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CURRICULUM VITAE OF DR. KENNETH MERRILL LYNCH Dr. Kenneth Merrill Lynch, Chancellor and Professor of Pathology, Medical College of South Carolina, Charleston, was born in Hamilton County, Texas, on November 27, 1887. He received his M.D. from the University of Texas in 1910, and holds honorary degrees from the University of South Carolina, the College of Charleston and Clemson College. He served as Resident Pathologist at Philadelphia General Hospital in 1911 and as an Instructor in Pathology at the University of Pennsylvania, 19u-13• He became Professor of Pathology at the Medical College of South Carolina in 1913, Vice Dean in 1935, Dean in 1943, President and Dean of the Faculty in 1949, and Chancellor at retirement under the South Carolina State Retirement System in 1960. He was Captain in the U.S. Army Medical Corps in World War I and was Medical Aide to the Governor of South Carolina in 1918. He was the recipient of the Gold Medal in the Scientific Exhibits of the American Medical Association in 1920 and of the Research Medal of the Southern Medical Association in 1921, as well as the Distinguished Service Award of the Southern Medical Associaticn in 1957 and the Distinguished Service Citation and Medal of the American Cancer Society in 1958. Dr. Lynch has held membership in the South Carolina State Board of Health 1935-44, of which he was Chairman 1940-44; the National Board of Medical Examiners (regional) 1935-42; the South Carolina Cancer Commission, of which he was Chairman 1939-''4. He is a Fellow of the American College of Physicians, serving on its Board of Governors 1925-27 and 1936-47. Among the memberships and official positions in medical and scientific societies and organizations held by Dr. Lynch are the following: American Medical Association, Vice President 1935-36, and Chairman of the Section on Pathology 1924; the American Society of Clinical Pathologists, President, 1930-31; American Society of Tropical Medicine, President, 1930-31; South Carolina Medical Association, President 1930-31; Southern Medica: Association, Chairman of the Section on Pathology in 1925 and Councilor fer South Carolina, 1935-40; American Association of Pathologlsts and Bacteri- ologists; American Society of Cancer Research; American Cancer Society, member of the Board of Directors of the parent society, 1939-43; Public Health Service's National Advisory Neurological Diseases and Blindness Council, 1957-61. A former member of the Editorial Boards of the American Journal of Tropical Medicine, the American Journal of Clinical Pathology, and the American Journal of Digestive Diseases and Nutrition, Dr. Lynch is the author of Protozoan Parasitism of the Alimentary Tract, The Macmillan Company, N.Y., 1930, and American Editor of Green s Manual of Patholo , Balliere, Tindall and Cox, London, and Wm. Wood, Baltimore, 1934. He has published more than one hundred scientific reports and papers. 121561 6-5100 £:;:- CTR HN 011163

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CURRICULUM VITAE HANS ME IER Born: 21 July 1929, Zurich, Switzerland Nationality: United States citizen Education: University of Zurich (Veterinary Medicine), D.V.M. 1954 University of Zurich (Pathology) • Dr. med. vet. 1957 Harvard School of Public Health 1957 Massachusetts Institute of Technology, Alumnus (Biophysical and biochemical cytology, biology) 1959 Honors: Royal Society of Health (Pharmacology) M.R.S.H. 1963 Member, Scientific Advisory Board, The Council for Tobacco Research, USA 1971 - Member, Solid Tumor-Virus Working Group, Special Virus-Cancer Program, National Cancer Institute, NIH 1971 - 1973 Member, Breast Cancer Virus Segment, National Cancer Institute, NIH 1973 - Member, Scientific Advisory Board, Institut de la Vie 1974 - Member, Virus Cancer Program Scientific Review Ca~aittee A, National Cancer Institute Major interests: Experimental pathology, cancer Positions: 1970 - The Jackson Laboratory, Senior Staff Scientist 1974 - 1970 - The National Cancer Institute, Consultant 1962 - 1970 Th e Jackson Laboratory, Staff Scientist 1960 - 1962 The Jackson Laboratory, Associate Staff Scientist 1957 - 1960 Harvard Medical School, Res. Asst. (Pathology) CTR ( ; i ; 0.i 1.L G`{

