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CTR HN 01 1021

CURRICIJLI!M. 1,iT.;F.
ROBERT JOSEPH HUEBNER
Born: Cincinnati (Cheviot), Ohio
February 23, 1914
Marital Status: Married
Present Address: National Cancer Institute, Bethesda, Maryland 20014
Home: R.F.D., Ijarasville, Maryland 21754
Education: 1952-1935 - Xavier University
1937-1958 - University of Cincinnati
1938-1942 - M.D., St. Louis University Schcol of Medicine
Experience:
Military: 1942-43 Internship in U.S. Public tlealth Servi ce Hosr)i zal ,
Seattle, Washington (Assigned to U.S. Coast Guard)
1943-44 Medical Officer ir. Coast Guard, Alaska (;or.anand
Government: 1944-49 Commissioned Officer, USPHS, Laborptorv of Infectious
Diseases, National Microhiologic2'_ Institute,
National Institutes of Health, Pethcsda, Maryland
1949-56 Chief,*Section on Virus and Rickettsial Diseases,
Laboratory of Infectious Diseases, National
Microbiological Institute
1956-68 Chief, Laboratory of Viral Disenses, 'ja*.cnat
Institute of Allergy and ?nfec'ious Diseatc:.,
National Institutes of Health, Bethesda, Maryland
1968- Chief, Viral Carcinogenesis Branch, ::ztional
Cancer Institute, Bethesda, Maryla:i;~
Memberships and
Affiliations:
Fc11o.-:
American Public Health Association
American Medical Association
New Yoric Academy of Sciences
Menber: National Academy of Sciences
American Epidemiologic2l Society
International Union Against Cancer
American Association for the Advancement o: Sciences
Federation of American Societies for Experinental Biology
American Association of lmnuzoloFists
Ancrican Academy of Microbiology
American Association for Cancer Research, I::c.
The J ane Coffin Childs Memorial Fund for Medical Research-
Board of Scientific Advisers
[
Ec-130 b_:4
C`~R H~~ 01102
~

CV - Robert J. Huebner (Cont.)
Honors and Awards:
Award (Certificate of Merit) for Scientific Exhibit on Rickettsialpox,
American Medical Association, 1947
Award (In Biological Sciences), Washington Academy of Sciences, 1949
Bailey K. Ashford Award (work on ri ckettsial diseases), American
Society of Tropical Medicine, 1949
Award (Certificate of Merit) for outstanding quality of educational
,~,xhibit on the Epidemiology of Q Fever. American Veterinary !tedical
Association, 1950
Citation ("In recognition of ... accomplishments in unravelling disease
causat:on in children..."), Variety Children's Hospital, 1960
James D. Bruce Memorial Award, American College of Physicians, 1964
Pasteur Medal, Pasteur Institute, Paris, France, 1965
Honorary Degree, Doctor of Laws, University of Cincinnati, 1965
Distinguished Service Medal, Public Health Service, 1966
. .%F !'.., r~nn 10l+Q
National Medal of Science, 1969
Honorary Degree, Doctor of Science, Edgecliff College, Cincinnati, 1970
Kim:ole Methodology Reseerch Award, Conference of Public Health
Laboratory Directors, 1970
Rockefeller Public Service Award, 1970
Honorarr Degree, Doctor of Science, University of Parma, Italy, 1970
Guido Lenghi Award, National Academy of the Lincci, Rome, 1971
Hor.c,:ary Degree, University of Lcuvc :, Lcuven, Eclgiu^., 1973
6-:7 _.'~ 6?_5
CTR i t t''l 011023

CV - Robert J. Huebner (Cont.)
Eonors - Selected to Deliver:
Gehr.ra-in Lectures, University of I11in:,is College of Medicine, 1955.
Benjamin Knox Rachford Lectures, University of Cincinnati, 1956.
Eli Lilly Lecture, 1957.
Gudakunst Lecture, University of Michigan, 1958.
3arvey h ctu_Te, 1960.
R. E. Dyer Lecture, 1960.
Carl Puckett Lecture, 1960.
A=^rican Academy of Cra,l Pathology, Helen Franc:s McLain Lecture, 1?65.
Uasteur Institute Lecture, 1965.
GAiiteras Lecture, 1568.
Ricketts Avard Lecture, 1968.
