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PUBLISHED ARTICLES Page Five Michael J. Brennan, M.D. 36. M.J. Brennan. Micnigan's 3000'Candidates for Practical Cancer Chemotherapy. Journal of the Michigan State Medical Society, Vol. 62, pp. 398-400, April 1963. 37. R.W. Talley, M.J. Brennan, V.K. Vaitkevicius and V.L. Recke:t. Comparison of 2,17 Dimethyl Testosterone and Fluoxymesterone in Metastatic Breast Cancer: Non-Progression - An Index of Tumor Therapy Evaluation. Cancer, Vol. 16, No. 4, pp. 440-443, April 1963. 38. M.J. Brennan, R.W. Talley, E.H. Drake, V.K. Vaitkevicius, A.K. Pozanski, and B.E. Brush. 5-Fluorouracil Treatment in Liver Metastases by Continuous Hepatic Artery Infusion Via the Courand Catheter: Results and suitability for intensive post surgical adjuvant chemotheraoy. Annals of Surgery, Vol. 158, No. 3, pp. 405-519, Septemcer 1963. 39. M.J. Brennan. A Survery of Progress in Chemotherapy. Rhode ?sland Medical Journal, Vol. XLVI, No. 11, 585-589, November 1963. 40. M.J. Brennan, J.W. Kebuck, R.W. Talley. Sequential Observations in Vivo of Leukocytic :nteractions with Autochtonous and Ho.:,oloccus Cancer Cells in Mar.. Proceedings of American Society of Hemato,ogy, pp. 792, December 41. M.J. Brennan, J.W. Pebuck and R.W. Talley. Histochemical Stcd-es of the Transfer of Cytoplasmic Components from Mesenchymal to Neoplastic Cells in Vivo in Man. Proceedings of American Assoc=a- tion for Cancer Research, No. 5, p. 7, March 1964. 42. R.W. Talley and M.J. Brennan. Correlative Analysis of Pre- and Post- Treatment Urinary Calcium and Creatinine Excretions in Post-Yenoaausal Breast Cancer Patients. Proceedings of American Association for Cancer Research, No. 5, 62, "'arch 1964. 43. J.W. Rebuck, M.J. Brennan and J.A. Hall. Troahocytic Leukocytic Function in the Resconses of Inflammation and to Autochthonous and Homologous Cancer Ce'ls in Man. Federation Proceedings, Vol. 2?, No. 2, p. 486, March-A.-,ri1 1964. CTR HN 010949

PUBLISHED AR'ICL ES Page Six Michael J. Brennan, M.D. 44. V.K. Vaitkevicius, M. Sugimoto, M.L. Reed and M.J. Brennan. Autolooous Transplantation of Enzymatically Prepared and Freeze-Preserved Human Tumors. Cancer, Vol. 17, No. 5, pp. 666-673, May 1964. 45. R.W. Talley, M.J. Brennan, V.K. Vaitkevicius, E.L. San Diego, !!.L. Reed and G.A. Leighton. Comparison of 6a-Methyl-9o-Fluoro-17- Acetoxy-21-Deoxy-Prednisolone with Fluoxymesterone and Methyl- prednisolone in Treatment of Metastatic Breast Cancer. Cancer, Vol. 17, No. 8, F:. 1063-1066, August 1964. 46. J. Keith Welborn, M.J. Brennan and J.C. Hathaway, Jr. Acute =ibrino- lysis with Gastric Carcinoma. American Journal of Surgery, Vol. 108, No. 3, pp. 344-348, September 1964. 47. R.W. Talley, A.K. Pozanski, J.H. Heslin and M.J. Brennan. Laminograrrs of the Thorotrast-Ooacified Liver in Evaluation of Chemotherapy for Metastatic Cancer. Cancer, Vol. 17, No. 9, pp. 1214-1219, September 1964. 