1958 - 1960 Children's Hospital and Medical 1957 - 1960 Center, Boston, Asst. (Experimental) Pathologist Children's Cancer Research Foundation 1954 - 1957 Res. Asst., Res. Assoc. (Exp. Pathol.) Angell Memorial Hospital, Boston, . Fellow, Resident, Chief of Pathology Postgraduate training: - 1955 - 1957 Harvard Medical School, Course Work 1957 in pathology and neuro-pathology Harvard University, Summer School of 958 Arts and Sciences, and of Education (Biophysics and radioactive measure- ments) Armed Forces Institute of Pathology 1959 (Course in histochemistry) Harvard University, Depts. Biology, (Electron microscopy) and Chemistry (Experimental methods in biochem.) Societies: N. Y. Acad. Sci.; Soc.'Exp. Pathol.; Int. Acad. Pathol.; Amer. Soc. Pathol. and Bacteriol.; Cancer Soc.; Histochem Soc.; Amer. Soc. for Cell Biol.; New England Soc. Pathol. A.A.A.S.; Conference Res. Workers in Animal Diseases; Royal Society of Health (M.R.S.H.); Soc. Exp. Biol. tied. CTR HN 01116~`~

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CURRICULUM VITAE Gordon Barry Pierce, Jr., M.D. Personal Statistics: Born July 21, 1925, Westlock, Alberta, Canada Married, 5 children Immigrant Visa, eligible U.S. citizenship Military Service: Canadian Army, 1943-45 Education: University of Alberta, 1950, M.Sc., Anatomy University of Alberta Faculty of Medicine, 1952, M.D. Interne, University of Alberta Hospital, 1952-53 Marine Biology Course, uood's Hole, Massachusetts, 1959 Professional Record: Licentiate, Medical CoJncil of Canada, 1953 Lecturer in Pathology, University of Alberta, 1953-55 Sarah Mellon Scaife Fellow in Pathology, University of Pittsburgh, 1955-59 Diplomate of the American Board of Pathology in Anatomic Pathology, 1957 Assistant Professor of Pathology, University of Pittsburgh, 1958-61 Associate Professor of Pathology, University of Michigan, 1961-64 American Cancer Society Professor of Pathology, University of Michigan, 1964-68 University of Colorado, 1977-present Professor and Chairman, Department of Pathology, University of Colorado Health Sciences Center, 1968-present Awards: Pope Memorial Gold Medal in Medicine, University of Alberta, 1952 Sarah Mellon Scaife Fellowship in Pathology, University of Pittsburgh, 1955-59 Markle Scholar in Medical Science, 1959-64 Guiteras Lecturer, American Urological Association, 1962 American Cancer Society Career Professorship, 1964-present Medical Alumnus of the Year Award, University of Alberta, 1968 McFarlane Visiting Professor of Medicine, University of Glasgow, Royal Infirmary, 1979. bS.Gl'i .,_47 CTR i i i i T 01116B

Society Memberships: American Society for Cell Biology American Association for Cancer Research American Association for the Advancement of Science American Association of Pathologists (President, 1977) Federation of American Societies for Experimental Biology (President, 1978) International Academy of Pathology Pluto Club Society for Developmental Biology International Society for Differentiation (President, 1978-present) American Pathology Chairmen Committees: Medical Scientist Training Committee, NIH, 1965-1968 Editorial Board, ~Labor~at~or! Investigation, 1967-1978 Editorial Board, Deve pmenta ~Moogy, 1968-1973 Editorial Board, ncer Research, 1970-1975; 1980-1984 Cell Biology Study ection 1968-1972 Pathology B Study Section, NIH, 1973-1977 American Cancer Society Committee on Personnel, 1968-1972 Chairman, Meritorious Awards Committee, American Society Experimental Pathology, 1969 and 1970 Program Committee, American Association for Cancer Research, 1973 and 1974 Councillor, American Society of Experimental Pathology, 1973 Secretary, American Society of Experimental Pathology, 1975 Member, Select Committee on Priorities and Planning, FASEB, 1974-1975 Director, Colorado Division, American Cancer Society, 1972-1978 Vice President, American Association of Pathologists, 1976 Treasurer, International Society of Differentiation, 1976-1978 President, International Society of Differentiation, 1978-present President, American Association of Pathologists, 1977 President, Federation of American Societies for Experimental Biology, 1978 Council of Scientific Society Presidents, 1978-present Board of Scientific Counselors, Division of Cancer Cause and Prevention of the National Cancer Institute, 1978-present Committee for Planning and Projection of the American Cancer Society, 1978-present 6:,10-1 __'yS CTR HN 011169