William O'Brien Professorship Lecture, Minnesota Chapter of Aner:ca.
Cancer Society, 1972.
Frontiers in Biology Lecture, IoMa State University, :972.
Southern Medical Association Lecture, University of Texas Medical B:anch, 1973.
I:egents' Lectureship, Uriversity of Californis, Davic, 1974.
6`__e2 E116
!-r TR ! l t '1 011024

PU°LICATIONS
Robert Joseph Huebner, M.D.
I. Huebner, R.J., Stamps, P., and Armstrong, C.: Rickettsialpox. f newly
recognized rickettsial disease. I. Isolation of the etiologic>"
agent. Pub. Health Reports 61: 1605-1614, Nov., 1946.
2. Huebner, R.J., Jelli'son, W.L., and Pomerantz, C.: Rickettsialpox.
A newly recognized rickettsial disease. IV. Isolation of a ricReTtsia
apparently iden?ical with the causative agent of rickettsialp:x `ro^n
aliodermnnyssus sancuineus, a rodent mite. Pub. Health Repor-s _
1677-1712, Nov., 1946.
3. lopping, N.H., Shepard, C.C., and Huebner, R.J.: Q Fever. An
logical comparison of strains. Amer. J. Hyg. 44: 173-182, Ju.., I>:.6.
4. Huebner, R.J., Jellisor., W.L., and Armstrong, C.: Rickettsia!;,cx.
A newly recognized ricketTSial disease. V. Recovery of ric-e"_ -
k ri from the house mouse (Mvs_ muscg.lu_s). Pub. Health Repor-s 6
777-780, May, 1947.
5. Greenberg, M., Pellitteri, C., Klein, I.F., and Huebner, R.J.: RicKe"tsial-
pox. A newly recognized rickettsial disease. II. Clinical c--=e-%'a-rior,,.
J.A.M.A. 133: 901-906, March, 1947.
6. Hershberger, L.R., and Huebner, R.J.: A report on the histopatho!::r of
ine cuTOneous jesions or a case ot rickettsialpox. P;;t. He_:--
62: 1740-1742, Dece^oer, 1947.
=e~~rt
7. Spicknall, C.G., Hueoner R.J., Finger, J.A., and Blocker, W.P.:
of an outbreak of Q fever at the National Institutes of Hea!t`.
I. Clinical fe3tures. Ann. of Int. Med. 27: 28-40, July, I9-'-.
B. Huebner, R.J.: Report of an outbreak of Q fever at the National irs-itutes
of Health. 11. Epicemiological features. Amer. J. Pub. Heal-r. _
431-440, April, 1947.
9. Huebner, R.J., et a!: Rickettsialpox. General considerations o` a newly
recoonized rickettsial disease. The Rickettsial diseases of M->r. -
publisheC by the American Association for the Advancement of Science,
p. 113, 1948.
I(,. Huebner, R.J., Jellison, W.L., Beck, M.D., Parker, R.R., and She--arc, C.C.:
Q fever studies of Southern Califorr,ia. I. Recovery of Ricker-sia
burneti from raw milk. Pub. Health Reports 63: 214-222, Feb., ;~~E.
11. Jellison, W.L., Bell, E.F., Huebner, R.J., Parker, R.R., and Welsr., ~.N.:
Q fever Studies in Southern California. IV. Occurrence of Caxie;ie
burneti in the spinose ear tick, Octobius meonini. Fuo. Heal'n F:eDorts
63: 1453-1489, Nov., 1948.
~t
C T R N N 0 11022

Robert J. Huebner, Publications (continued)
12. Jellison, W.L., Ormsbee, R., Beck, M.D., Huebner, R.J., Parker, rr.= and
Bell, E.J.: 0 fever studies in Southern California. V. Na-ur=_! in-
fection in a dairy cow. Pub. Health Reports 63: 161I-1618, Dec., 1948.
13. Huebner, R.J., et el: Q fever studies in Southern California. VIII. Recovery
of Coxiellr burneti frorn butter made from naturally infected anc unpaSteur-
ized milk. Pub. Health Reports 63: 1712-1713, Dec.,1948.
14. Shepard, C.C., and Huebner, R.J.: Q fever in Los Angeles County. Descrip-
tion of some of its epidemiological features. Amer. J. Pub. Heai-h 38:
781-788, Nov., 1948.
