achieved ` Dr. Dietrich Iloffman, a blochemist and researcher for the American I/talth Foundatlon, said the tobacco industry frequently uses the phrase `blolo:/cal acti.i- ty° to describe bodily changes such as the growth of tumors. Inventors Norman and Bryant swabbed the sklns of three groups of 30 Inlce. with condensed tobacco smoke for 80 aeeks. Group A was painted .vith a r.bsta.ce containing See N.C. COMPANY rate GA, C.L 3 in Asks Israeli Parlia'Me"all nounct I Jordan's Klnj Husseln has decided atalnat a mid-October trlp to rhe United Stares but would probably come later. Jordanian sourcet•sald flusseln would visit othct Aral, lesd.rs thr- .veel.. Ilus?eln's partlclpalion Is con.id- tred clvclal /or talks on the future ..1 .A, 1.... ...., A \•' . L .wl' irv's leaders are dissatisfied with set deputy from BegIn's Llkud the acc:reds because they (gnore bloc. dssruptld ltegln•s address aod the Palestine Liberation Organ/ta- was ejected /ros 1he chambrr. tlon. ( ''ed des officials say Bec/n prn...•,.•d _: Camp Dav!d to halt eon!tructnsn of settlements durir.C the five•year negotiating period on F(J) E rl r. a (.8 r / . (J tt . . . 4
Page 2: yls30a00
rs :. . . - N. C. Company Adrrtiits Tobacco, Cancer Link .~t. } CoetJnurd from Page IA they have not developed skin can• toDacco treated with palladium cer,'• he said. "Perhaps skin can- ii, abne. Group I was painted with cers develop In mice• but that has w t hi d i h [ k , talnlnl, palladium and maCnesium lua9s• urw. . + c nttra a e:a y r e t a t ~=roup v+ts palnted with a smoke Ilat•ins It Both TVQ1'•t condensate of untreated toDacco Speaking for Uggett 4 Myen, from non•fllter cigarettes. Provost said, "Evrn if you could ' In a key conclns,nn, Norman and ~j produce cancers on the skln of 'n%ol.e th. Human oelnt~ mav de.elnp )'el• low /hnceri frnn~ e%~•~rPitri 1iy produced the earliest and highest scance on the wrong ttssue• oa the ;. ~,Inddence of tumors" amonS the \vrong species la the wrong f i ~ o o amo condtnsed toDacco smoka con- not n~ e and " h n d Tl ontrol t iryant repontd untreated tooatco micsa condtnsate is tht wrong suD• ce. tAree groups o m amounts" That wordlnd, said Hntfman. la Seewln ~Valn;row, a_ puDlic .~- -'- .. .1•.., ' working directly fnr a tobacco J company has acknowled=ed such a 1 nlatlonship between tonacco and 1 cancer• They have never made 7 S such an admisaion Defore." On occasion, Hoffman added, ra ~` .. ! searchers under contract to the in• dustry or a toDacco comr,any have : made the sarne tlndlngs in txperf• d roents. \ "The companies. In such eases, health re-tearcher with lht got'ern• ment's Office of Smoking and Itenlth, noted, however, the patent claim by LiCtett & Myers wrd the mouse-skin experiments. "•fhty can't have it both ways," he sald. "They can't say tapert• ments on mice are not relevant and at the samo time ust such esperi• ments to support• their (patent) claim." Provoat declined comment on do not legally accept respnnaiDilit,v ' the patent except lo say "It's on(t ~..' ~ ~. for the tontlusion.t of thrat inde• nf doatns of things we ue work. •..,' prndent researchers." Ilnttman inC on." Laid. ~ . n iliid ront Esteli s~ T J ;S lie/ett(nt To ~l•1((ry ti7o Were Wrong Dr. RIchard [Jtls, aearcher for a private consulting troup, agreK: '1 am not personat- ly aware of anyone (lo the tohacco Industry) making such a comment about the relationship Detween to- Dacco and eancer, even in miee. tor public dlsclosure.' Dr. Robert Hockett. researcher dlrector for the Industry•funded Council for Tobacco Rrttarch, sald. "I don't know thal Ihit asser• lion has heen m3de Uv xnlnronr in the industry. The Innuqtry has not Conr out of iU weY to nlake such atatements." Even so, Hockett said, painting concrntrated tobacco cnnnensate ne S~•noGa on tnr bkln of mlce, "is not rtle• 't`' p0i,tIcsl ~snl in nlan. 1o• 'jn ,.• The wrong phototraph of K u w alt's ne w chief of stlte. JeDer al•SaDah, was used in Sundav and Monday•s OD• server. The cor• rect picture is at left. CLI.'!i V•0 :ltis \Vnte SalurAar K.•Irnnnk• farnli• n~ I r..ne 1)rt`.irlnlrut, I hr ('liv (lh.rrvrr P r). ti0% Itla. ('harvlv, ,4 r ~ausrt to~s~~uC-~>t f~tru~s • Another comforting idea from t....,...... r.r " : .'r:. / _ : .,,...-... .• F...:... ,_, .... .... .. ....... f......rr.•.•.+ti, ntin)L.~tt).1: IN C•1~)t•:1. S l3LACK Ll:,.•r)IL•IZ '33•9_9 - r~ "(.Ilarltlltr'. I.;,r_r•l ~ ~ ~nt- •i •. .. P G t~^i G~. :. Shop c~I EL L CtR t t t"'f 02BOE-56

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