Tobacco Documents Online

Personal Information NalIle: Business Address: Business Phone: Home Address: Home Phone: Social Security Number: Spouse's Name: Raymond L. Erikson Biological Laboratories Harvard University 16 Divinity Avenue Cambridge, MA 02138 (617) 495-5386 (617) 495-0681 176 Hancock Street Cambridge, MA 02139 (617) 491-7255 396-34-7610 Donna Erikson

Birthdate: Raymond L. Erikson American Cancer Society Professor of Cellular and Developmental Biology Harvard University January 24, 1936 - Eagle, Wisconsin, USA Education: University of Wisconsin, Madison, Wisconsin University of Wisconsin, Madison, Wisconsin University of Wisconsin, Madison, Wisconsin USPHS Postdoctoral Fellow, University of Colorado Medical School, Denver, Colorado B.S. 1958 M.S. 1961 Ph.D. 1963 1963-1965 Academic Appointments: American Cancer Society Research Professor Harvard University, Cambridge, Massachusetts Professor of Cellular and Developmental Biology Harvard University, Cambridge, Massachusetts From Assistant Professor to Professor of Pathology University of Colorado Medical School, Denver, Colorado 1983-date 1982-date 1965-1982 Professional Experience: Member, American Cancer Society Advisory Committee on Personnel for Research Advisory Committee on Microbiology & Virology Member, Awards Assembly, General Motors Cancer Research Foundation Member, Alfred P. Sloan Jr. Prize Selection Committee American Business Cancer Research Foundation, Inc. Award Member, NIt-I Experimental Virology Study Section American Cancer Society Scholar, Imperial Cancer Research Fund, London, England 1986-1990 1983-1986 1986-1990 1985-1987 1981-1986 1975-1978 1972-1973 Honors and Awards: Hammer Prize for Cancer Research Alfred P. Sloan, Jr. Prize, General Motors Cancer Research Foundation Award Association of American Medical Colleges Award for Distinguished Research in Biomedical Sciences Robert Koch Prize, The Robert Koch-Stiftung e. V. Albert Lasker Basic Medical Research Award, The Albert and Mary Lasker Foundation Papanicolaou Award for Scientific Achievement in Cancer Research 1984 1983 1982 1982 1982 1980 Professional and Honorary Societies: Amer. Society of Biological Chemists Amer. Society for Microbiology National Academy of Sciences Amer. Academy of Arts & Sciences

BIBLIOGRAPHY (Partial list - total number of publications is 116) Alcorta, D., Crews, C.M., Sweet, L.J., Bankston, L., Jones, S.W. and Erikson, R.L.: Sequence and expression of chicken and mouse rsk: homologs ofXenopus laevis ribosomal $6 kinase. Mol. Cell. Biol., 9:3850-3859, 1989. Martin-Perez, J., Bar-Zvi, D., Branton, D. and Erikson, R.L.: Transformation by Rous sarcoma virus induces clathrin heavy chain phosphorylation. J. Cell Biol., 109:577-584, 1989. Ingebritsen, T.S., Lewis, S.K., Ingebritsen, V.M., Jena, B.P., Hiryanna, K.T., Jones, S.W. and Erikson, R.L.: Properties and regulation of protein tyrosine phosphatases. Adv. Prot. Phosphatases, 5: 121-147, 1989. Sweet, L.J., Alcorta, D., Jones, S.W., Erikson, E. and Erikson, R.L.: Identification of a mitogen-responsive ribosomal protein $6 kinase in chicken embryo fibroblasts, pp9Orsk: A homolog of Xenopus $6 kinase II. Mol. Cell. Biol., 10:2413-2417, 1990. Chernoff, J., Schievella, A.R., Jost, C.A., Erikson, R.L. and Neel, B.G.: Cloning of a cDNA for a major human protein-tyrosine-phosphatase. Proc. Natl. Acad. Sci. USA, 87:2735-2739, 1990. Vik, T.A., Sweet, L.J. and Erikson, R.L.: Coinfection of insect ceils with recombinant baculovirus expressing pp60v-src results in the activation of a serine-specific protein kinase, pp90rsk. Proc. Natl. Acad. Sci. USA, 87:2685-2689, 1990. Biemann, H.-P. and Erikson, R.L.: Abnormal protein kinase C down regulation and reduced phospho.substrate levels in non-phorbol ester-responsive 3T3-TNR9 cells. Mol. Cell. Biol., 10:2122-2132, 1990. • Sweet, L.J., Alcorta, D.A. and Erikson, R.L.: Two distinct enzymes contribute to biphasic $6 phosphorylation in serum-stimulated chicken embryo fibroblasts. Mol. Cell. Biol., 10:2787- 2792, 1990. Erikson, E., Mailer, J.L. and Erikson, R.L.: Ribosomal $6 kinase II (rsk) in Methods in Enzymology, Abelson, J.N. and Simon, M.I. (Eds-in-Chief). Vol. 200, "Protein Phosphorylation" (Vol. eds., Hunter, T. and Sefton, B.M.), Academic Press, Orlando, FL (pp. 252-268, 1991). Ottilie, S., Chernoff, J., Hannig, G., Hoffman, C.S. and Erikson, R.L.: A fission yeast gene encoding a protein with features of protein tyrosine phosphatases. Proc. Natl. Acad. Sci. USA 88:3455-3459, 1991. Xie, W., Chipman, J.G., Robertson, D.L., Erikson, R.L. and Simmons, D.L.: Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl. Acad. Sci. USA, 88:2692-2696, 1991. Erikson, R.L.: Structure, expression and regulation of protein kinases involved in the phosphorylation of ribosomal protein $6. J. Biol. Chem., 266:6007-6010, 1991. Blenis, J., Chung, J., Erikson, E., Alcorta, D.A. and Erikson, R.L.: Distinct mechanisms for the activation of the RSK kinases/MAP2 ldnase/pp90rsl~ and pp70-S6 kinase signaling systems are indicated by inhibition of protein synthesis. Cell Growth and Differentiation, 2:279-285, 1991. Crews, C.M, Alessandrini, A. and Erikson, R.L.: Mouse Erk-1 gene product is a serine/threonine protein kinase that has the potential to phosphorylate tyrosine. Proc. Natl. Acad. Sci. USA, 88:8845-8849, 1991. Crews, C.M., Alessandrini, A. and Erikson, R.L.: Erks: Their fifteen minuteshas arrived. Cell Growth and Differentiation, 3:135-142, 1992. Ottilie, S., Chernoff, J., Hannig, G., Hoffman, C.S. and Erikson, R.L.: The fission yeast genes pypl+ and pyp2+ encode protein tyrosine phosphatases that regulate mitosis (submitted, 1992). Alessandrini, A., Crews, C.M. and Erikson, R.L.: Identification of a phorbol ester-stimulated protein tyrosine and threonine kinase that phosphorylates and activates the Erkl gene product (submitted, 1992).

Crews, C.M. and Erikson, R.L.: Purification of protein tyrosine/threonine kinase that phosphorylates the Erkl gene product: Relationship to the yeast genes STE7 and byrl (in preparation, 1992). Wang, H-C. R. and Erikson, R.L.: Identification of novel MBP kinases activated in transformed and mitotic cells (in preparation, 1992). Schievella, A.R., Hill, D. and Erikson, R.L.: Protein tyrosine phosphatase 1B is phosphorylated on serine in mitotic cells (in preparation, 1992).