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Brown & Williamson

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Date: 11 Mar 1980
Length: 1 page
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Named Person
X/Science
Type
NOTE, NOTE
NOTES
Characteristic
MN Selected
Date Loaded
23 Nov 1998
Litigation
10004026
10004042 10438
Request
F59
M128
Original File
Gori, Dri. Gio (Limited)
Attachment
2090
Recipient
Hughes, I.W.

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I Received M~R 1 ~ ig~g C. The paper is only an initial skeleton; references are being added . Two ways of ranking are given : one by emphasizing nicotine, the other by straight summation . As you can see, the picture changes somewhat . I am working on alternate ways, keeping in mind that we cannot deviate much from previous publications, without penalizing credibility . I enclose the Science paper of 1976, the last reference of which gives a formula for determining % plasma COHb, based on daily consumption and yield of CO per cigarette . Since nicotine has a half life of some 30 minutes, I am trying to see whether a cumulation algorithm for nicotine might give results in a desirable direction . Should have some idea by the time we meet this coming thursday . All the best . March II, 1980 &1

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