48. M.J. Brennan, R.ti. 7alley, E.L. San Diego, J.H. Burrows, R.M. C'Bryan, V.K. Vaitkevicius, and S. Horeglad. Critical Analysis of 594 Cancer Patients Treated with 5-Fluorouracil. Chemotherapy of Cancer, P1. A. Plattner, Editor, ?roc. of an International Symposium. Lugano, Switzerland, Elsevier Publishing Company, 1964. 49. J.W. Rebuck, M.J. °_rennan, J.A. Hall and C.L. Barth. Leuccc•. : Trophism for Inflacration and Autochthonous and Homologous ~:.Tcr Cells. Journal of tne Reticuloendothelial Society 1:450-16?, December 1964. 50. Michael J. Brennan, J.W. Rebuck and R.W. Talley. Skin Window Studies of Autochthonous ano Homologous Cancer Cells in Man. Proc. Jam.es Ewing Society, April 1965. 51. V.K. Vaitkevicius, `". Sugimoto, M.L. Reed and M.J. Brennan. E=`ect of Acute Tissue Injury on Transplantability of Autologous Human Cancer. Cancer 18:565-670, June 1965. 52. Michael J. Brennan. Cytological Diagnosis. Ann. Int. M.ed. 63:1155- 1159, December 196E. ` C ~`R MIN 010950

PUBLISHED ART.C:ES Page Seven Michael J. Brennan, M.D. 53. E.L. Moorhead, II, !".J. Brennan, J.R. Caldwell and W.C. Averill. Pheochromocytoma: A Familial Tumor. Henry Ford Hospital Meoical Bulletin 13:467-478, December 1965. 54. Michael J. Brennan. Indices of Response to Breast Cancer Therapy. Clinical Evaluation in Breast Cancer, pp. 141-174, Editors: J.L. Haywaro and R.D. oulorook. Acaaemic Press, London, 1966. 55. Michael J. Brennan. Chemotherapy of Solid Tumors. Modern Treatment, Vol. 3, No. 4:i9i-c39, July 1966. 56. Michael J. Brennan. Medicine and the New Programs. The Linacre Quarterly, Vol. 33, 'ro. 4:375-380, November 1966. 57. M.J. Brennan, T, Cole, and J. Singley. A Unique Hyperfine ESR Signal in Mouse Nerolasms Analyzed by Computer Simulation. Proc. Soc., Vol. 123, N'o. 3:715-718, December 1966. 58. Charles S. Eby, "".icnael J. Brennan and Gerald Fine. Lymphancosarcoma: A Lethal Complica:ion of Chronic Lymphedema. Arch. Surg. 94:223-230, February 1967. 59. Michael J. Brennan. The Value of Hormonal and Chemotheraoeutic Treatment for Acvan.ced Breast Cancer. First Tenovus Sv^:cosiuT.: Factors Influencir: ?rognosis of Breast Cancer. Welsh 111ationai Scnccl of 4edicine, University of Wales, April 1967. 60. Michael J. Brennan and Robert W. Talley. Implications of Treatment Sequence Effects cn Responsiveness to 5-Fluorouracil and Cytoxan. Current Conceots in 5reast Cancer, p. 225, Editors: Albert Segaloff, Kennetn K. Meyers an^ Se a DeBaicey. Williams & Wilkins Co^pany, Baltimore, 1967. 61. Michael J. Brennan. Comparison of Cumulative Survival Functions for Breast Cancer Series Differing in Treatment Plan. Current Concepts in Breast Cancer, p. 208, Editors: Albert Segaloff, Kennetn K. Meyers and SeTma DeBaKey. riilliams & Wilkins Company, Baltimore, 1967. 62. Micnael J. Brennan. The Biology of Antimetabolites and Chemotherapeutic Agents. Current ConceDts in Breast Cancer, p. 250, Editors: Albert Secalc`f, Kenne:r, .i?Ie_ver~ anc ~ei ::a eoaKey, hil l iams 's Wil ~cins Co^oany, Balti;-crP, 1957. CT\ ti • \ \ ` 0.L. S-!' 9E-j1

