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RICHARD JOHN BING, M.D. • DATE & PLACE OF BIRTH: MARITAL STATUS: PRE-MEDICAL EDUCATION: MEDICAL EDUCATION: INTERNSHIP: RESIDENCY: ADDITIONAL TRAINING: TEACHING APPOINTMENTS: CURRICULUM VITAE October 12, 1909 - Nuremberg, Bavaria (U.S. CITIZEN) Married to Mary A. Whipple - four children. Universities of Vienna, Munich and Berlin, 1929 - 1934. M.D. - University of Munich, 1934. M.D. - University of Bern, Switzerland, 1935. Presbyterian Hospital, New York, 1938 - 1939. Johns Hopkins Hospital, Baltimore, 1942 - 1943. Fellow, Carlsberg Institute, Copenhagen, 1935 - 1936. Fellow, Rockefeller Institute, New York, 1936 - 1937. Instructor in Physiology, Columb ia University, College of Physicians and Surgeons, New York, 1939 - 1941. Instructor in Physiology, New York University, 1941 - 1942. Instructor in Medicine, Johns Hopkins Medical School, Baltimore, 1943 - 1944. Assistant Professor of Surgery and Assistant Surgeon, Johns Hopkins Medical School, 1945 - 1947. Associate Professor of Surgery and Assistant Professor of Medicine, Johns Hopkins Medical School, 1947 - 1951. Professor of Medicine, Professor of Clinical Physiology and Director of Cardiac Clinic, Medical College of Alabama, University of Alabama at Birmingham, 1951 - 1955. - Director, Washin'gLon University -Medical--S-ervice VA Hospital, and Professor of Medicine, Washington University, School of Medicine, St. Louis, 1956 - 1959.

Richard John Bing, M.D. Curriculum Vitae Page 2 TEACHING APPOINTMENTS: Consultant at VA Hospitals, Sepulveda, California, (Continued) Little Rock, Arkansas, and Washington D.C. Professor of Medicine, Chairman, Department of Medicine, Wayne State University, School of Medicine, Detroit, 1959 - 1969. Professor of Medicine, University of Southern California, School of Medicine, Los Angeles, 1969 - present. Director of Experimental Cardiology and Scientific Development, Huntington Memorial Hospital and `Huntington Medical Research Institutes, Pasadena, California, 1969 - present. Visiting Associate, California Institute of Technology, Department of Chemical Engineering, Pasadena, California. HONORS: Harvey Society Lecture (Harvey Lecture), 1956. Honorary M.D., University of Dusseldorf, 1966. Hektoen Silver Medal - Best Scientif ic Exhibit, American Medical Association. Claude Bernard Medal, Montreal. Mitchell Foundation Award, Washington D.C., 1970. Los Angeles County Heart Association Award, 1972. American Heart Association Research Achievement Award, 1974. Honorary Life President, International Study Group for Research in Cardiac Metabolism, 1974. Recipient, Alexander von Humboldt Foundation Award (Senior Fellowship), 1979. Institution of the "Richard Bing Award for the best young investigator in the f ield of heart research" by the International Society for Heart Research. Research Achievement Award, American Heart Association, 1980. Distinguished Scientist Award, American College of Cardiology, 1984. - Lindbergh Research Award, The Charles A. Lindbergh Foundation, 1984. MILITARY SERVICE: Army Medical Corps, Captain 1943 - 1945. Promoted to Lt. Col., U.S. Army.

Richard John Bing, M.D. Curriculum Vitae Page 3 SPECIALTY: Cardiac Physiology and Applied Pharmacology. • Internal Medicine and'Cardiology. MEMBERSHIPS: American'College of Cardiology American College of Physicians American Federation for Clinical Research American Heart Association American Medical Association American Physiological Society American Society for Clinical Investigation American Society of Internal Medicine Association of American Physicians Central Society for Clinical Research Harvey Society Hellenic Society of 'Cardiology - Honorary Member 'International Society of 'Cardiology (Section of Epidemiology and Prevention) International Society for Heart Research Los Angeles'Cardiology Society Los Angeles County Heart Association Society for Experimental Biology and Medicine Southern Society for'Clinical Research Spanish Society of 'Cardiology - Honorary Member Italian Society of Experimental Biology and Physiology - Honorary Member, 1968 Los Angeles Society of Internal Medicine 'Claude Bernard Visiting Professorship, 1969 German Society for Internal Medicine - Corresponding Member Western Association of Physicians Society for Clinical Pharmacology OTHER APPOINTMENTS: Former Editor-in-Chief of the Journal of Molecular and-Cellular Cardiology. Past Editorial Board Member of the American Journal of Cardiology. Editorial Board Member of the Journal of Cardio- vascular Pharmacology. Honorary Life President, American Section of the International Society for Heart Research. Former Vice President, American College of Cardiology. Previous Member of the U.S. Public Health Service, Study Section, etc.

PUBLICATIONS • RICHARD JOHN BING, M.D. Bing, R.J.: The perfusion of whole organs in the Lindbergh Apparatus with fluids containing hemocyanin as respiratory pigment. Science 87:554, 1938. Bing, R.J. and Zucker, M.B.: Renal hypertension produced by amino acid. J. Exper. Med. 74:235, 1941. Bing,R.J., Zucker, M.B. and Perkins, W.: Comparisons between destruction of angio- tonin, hydroxytyramine and tyramine by renal extracts. Proc. Soc. Exper. Biol. Med. 48:372, 1941. Bing, R.J.: Effect of vasoconstrictor substances in shed blood on perfused kidneys. Amer. J. Physiol. 133:21-28, 1941. Bing, R.J.:Formation of hydroxytyramine by extracts of renal cortex and by per- fused kidneys. Amer. J. Physiol. 132:497, 1941. Bing, R.J. and Zucker, M.B.: Formation of pressor amines in kidney. Proc. Soc. Exper. Biol. Med. 46:343, 1941. Bing, R.J.: Etiology of renal failure following crush injuries. Proc. Soc. Exper. Biol. Med. 53:29, 1943. Bing, R.J.: Effect of vitamin A on some renal functions of dog. Amer. J. Physiol. 140 : 240, 1943. Bing, R.J.: Effect of hemoglobin and related pigments on renal functions of normal and acidotic dog. Bull. Johns Hopkins Hosp. 74:161, 1944. Bing, R.J., Thomas, C.B. and_Waples, E.C.: Thee circulation in experimental neu- rogenic hypertension. J. Clin. Invest. 24:513, 1945. Bing, R.J. and Thomas, C.B.: Effect of two diazone derivations, 883 and 933F on normal dogs and on animals with neurogenic and renal hypertension. J. Pharm. & Exper. Therap. 83:21, 1945. Bing, R.J., McNamara, B. and Hopkins, F.H.: Studies on the pharmacology on DDT (2,2 bisparachiorophernyl -1, 1, 1 trichloroethane). The chronic toxicity of DDT in the dog. Bull. Johns Hopkins Hosp. 78:308, 1946. Bing, R.J.: Experimental renal hypertension and amino acid metabolism in the kidney. A monograph. New York Acad. Sci. 3:168, 1946. Bing, R.J., Vandam, L.D. and Gray, F.D., Jr.: Physiological studies in congenital heart disease. I. Procedures. Bull. Johns Hopkins Hosp. 80:107, 1947. Bing, R.J., Vandain, L.D. and Gray, F.D., Jr.: Physiological studies in congenital heart disease. II. Results of pre-operative studies in patients with tetralogy of Fallot. Bull. Johns Hopkins Hosp. 80:121, 1947. Bing, R.J., Vandam, L.D. and Gray, F.D., Jr.: Physiological studies in congenital heart disease. III. Results obtained in five cases of Eisenmenger's Complex. Bull. Johns Hopkins Hosp. 80:323, 1947. Bradley S. and Bing, R.J.: Renal function in the harbot seal (Phoca vitulina L.) duri asphyscial ischemia and pyrogenic pyperemia. J. Cell. Comp. Physiol. 19:229, 1942.

RICAARD JOHN BING, M.D. - 2- • • Bing, R.J., Vandam, L.D., Gregoire, F., Handelsman, J.C., Goodale, W:T. Fe-kenhoff, J.E.: Catheterization of the coronary sinus and the middle cardiac vein in man. Proc. Soc. Exper. Biol. Med. 66:239, 1947. Vandam, L.D., Bing, R.J. and Gray, F.D., Jr.: Physiological studies in congenital heart disease. IV. Measurements of the circulation of five selected cases. Bull. Johns Hopkins Hosp. 81:192,1947. Gray, F.D., Jr., Bing, R.J. and Vandam, L.D.: Evaluation of method involving carbon dioxide and equilibration for determining cardiac output. Amer. J. Physiol. 151:245, 1947. Bing, R.J., Handelsman, J.C. and Campbell, J.A.: Physiologic diagnostic tests in congenital heart disease. Mod. Concepts Cardiovasc. Dis. 17: 1948. Bing, R.J. and Gibson, S.: Symposium on congenital heart disease. Ped. 2:325, 1948. Eckenhoff, J.E., Hafkenschiel, J.H., Harmel, H.M., Goodale, W.T., Lubin, M., Bing, R.J. and Kety, S.S.: Measurement of coronary blood flow by the nitrous oxide method. Amer. J. Ph.ysiol. 152:356, 1948. Houck, C.R., Bing, R.J., Craig, F.N. and Visscher, F.E.: Renal hyperemia after intravenous infusion of adenylic acid, adenosine or adenosine-triphosphate in dog. Amer. J. Physiol. 153:159, 1948• Handelsman, J.C., Bing, R.J., Campbell, J.A. and Griswold, H.E.: Physiological studies in congenital heart disease. V. The circulation in patients with iso- lated septal defects. Bull. Johns Hopkins Hosp. 82:615, 1948. Bing, R.J., Vandam, L.D., Handelsman, J.C., Campbell, J.A., Spencer, R. and Griswold, H.E.: Physiological studies in congenital heart disease with cyanosis. Bull. Johns Hopkins Hosp. 83:439, 1948• Bing, R.J., Vandam, L.D., Handelsman, J.C., Spencer, J., Campbell, J.A., and Griswold, H.E.: Physiological studies in congenital heart disease. VI. Adapta- tions to anoxia in congenit4 heart disease with cyanosis. Bull. Johns Hopkins Hosp., 83: 423, 1948. ~ Bing, R.J., Goodale, W.T., Eckenhoff, J.E., Handelsman, J.C., Campbell, J.A. Griswold, H.E., Vandam, L.D., Harmel, M., Hafkenschiel, J., Lubin, M. and Kety, S.S.: Catheterization of the coronary veins and measurement of the coro- nary blood flow in rnan. J. Clin. Invest. (Proc.) 27:525, 1948. Taussig, H.B. and Bing, R.J.: Complete transposition of the aorta and a levo- position of the pulmonary artery. Amer. Heart J. 37:551, 1949• Griswold, J., Bing, R.J., Handelsman, J.C., Campbell, J.A. and LeBrun, E.: Physiological studies in congenital heart disease. VII. Pulmonary arterial hyper- tension in -cangenitai iie-a.rt -disease:== =Johns=JIopkil ns==Hos=: ---- R3:?6, = 194, Q-. Campbell, J., Bing, R.J., Handelsman, J.C., Griswold, H. and Hammond. M.: physiological studies in congenital heart disease. VIII. The physiological findings in two patients with complete transposition of the great vessels. Bull. Johns Hopkins Hosp. 84:269, 1949•