15. Huebner, R.J., Hottle, G.A., and Robinson, E.G.: Action of strectomvcin
in experimental irfection witt: Q fsver. Pub. Health RsporTs _
357-362, March, 1948.
16. Spicknall, C.G., Terry, L.L., and Huebner, R.J.: Treatment of C =ever with
streptomyc i n. A case report.
Nov., 1948. Am. J. Trop. Med. 2-7,: tvo.6,
17. Beck, M.D., Bell, J.A., Shaw, E.W., and Huebner, R.J.: Q fever sTudies in
Southern California. II. An epidemiological study of 300 cases. Pub.
Health Reports 64: 41-56, Jan., 1949.
8. Huebner, R.J., Jellison, W.L., Beck, M.D., and Wilcox, E.P.: Q fever
studies in Scithern C--Ii`.ornia. III. Effects of pasteurizaticn on
. ~ . . . ~ . ~ . ~ ~ - ~ - . . . ~. ~ . - .. . ,~ . . . . - ~ . - r
64: 499-511, April, 1949.
19. Huebner, R.J., Jeliison, W.L., and Beck, M.D.: Q fever. A review of
current knowledge. Ann. of Int.. Med. 30: 495-509, March, 1949.
,0. Bell, J.A., Beck, M.D., and Huebner, R.J.: Epidemiolooic studies c' G fever
in Southern Califcrnia. J.A.M.A. 1A2: 868-872, March, 1950.
21. Luoto, L. and Huebner, R.J.: Q fever studies in Southern California.
IX. Isolation of (,
infecTed dairy cows. fever
Pub. organisms from parhrienY placenTas c4 naTurally
Health Reports 65: 541-544, April, 19=J.
22. Jellison, W.L., Welsh, H.H., Elson, B.E., and Huebner, R.J.: Q fever studies
in Southern California. XI. Recovery of Coxiella burneti from milk of
sheep. Pub. Health Reports 65: 335-399, March, 1950.
23. Huebner, R.J.: Rickettsialpox and Q fever. (Symposium on Viral ar.C
Rickettsial Diseases). Bacteriological Reviews 14(3): 245-257, Sept., 1950.
24. Huebner, R.J., Armstrong, C., Beeman, E.A., and Cole, R.M.: Studies of Cox-
" sackie viruses - Preliminary report on occurrence of Coxsackie virus in e
Southern Maryland co-nmunity. J.A.M.A. 144: 609-612, 0ct., 19;-.
.5. Huebner, R.J., Ransom, S.E., and Eerman, E:A.: Studiez of CoxsacKie virus.
Adaptation of a s~rain -oD chick embryos. Pub. Health Reports _ EO?-
806, June, 1950.
_='_00 6116
~T f~ HN 0110*26

RoSe-+ J. Huebner, Publications (continued)
26. Ransom, S.E., and Huebner, R.J.: Studies on the resistance of CcYieile
burne-t i to phys ical and chemical agents. Amer. J. !-lyc. 53: I!
Jan., 1951.
27. Luoto,'L., Huebner, R.J., and Stoenner, H.G.: Q fever studies in Sou-hern
California. XII. Aureomycin tr eatment of dairy cattle natureiiy in-
fected with Coxiella burneti. Pub. Health Reports 66: 199-204, Fee., 1951.
29. Huebner, R.J., and BeII, J.A.: Q fever studies in Southern Califor^ia.
Sum-nary of current results and a discussion of possible control .^eesures.
J.A.M.A. 145: 301-30:, Feb., 1951.
29. Huebner, R.J., Cole, R.M., Beeman, E.A., Bell, J.A., and Peers, .;.H.:
Herpanoina. Etiolooical studies of a specific infectious disease.
J.A.M.A. 1-?5 626-63J, March, 1951.
30. Cole, R.M., Bell, J.A., Beeman, E.A., and Huebner, R.J.: Studie: :.-
Coxsackie viruses: Observations on epidemiological aspects c` ,:-o:,p A
viruses. Amer. J. Pub. Health 41: 1342-1358, Nov., 1951.
31. Luoto, L., Winn, J.F., and Huebner, R.J.: Q feier studies in Sou-rern
California. XIII. Vaccin3tion of dairy cattle against Q fever.