PUBLISHED ART::__S Page Eignt Michael J. Brennan, "".O. 63. Michael J. Brennar,. Host-Cell/Tumor-Cell Interactions Infiuencing Establishment of Metastases: Clinical and Experimental Observations. Twenty-Third Annual Symposium on Fundamental Cancer Researcn, !".D. Anderson Hospital and Tumor Institute: The Proliferation ar.~ Spread of Neoplastic Cells, pp. 607-613. WiliT-ans & wiiv.ins t_omoany, Baltimore, 968. 64. T.F. Mancuso and u.J. Brennan. Epidemiological Considerations of Cancer of the Gail:ladder, Bile Ducts and Salivary Glanas i., t~e Rubber Industry. '.curnal of Occupational Medicine, Vol. 12, `+o. 9, p. 333, Septembe- '970. 65. M.J. Brennan. The ~ancer Gestalt. Geriatrics, Vol. 25, ';o. 10, pp. 96-101, Octooer 1970. 66. Dan H. Moore, Jesse Charney, Bernhard Kramarsky, Ettienne Y. Lasfargues Nurul Sarkar, Micnael J. Brennan, J.H. Burrows, Satyavati 'j. Sirsat, J.C. Paymaster anc A.B.- Vaidya. Search for a Human Breast Cancer Virus. Nature, Vol. 229, pp. 611-614, February 1971. 67. M.J. Brennan and ,;.~. Burrows. Che^~therapy for Gastric, Esochageal, and Pancreatic Cancer. In: 0ncoloov 1970: Diaanosis ano Vanagement of Cancer: Specific Sites (Proceedinas of the 10th International Cancer Congress, 'Jc;ume IV), Year Book Publishers, Inc., C^icaco, 1971, pp. 127-136. 68. M.J. Brennan. =d'.:•;ant Therapy ., E.re?st Cancer. . Cnc;;l--' 1970: Experimenta. Cancer Therapy. (Proceedings of the~ nternational Cancer Congress, Volume II), Year Book Publishers, Inc., Chicago, 1971, pp. 503-515. 69. M.J. Brennan and C.A. McMahan. Cancer of the Breast. Cancer ~edicine. Editors: James F. '-olland, and Emil Frei, IIi. Lea-Feoiger, Philadelphia, pp. 1769-1788, 1973. 70. M.J. Brennan. Cor:'cos*.eroids in the Treatment of Solic Tumcrs. In: Medical Clinics of North America. Editor: Daniel L. Azarnor`. Vol. 57, No. 5, pp. 1225-1239, Septemter 1973. 71. M.J. Brennan, R.D. Bulbrook, N. Desnpande, D.Y. Wang, and J.:. wayward. Urinary and Plasma :.ncrogens in Benign Breast Disease. Lancet, May 19, 1973, pp. 1076-1C7:. CTR MN 01 09ab2

Published Articles Page Nine Michael J. Brennan, M.D. 72. H.D. Soule, J. Vazquez, A. Long, S. Albert and M. Brennan. r Human Cell Line from a Pleural Effusion Derived from a Breast Carcincma. Journal of the National Cancer Instifute, November 1973, Vcl. ~, No. 5, pp. 1409-1416. 73. Chopra, H., Ebert, P., Woodside, N., Kvedar, J., Albert, S. and Brennan, M. Electron Microscopic Detection of Simiantype Virus Particles in Human Milk. Nature New Biology, 243:159-160, 1~73. 74. Gerwin, Brenda I, Ebert Paul S., ChoDra, Harish C., Smith, G., Kvedar, John P., Albert, Sam and Brennan, Michael J. DNA Poiy^~erase Activities of Human Milk. Science 180:198-201, 1973. 75. Brennan, M.J., Wang, D.Y. and Hayward, J.L. Urinary and Plasma Andro- gens in Benign Breast Disease: Possible Relation to Breast Cancer. Lancet 1:1076-1079, May 19, 1973. 76. Lynch, H.T., Guirgis, H., Albert, S. and Brennan, M. Familia' 3reast Cancer in a Normal Population. Cancer 34:2080-2086, 1974. 77. Rich, M.A., Furmanski, P., McCormick, J.J., McGrath, C., Soule, H. and Brennan, M.J. The In Vitro Propagation of a Candidate Human Breast Cancer Virus--Status Report. Proc. Breast Cancer Task Force Conference, p. 48, 1974. 