Or w RICHARD JOHN BING, M.D. - 3- Bing, R.J., Hammond, M., Handelsman, J.C., Powers, S.R., Spencer, F., Eckenhoff, J.E., Goodale, W.T., Hafkenschiel, J. and Kety, S.S.: The measurement of coronary blood flow, oxygen consumption and efficiency of the left ventricle in man. Amer. Heart J. 38:1, 1949. Bing, R.J.: Physiological methodSin the diagnosis of congenital heart disease. Surg. Gyn. Ob. 88:399, 1949. Goldman, I.R., Blount, S.G., Jr., Freidlich, A.L and Bing, R.J.: Electrocardiographic observations during cardiac catheterization. Bull. Johns Hopkins Hosp. 86:141, 1950. Bing, R.J., Maraist, F., Dammann, J.F., Draper, A., Heimbecker, R., Daley, R., Gerard, R. and Calazel, P.: The effect of strophanthus preparations on coronary blood flodr and cardiac oxy'gen consumption of normal and failing hearts. -Circulation 2:513, 1950. Friedlich, A., Heimbecker, A.O. and Bing, R.J.: Device for continuous recording of concentration of Evans blue dye in whole blood and its application to the determination of cardiac output. J. Appl. Physiol. 3:12, 1950. Friedlich, A., Bing, R.J. and Blount, S.G.: Physiological studies in congenital heart disease. IX. Circulatory dynamics in the anomalies of venous return to the heart includirtg pulmonary arteriovenous fistula. Bull. Johns Hopkins Hosp. 80:20, 1950. Bing, R.J., Heimbecker, W., Falholt, A., Friedlich, A. and Carroll, D.: Method for approximation of residual volume of blood in right ventricle. Amer.-.J. Physiol. 163`, 1950. Spencer, F., P7errill, D.L., Powers, S.R. and Bing, R.J.: Coronary blood flow and cardiac oxygen consumption in unanesthetized dogs. Amer. J. Physiol. 160:149, 1950. Draper, A.J., Bing, R.J., Friedlich, A., Heimbecker, R. and Dammann, J.F.: Physiological studies in pre and post-operative mitral stenosis. Abstract. J. Clin. Invest. 29:809, 1950. Bing, R.J.: Physiology of congenital heart disease. Nelson's Loose Leaf iiedicine, 4 :423 , 1950. Calazel, P., Gerard, R., Daley, R., Draper, A., Foster, J. and Bing, R.J.: Physiological studies in congenital heart disease. XI. A comparison of the right and left auricular, capillary and pulmonary artery pressures in nine patients with auricular septal defect. Bull. Johns Hopkins Hosp. 88:20, 1951. Draper, A., Heimbecker, R., Daley, R., Carroll, D., hfudd, G., Wells, R., Faiholt, W., Andrus, C.E. and Bing, R.J.: Physiological studies in mitral valvular disease. Circulation 3:531, 1951. Bing, R.J.: The behavior of the myocardium in health and disease as studied by coronary sinus catheterization. A review. Lo. Stetoscopic, N. 7, Luglio 1951, Roma. Bing. R_.J._ .and_D~leu,-1?- :---?'he--behatrior of--i:he==my--caLd-i-am-i~ri--hie-a-it-ii- =an:d- disease as - studied by coronary'sinus catheterization. Amer. J. Med. 10:711, 1951. 40

RICHARD JOHN BING, M.D. - 4- Biount, S.G., Jr., Ferencz, C., Friedlich, A., Mudd, J.G., Carroll, D.G. and Bing, ~- R.J.: Physiological studies in congenital heart disease. XII. The circulatory dynamics in patients with tricuspid atresia. Bull. Johns Hopkins Hosp. 89:153, 1951. Heimbecker, R., Carroll, D.G., Falholt, W., Iobdd. G., Ferencz, C. and Bing, R.J.: Determination of residual volume of--blood in the right ventricle of normal and disecsed human hearts in vivo. Fed. Proc. (Abstr.). 10:61, 1951. Ziaraist, F., Daley, R., Draper, A., Heimbecker, F., Dammann, F., Kieffer, R., Talbot, K., Ferencz, C. and Bing, R.J.: Physiological studies in congenital heart disease. X. The physiological f indings in 34 patients with isolated pulmonary valvular stenosis. Bull. 3ohns Hopkins Hosp. 88:1-19, 1951. Bing, R.J.: Recent studies of cardiac failures with relation to action of digitalis. Bull. Johns Hopkins Hosp. 88:281, 1951. Daley, R., Wade, J.D., Maxaist, F. and Bing, R.J.: Pulmonary hypertension in dogs induced by injection of lycopodium spores into the pulmonary artery with special reference to absence of vasomotor reflexes. Amer J. Physiol. 164:380, 1951. Bing, R.J., Heinb•acker, R. and Falholt, W.: An estimation of the residual volume of blood in the right ventricle of normal and diseased hum2a hearts in vitro. Amer. Heart J. 42:483, 1951. Bing, R.J. and Carroll, D.: Physiological tests in cardiovascular pulmonary disease. Lancet. 71:444, 1951. Andrus, E.C., Blalock, A. and Bing, R.J.: The surgical treatmenit of mitral stenosis and its physiological consequence. Trans. A. Amer. Phys. 64:335, 1951; also, Bull. Johns Hopkins Hosp. 90:175, 1952. Bing, R.J.: Coronary circulation in health and disease as studied by coronary sinus catheterization, Bull. N.Y. Acad. Med. 27:407, 1951. Bing, R.J. aL~.d Taeschler, M,: Cardiac failure and cardiac muscle. Cardiologia 21:2 83 , 1952. Bing, R.J.: The regulation of the dynamic and metabolic function of the human heart. Acta. Med. Scandinav. Supp. 266:223, 1952. Bing, R.J., Lombardo, T.A., Bargeron, L.M,, Taeschler, M, and Tuluy, S.: Congenital heart disease, a clinical and physiologic correlatio::. Anna Int. Med. 37 : 664 , 1952. Bing, R.J.: Congenital heart disease, an introduction and classification. Amer. J. ilbd. 12:77, 1952. Bing, R.J.: Catheterization of the heart. Adv. Int. %'Ied. 5:59, 1952. Bing, R.J.: The role of coronary circulation in shock. Ann. N.Y. Acad. Sci. 55-•:367, 1952. Taeschler, M. and Bing, R.J.: Some properties of actomyosin strips of heart muscle, Fed. Proc. 11:i5S, 1952 (P_bstract).

RICHARD JOHN BING, M.D. - 5- w S Taeschler, M., Lombardo, G., Siegel, A. and Bing, R.J.: Metabolic studies of the human heart in vivo. Am. J. Physiol. 171:1952. Bing, R,J.: Diseases of the cardiovascular system. Ann. Rev. 1~d. 4:55, 1953. Bing, R.J. and Siegel, A.: P•ttabolism of the human heart in vivo. Quarterly J. Phi Beta Pi 1:62, 1953. Bing, R.J.: i6etabolism of the human heart in vivo. Friesner Lecture.. Bull. i•4t. Sinai Hosp. 20:100, 1953. Taeschler, i,. and Bin;, R.J.: Some properties of contractile proteins of the heart as studied on the extracted heart muscle preparation. Circulation Res. 1:129, 1953. Lcz-ibardo, T.A., Rose, L., Taeschler, i4. , Tuluy, S. and Bing, R.J. : The effect of exercise on coronary blood flow, myocardial oxygen consumption and cardiac efficiency in man. Circulation 7:71, 1953. Bing, R.J., Siegel, A., Vitale, A., Balboni, F. and Sparks, E.: Metabolism of the human heart in vivo. J. Clin. Invest. 32:556, 1953. Cournand, A., Bing, R.J., Dexter, L., Dotter, C., Katz, L.N., Warren, J.V. and Wood, E.: Report of the committee on cardiac catheterizations and angiocardiography. Circulation 7:769, 1953. Bing, R.J.: Collateral circulation of the heart. Symposium on circulation and hemeostasis. 2~irzrj Medical Service Graduate School, Oct., 1953. Damaann, F., Bethrong, M. and Bing, R.J.: Reverse ductus. A presentation of the syndrome of potency of the ductus arteriosus with pulmonary hypertension and shfinting of blood flow from pulmonary artery to aorta. Bull. Johns Hopkins Hosp. 92:128, 1953. Edw4rds, W.S., Reber, W.E., Siegel, A. and Bing, R.J.: Coronary blood flow and myocardial o-.,ygen consumption in hemorrhagic shock. Surg. Forum 4:505, 1953. Bing, R.J., Siegel, A., Vitale, A., Balboni, F., Sparks, E., Taeschler, M., P.lapper, M. and Edwards, W.S.: Metabolism of the human heart. I. Carbohydrate metabolism. Amer. J. Med. 15:284, 1953. Edwards, W., Tuluy, S., Reber, W.E., Siegel, A. and Bing, R.J.: Coronary blood flow and myocardial metabolism in hypothermia. Ann. Surg. 139:275, 1954. Bing, R.J.: Sid ificance of the newer knowledge of contractile proteins for cardiology. Proc. Second World Congress of Cardiology, 1954; Am. Heart Association. Bing, R.J.: Congenital cardiac deformities: I. Introduction and classification. Medizinis=:ie 22:769, 1954; Nedizinische 23:805, 1954; Medizinische 24:837, 1954. Bing, R.J., Reber, W.E., Sparks, E., Balboni, F., Vitale, A. and Hanlon, tiI.: Congenital pulmonary stenosis. J.A.M.A. 154:127, 1954. Bing, R.J., Siegel, A., Ungar, I. and Gilbert, M.: Metabolism of the human heart. II. Studies on fat, ketone, and amino acid metabolism. Amer. J. Med. 16:504, 1954.