Amer. J. Hyg. 55: 19G-202,.March, 1952.
32. Reeman. F_..q., Huebner, R.J., and Cole, R.M.: Studies of Coxsackie viruses.
i Ar.c)ratrlrv ;%cnortr, c,f Groun A viruses. Amer. J. Hvc.
Jan., 1952.
3J. Beeman,E.A., and Huebner, R.J.: Evaluation of serological metr,ccs for
demonstrating antiDody respDnses to Group A Coxsackie (Herpancina)
viruses. J. Im-nun. 63: 663-67z, June, 1952.
Peers, J.H., Ransom, S.E., and Huebner, R.J.: The patholgic char._es cro-
duce~ in chick embryos by yolk sac inoculation of Croup A Coxsa:-.ie
virus. J. Exptl. Med. 95: 17-26, July, 1952.
35. Briefs, A., Breese, S.S., Warren, J., and Huebner, R.J.: Physica: :ronerties
of two Group A Coxsackie (Herpangina) viruses when propaga-e-- ecgs and
mice as determined by ultracentrifugation and eiectron microsc:cv.
J. 5act. 61: 237-246, Aug., 1952.
. Huebner, R.J., Beeman, E.A.., Cole, R.M., Beigelman, P.M., and Be!I. J.r+.:
" 6
The importance of Coxsackie viruses in human disease, particular!y
herpangina and epidernic pleurodynia. New Eng. J. Med. 2»7 24z-2=6 (No. 7),
285-289 (No. 8), Aug., 1952. ~
37. Beeman, E.A., Cole, R.M., and Huebner, R.J.: Studies in man of neu'ralizinc
antibodies against Group A Cexsackie (Herpangina) viruses. F-ev-_, !ence ot
antibodies in-a community in 1949 and F950.- Am°r.-J.-Hyg. %-2J-,-
Nov., 1952.
z=
Huebner, R. J. Risser J.A., Bell, J.A., Beeman, E.A., Beioelmar,. :..., and
Strong, J.C.: Epidemic pleurodynia in Texas. Study of 22 cases. New Eng.
I 1,..J 7/ o. ') A 7_77A c..1. ~ o"
65:0C _1 1 c
C T R 11"I N 0 11022, '~

Robert J. Huebner, Publications (continued)
39. Rowe, W.P., Huebner, R.J., Gilmore, L.K., Parrott, R.H., and Wart, T.G.:
Isolation of a cytopathogenic agent from human adenoids uncerc;;ing spon-
taneous degeneration in tissue culture. Proc. Soc. Exp. Biol. Med. 84:
570-573, 195:~.
40. Huebner, R.J., Rowe, W.P., Ward, T.G., Parrott, R.H., and Bell, J.A..:
Adenoidal-pharyngeal-conjunctival agents. A newly recognized croup of
common viruses of the respiratory system. New Eng. J. Med. 2 5!: 1077-
1086, Dec., 1954.
41. Parrott, R.H., Rowe, W.P., Huebner, R.J., Bernton, H.W., and McCullough, N.M.:
Outbreak of febrile pharyngitis and conjunctivitis associatee wi-h
type 3 adenoidal-pharyngeal-conjunctival virus infection. hew Eng. J. Med.
251: 1087-1090, Dec., 1954.
42. Parrott, R.H., Wolf, S.I., Nudelman, J., Naiden, E., Huebner, R.:., Rice,
E.C., and McCullouch, N.B.: Clinical and laboratory differer.-i:Tion be-
tween herpangina and infectious (Herpetic) gingivosto^iatitis. Pediatrics
14: 122-129, Aug., 1954.
43. ParrotT, R.H., Huebner, R.J., McCullougn, N.M., Wolf, S.I., anc Naiden, E.:
The hospital as a factor in assessing the occurrence of Coxsac.:ie viruses
in various illness groups. I. Children from the outpatier.- ceoartment
and various hospital wards. Pediatrics 15: 255-263, March, 1:=5.
44. Huebner, P,.J.: Coxsackie-viral infections. Herpangina and epice^ic
pleurodynia. Cecil 6 Loeb Textbook of Medicine, 9Th Ed., 69-7a, 1955.