78. Henry T. Lynch, Hoda A. Guirgis, Samuel Albert, Michael Bren^.a7~, Jane Lynch, Carol Kraft, Dennis Pocekay, Christopher Vaughns a^.c Arnold Kaplan. Familial Association of Carcinoma of the Breast and Ovary. Surgery, Gynecology & Obstetrics, May 1974, Vol. 133, p. 717-724. 79. Brennan, M.J. Endccrinology in Cancer of the Breast: Status anc Prospects. American Journal of Clinical Pathology, 64:797-8C9, 1975. 80. Rich, M.A., Das, M.R., Furmanski, P., McCormick, J.J., McGrath, C.M., Russo, J.P., Soule, H.D. and Brennan, M.J. Studies of the Role cf Viruses in Human Breast Cancer. Proc. Breast Cancer Task Force Conf. p. 55-56, 1975. CTR { •\~• •J• 1V` 9SY

PUBLISHED ARTICLES Page Ten Michael J. Brennan, M.D. 81. Singhakowinta, A., !?ohindra, R., Brooks, S.C., Vaitkevicius, '/.K., Brennan, M.J. Clinical Correlation of Endocrine Therapy and Estrogen Receptor. Estrooen Receptors in Human Breast Cancer. -~_- ess, .:-5, WL McGuire, PP Carbone, o meTT~r New YorK, Raven ~r ~ pp. 131-155. 82. R.R. Gala, A. Sinchakowinta and M.J. Brennan. Studies of Prolactin In Human Serum, Urine, and Milkl. Prolactin Activity in 'r'L;mar. Lh-ine and Milk. Horrone Research 6:310-320, 1975. 83. Brennan, M.J. Murir.e and Rat Ma^:mary Tumors as "bdels for t`,e Immunological Study of Human Breast Cancer. Cancer Researcn 36: 728-733, February 1976. 84. M.J. Brennan and C.A. McMahan. Analysis of Recent Breast Cancer Treatment Studiesl. The Phvsiopatholoov of Cancer, Vol. 2, Diagnosis, Treatment,--Frevention, pp. 12-M, rger, Basel, 1976. 85. Clifford W. Welsh, Gloria Calaf De Iturri, Michael J. Brennan. DNA Synthesis of Human, Mouse, and Rat Mammary Carcinomas In Vitro. Influence of Insulin and Prolactin: Cancer, Vol. 38, No. 3, September 1976, pp. 1272-1281. 86. Brennan, M.J. Tru:h versus Data. Medical and Pediatric Oncolcgy, 3(2):199-205, 1977. 87. Brennan, M.J. Lac_a.ion and the Breast Cancer Process. Lzc_a_ion, A Comorehensive Trea t ise. Vol. IV The Mammary Gland, Human Lactation, Milk Syntnesis. pp. 313-336, New York, Academic resh s -T-978. 88. Russo, J., Fine, G., Husain, M., Krickstein, H., Robbins, T., Rosenberg, B., Park, Y., Brennan, M.J. and Rich, M.A. Analysis of Recurrence of Infiltrating Ductal Carcinomas Containing Tubular and Cribriform Patterns. Proc. Am. Assoc. Cancer Res. Vol. 20, 660, March 1979. 89 Weigand, R.A., Isenberg, W.M. and Brennan, M.J. Elastosis as a Prognostic Indicator in Human Breast Cancers. Proc. Am. Assoc. Cancer Res. Vol. 20, 577, March 1979. 90. Rich, M.A., Brennan, M.J. , and the Scientific Patholoyy and Sur~ical Associates of tne "''-F ?reast Cancer Prognostic Study. The Breast Cancer Prognostic Program: A Study of the Metastatic Process (BCPS publication numoer 7) Proc. of XI Meeting on Mammary Cancer in Experimental Animals and Man, 1979 !,_, tr Rt t F "t 0.k. 09E54