RICHARD JOHN BING, M.D. - 6- • Edwards, W.S., Siegel, A. and Bing, R.J.: Studies on myocardial metabolism. III. Coronary blood flow, myocardial oxygen consumption and carbohydrate metabolism in experimental hemorrhagic shock. J. Clin. Invest. 33:1546, 1954. Stutz, H., Feigelson, E., Emerson, J. and Bing, R.J.: The effect of digitalis (Cedilanid) on the mechanical and electrical activity of extracted and nonextracted hearte muscle preparation. Circulation Res. 2:555, 1954. Ungar, I., Gilbert, H., Siegel, A., Blain, J.i4. and Bing, R.J.: Studies on myocardial metabolism. IV. Myocardial metabolism in diabetes. Amer. J. Med. 18:385, 1955. Bing, R.J.- 2,1etabolism of the heart. Acta Cardiologica 10:1, 1955. Bing, R.J.: Cardiac catheterization. Henry Ford Hospital International Symposium on Cardiovascular Surgery, harch, 1955. Bing, R.J.: Metabolism of the human heart. Clinical Progress. Circulation 12:535, 1955. Edwards, W.S., Simmons, E., Lombardo, C., Bennett, A. and Bing, R.J.: Coronary blooo flow in hypothermia. A.M.A. Arch. Surg. 71:853, 1955. Bing, R.J.: Homeostatic mechanisms in congenital heart disease. Presented at St. Francis Sanatorium, October, 1955. Bing, R.J.: Metabolism of the heart. Hatvey Lecture Series L. Academic Press, p. 27., 1954-1955. Bing, R.J.: Der N'ryocardstoffwechsel. Klin. Wochenschrift. 34:1, 1956. Blain, J.M., Eddleman, E.E., Siegel, A. and Bing, R.J.: Studies on myocardial metabolism. V. The effects of lanatoside-C on the metabolism of the human heart. J. Clin. Invest. 35:314, 1956. Schafer, H., Blain, J.M., Ceballos, R. and Bing, R.J.: Essential pulmonary hypertens ion. Ann. Int. W. 44 :405 , 1956. . Gonlubol, F., Siegel, A. and Bing, R.J.: The effect of a cardiac glycoside (Cedilanid) on the sodium and potassium balance of the human heart. Circulation Res. 4:298, 1956. Siegel, A. and Bing, R.J.: Plasma enzyme activity in myocardial infarction in dog and man. Proc. Soc. Exper. Biol. W. 91:604, 1956. Bing, R.J.: Disturbances in myocardial metabolism. Adv. in Cardiol. 1:52, 1956. Blain, J.I1., Schafer, H., Siegel, A. and Bing, R.J.: Studies in myocardial metabolism. VI. Nyocardial metabolism in congestive failure. Amer. J. Nled. 20:820, 1956. 41111 Bing, R.J.: Hemeostatic aspects of congenital heart disease. Bull. St. Francis Hosp. 13:1, 1956.

RICHARD JOHN BING, M.D. - 7- • w S Dettli, L. and Bing, R.J.: Contractility and extractability of heart actouyosin after death. Circulation Res. 4:519, 1956. Bing, R.J.: The contribution of physiology to cardiovascular surgery. Georg Thieme Verlag Stuttgart, 1956. Pedersen, A., Siegel, A. and Bing, R.J.: Cardiac metabolism in experimental ventricular fibrillation. Amer. Heart J. 52:695, 1956. Bing, R.J., Castellanos, A., Gradel, E., Lupton, C. and Siegel, A.: Experimental coronary infarction: Circulatory, biochemical and pathologic changes. Amer. J. Med. Sci. 232:1956. Dettli, L. and Bing, R.J.: Contractile properties of actomyosin threads and bands prepared from dogs' hearts. Amer. J. Physiol. 187:145, 1956. Bing, R.J., Castellanos, A., Gradel, E., Siegel, A. and Lupton, C.: Enzymatic metabolic, circulatory and pathologic studies in myocardial infarction. Trans. of Assoc. Amer. Physicians 69: 1956. Bing, R.J.: Heart metabolism. Scientific American 196:50, 1957. Bing, R.J.: Myocardial metabolism in diabetes. Diabetes (The J. of Amer. Diabetes Assoc.) 6:95, 1957. Bargeron, L.M., Ehmke, D., Gonlubol, F., Castellanos, A., Siegel, A. and Bing, R.J.: The effect of cigarette smoking on coronary blood flow and myocardial metabolism. Circulation 25:251, 1957. Bing, R.J., Castellanos, A. and Siegel, A.: The diagnostic value of plasma activity of malic acid dehydrogenase and phosphohexose isomerase in patients with myocardial infarction and liver disease. J.A.M.A. 164:647, 1957. Bing, R.J.: Cardiology divided (Editorial) Circulation 16:521, 1957. Beuren, A., Sparks, C.H. and Bing, R.J.: Metabolic studies on the arrested and fibrillating perfused heart. Amer. J. Cardiol. 1:103, 1958. Cabrera, G., Beuren, A. and Bing, R.J.: Determinations of DPN (TPN) thiamine, amino acids and amino sugars in blood of animals with experimental myocardial infarction. Circulation Res. 6:15, 1958. Kako, K. and Bing, R.J.: Contractility of actomyosin bands prepared from normal and failing human hearts. J. Clin. Invest. 37:465, 195$• Mack, R., Nolting, D., Kirsch, M., Luthy, E., Choudhury, J.D. and Bing, R.J.: Determination of coronary blood flow with Rubidium-86. Fed. Proc. 17:1, 1958. Bing, R.J.: Metabolism of the heart (Le Metabolismeedu Coeur). La Presse Medicale 66:1015, 1958. Danforth, W. and Bing, R.J.: The heart in anoxia and ischemia. Brit. J. Anesth. 30: 456, 1958.

RICHARD JOHN BING, M.D. - 8- w w Bing, R.J.: Cardiac metabolism in myocardial failure. Symposium delivered at Third World Congress of Cardiology, Brussels, Belgium. Sept. 1958. Reynolds, J.R.M., Kirsch, M. and Bing, R.J.: Functional capillary beds in the beating KCI arrested and KCI arrested-perfused myocardium of the dog. Circulation Res. 6 : 600 , 1958. Bing, R.J., Choudhury, J.D., Michal, G., and Kako, K.: Nryocardial metabolism. Ann. Int. Med. 49:1201, 1958. Bing, R.J., Kardesch, M., Hogencamp, C.E. and Michal, G.: The survival of excitability, energy production and energy utilization of the heart. Trans. Assoc. Amer. Physiol. 71:152, 1958. Kardesch, M., Hogencamp, C.E. and Bing, R.J.: The survival of excitability, energy production and energy utilization of the heart. Circulation 18:935, 1958. 57:214, 1959. Hogencamp, C.E., Kardesch, M., Danforth, W. and Bing, R.J.: Transmembrane electrical potentials in ventricular tachycardia and fibrillation. Amer. Heart J. Michal, G. and Bing, R.J.: Myocardial efficiency. N.Y. Acad. Sci. 72:555, 1959. Bing, R.J.: Cardiac metabolism in myocardial failure. Adv. in Cardio. 2:148, 1959. Bing, R.J.: The development of modern concepts of the coronary circulation. Texas State J. i*-d. 55:665, 1959. Naegle, S. Danforth, W., Bing, R.J. and Helmreich, E.: Glycolytic reaction in the heart. Hoppe-Seyler's Zeitschrift fur physiologische Chemie. 316:113, 1959. Bing, R.J.: Importance of chemical transmission in cardiology and neuropharmacology. Arch. Int. Med. 104:658, 1959. Bing, R.J. and Beuren, A.J.: Der stoffwechsel des herzens. Ergebn. inn. Med. Kinderheilk. 11:104, 1959. Danforth, W.H., Hogencamp, C.E., Ballard, F.B. and Bing, R.J.: The myocardial metabolism of fructose. Amer. J. Med. 238:477, 1959. Bing, R.J.: Congenital heart disease. Ann. Vol. Physiol. & Exp. Med. Sc. India 2:7, 1958-19159. Mack, R.E., Bing, R.J., Nolting, D.D. and Hogencamp, C.E.: Myocardial extraction of Rub id ium-86 in th e rabb it . Amer. J. Ph,ysiol. 19°j:1175, 1959. Bing, R.J.: The heart in congestive failure. Texas State J. Iied. 55:931, 1959. Danforth, W. and Bing, R.J.: Metabolic changes in heart muscle during anoxia. Amer. J. Pb,ysiol. 197 :1.147, 1959. Bing, R.J.: Physiology of the myocardium. J.A.M.A. 172:438, 1960. Danforth, W.H., Ballard, F.B., Kako, K., Choudhury, J.D. and Bing, R.J.: Metabolism of the heart in failure. Circulation 21:112, 1960.

RICHARD JOHN BING, M.D. - 9 • Ballard, F., Danforth, W., and Bing, R.J.: Myocardial metabolism of fatty acids. J. Clin. Invest. 39:717, 1960. Bing, R.J., Hellems, H.K., Regan, T.J.: Measurement of coronary blood flow in man. Editorial. Circulation 22:1, 1960. Bing, R.J.: Myocardial metabolism. J. of Med. 15:163, 1960. Danforth, W.H., Haegle, S. and Bing, R.J.: Effect of ischemia and reoxygenation on glycolytic reactions and adenosinetriphosphate in heart muscle. Circulation Res. 8:965, 1960. Kako, K., Choudhury, J.D. and Bing, R.J.: Possible mechanism of the decline in mechanical efficiency of the isolated heart. J. Pharm. & Exp. Therap. 130 : 46, lg6o. Bing, R.J.: Fundamental considerations in practical cardiology. J. Mich. State Med. Soc. 59:1700, 1960. Bing, R.J.: Cardiac muscle metabolism. In: Modern Trends in Cardiology. Butterworth & Co., Ltd. London, 1960. Kako, K., Chrysohou, A. and Bing, R.J.: Storage of catecholamines in the heart. Amer. J. Cardiol. 6:1109, 1960. Bing, R.J.: Enzyme regulations in clinical medicine. Proc. Sixth International o Congress Int..Med. Basel, 1960. Bing, R.J.: The relationship between biochemical activity and mechanical function of the heart. Estratto da, Atti del 1' Symposium sull'estere di Cori e glucidi _fosforilati. Milan, September 1960. Regan, T.J., Frank, M.J., McGinty, J.F., Zobl, E., Hellems, H.K. and Bing, R.J.: Myocardial response to cigarette smoking in normal subjects and patients with coronary disease. Circulation 23:365, 1961. Kako, K., Chrysohou, A. and Bing, R.J.: Factors affecting myocardial storage and release of catecholamines. Circulation Res. 9:295, 1961. Bing, R.J.: Metabolic activity of the intact heart. Amer. J. Med. 30:679, 1961. Bing, R.J., Chiba, C., and Kako, K.: New frontiers in cardiology. Japanese Heart Journal. 2:277, 1961. Klarwein, M., Kako, K., Chrysohou, A. and Bing, R.J.: The effect of atrial and ventricular fibrillation and of ventricular tachycardia on carbohydrate metabolism of the heart. Circulation Res. 9:819, 1961. Bing, R.J.and Engel: Conference on Shock. Discussion of Papers by Dr. Guyton and Dr. Green. Fed. Proc. 20:part 3, #2. F Bing, R.J.: Rehabilitation in heart disease. Arch..Environ. Health. 3:304, 1961.

