Tobacco Documents Online

1 STATUS REPORT ON THE AMERICAN HEALTH FOUNDATION, JUNE 1971 A. Facilities B. Organization 1. Five Divisions a. Epidemiology b. Environmental Toxicology c. Nutritional Biochemistry d. Theoretical Biochemistry e. Experimental Biology and Pathology Preventive Medical Examination Clinic: PMX C. Funding, including letter from R. E. Coleman, copies of pages from 1970 3 Directory of On-Going Research in Smoking and Health. D. Literature - 1. American Health Foundation: Proposed Center of Public Health Action 10 a. General Summary b. Exhibit A Health Motivation Committee 21 c. Exhibit B Public Health Action Committee 22 d. Exhibit C Reprint: The Epidemiology of Lung Cancer, Wynder, E.L., 23 Mabuchi, K., Beattie, E.J. J.A.M.A., 2221-2228 (1970). e. Exhibit D Committee on Food and Nutrition 31 f. Exhibit E "Preventive Medicine" Advisory Board, Editorial Board 32 g. Exhibit F The American Health Foundation Newsletter 35 h. Exhibit G Center for Public Health Action, Division of Health 51 Education and Motivation, Division of Health Care including Nutrition Clinic, Smoking Withdrawal Clinic, Physical Fitness Clinic i. Exhibit H Health Surveillance Committee 52 j. Exhibit I Sample Budget for Center for Public Health Action 53 2. Reprint: The American Health Foundation, George James, Arch. Envir. Health 21, 84-85 (1970) 3. Reprint: Dr. Wynder to Direct New American Health Foundation, Tob. Reporter (1969) 4. Public relations Folder: Statement of Purpose 5. Photographs: Board of Trustees, Scientific Consultants. E. Ahrens is no longer listed on the Board.) (Note: Dr. 6. Biography, Ernest L. Wynder 54 56 57 65 68 E. Comment, Overview 69

A. Facilities In November, 1970, the American Health Foundation moved from 180 East End Avenue to the less prestigeous 2 East End Avenue, seventh floor. The reception area is in front of the office and laboratory space. Total area is estimated at 14,000 square feet, of which 10,000 feet or so is laboratory space and animal quarters (rats, mice and hamsters). B. Organizational Structure 1. Five Divisions a. Epidemiology: Directed by Ernest L. Wynder, M.D. Intramural: Health interviews are being carried out in eight Manhattan and one Bronx hospital. Mainly cancer patients: comparisons of living habits and other data between lung cancer patients and bladder cancer "control" patients, i.e., not associated with smoking. Also large intestinal cancer patients and a study to compare data on coronary versus stroke patients. The amount of retrospective and prospective approach is not certain, but emphasis is on the latter. Extramural: Dr. Lester Breslow of U.S.C. is listed as a member of the Board of Consultants. The amount of collaboration is not clear. Also Dr. Hoffman claims they have two interviewers in Houston. These patients are to be interviewed about their background and social habits. New York will be the center for the computer analysis (they will rent compute time "when the data is ready"). How far this program has gone is not clear. Funding is the question. b. Environmental Toxicology: Directed by Deitrich Hoffman, Ph.D. This intramural program carries on the back painting with tobacco condensate, feeding of different diets in relationship to heart disease, large bowel.cancer (naptholamines), and tissue culture experiments ("for more sensitive assays") under Dr. Po Chan. Mr. Gunther Ratkamp is a technical staff member in this area. Blood clotting studies of tobacco and carcinogenesis is through USDA (see funding section). c. Nutritional Biochemistry: No head assigned. Peter Hill, Ph.D. Projects not clear and no funding evident. Interests are in DDT, DDE, methyl mercury, marijuana. d. Theoretical Biochemistry: No one assigned yet. Extramural program (a very vague collaborative association) is under Dr. Wilk in Frankfurt, Germany. e. Experimental Biology and Pathology: Directed by Bing T. So, M.D. No projects or funding yet.

a 3 2. Preventive Medical Examination Clinic: PMX Intramural: Dr. Wynder has proposed an early diagnostic clinic similar to the Kaiser Permanente program in California. The proposal is attached. There is no funding or active program to date. This program was to carry out physical examinations for industrial concerns at about $50.00 per examination. The health data from this "well studied" population would be computerized for later retrieval and analysis. Extramural: As originally conceived, there would be five collaborating PMX centers, one of which would be under Dr. O'Doyle of George Washington University. Others to be involved, as stated in a file note - unconfirmed - were Drs. Emerson Day, Henry Selby, Maurice Shills, James H. Terry; Paul Sherlock, Donald Davis. These groups have not developed to any defined degree; personnel are not assigned. Other activities relating to the PMX include the development of activist external advisory committees, to give advice to the government, public health agencies and industry. These committees include: a. Nutrition: Frederick J. Stare, M.D. of Harvard b.• Physical Fitness: Kyle Rote, sportscaster c. Smoking Withdrawal: No head. d. Hypertension: No head. C. Funding The following sources of funding were listed by the American Health Foundation. Of course it must be realized that this organization has an ongoing fund-raising program, receiving money from private sources, little old ladies and,. presumably, being listed on.the Board(s) probably entails a commitment to contribute. 1. Health Research Council of the City of New York: Currently no funds. 2. 3. American Cancer Society: Currently no funds. Effective July.l, Dr. Deitrich.Hoffman will receive $40,000 for a one-year study entitled Experimental Tobacco Carcinogenesis. National Institutes of Health: Currently and during 1970-71 no funds. Confidential inquiry has disclosed that Dr. Werner Taupp has applied for a grant which will be reviewed at the Hune Council of the NCI. Funding, if approved, would not be before late fall 1971 or spring 1972. Previously, while at Sloan Kettering Institute, Dr. Wynder was listed, along with a number of other researchers, on the large $5-million "Block Grant" which stirred up some controversy earlier this year. This money was cut off when Wynder left Sloan Kettering, and will terminate anyway December 31, 1971.

U.S. Department of Agriculture: D. Hoffman and E. L. Wynder have two grants through the Agricultural Research Service, Plant Science Research Division (Beltsville, Md.) supervised by Dr. T. S. Tso of USDA under Dr. E. L. Moore, Chief of Tobacco and Sugar Crops Research: #12-14-100 10283 (34) #12-14-100 10295 (34) The latter grant is incorrectly listed as #10238(38) in the 1970 Directory of On-Going Research in Smoking and Health, published by HEW. See attached letter from R. E. Coleman and copies of pages from the 1970 Directory of On-Going Research in Smoking and Health. The amount of funds in these two projects was estimated in the $30-40,000 per annum range, but further information could be obtained by additional inquiry since this is public information. Copies of the proposals are also available.

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