PUBLISHED ARTICLES Page Eleven Michael J. Brennan, M.D. 91. Rich, M.A., Brennan, M.J., and the Scientific, Pathology, and Surgical Associates of the MCF Breast Cancer Prognostic Study. An anlysis of the Metastatic Potential of Human Breast Cancers: The Breast Cancer Prognostic Study (BCPS publication number 11) Proc. of the 1979 Symposium Production by Malignant Tissue of Tumors, Antigens, Hormones, and Enzymes. 92. Brennan, M.J., Rich, M.A., and the Scientific, Pathology, and Surgical Associates of the MCF Breast Cancer Prognostic Study. The Breast Cancer Prognostic Study: Analyzing the Metastatic Potential of Human Breast Cancers (BCPS publication number 10). Proc. of 1979 Mty. of Soc. of Surgical Oncology, (1979). 93. Rich, M.A., Brennan, M.J., and the Scientific, Pathology, and Surgical Associates of the MCF Breast Cancer Prognostic Study. Analyzing the Metastatic Potential of Human Breast Cancers: A Prognostic Study (BCPS publication number 12). Proc. of OLAC Second Ann. Cancer Res. Conf. (1979). 94. Rich, M.A., Brennan, M.J., and the Scientific, Pathology, and Surgical Associates of the Michigan Cancer Foundation Breast Cancer Procnostic Study. The Assessments of Metasta- tic Potential in Human Breast Cancer: A Prognostic Study (BCPS publication number 16). Proc. of the First Intl. Congress on Hormones and Cancer, (1979). 95. Furmanski, P., Rucczynski, A.B., Mortensen, R.F., Brennan, and Rich, M.A., anc the Breast Cancer Prognostic Study Clinica' and Pathology Assc:iates. An Analysis of the Metastatic Pro.-ress of Human Breast Cancers: The Breast Cancer Prognostic Study (BCPS publication number 17). Proc. of the 6th Chicago Cancer Symposium "Tumor Progress," 1920 96. Weigand, R.A., Isenaerg, W.M., Brennan, M.J., and the Breast Cancer Prognostic Study Associates. Elastosis as a Prognostic Indicator in Human Breast Cancers (BCPS publication number 20). Proc. Am. Assoc. Cancer Res. 20:143, (1979). 97. Russo, J., Fine, G., Husain, M., Krickstein, H., Robbins, T., Rosenberg, B., Park, Y., Brennan, M., Rich, M., and Soule, H.D. Analysis of Recurrence of Infiltrating Ductal Carcinomas Con- taining Tubular and Cribriform Patterns (BCPS publication number 21). Proc. of Am. Assoc. Cancer Res. 20:164, (1979). C T' M N 0 10 9 Ej E__ $*

PUBLISHED HRTICLES Pace Twelve Michael J. Brennan, M.D. , 98. Wilson, G.S., Rich, M.A., Brennan, M.J., and the Scientific Associates of the Michigan Cancer Foundation Breast Cancer Prognostic Study. Value of Bone Scan in Preoperative Clinical Staging of Breast Cancer. Archives of Surcerv, 115:415-419, 1980. 99. Russo, J., Fine, G., Krickstein, H., Husain, M., Robbins, T., Rosenberg, B., Brooks, S., Miller, J., Brennan, M.J., Rich, M.:,., and the Michigan Cancer Foundation Breast Cancer Prognostic S:uay Associates. Relationship Between Mitotic Activity and Recurrence of Breast Tumors (C-?S publication number 31). Proc. Am. Assoc. Cancer Res. , 1920. 100. Park, Y., Russo, J., Furmanski, P., Horowitz, S.B., Brennan, "1., Rich, M.A., and the Breast Cancer Prognostic Study Patholoay and Surgery Associates. Interactive Relationships Among Histoloeical, Nuclear and Mitotic Grades for the Prediction of Breast Cancer Recurrence (BCPS ouolication number 33). Proc. Am. Assoc. Cancer Res., 1980. C 1•R 1 tF`t 0 109~t6