RICHARD JOHN BING, M.D. - 10 - Rothlin, M. and Bing, R.J.: Extraction and release of individual free fatty acids by the heart and fat depots. J. Clin. Invest. 40:1380, 1961. Bing, R.J. and Kako, K.: Contractile proteins of heart muscle in man. Circulation 21+:483, 1961. Morse, W.H. and Bing, R.J.: Congestive heart failure: Its physiopathology and treatment with special reference to intractable heart failure. Postgrad. Med. 30:293, 1961. Bing, R.J.: Uber den stof#;wechsel des intakten Herzens. Verhandlungen der Deutschen Gessellschaft fur Kreislaufforschung 27 Tagung. Seite 145-166, 1961. Sundermeyer, J.F., Gudbjarnason, S., Wendt, V.E., den Bakker, P.B. and Bing, R.J.: Myocardial metabolism in progressive muscular dystrophy. Circulation 24:1348, 1961. Bing, R.J., Chiba, C., Chrysohou, A., Gudbjarnason, S., Wolf, P.L.: Metabolic, histologic and histochemical aspects of the homografted heart. Trans. Asso. Amer. Physiol. 74:318, 1961. Bing, R.J.: Cardiac glycosides and heart metabolism. Biochem. Pharm. Pergamon Press.8, 1961. Bing, R.J.: Myocardial metabolism in hemorrhagic shock. Fed. Am. Soc. Exp. ~ Biol. 1961. Bing, R.J.: The anoxic heart. Henry Ford Hospital Sympositinn, November 1961. Bing, R.J., Chiba, C., Chrysohou, A., Wolf, P.L. and Gudbjarnason, S.: Transplantation of the heart. Editorial. Circulation 25:.2f3, 1962. Wendt, V.E., Sundermeyer, J.F., den Bakker, P.B. and Bing, R.J.: The relation- ship between coronary blood flow, myocardial oxygen consumption and cardiac work as influenced by Persantin and other pharmacologic agents. Amer. J. Cardiol. 9: 449, 1962. Bing, R.J.: The effect of cigarette smoking on coronary blood flow and cardiac work in normal subjects and patients with coronary disease. Reprinted from James and Rosenthal, et al. Tobacco and Health, Springfield, Illinois, Charles C. Thomas, Publisher, 1962. Bing, R.J.: Estimation of cardiac function and coronary blood flow. Modern Medicine 87:91, 1962. Wegmann, A., Chiba, C., Chrysohou, A. and Bing, R.J.: Catecholamine in homologous heart grafts. Proc. Soc. Exper. Biol. & Med. 109:543, 1962. Chiba, C., Chrysohou, A.,Gudbjarnason, S., Wolf, P.L. Ramos, H., Pearson, B. and Bing, R.J.: Studies on the transplanted heart. Its metabolism and histology. J. Exp. Med. 115:853, 1962.

. RICHARD JOHN BING, M.D. - 11 - S • Gudbjarnason, S. and Bing, R.J.: The redox-potential of the lactate-pyruvate system in blood as an indicator of the functional state of cellular oxidation. Biochemica et Biophysica Acta. 60:158, 1962. den Bakker, P.B., Sundermeyer, J.F., Wendt, V.E., Salhaney, M., Gudbjarnason, S. and Bing, R.J.: Myocardial metabolism in a patient with Hashimoto's thyroid- itis with hypothyr®idism:A case report with metabolic studies. Amer. J. Med. 32:822, 1962. Bing, R.J. and Ramos, H.: The role of the heart in shock. J.A.M.A. 181:871, 1962. Wendt, V.E., Sundermeyer, J., den Bakker, P.B. and Bing, R.J.: Special diagnostic procedures in cardiac surgery. In: Surgerv of the Chest, by John Gibbon, III, W.B. Saunders Co. 1962. Gadd, C.W. and Bing, R.J.: Remotely operated cardiac catheter. J. Lab & Clin. Med. 60:167, 1962. Stock, T.B., Wendt, V.E., Hayden, R.O., Bruce, T.A. and Bing, R.J.: New concepts of angina pectoris. Med. Clin. N.Amer. 46:1497, 1962. Wendt, V.E., Stock, T.B., Hayden, R.O., Bruce, T.A., Gudbjarnason, S. and Bing, R.J.: The hemodynamics and cardiac metabolism in cardiomyopathies. Med. Clin. N. Amer. 46:1445, 1962. Wegmann, A., Kako, K. and Bing, R.J.: Catecholamine content of various organs in experimental hypertension. Amer. J. Physiol. 203:607, 1962. Gudbjarnason, S., Hayden, R.O., Wendt, V.E., Stock, T.B. and Bing, R.J.: Oxidation= reduction in heart muscle: Theoretical and clinical considerations. Circulation 26:937, 1962. Bing, R.J.: Normal myocardial metabolism. In: Coronarv Heart Disease, Ed. Wm. Likoff and J.H. Moyer, 1963. Nebel, M. and Bing, R.J.: Contractile proteins of the normal and failing human heart. Arch. Int. Med. 111:190, 1963. Bing, R.J.: Withering and the quarterly journal of negative results. Arch. Int. Med. 111:143, 1963. Ramos, H.R., Chiba, C., Schollmeyer, P., Wolf, P.L., Pearson, B. and Bing, R.J.: The presence of humoral factors in homograft rejection of the transplanted heart. Transplantation 1:284, 1963. Chiba, C., Yamanaka, J., Zaleski, E.J., Wolf, P.L. and Bing, R.J.: Studies on the transplanted heart: The role of gamma globulins in transplantation immunity. Proc. Soc. Exp. Biol. Med. 114:637, 1963. Luthy, E., and Bing, R.J.: The effect of a heart extract on the coronary blood flow and myocardial oxygen consumption in dogs. Cardiologia 43:391-398. 1963.

RICHARD JOHN BING, M.D. - 12 - • Schollmeyer, P., Chiba, C., Wolf, P.L. and Bing, R.J.: Untersuchungen uber die sensibiliesierung transplanatate und.die gegenwart humoraler fektoren bei ihrer rejektion am modell...Verh. Deutsch. Ges. Kreislauf. Frschg. 29:192, 1963. Gudbjarnason, S., Telerman, M. and Bing, R.J.: Protein metabolism in cardiac hypertrophy and heart failure. Amer. J. Physiol. 206:294, 1964. Ribeilima, J., Wendt, V.E., Ramos, H.R., Gudbjarnason, S., Bruce, T.A. and Bing, R.J.• The effects of norepinephrine on the hemodynamics and myocardial metabolism.of normal human subjects. Amer. Heart J. 67:672, 1964. Bing, R.J., Bennish, A., Bluemchen, G., Cohen, A., Gallagher, J.P. and Zaleski, E.J.: The determination of coronary flow equivalent with coincidence counting technique. Circulation 29:833, 1964• Bing, R.J., Gudbjarnason, S., and Bluerachen, G.: Proteinsynthese Ud turnover rates im Herzmuskel. Herzin. Hamodynamik 'und Stoffwechsel 4:175, 1964. Wu, C., Doty, G., Wendt, V.E. and Bing, R.J.: Pathophysiology of congestive heart failure. J. of Med. Sci. 1:61-75, 14. Gudbjarnason, S., DeSchryver, C., Chiba, C., Yamanaka, J. and Bing, R.J.: Protein and nucleic acid synthesis during the reparative processes following myocardial infarction. Circulation Res. 15:320, 1964. Bing, R.J., Wu, C. and Gudbjarnason, S.: Mechanism of heart failure. Circulation Res. 14:11, 1964. Bing, R.J., Cohen, A. and Bluemchen, G.: Tobacco alkaloids and circulation. Proc. 4th International Symposium: Tobacco Alkaloids and Related Compounds. Edited by U.S. Von Euler, Pergamon Press, Stockholm, February, 1964, page 241. Gudbjarnason, S., DeSchryver, C., Hunn, G. and Bing, R.J.: Changes in myo- cardial enzyme pattern in human heart disease. J. Lab. Clin. Med. 64:796, 1964. Ribeilima, J. and Bing, R.J.: Selective embolization of the coronary arteries. Proc. Soc. Exp. Biol. Med. 117:367, 1964. Bassenge, E., Wendt, V.E., Schollmeyer, P., Bluemchen, G., Gudbjarnason, S. and Bing, R.J.: The effect of ketone bodies on cardiac metabolism. Amer. J. Physiol. 208:162, 1965. Bing, R.J.• Action of digitalis. 11th Hahnemann Symposium. In: Cardiovascul.ar Drug era.v. Published by Grune and Stratton, New York, pg. 434, 1965. Wendt, V.E. Balcon, R., Ribeilima, J. and Bing, R.J.: Circulatory changes following experimental myocardial infarction. 12th Hahnemann Symposium. In: Shock and otension - Patho enesis and Treatment. Published by Grune and Stratton, New York, pg. 492, 1965. 0

RICHARD JOHN BING, M.D. - 13 - S • Gudbjarnason, S., Telerman, M., Chiba, C., Wolf, P.L. and Bing, R.J.: ?Ayocardial proteins synthesis in cardiac hypertrophy. L. Lab. Clin. Med. 63:245, 1964. Wendt, V.E., Wu, C., Balcon, R. and Bing, R.J.: Metabolic factors in the control of cardiac output. 12th Hahnemann Symposium. In: Shock and Hvmo- ,tension - Pathogenesis and reatment. Published by Grune and Stratton, New York, pg. 32, 1965. Wendt, V.E., Wu.,C., Balcon, R., Doty, G. and Bing, R.J.: The hemodynamic and metabolic effects of chronic alcoholism in man. Amer. J. Cardiol. 15: 175, 1965. Bruce, T.A. and Bing, R.J.: Clinical management of myocardial infarction. J.A.M.A. 19l:124, 1965. • Bing, R.J.: Cardiac metabolism. Physiol. Rev. 45:171, 1965. Bing, R.J.: Refractory heart failure. Hospital Medicine 2:2, 1965. Bing, R.J. and Fenton, J.C.: Cardiac Metabolism. Ann. Rev. Med. 16:1, 1965. Chiba, C., Rosenblatt, M., Yamanaka, J., Wolf, P.L., Bassenge, E. and Bing, R.J.: Inmunologically produced lymphopenia. Arch. Int. Med. 115:558, 1965. DeSchryver, C., Gudbjarnason, S. and Bing, R.J.: Myosin synthesis in chronic heart failure. Proc. Soc. Exp. Biol. Med 119:961, 1965. Cohen, A., Gallagher, J.P., Luebs, E.D., Varga, Z., Yamanaka, J. Zaleski, E.J., Bluemchen, G. and Bing, R.J.: The quantitative determination of coronary blood flow with a positron emitter (Rubidizmm-84). Circulation 32:636, 1965. Cohen, A., Zaleski, E.J., Luebs, E.D. and Bing, R.J.:- The use of a positron emitter in the determination of coronary blood flow in man. J. Nuclear Med. 6:651, 1965. Wendt, V.E., Wu, C., Ajluni, R., Bruce, T.A., Prasad, A. and Bing, R.J.: The acute and chronic effects of alcoholism on the myocardium. Ann. int. Med. 62:1068, 1965. Bing, R.J.: The recognition of coronary artery disease. 37th Symposiun, American Heart Association. Advances in Detection of C oronary Artery Disease. Circulation 32:620, 1965. Gudbjarnason, S., Ribeilima, J. and Bing, R.J.: Metabolism of the heart in failure. Acta. Cardiologica 20:371, 1965. Wolf, P.L. and Bing, R.J.: The smallest tumor which causes sudden death. J.A.M.A. 194:674, 1965. Cohen, A., Luebs, E.D., Zaleski, E.J. and Bing, R.J.: A new diagnostic test for coronary artery disease using a coincidence counting system. Minnesota Med. 1+9:17, 1966.

