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L-dopa goes into national distribution L-dopa the antiparkinson agent, went into national distribution last week when Roche Labs announced that it harl stockpiled enough of it~, Larcidrrpa to make it available for general prescription use throughout the 1-. ti. 11eanm•hile, Eaton Labs said it will start general distribution of its I.-drrpa prodtut, D>par, on or ahmut September 1 5 . t ntil nuw, the t-wo companies made the drug available only to hos- pitals and nursing honies where L-dopa had been administered on a test basis before approval to mar- ket the drug was given to the firms by the Forui and Drug Administra- t1o11. The<e hospitals and nursing honles were assured a continuing supply of the drug, because once a patient i~ started on an L-dopa regi- men he must continue on it to pre- vent relapse. For this same reason, the cotn- panies had to stockpile the drug to insure adequate supplies once it went into national distribution. A spokesman for Eaton told AMExT- cn N Dx, a:ossT that a pharmacist will still not be able to order a "w•hole backrocm full" of L-dopa. "Our first obligation," he said, "is to the patients already on the drug." Because of this, he continued, Eaton nta}• limit the quantities that an IZx- 91an can order. A Roche spr,kesman said that his company "is prepared to fill all legi- timate ordc•r~." DMSO okayed for horses The Food & I)rug Administra- tion has given Syntex clearance to market dirnethvl sulfoxide (DN1SU ) for use by veterinarians. The drug is applied topically to re- duce,,ac,ute swelling associated with traunia in horses'. NEW SPECIALTIES... Products in this section incfude: Arand new Menu .,, as well as new potencies or new do.ape forms or rer'u•d formulas of if.mi aiready on the nrarkN. Coly-Mycin :%l 1'arenteral ( \\•ar- ner-Chilcott ) I{ DESCRIPTION : An antibiotic for treatment of the severe, acute, and resistant chronic infections due to gram negative organisms. This ne.v dosage form is available in 2 strengths-20 nlg and 150 mg per vial-and is intended for intra.•e- nous as well as intramuscular ad- ministration. I)ocAcE : As directed. PwrxArt xa : \-ials with color- coded caps. Kinesed ( Snlart 1 H DFSCRiPTlo1 : A combination an- tispasmodic / sedative / antifiatulent for treatment of the h.•peractive and spastic bowel. Each fruit-flavored che.vable tablet contains 16 mg. phenoharbital : 0.1 tng. h}•osc.•amine sulfate : 0.02 mg. atropine sulfate : 0.007 nig. scopolamine hydrobro- mide : 40 mg. simethicnne. Dos.4cF : As directed. PACKAGING: Bottles of 100 and 500. Pyopen ( lieechanl ) I; DESCRIPTION : A new sen-ii-svn- thetic penicillin, carbenicillin, which is used in the treatment of infecticns A. O. IEGEND A. .. -14.ads refriyerotion ~ ...... 'Rx only' product fl ...Moy be sold w/o Rx ~ . . , . , .Narcotic product ~ . Narcotic (orol Rx OK) e ...... Exernpt Narcotic ® ........ Doted product caused by certain E. coli strain> re- sistant to other antibiotics and by Pseudonlona~ organism.. The drug is aclniinistered intravennrn~,l~ ar.rl intraniuscularly. 1)osAGE : As directed. PnchAGt:<c~ :\-ials (d I and : gm Veetids Oral Solution and Tahlet~, ( Syuibb ) It DESrRIrTtON : Available a~- ur<r' solutiom or tablets-each in 2 strengths. Veetids "L'" for ora: solution contain. 125 nig l,ruct~~,imii phenox)•nieth.•l petticillin per ; cc. \-eetids "2;0" fur oral srrlutinn hr: 2.;0 mg potassitnn phenrrxymethNl penicillin per 5 cc. \-eetids "_'5(i" tablets contain 250 mg puta>sium phenoxymethyl penicillin per tablet. \-eetids "500" tablets have ;0(} mc potassitnn phenoxymetly1 penicillil; per tablet. DosAcr : A, directecl. PAchactNr, : Oral .uln:ir m a\<ril- able in 100 cc and 200 cc bo;tle,: tablets in hottle~- of 1(N1. NEW RESEARCH... Amylopectin sulfate: Lowered recurrence rate in duodenal ulcer patients to IG1/( . When combined with propantheline the rate dropped to 137e. This compares to a recur- rence of 75% in a placebo group. By Drs. 1). C. H. Sun and '.N1. L. Ryan. VA Hospital, Phoenix, Ariz. Chlorpropamide: Treated stlc- cessfully 4 patients with idiopathic diabetes insipidus for as long as 11) months. By Drs. C. Thiffault, al. Trembla}', and G. Aubin, Hopital de St. Sacrement, Quebec. CL-1848C: Produced safe anes- thesia in 13 medical stuelent volun- teers when administered in a do~,e of 0.25 mg to 0.75 mg per kg body weight intra.•enously. Ten of the l'a volunteer~ reported havin;- YiN•id dreanls while under anesthesia from the drug• but none sssi(l that the dreams represented a threat it) their secnrit\. C)ne patient experienced a 1>anic state. Thi., was the unlh- side effect ohserved. By 1)r. Roy 1). \\'il- sun and assr,ciates, V of Texas. '~tec),jic{cl liirancll, t,,;ctl~rlstr,j~'' 6 AMERICAN DRUGGIST 0 Seprember 7, 1970 Phormocrul,cnf & MecLcn' ScIrnce • 57