47. IaAe'n.)TO, Il.ln.. LynT, K.N., howe, w.r., hlueoner, n..J.. L3ei i , J.r.., rlei f in,
G.W., and Davis, D.J.: Primary isolation of influenzA A, B, :.^.d C viruses
in m:tnkey kidney Tissue cultures. Proc. Soc. Exp. Biol. Mec. °O: 308-
311, 1955.
46. Bell, J.A., Rowe, Y.P., Enaler, J.I., Parrott, R.H., and Huet-e-, ..J..
Pharyngoconj;;r.cTival fever. Epidemiologicai studies Cf a re=e-'fy recos-
nized disease enti7y. J.A.M.A. 157: I0E3-1092, March, 1955.
47. Rowe, W.P., Huebner, R.J., Hartley, J.W., Ward, T.G.. and Parrc-',
Studies of the zdenoidal-ph3ryngeal-conjunctival (AP--) grouC cf viruses.
ATer. J. Hyg. 6!: 197-21E, March, 1955.
48. Ward, T.G., Huebner, R.J., RoNe, W.P., Ryan, R.W., and EvII, J.A.: Pro-
duction of pharyngoconjunctival fever in human volunteers inoculated with
APC viruses. Sc:ence 122: 1086-1087, Dec., 1955.
49. Huebner, R.J., Bell, ,l.A., Rowe, W.P., Ward, T.G., Suskinc, R.G., rzrtley,
J.W., and Paffenbaroer, R.S.,Jr.: Studies of the adenoidal-cnaryneeal-
conjunctival vaccines in volunteers. J.A.M.A. 159: 986-989, frov., 1955.
50. Rowe, h'.P Hartley, J.K., and Huebner, R.J.: Additional seroryces of the._
APC virus group. Proc. Soc. Exp. Biol. Med. 91: 260-262,
51. Hartley, J.W., Huecner, R.J., and Rowe, W'.P.: Serial propacetior of adeno-
viruses (APC) in monkey kidney tissue cultures. Froc. Sc:. Ex;,. Siol. Ye:,.
92: 667-669, 1956.
65100 6:2C
C TR H N 0 11022.6

Robert J. huebner, Publications (conTinued)
52. Cockburn, T.A., Rowe, W.P., and Huebner, R.J.: Relationship c. ~-e 1951
Greeley, Colorado, outbreak of conjunctivitis and pharyngitis -_
type 3 APC virus infection. Amer. J. Hyg. 63: 250-253, 1956.
53. Rowe, W.P., and Huebner, R.J.: Present knowledge of the clinica; sicnifi-
cance of the adenoidal-pharyngeal-conjunctival group ef viruse:.
Amer. J. Trop. Med. and Hyg. 1: 453-460, 1956.
54. Enders, J.F., Bell, J.A., Dingle, J.H., Francis, T.,Jr., Hillema^, u.p.,
Huebner, R.J., and Payne, A.M.: "Adenoviruses" croup name prc:csec for
new respiratory-tract viruses. Science 124: 119-120, July, 19;c.
55. Bell, J.A., Ward, T.G., Huebner, R.J., Rowe, W.P., Suskind, P..C., _°...
Paffenbarger, R.S.,Jr.: Studies of adenoviruses (APC) in vol_-.-=_e-s.
Amer. J. Pub. Health 46: 1130-1146, Sept., 1956.
56. Rowe, W.P., Seal, J.R., Huebner, R.J., Nhiteside, J.E., Woolric.:e. =.L.,
and Turner, H.C.: A study of the role of adenoviruses in ac.:-, -e_-
piratory infections in a Navy recruit population. Amer. J. ry;. 6
211-219, 1956. (Sept.)
57. Bell, J.A., Hantover, M.J., Huebner, R.J., and Loosli, C.G.: Effic:!cy of
trivzlent adenovirus (APC) vaccine in naval recruits. J.A.M.4. '^I:
~
1521-1525, Aug., 1956. --
58. Eaqle. U., Hmbel, K.. Rowe, W.P., and Huebner, R.J.: Viral susce:-ibility
.`. e hum a,^, ._rcir.c,_ cell (strain KE). Proc. Soc. Exp. Eiol. v-=. °I
361-364 , 1956.
59. Rowe, W.P., Hartley, J.W., Waterman, S., Turner, H.C., and Huebner, n.J.:
Cytopayhooenic acen- resembling human salivary gland virus re__ve,ed
from tissue cultures of human adenoids. Proc. Soc. Exp. 6io;. %'?_. 92:
418-424, 1956.