RICHARD JOHN BING, M.D. - 14 - • S Luebs, E.D., Cohen, A., Zaleski, E.J. and Bing, R.J.: The effect of nitro- glycerin, intensain, isoptin and papavarine on coronary blood flow in man, as measured by the coincidence counting technique and Rubidium-84. Amer. J. Cardiol. 17:535, 1966. Zaleski, E.J., Cohen, A. and Bing, R.J.: An new test in the diagnosis of arteriosclerotic heart disease. Oakwood Journal 1:15, 1966. Bruce, T.A. and Bing, R.J.: Catheterization of the coronary sinus. In: =ntravascUar Catheterization, 2nd edition, edited by Henry A. Zimmerman, Pub- lished by Charles C. Thomas, Springfield, Ill., page 888, 1966. Zuehlke, V., du Mesnil, V., Gudbjarnason, S. and Bing, R.J.: Inhibition of protein synthesis in cardiac hypertrophy and its relation to myocardial failure. Circulation Res. 18:558, 1966. Bing, R.J.,Puri, P., Robin, E., Martinez, M., Ogawa, K.: The comparison of experimental and clinical evaluation of anti-anginal agents. In: Proceedings of the III Pharmacolo~ical Meg jr , Vol. 3, pg• 29-43, Pergamon Press. London, 1965. Rosenblatt, M., Chiba, C., Motoyoshi, T., Morris, A., Zuehlke, V., Wolf, P. and Bing, R.J.: The production of a state of active immunity to isologous and autologous seriun.proteins. Amer. J. Clin. Path. 46:362, 1966. Balcon, R. and Bing, R.J.: Ischemic,heart disease. In: Current Diagnosi.s. Howard F. Conn, M.D., Robert J. Clohecy, M.D. and Rex B. Conn, Jr. Editors, W.B.Saunders Co. Philadelphia and London, pg. 201, 1966. Gudbjarnason, S., Fenton, J.C. and Bing, R.J.: Stimulation of reparative pro- cesses following myocardial infarction. Arch. Int. Med. 118:33, 1966. Cohen, A., Luebs, E.D., Zaleski, E.J. and Bing, R.J.: Test for coronary artery disease. Modern Medicine 34:113, 1966 (Abstract). Wendt, V.E., Ajluni, R., Bruce, T.A., Prasad, A.S. and Bing, R.J.: The acute effects of alcohol on the human myocardiwn. Amer. J. Cardiol. 17:804, 1966. Fenton, J.C., Gudbjarnason, S. and Bing, R.J.: Metabolism of the heart in failure. American Heart Association. Monograph No. 1, 2nd edition, page 32, 1966. Fenton, J.C., Gudbjarnason, S. and Bing, R.J.: Hypoxia in the genesis of cardiac arrhythmias. l4th Hahnemann Symposiiun . In: Mechanisms and Ther of Cardiac_Arrh_v_thmias. Leonard S. Dreifus, M.D. and William Likoff, M.D., editors, page, 58, 1966. Rakusan, K. and du Mesnil de Rochemont, W.: Introduced by Richard J. Bing. Capillaries in heart and skeletal muscle of dog and rabbit. Proc. Soc. Exp. Biol. Med. 124:838, 1967. Chiba, C., Kondo, M., Rosenblatt, M., Wolf, P. and Bing,R.J.: Selective irradiation of canine lymph nodes by intralymphatic injection of P-32. Transplantation 5:232, 1967.

RICHARD JOHN BING, M.D. - 15 - S • Cohen, A., Mamen, J., Ragheb, M., Baleiron, H., Zaleski, E.J. and Bing, R.J.: Effects of aipha-methyldopa on the myocardial blood flow, utilizing the coincidence counting method. J. Clin. Pharma. 7:77, 1967. Bing, R.J.: Scanning of the heart. New York State J. Medicine 67:1406, 1967. Cohen, A. Zaleski, E.J., Baleiron, H. Stock, T.B., Chiba, C. and Bing, R.J.: Measurement of coronary blood flow using Rubidium-84 and coincidence counting method. A critical analysis. Amer. J. Cardiol. 19:556, 1967. Robin, E., Cowan, C., Puri, P., Ganguly, S., deBoyrie, E., Martinez, M., Stock, T.B., and Bing, R.J.: A comparative study of nitroglycerin and prop- ranolol. Circulation 36:175, 1967. Ogawa, K., Gudbjarnason, S. and Bing, R.J.: Nitroglycerin (glyceryl trinitrate as a monoamine oxidase inhibitor. J. Pharm. Exper. Therap. 155:449, 1967. Cohen A., Zaleski, E.J. and Bing, R.J.: Measurement of coronary blood flow with radioisotopes. Medical Times 95:573, 1967. Madeira, R., du Mesnil de Rochement, W., Gadd, C., Stock, T.B., and Bing, R.J.: Measurement of the shortening of cardiac fibers in man. Amer. J. Cardiol. 19:686, 1967. Gudbjarnason, S., Cowan, C. and Bing, R.J.: Increase in hexose-monophosphate shunt activity during tissue repair. Life Sciences 6:1093, 1967. Rakusan, K., du Mesnil de Rochement, W., Braasch, W.,-Tschopp, H. and Bing, R.J.: Capacity of the terminal vascular bed during normal growth, in cardio- megaly and in cardiac atrophy. Circulation Res. 21:209, 1967. Bing, R.J.: Herzstoffwechsel. Published in: Das Medizinische Prisma, 1967, C.H. Boehringer Sohn, Ingelheim am Rhein, page 1-28, 1967. Zaleski, E.J., Cohen, A. and Bing, R.J.: Coronary blood flow measurement using the coincidence method and Rubidium-84. In: Animal and Clinical Piarmac Technigues in Druf Evaluation, Vol. 2. pp. 471- 77, 1 7, edited by Peter Siegler, M D. and John Moyer, M.D., Year Book Medical Publishers, Inc. Bing, R.J. and Gudbjarnason, S.: Biochemical reactions of the heart muscle to myocardial ischemia. In: Coronarv Circul-, a.tion and Energetics of the Myocardium. pp. 237-248, 1967, edited by G. Marchetti and B. Taccardi, S. Karger of Basel/N.Y. Bing, R.J.: Why change the medical curriculum? J. Med. Education 42:883-885, 1967. Puri, P., Ganguly, S. and Bing, R.J.: Myocardial contractility of the intact heart. Cardiologia (Editorial) 51:257, 1967. Gudbjarnason, S., Cowan, C., Braasch, W. and Bing, R.J.: Changes in enzyme pat- tern in heart muscle during tissue repair. Cardiologia 51:148-159, 1967.

RICHARD JOHN BING, M.D. - 16 - I S Bing, R.J. and Gudbjarnason, S.: Heart metabolism. In: Encyclopedia of Biochemistry. Reinhold Publishing Co., 1967. Rakusan, K., du Mesnil de Rochemont, W., Hanlon, J., Braasch, W., Tschopp, H. and Bing, R.J.: Effect of nicotine and vasopressin on capillary blood flow and'capacity of the terminal vascular bed. Med. Ph.armcol. Exp. 17:119-128, 1967. Puri, P. and Bing, R.J.: Evaluation of myocardial force-velocity relation in close-chest dogs. Amer. J. Physiol. 214:1273-1279, 1968. Puri, P. and Bing, R.J.: Effect of drugs on myocardial contractility and afterload in the intact dog and experimental myocardial infarction. Amer. J. Cardiol. 21:886-893, 1968. Bing, R.J., Boettcher, D. and Cowan, C.: What is cardiac Failure? Amer. J. Cardiol. 22:2-6, 1968. Braasch, W., Gudbjarnason, S., Puri, P., Ravens, K. and Bing, R.J.:Early changes in energy metabolism in the myocardium following acute coronary artery occlusion in anesthetized dogs. Circulation Res. 23:429-1+38, 1968. Corsini, G., Puri, P., Duran, P. and Bing, R.J.: Effect of nicotine on capillary flow and terminal vascular capacity of the heart in normal dogs and in animals with restricted coronary circulation. J. Pharma. Exp. Therap. 163:353-361, 1968. Marciniak, M., Gudbjarnason, S., Bruce, T. and Bing, R.J.: The effect of chronic alcohol administration on enzyme profile and glyceride content of heart muscle, brain and liver. Proc. Soc. Exp. Biol. & Med. 128:1021-1025, 1968. Robin, E. and Bing, R.J.: Action of alcohol, nicotine and cigarette smoking on the heart. Medicine and Hygiene 834:857-865, 1968. Bing, R.J., Cowan, C., Boettcher, D., Corsini, G. and Daniels, C.: A new method of measuring coronary blood flow in man. J.A.M.A. 205:277-280, 1968. Puri, P., Alamy, D. and Bing, R.J.: Effect of nicotine on contractility of the intact heart. J. Clin. Pharmacol. 8:295-301, 1968. Bing, R.J.: The correlation between blood supply and function of the heart. J. Cardiovasc. Surg. (Memorial'article for Dr. Blalock) 9:392, 1968. Bing, R.J., Corsini, G., Gudbjarnason, S., Puri, P. and Robin, E.: The correlation between blood supply and function of the heart. Presented at Symposium - Correlation of blood supply with metabolism and function, Tbilisi, Georgia, U.S.S.R. J. Cardiovasc. Surg. 9:392, 1968. Gudbjarnason, S., Braasch, W., Cowan, C. and Bing, R.J.: Metabolism of in- farcted heart muscle during tissue repair. Amer. J. Cardiol. 22:360, 1968.