BIBLIOGRAPHY Gordon Barry Pierce, Jr., M.D. 1. Pierce, G. B. The Iron Content of Mammary Epithelium. Master's Thesis. University oM~erta `[ibrary, . 2. Rawlinson, H. E. and G. B. Pierce. Iron content as a quanti- tative measurement of the effect of previous pregnancies on the mammary glands of mice. Endocrinology 46: 426-433, 1950. - ' 3. Rawlinson, H. E. and G. B. Pierce. Visible intraepithelial iron in the mammary glands of various species. Science 117: 33-34, 1953. 4. Rawlinson, H. E. and G. B. Pierce. Differences in mammary gland development among different mouse strains as measured by the iron content of the gland. Proc. Amer. Assoc. Cancer Res. 12: 289, 1952. 5. Pierce, G. B., E. l. Verney and F. J. Dixon. The biology of testicular cancer. I. Behavior after transplantation. Cancer Res. 17: 134-138, 1957, and Proc. Amer. Assoc. Cancer Res. 2: 239,-T951. - . 6. Pi erce, G. R., F. J. Di xon and E. L. Verney. The bi ol ogy of testicular cancer. II. Endocrinology of transplanted tumors. Cancer Res. 18: 204-206, 1958. 7. Pierce, G. B. and F. J. Dixon. Testicular teratomas. I. The demonstration of teratogenesis by metamorphosis of multipotential cells. Cancer 12: 573, 1959, and Fed. Proc. 17: 453, 1958. 8. Pierce, G. B. and F. J. Dixon. Testicular teratomas. II. A teratocarcinoma as an ascites tumor. Cancer 12: 584-589, 1959. 9. Pierce, G. B., F. J. Dixon and E. L. Verney. Endocrine function of a heterotransplantable human embryonal carcinoma. Arch. Path. 67: 204, 1959, and Proc. Amer. Assoc. Cancer Res. 2: 33~, 1958. 10. Verney, E. L. and G. B. Pierce. The biology of testicu- lar tumors. III. Heterotransplanted choriocarcinoma. Cancer Res. 19: 633, 1959. 11. Midgley, A. R., G. 3. Pierce and F. J. Dixon. The nature of colchicine resistance of the golden hamster. Science 13,3: 12. 40-41, 1959, and Fed. Proc. 18: 495, 1959. Pierce, G. B., F. J. Dixon and E. L. Verney. An ovarian teratocarcinoma as an ascitic tumor. Cancer Res. 20: 106-111, 1960, and Proc. Amer. Assoc. Cancer Res. 51-52, -T 1959. _ CTR HN 0 111 't''o

13. Pierce, G. B. Choriocarcinoma of the testis: Discussion of paper. Ann. N.Y. Acad. Sci. 80: 174-177, 1959. 14. Pierce, G. B., F. J. Dixon and E. L. Verney. Terato- carcinogenic and tissue forming potentials of the cell types comprising neoplastic embryoid bodies. Lab. Invest. 9: 583-602, 1960, and Proc. Amer. Assoc. Cancer Res. 3: T41, 1960. 15. Pierce, G. B., F. J. Dixon and E. L. •Verney. A critical evaluation of furacin as an anti-testicular tumor agent. Urology 84: 569-574, 1960. ' 16. Pierce, G. B. Teratocarcinomas. A Problem in Develop- mental Biology. ourt na ian Cancer nference TT._Te_gg, e., Vol. 4. Academic Press, New York, 1961, pp. 119 137. .17. Pierce, G. B. and E. L. Verney. An in vitro and in vivo study of differentiation in teratocancinomas. Cancer T4: 1017-1029, 1961, and Fed. Proc. 19: 247, 1960. 18. Midgley, A. R. and G. B. Pierce. Effect of colchicine and x-irradiation on the differentiation of human embryonal carcinoma. Cancer Res. 21: 545-549, 1961, and Proc. Amer. Assoc. Cancer Res. 3:- 13T,- 1960. 19. Midgley, A. R., G. B. Pierce and W. 0. Weigle. Immuno- biological identification of human chorionic gonadotropin. Proc. Soc. Exp. 8iol. Med. 108: 85-89, 1961. 20. Pierce, G. B., A. R. Midgley and E. L. Verney. Therapy of heterotransplanted choriocarcinoma. Cancer Res. 22: 563-55', 1962. 21. Midgley, A. R. and G. B. Pierce. Immunohistochemical localin zation of human chorionic gonadotropin. J. Exp. Med. 115: 289-294, 1962, and Fed. Proc. 21: 198, 1962. 22. Pierce, G. B., A. R. Midgley, J. D. Feldman and J. Sri Ram. Parietal yolk sac carcinoma. Clue to the histogenesis of Reichert's membrane of the mouse embryo. Amer. J. Path. 41: 549-566, 1962. 23. Kleinsmith, L. J., G. B. Pierce and A. R. Midgley. Nephrotoxic roles of antibodies against endothelial and epithelial components of glomerular basement membrane. Fed. Proc. 22: 256, 1963. 24. Pierce, G. B., A. R. Midgley and J. Sri Ram. The histo- genesis of basement membranes. J. Exp. Med. 117: 339-348, 1963, and Fed. Proc. 22: 256, 1963. -. .` t ~!(3 e C 2 ` C 1s~ 11-11 N 0 1117"' 1