60. Smith, R.R., Huebner, R.J., Rowe, W.P., SchatTen, W.E., and Tr. _., ~.G.:
Studies on the use of viruses in the treatment of carcinoma c, -'e
cervix. Cancer 9: 1211-1218, Nov.-Dec., 1956.
61. HueSner, R.J., and Rowe, W.P.: Adenoviruses as etiologic aoenTs ir con-
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52. Rowe, W.P., Huebner, P.J., and °ell, J.A.: Definition and outline of con-
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63. Hueoner, R.J., Bell, J.A., and Rowe, W'.P.: The imoortance of eceneyiruses
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the N.Y. Aced. Sci. 5: 393-402, Dec., 1957.
64. Huebner, R.J.: The virologist's dilemma. Ann. N.Y. Acad. Sci. =
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65. Huebner, R.J.: ImplicaTions of recent viral studies. Pub. Heal'^ =~eaorts
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C T R HIN 0 1102 S-4

nvvrf I j. r,ueuner, ruui Ice TlonS tCO.'1TInUeO)
66. Suskind, R.G., Huebner, R.J., Rowe, W.P., and Love, P,.: Viral acer-s
oncolytic for human tumors in heterologous host. 0ncotytic effecT of
Coxsackie B viruses. Proc. Soc. Exp. Biol. Med. 94: 309-318, 1957.
67. Hartley, J.W., Rowe, W.P., and Huebner, R.J.: Serial propagation cf the
guinea pig salivary oland virus in tissue culture. Proc. Soc. Exp.
Biol. Med. 96: 281-285, 1957.
68. Bell, J.A., Ward, T.G., Kapikian, A.Z., Shelokov, A., Reichelderfer, 7.E.,
and Huebner, R.J.: Artificially induced Asian influenza in vaccinated
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69. Huebner, P..J.: Illnesses due to adenoviruses. Symposium, "Viruses:
Current advances with clinical applications," Modern Medicine,
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70. Rowe, W.P., Hertley, J.W., and Huebner, R.J.: Serotype composi'i=r cf the
adenovirus group. Proc. Soc. Exp. Biol. Med. 97: 465-470, I::-1.
71. Halonen, P., Huebner, R.J., and Turner, H.C.: Preparation of E.r.C ccmple-
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cation by fluorocarbon. Proc. Soc. Exp. Bi.ol. Med. 97: 530-53:, 1953.
72. H!:Ionen, P., Rosen, L., and Huebner, P..J.: Typing of ECHO viruses --v a
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73. CramSlet' F:.G.. RnsPn. L.. P:,rr;)tt. R.H.. Rol I .I ~ H-lphnP,. p...1 An~+
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newly recognizec ECriD virus. Pediatrics 21: No. 2, 158-177, Fe:., :958.
74. Rosen, L., J:)hnson, J.H., iiuebner, R.J., and Bell, J.A.: 0bserva-~i:r,s on
a newly recooni:ed ECH~ virus and a description of an outbreaK in, a
nursery. Amer. J. Hyg. 67: 3^0-310, May, 1958.
75. Chanock, R.M., Parrott, R.H., Cook, K., Andrews, B.E., Bell, j.A.,
Reichelderfer, i., Kapiki3n, A.Z., Mastrotz, F.M., and Huebner, =.J.:
Newly recognized myxoviruses from children with respiratory cise=se.
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76. Chanock, R.M., Parrott, R.H., 6ell, J.A., Rowe, W.P., and Huebner, =..J.:
New viruses observed in children with respiratory diseases. Puc. Health
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77. Huebner, R.J.: Clinical importance of "new" respiratory viruses. F!:' st-
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78. Huebner, R.J., Rowe, W.P., and Chanock, R.M.: Newly recognized res,,iratory
tract viruses. Ann. Rev. ef Micro. 12: 49-76, 1953.
79. Reicnelderfer, T.E., Chanock, R.M., Craichead, J.E., Huebner, R..'.,
Turner, H.C., anC J°^ies, W.: Infection of human volunteers wi,!~ -ype 2
hemadscrption virus. Science 12?: 779-780, Oct., 195°.
6=1 11 Z, 61 22
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