RICHARD JOHN BING, M.D. - 17 - I Rakusan, K., du Mesnil de Rochemont, W., Hanlon, J., Braasch, W., Tschopp, H. and Bing, R.J.: Effect of nicotine and vasopressin on the terminal vascular bed of the heart. Clin. Pharma. Therap. 9:24, 1968. Corsini, G., Boettcher, D., Goldschager N., and Bing, R.J.: Measure- ment of total and nutritional coronary blood flow using coincidence counting. In: Advances in Coronary Heart Disease., published by J.B. Lipincott Co. Philadelphia, Dr. Henry Russek, ed. 1968. Bing,, R.J., Tschopp, H. Rakusan, K. and Gudbjarnason, S.: Physiologic studies on revascularization of the dog heart. J. Thoracic Cardiovas. Surg. 55:466, 1968. Bing, R.J. and Douglass, G.H.: Myocardial infarction - Basic clinical and therapeutic considerations. Michigan Medicine 67:19-23, 1968. Gudbjarnason, S., Braasch, W. and Bing, R.J.: Protein synthesis in cardiac hypertrophy and heart failure. p. 184. In: Heart Failure, Batho=sioloEical and Clilical Aspects. Editors H. Reindell, J. Keul and E. Doll. Publisher, Georg Thieme Verlag, 1968. Gudbjarnason, S, Braasch, W. and Bing, R.J.: Defective energy metabolism and fatty degeneration in heart muscle, p. 253. In: Heart FailurI;, Pathophysiological and Clinical Aspects. Editors, H. Reindell, J. Keul and E. Doll. Publisher, Georg Thieme Verlag, 1968. Robin E., Wendt, V. and Bing, R.J.a Special diagnostic procedures in cardiac surgery. In: Suraer_v of the Chest (2nd edition), Editors, Dr. John H. Gibbon, Dr. David C. Sabiston and Dr. Frank Spencer. W.B. Saunders Co. Philadelphia, London, Toronto, p. 573-6og, 1969. Cowan, C., Fard, M. and Bing, R.J.: The metabolism of heart muscle in health and disease. In: The Biolo ical Basis of Medicine. Academic Press, London, England, 6:1-13, 1969. Bing, R.J., Gudbjarnason, S., Tschopp, H., and Braasch, W.: Molecular changes in myocardial infarction in heart muscle. In: Ann. N.Y. Acad. Sci on Experimental "Metabolic" Cardiopathies and Their Relationshiv to Human Heart Diseass. Editors, E. Bajusz, Published by the Academy, New York, 156:583-593, 1969. Puri, P. and Bing, R.J.: Effects on myocardial contractility, hemo- dynamics and cardiac metabolism of a new beta-adrenergic blocking drug - Sotalol. Disease of the Chest. 55:235, 1969. Boettcher, D., Corsini, G., Daniels, C., Cowan, C. and Bing, R.J.: The determination of myocardial blood flow in the anesthetized dog following a slug injection of Rubidium-84. J. Nuclear Med. 10:2, 1969. Robin, E., Ravens, K.G. and Bing, R.J.: The effect of alcohol, nicotine and cigarette smoking on the heart. Deutsches Medizinisches Journal 1:19, 1969.

RICHARD JOHN BING, M.D. - 18 - • ft Martinez-Mojares, M., Gudbjarnason, S. and Bing, R.J.: Myocardial metabolism. In: Mondern Trends in Cardiolog,y (2nd edition), Butterworth and Co.,Ltd., London, England, pp. 160-177, 1969. Ravens, K., Gudbjarnason, S., Cowan, C. and Bing, R.J.: Gamma-glutamyl transpeptidase in myocardial infarction clinical and experimental studies. Circulation 39:693, 1969. Leb, G., Derntl, F., Goldschlager, N., Cowan, C. and Bing, R.J.: Deter- mination of effective and total coronary blood flow using Rubidium-84 Amer. J. Med. Sci. 257:203, 1969. Robin, E. and Bing, R.J.: Effect of alcohol upon.cardiac hemodynamics. In: Proceedings of the Symposium on Alcohol Metabolism, Wayne Stat_e University, Thomas Publishing Co., Springfield, Illinois. Chapter 28, p. 281, 1969. Goldschlager, N., Ravens, K.G., Leb, G., Cowan, C. and Bing, R.J.: Studies on effective capillary blood flow of the human and canine~ heart after acute myocardial infarction. Circulation. Vols. XXXIX a.nd. XL, Nov. 1969. Cowan, C., Duran, P., Corsini, G., Goldschlager, N. and Bing, R.J.: The effects of nitroglycerin on n~yocardial blood flow in man measured by coincidence counting and bolus injections of Rubidium-84. Amer. J. Cardiol. 24:154, 1969. Robin, E., Gudbjarnason, S., and Bing, R.J.: Biochemical phenomena of the myocardium during hypoXia. In: Drugs and Metabolism of Mvocardzum and Striated Muscle. Symposium Internationale. Edited by Lamarche, Nancy, France. 1969. Leb, G., Derntl, Robin E., and Bing, R.J.: The effect of nicotine on effective and total coronary blood flow in the anesthetized closed chest dog. Jour. Pharmacol. and Exp. Therap. Vol. 173, 1, November 20, 1969. Bing, R.J.: Nuovi Aspetti delle Cardiopatie Ischemische. Estratto do "La Riforma Medica" - Napoli - N. 11-1969, pp.3-11. Bing, R.J.: Myocardial metabolism in old age with particular reference to coronary artery disease. G. Gerontol 43:961, 1969. Puri, P.S. and Bing, R.J.: Effects of glucagon on myocardial contractility and hemodynamics in acute experimental myocardial infarction, basis for its possible use in cardiogenic shock. Amer. Heart J. Vol. 78, No. 5 pp. 660-668 Nov. 1969. Goldschlager, N., Robin, E., Cowan, C., Leb, G., and Bing, R.J.: The effect of glucagon on the coronary circulation in man. Circulation Vol. XI, December 1969.

RICHARD JOHN BING, M.D. - 19 - • Gudbjarnason, S. Puri, P., Cowan, C. and Bing, R.J.: Myocardial meta- bolism and blood flow. In: Methods in Pharmacology. Ed. Dr. A. Schwartz, Appleton-Century-Crofts. 1970. Bing, R.J.: The clinician vs the investigator or town and gown in cardiology. Amer. J.Cardiol. (editorial) Jan. 1970. Bing, R.J., Puri, P. and Gudbjarnason, S.: Clinical pharmacology in myocardial infarction. Article written by invitation of Society of Cardiology of the U.S.S.R. as part of a book on Cardiology celebrating the 70th anniversary of Professor Pavel E. Lukomsky, President of the above mentioned society 1970. Robin, E., Gudbjarnason, S. and Bing, R.J.: Direct and reflex effects of hypothermia, hypotension and hypoxia on the heart. iiahnem.ann Symposium 1969, pp.251-267. Puri, P.S., Alany, D. and Birig, R.J.: Effect of nicotine on contractility of the intact heart. Cardiology Digest, Vol. V. pp.19-25, Jan. 1970. Tillich, G., Mendoza, L., Bing, R.J.: Total and nutritional coronary flow. Circulation Res. (Supp. I) Vol. XRVII and XXIX Jan. 1971. Mendoza, L., Tillich, G., Bing, R.J., Wayland, H.: Studies of the coronary microcirculation of the cat. Amer. J. Cardiol 27:93, 1971. Tillich, G., Hellberg, K., Rickart, A., Mendoza, L. Bing, R.J.: - The Effect of intravenous ethyl alcohol on the coronary circulation and myocardial contractility of the human and canine heart. J. of Clin. Pharmacol. pp.165-176, May-June, 1971. Hellberg, K., Rickart, A., Wayland, H., and Bing, R.J.: Coronary microcirculation in the potassium chloride arrested heart. J. of Molecular and Cellular Cardiol. 2:221, 1971. Bing, R.J.: New aspects of coronary circulation. Symposium, Italian Biological and Physiological Society. Pages 1-22, 1971. Bing, R.J., Hellberg, K., Rickart, A.: Techniques to measure coronary blood flow in man. Amer. J. of Cardiol 29(11)75-80, 1972. Bing, R.J., Wayland, H., Rickart, A., and Hellberg, K.: Studies of the coronary microcirculation by direct visualization. Giornale Italiano Di Cardiologia l-4O1-408, 1971. Bing, R.J.: New aspects of the coronary circulation. Estratto dal Vol. XLVII, Fasc. 20 bis, del Bollettino Della Societa Italiana Di Biologia Sperimentale, 1971. Bing, R.J., Rickart A, Hellberg, K:Biochemie der Herzmuskelhypertrophie Verhandlungen der Deutschen Gesellschaft f~r innere Medizin 77. Band Mu.n.chen 1971.

ut • a RICHARD JOHN BING, M.D. - 20 - Bing, R.J., Hellberg, K., Wayland H.:Microcirculation of the Heart. In: Comparative Pathophysiology of Circulato Disturbances. Ed. Colzn7l°° oor. enum Publishing Corporation,New York. 1972. Page 253-266. Bing, R.J.: Seminar on the Coronary Microcirculation, Part I. American Journal of Cardiology, 29:591, 1972. Bing, R.J., Hellberg, K., Rickart, A., Wayland, H.: Studies on the Coronary Microcirculation by Direct Visualization. American Journal of Cardiology 29:591-597, 1972. Morita, T., and Bing, R.J.: Lipid Metabolism in Perfused Human Coronary Arteries. Proc. Soc. Exp. Biol. Med 140 (2):617-622, 1972. Bing, R.J.: Reparative processes in heart muscle following myocardial infarction. Joint Symposium of the International Society of Cardiology and the World Health Organization, Geneva 1971. In: Metabolism of the Hypoxic and Ischaemic Heart. S. Karger publisher (P. Moret and Z. Fejfar ed , page 31 324, 1972. Bing, R.J, Robin, E., Ganguly, S.N.: Cardiac catheterization. In: CHRISTOPHHER'S TEXTBOOK OF SURGERY. W. B. Saunders Co. (ed. D.C. Sabiston 10th edition, 1972. Bing, R.J., Hellberg, K.: Measurement of coronary flow in ischemic heart disease (edited by W. Likoff, B.L. Segal, W. Insull, Jr.). From the Hahnemann Symposium of Coronary Heart Disease. In: Atherosclerosis And Coronary Heart isease, Page 146. 1972 Grune & Stratton, Inc. Stefan G., and Bing, R.J.: Echocardiographic findings in experimental posterior myocardial wall infarction. Amer. J. Cardiol. Pachinger, 0., Heliberg, K., Bing, R.J.: The effect of nicotine propranolol, phentolamine, and hexamethonium on the coronary microcirculation of the cat. J. Clin. Pharma. 12:432, Dec. 1972. Bing, R.J., Hellberg, K.: Coronary blood flow in relation to angina pectoris. Circulation, Vol XLVI, page 1145-1154, December 1972. Bing, R.J., H. Wayland, A. Rickart, and K. Hellberg: Studies on the coronary microcirculation by direct visualization. In: . Njyocardial Bllod Flow in Mari: Methods- -and -Sign.;:f°icance-- ;:n -Cor-onar-y Disease (A. Maseri, ed). Minerva Medica, Torino, Italy. Page 23-35, 1972.

RICHARD JOHN BING, M.D. - 21 - Bing, R.J.: Comments on the use of cdncidence counting for myocardial blood flow estimates by the fractionation method. In: Methods and Significance in Coronary Disease (A. Maseri, ed). Minerva Medica, Torino, Italy. Page 193-1 , 1972. Bing, R.J.: Comments on the adaptations of myocardial oxygenation and metabolism to ischemia. In: Methods and Significance in Coronary Disease (A. Maseri, ed). Minerva Medica, Torino, Italy, 1972. Pachinger, 0., Tillmanns, H., Bing, R.J.: Coronary blood flow assessment with xenon and rubidium. Seminars in Nuclear Medicine, 3:131-138 (April), 1973 (No.2). Pachinger, 0., Mao, J., Hashimoto, H., Hellberg, K., Tillmanns, H., Bing, RJ: The effect of prolonged administration of ethano~ on cardiac metabolism and performance in the dog. J. Clin. Invest 52:2690-2696, 1973. Bing, R.J.: From Organisms to the Cell: The history of Metabolism. Presidential Address, Winnipeg, Canada. University Park Press 5th Annual meeting of the International Study Group for Research in Cardiac Metabolism, 1972. Hashimoto, H., Tillmanns, H., Sarma, J.S.M., Mao, J., Holden, E., Bing, R.J.• Lipid Metabolism in perfused hlunan nonatherosclerotic coronary arteries and saphenous veins. Atherosclerosis, 19:35-45, 1974. Ishikawa, K., Sarma, R., Getzen, J.H., McNair, J.D., Cosby, R.S., Buggs, H., Johnson, J.L., Bing, R.J.: Reduction of myocardial contractility by 100% oxygen in patients with coronary disease. Proc. Soc. Exper. Biol. & Med. 145:99-102, 1974. Bing, R.J., Tillmanns, H.: Umweltfaktoren und Herz. Therapie Woche 24: 6, 560 1974. Tillmanns, H., Fauvel J-M, Hansen H., Sarma JSM, Bing, R.J.: Microcirculation in the ventricle of the dog and turtle. Circulation Research 34:561-569, 1974. Bing, R.J., Bender S.R., Dunn, M.I., Fry, G.A., Fuller, W.M. Liu, S.C.K., Miller, H.S., Moses J.W. Ritzman, L.W.,Segal, J.P. Shugoll, G.I., Wallac, A.: Double-blind Crossover Study of Intensain. Antianginal effects of chromonar: A combined Invesitgation. J. Clin. Pharm. & Therapetuics 16:4-13, No. 1, Part i 1974. S

-22- T S Bing RJ, Rickart A, and Hellberg K: Reversibility of changes produced by myocardial ischemia. Symposium by the United States Navy and the University of Miami. University Park Press. Bing RJ, Wayland H, Rickart A and Hellberg K: Studies on the coronary microcirculation by direct visualization. Russian Journal of Cardiology, 1971. Bing RJ, Pachinger 0, Agnew WF, Mao J, Hashimoto H, Yuen T and Tillmanns H: The effect of alcohol on the dog's heart: A model for heart failure. Symposium in honor of Professor Parin, Institute of Normal and Pathological Physiology, USSR. Published in "Actual problems of physiology and pathology of circulation", monograph for Russian Academy of Science, 1973. Bing RJ, Bender SR, Dunn MI, Fry GA, Fuller WM, Lieu SCK, Miller HS, Moses JW, Ritzmann LW, Segal JP, Shugoll GI, Wallace A: Double-blind crossover study of Intensain. Antianginal effects of chromonar: A combined investigation. J. Clinical Pharma. & Therapeutics 16:4-13, 1974. Bing RJ, Tillmanns H: Cardiac Metabolism. Cardiologia d'Oggi ("Cardiology Today"), C.G. Edizioni Medico Scientifische, Italy, ed. bv V. Puddu and A. B. Anguissola, Vol. 2, 1974. Bing RJ, Tillmanns H, Fauvel JM, Seeler K, Mao JC: Effect of prolonged alcohol administration on calcium transn_ort in heart muscle of the dog. Circ. Res. 35:33-38, 1974. Sarma R, Ishikawa K, Getzen JH, McNair JD, Buggs H, Johnson JL and Bing RJ: Comparison of the invasive and noninvasive measurements in coronary artery disease. Cardiology 59:114-122, 1974. Bing RJ, Tillmanns H, Ikeda S: Production of myocardial infarctions in animal experiments. German Handbook of Experimental Pharmacology. Springer-Verlag, 16:117-130, 1975. Sarma JSM, Tillmanns H, Ikeda S and Bing RJ: The effect of carbon monoxide on lipid metabolism of human coronary arteries. Atherosclerosis 22:193-198, 1975. Bing RJ, Tillmanns H, Ikeda S: Metabolic Effects of Alcohol on the Heart. From Symposium for the National Council on Alcoholism in Denver, Colorado. Ann. N. Y. Acad. Sci. 252:243-249, 1975. Bing RJ: Atherosclerosis and Metabolism of the Arterial Wall. Symposium in Am. J. Card. 35:541, 1975. (Introduction) Sarma_ JSM, Tillmanns_ H, Ikeda_ S., . Grenier_ A, ColbyE E and_ Ring RJ:. _._Lipidd metabolism in perfused human and dog coronary arteries. Am. J. Cardiol. 35:579-587, 1975.

V - 23 - Bing RJ and Sarma JSM: In Vitro Inhibition of Cholesterol Uptake in Human and Animal Arteries by 7-Ketocholesterol. Biochem. Biophys. Res. Comm. 62:711, 1975. Yoganathan AP, Gupta R, Udwadia FE, Miller JW, Corcoran WH, Sarma R, Johnson JL and Bing RJ: Use of the fast fourier transform for the frequency analysis of the first heart sound in normal man. Med. Biol. Engin. p. 69, Jan., 1976. Bing RJ and Tillmanns H: Radioisotopic measurements of coronary blood flow. In: Diagnostic Methods in Cardiology, Cardiovascular Clinics, pp. 28-52, 1974. Ishikawa K, Buggs H, Sarma R, Tillmanns H, Fauvel JM, Getzen JH, Johnson JL and Bing RJ: Blood flow velocity in the carotid artery as a measure of myocardial contractility. Jap. Heart J. 16:22-35, 1975. Ikeda S, Duken H, Tillmanns H and Bing RJ: Coincidence counting and noncoincidence counting (81Rb and 43K): A comparative study. J. Nucl. Med. 16:658-661, 1975. Sarma JSM, Tillmanns H, Ikeda S and Bing RJ: The effect of carbon monoxide on lipid metabolism of human coronary arteries. Atherosclerosis 22:193-198, 1975. Bing RJ: Metabolic changes in myocardial infarction. Editorial. Ain. J. Cardiol. 36:974, 1976. Sarma JSM, Fischer R, Ikeda S and Bing RJ: In vivo inhibition of cholesterol uptake in rabbit aortas by 7-Ketocholesterol. Proc. Soc. Exper. Biol. Med. 151:303, 1976. Bing RJ et al.: Metabolic fate of ingested and injected 7-ketocholesterol in the intact rabbit. Artery 2:153, 1976. Bing RJ: The Course and Science of Cardiac Metabolism, Circ. Res. 38:151, 1976. Bing RJ, Sarma JSM, Fischer R and Ikeda S: Mechanism of inhibition of cholesterol uptake by the arterial wall. In: Atherosclerosis Drug Discovery (1976), edited by Charles E. Day, Plenum Press, New York, p. 419. Bing RJ and Tillmanns: Cardiac Metabolism. In: Cardiologia D'Oggi (Cardiology Today), Vol. 1, pp. 9-27, 1974. Sarma JSM, Ikeda S, Fischer R, Maruyama Y, Weishaar R and Bing RJ: Biochemical and contractile properties of heart muscle after prolonged alcohol administration. J. Mol. Cell. Cardiol. 8:951-972, 1976.

c • -24- Bing R.J., Sarma J.S.M., and contractility of the Germany, 1976. Bing R.J. and Fis cher R: radioactive potassium or coronary artery disease. July 1, 1976). Fischer R., Maruyama Y, and Weishaar R: Biochemistry infarcted heart. Third Kolner Symposium, Cologne, Evaluation of myocardial blood flow determined with rubidium and precordial counting in relation to Herz 2:8-10, 1977. (Presented in Munich, Germany, Sarma J.S.3+7., Ikeda S., Fischer R., Maruyama Y., Weishaar R. and Bing R.J.: Biochemical and Contractile Properties of Heart Muscle after prolonged Alcohol Administration. J. Mol. Cell. Cardiol. 8:951-972, 1976. Fischer R., Ikeda S., Sarma J.S.M. and Bing R.J.: Effect of indomethacin, 6-hydroxydopamine, Saralasin, and hemorrhage on renal hemodynamics. J.Clin. Pharmacol. 17:5-12, 1977. Cardiology 62: 2-20 (1977) Weishaar R., Sarma J.S.M., Maruyama Y., Fischer R. and Bing R.J.: Regional Blood Flow, Contractility and Metabolism in Early Myocardial Infarction. Weishaar R., Sarma J.S.M., Maruyama Y., Fis cher R., Bertuglia S., and Bing R.J.: Reversibility of mitochondrial and contractile changes in the myocardium fol- lowing cessation of prolonged ethanol intake. (Am. J.of Cardiology 40:556,1977). Bing R.J. and Tillmanns H.: The effect of alcohol on the heart. In: Metabolic Aspects of Alcoholism (Charles S.Lieber, ed.), Chap.4, pp.117-134. MTP Press Lim~te T, St.Leonard's House, St.Leonardgate, Lancaster, 1977. Sarma J.S.M. and Bing R.J.: The inhibitory effect of 7-ketocholesterol on the cholesterol uptake by the arterial wall. J.Mol. Cell. Cardiol. 10:197-204, 1978. Maraxyama Yukio, Sarma J.S.M., Fischer Renate, Bertuglia Silvia, Bing Richard J.: Effect of alcohol on the contractile and elastic properties of glycerinated heart muscle from rats. In: Currents in Alcoholism, Volume III (Frank A.Seixas,M.D. ed.), (C) by Grune & 6tratton Inc. 1978. Sarma, J.S.M., Tschurtschenthaler, Gertraud V., Bing, Richard J.: "Effect of High Density Lipoproteins on the Cholesterol Uptake by Isolated Pig Coronary Arteries" Artery 4(3):214-223 (1978). Weishaar Ron, Bertuglia Silvia, Ashikawa Kouichi, Sarma J.S.M. and Bing Richard J.: Comparative Effects of Chronic Ethanol and Acetaldehyde Exposure on Myocardial Function in Rats. Journal of Clinical Pharmacology,Vol.18, pp.377-387 Aug-Sept.1978, Bing, Richard J.: Cardiac Metabolism its contributions to Alcoholic Heart Disease and Myocardial Failure. Circulation 58:6, December 1978. '

-25- 0 Yukio Maruyama, Richard J. Bing, J. S. M. Sarma and Ronald Weishaar. The effect of alcohol on active and passive stiffness, and on isometric con- tractions of glycerinated heart muscle in rats. Japanese Heart Journal, July 1978, Vol. 19. No. 4 pp. 513-521. R. J. Bing, J. S. M. Sarma, and S. I. Chan. Inhibition of Cholesterol Uptake by the Arterial Wall in the Intact Animal. Artery. 5(1): 14-28 (1979). Ronald Weishaar and Richard J. Bing. The effect of Diltiazem, a calcium- antagonist of myocardial ischemia. Amer. Jour. Card. 43:6, 1137-1143 (1979). Weishaar, Ronald, Tschurtschenthaler, Gertrand V., Ashikawa, Kouichi, and Bing, Richard J.: The relationship of regional coronary blood flow to mitrochondrial function during reperfusion of the ischemic myocardium. Cardiology 64:350-364 (1979). Report to Congress on Alcohol and Health, Chapter III, No. 5, pp 109-117, June 1978. "Alcohol and the Heart" Published by the U.S. Dept. of Health, Education and Welfare. ed. Ernest P. Noble, Ph.D., M.D. R. J. Bing, J. S. M. Sarma, R. Weishaar, A. Rackl, and G. Pawlik: Biochemical and histological effects of intermittent carbon monoxide exposure in cynomolgus monkeys (Macaca Fascicularis) in relation to atherosclerosis. Jour. Clin. Pharmacology. G. Santillan, J. S. M. Sarma, G. Pawlik, A. Rackl, A Grenier and R. J. Bing. Toxicity, Pharmacokinetics, and Cholesterol Inhibitory Effect of 7-Keto- cholesterol. Atherosclerosis, 35 (1980) 1-10. Richard J. Bing, Ronald Weishaar, Angelika Rackl and Gunter Pawlik: Mechanisms of antianginal drugs. A chapter In: Ischemic Myocardium and Antiaginal Drugs (Perspectives in Cardiovascular Research, Vol. 4). M. S. Winbury, ed. Santillan, G. G., Schuh, J. R., Rackl, A., Pawlik, G., Grenier, A., and Bing, R. J. Lipoprotein uptake in perfused arteries: Inhibition by 7-ketocholesterol. Artery. Richard J. Bing. "Action of Anti-Anginal Drugs on Cardiac Metabolism" In: Advances in Myocardiology, Vol. 2. R. J. Bing, G. V. Tschurtschenthaler, R. Weishaar and K. Ashikawa. The relation- ship of regional coronary flow to mitrochondrial function during reperfusion of the ischemic myocardium. Brain and Heart Infarct II. Eds. K. J. Zulch, W. Kaufmann, K. A. Hossman, V. Hossmann. Springer-Verlag, Berlin, Heidelberg. 1979. Ronald E. Weishaar and Richard J. Bing. The beneficial effect of a calcium channel blocker, Diltiazem, on the ischemic-reperfused heart. Journal of Molecular and Cellular Cardiology.- (1980) 1.2, 993-1009. R._ J.._Bi2_i.g_and. R. Weishaa_r, "Some aspects of myocardial metabolism during acute ~ infarction" In: Proceedings, Vol. II of Florence International Meeting on Myocardial Infarction. Italy, pp. 515-514, May 8-12, 1979.

L . S -26- G. Santillan, J. S. M. Sarma, G. Pawlik, A. Rackl, A. Grenier and R. J. Bing. "Toxicity, Pharmacokinetics, and Cholesterol Inhibitory Effect of 7-Keto- cholesterol. Atherosclerosis. 35 (1980) 1-10. Yukio Maruyama, Renate Fischer, Richard J. Bing. "The effect of regional myocardial ischemia on series elastic and contractile elements of glyceri- nated heart muscle in dogs," Japanese Circulation Journal, Vol. 44, No. 6, June 1980, pp. 449-460. G. G. Santillan, J. Schuh, S. I. Chan, and R. J. Bing. "Binding and inter- nationalization of low density lipoproteins by perfused arteries," Biochemical and Biophysical Research Communicatons. Vol. 95, No. 4, pp. 1410-1416, 1980. A. Rackl, G. Pawlik, and R. J. Bing, "Cerebral Capillary Topography and Red Cell Flow in Vivo," In: Advances in Neurology-Cerebral Microcirculation and Metabolism. In press. G. Pawlik, A. Rackl, R. J. Bing, "Quantitative:Capillary Topography and Blood Flow in the Cerebral Cortex of Cats: An in vivo Microscopic Study" In Brain Research, 208 (1981) 35-58. (Elsevier/North-Holland Biomedical Press) R. J. Bing and R. E. Weishaar: Cardiovascular Disease in the Alcoholic. In: Medical Consequences of Alcohol Abuse. Eds. P.M.S. Clark and L. J. Kricka. Chapter 8, pp. 76-84. 1980. Richard J. Bing: Cardiac Metabolism. In: Cardiac D iagnosis and Treatment (Third Edition) Ed. Noble 0. Fowler, pp. 281-296, 1980. G. G. Santillan, J. R. Schuh, S. I. Chan, and R. J. Bing: Lipoprotein uptake in perfused arteries: Inhibition by 7-ketocholesterol. Artery 7 (5): 384-394 (1980). , R. J. Bing, A. Rackl, G. Pawlik "Schwerpunkte der internationalen kardiologischen Forschung" In Therapiewoche 31, 233-243 (1981). Verlag G. Braun, 7500 Karlsruhe 1. Richard J. Bing. Personal memories of cardiac catheterization and metabolism of the heart. In: History and Perspectives of Cardiology Catheterization, angiography, surgery and concepts of circular control. Proceedings of the Eithoven meeting held at Leiden University, Nov. 1-3, 1979. Eds. H. A. Snellen, A. J. Dunning and A. C. Arntzenius. Bing-Lo Chang, Takashi Yamakawa, Jill Nuccio, Ron Pace and Richard J. Bing: Microcirculation of left atrial muscle; cerebral cortex and mesentery of the cat: A comparative analysis. Circulation Research. 50, 240-249, 1982. Richard J. Biin.g. Effect of alcohol on the heart and cardiac metabolism. Federatiori Proceedings, June--1982:- Voi.- 41; No: 7; Pg~ -2443 =2446. Richard J. Bing. New Aspects of International Cardiac Research. Memorial address for Dr. Wilhelm Lochner. (1979)

4 • S • -27- M. Sato, M. Ohashi, M. Z. Metz and R. J. Bing. Inhib itory Effect of a Calc ium Antagonist (Diltiazem) on Aortic and Coronary Contractions in Rabb its. J. of Mole. and Cell. Card. (1982) 14, 741-744. Gregorio G. Santillan, Irene Zak and Richard J. Bing. Incorporation of 7-Ketocholesterol by Plasma Membranes from Porcine Aortic Endothelial Cells. Artery 11(12):119-135 (1982). R. J. Bing, Bing-Lo Chang, G. Santillan and M. Sato. The effect of 5-hydroxytryptamine.and arterial blood withdrawal on cerebral microcirculation in the cat, arterial permeability in the rabbit. Advances in Experimental Medicine and Biology, Vol. 161, p. 327, 1983. R. J. Bing, and Bing-Lo Chang. The action of Diltiazem on Vascular Smooth Muscle and on protection of the ischemic (dog) and isch.emic reperfused (rat) heart. In Fleckensteins's 65th Birthday Celebration Volume (1983). Holistic Medicine: A View from the Fence, by Jerome D. Frank, MD; FOREWORD by Dr. Richard J. Bing; April 1983. Richard J. Bing and Bing-Lo Chang. Microcirculation in Myocardium and Cerebral Cortex. From: Heart Perfusion, Energetics, and Ischemia. Plenum Publishing Corp., p. 157-178, 1983. Richard J. Bing, The Biochemical Basis of Myocardial Failure. A featured article from the September issue of Hospital Practice. p. 93-112, 1983. Richard J. Bing, "Carrel; A Personal Reminiscence. JAMA, Dec. 23130., 1983 Vol. 250, No. 24, p. 3297-3298. Chang, B.L., Santillan, G., and Bing, R. J.: Red cell velocity and auto- regulation in the cerebral cortex of the cat. . Brain Research, Vol. 308, p. 15, 1984. Bing, R. J.: Differential therapy of heart failure. Bayer AG, Leverkusen 1984 (Ed.: R. Alstaedter, M.D.) pp. 58-61. Santillan, G. G., Sato, M., and Bing, R. J.: Effect of serotonin on albumin and low density lipoprotein uptake in perfused rabbit femoral arteries. Angiology, Vol. 35, No. 11 (November) 1984. Bing, R. J.: 'Cardiac perfusion, past and present. Plenum Press, 1984. Bing, R. J., Burger, W., Chemnitius, J. M., Sugihara, J., and Navas, R.: The effects of a new cardiotonic drug (TA-064) on normal and failing heart prepara- tions. 'Current Therapeutic Research, Vol. 36, No. 1, July 1984, pp. 133-147. Bing, R. J., Sasaki, Y.,'Chemnitius, M., and Burger, W.: 'Compartmentation and functional mechanisms in myocardial failure and myocardial infarction. Plenum Press, 1984. Bing, Richard J., and Vander Laan, Thomas L.: New drugs for heart disease. 'Chapter 5 in Frontiers in Medicine, 1984.

ts • -28- Feinstein, S. B., Shah, P. M., Bing,, R. J., Meerbaum, S., 'Corday, E., `Chang, B-L., Santillan, G., and Fujibayashi, Y.: Microbubble dynamics visualized in the intact capillary circulation. JACC, Vol. 4, No. 3, 1984, pp 595-600. Burger, W., Chemnitius, J. M., Metz, M. Z. and Bing, R. J.: A model for the study of coronary spasm induced changes in cardiac metabolism. Accepted by J Mol Cell Cardiol, 1984. Chemnitius, J. M., Sasaki, Y., Burger, W. and Bing, R. J.: The effect of ischemia and reperfusion on sarcolemmal function in perfused canine hearts. Accepted by J Mol Cell Cardiol, 1984. Bing, R. J., Sasaki, M. S., Burger, W. and Chemnitius, J. M.: Cardiac inotropic response of a new ~-1-agonist (TA-064) with low sarcolemmal adenylate cyclase activation. Curr Therap Res 36, no. 6 (December), 1984. Burger, W. Chemnitius, J. M. and Bing, R. J.: A new method for the visualization of subepicardial coronary arteries in small isolated mammalian hearts. Proc Exp Biol Med (in press), 1984.