Bliley TI
[Record of Panel Meeting on Smoking and Health: Includes Industry and anti-Industry Positions]
Abstract
Record of panel discussion on smoking and health. Argues back-and-forth whether a link exists for smoking and disease. Questions impact of stress and disease. Examines viruses and cancer. Offers statistical examination of smokers, nonsmokers, and lung cancer. Argues that there is no causal link.
Fields
- Notes
(indexer.indexer_email WAS INVALID IN OLD DATABASE: JL)
- Company
- TI
- Type
- SCRIPT
- Region
- Japan
- Philadelphia
- United States
- Sweden
- France
- Named Person
- Aviado, Domingo M., M.D. (CTR Consultant; Special Projects Recipient)Dr. Aviado was a University of Pennsylvania professor and did work for tobacco companies. Dr. Aviado did secret dog inhalation studies in 1970s which were apparently covered up. Dogs were inhaling. No research papers were ever done, apparently (B.C. 7/7/94).
- Brownlee, A. (M.A.)
- Burch, P (Ph. D.)
- Cedarlof, R. (Ph. D.)
- Furst, A. (Ph. D.)
- Hammond, (Sc. D.)
- Langston, H. (M.D.)
- Levine, E. (M.D.)
- Meier, H. (D.V.M.)
- Ober, W. (M.D.)
- Ratcliffe, Hebert (CTR Special Projects Researcher)Industry-funded scientist, investigated lung cancer and cardiovascular disease in zoo animals, especially those maintained in an outdoor environment.
- Rosenman (Dr.)
- Seltzer, C. (Ph. D.)
- Selya, H. (M.D.)
- Selye (Dr.)
- Author
- Aviado, Domingo M., M.D. (CTR Consultant; Special Projects Recipient)Dr. Aviado was a University of Pennsylvania professor and did work for tobacco companies. Dr. Aviado did secret dog inhalation studies in 1970s which were apparently covered up. Dogs were inhaling. No research papers were ever done, apparently (B.C. 7/7/94).
- Brownlee, K. A.
- Burch, P.
- Cederlof, R.
- Furst, A. (Jr.)
- Hammond, E. C. (Jr.)
- Langston, H. T. (Jr.)
- Levine, E. R. (Jr.)
- Meier, H. (Jr.)
- Ober, W. B. (Jr.)
- Ratcliffe, Hebert (CTR Special Projects Researcher)Industry-funded scientist, investigated lung cancer and cardiovascular disease in zoo animals, especially those maintained in an outdoor environment.
- Rosenman, R. (Jr.)
- Seltzer, C.
- Named Organization
- American Cancer Society
- Council for Tobacco Research
- Harold Brunn Institute of CV Research
- Harvard University of Public Health
- Institute of Chemical Biology
- Institute of Experimental Medicine
- National Heart and Lung Institute
- National Institute of Public Health
- New York Medical College
- University of Chicago
- University of Illinois College of Medicine
- University of Pennsylvania
- Subject
- Health Effects
- lung cancer
- Nonsmokers
- Statistical Data
- tobacco use
- cancer
Document Images
'"SMOKING AN~., HEALTH: THE ,NEED T__O MOW"
NARRATOR: This is America today--the pace fast...the
competition great. We live with more tension, more
emotion, more concern about our health, more everything
than ever before.'
DR. ROSENMAN: In our type of socioeconomic environment,
the environment of the industrialized world, if you wan
"° to achieve more and you have more obstructions, traffic,~
'" persons, things, what do you do today? Well, either yo.~.Z
become more frustrated or you hurry..
• DR. SELl"E: You use up energy to resist an infection, to
fight intoxication. You use up energy to think. And
the more energy you use, the more you are under stress.
D_~R. RATCLIFFE: What we are doing to ourselves is what's
killing us off at an unnecessarily early time. "
.NARRATOR: ..In this--m&mwelo~--mech~n~e~age~4~, .
u~.su~t of te~hnml/,gical-.adVancemen~T~h~O~~s~it
CONFIDENTIAL
MINNESOTA TOBACCO UT GATION TIMN 0077926

---

• " .. .... CONFIDENTIAL. '
.~ on to pay somewhere~e~.~e~~s whatf ~-~--~-- seems like progress'
'i create new pro s to be s~~a~o_ur very
For the next few minutes, we will be examining our stress-
ful souiety: what it's doing to us, ~nd ~he. :kmpact of our
t~tal behavior on our health. Specifically, we will be
. .
looking into one of the more controversial a~pects of
modern life: tobacco and its use, p.articularly in
c-gare--esl uu ~"
--"
""
/ ,, -
To help us gain new perspective on the question of
1
smoking ~nd health, w~ will hear from world-r~n.owned
.
&..scientists and experts.
,.~v~s~ ~oI~ o~ ~;~,~c~,~s: { '. .~"
• ,,,~.....~ K. Alexander Brownlee, M. A., Retired .~~ate Professor~
of Statistics, University of" Chicago
.-.
Rune Cederlof, Ph.D., Associate Professor of Environ-
mental Hygiene, National Institute of Public Health,
Stockholm ~ ;)
Arthur Furst, Ph.D., Director, Institute of Chemical
Biology, University of San Francisco ~0 ~3
TIMN 0077928
CONFIDENTIAL ~"
00213~6
MINNESOTA TOBACCO LITIGATION
~v~I,EG~ ~ CONFIDENTIAL

• ' CONFIDENIi :.
E. Cuyler Hammond, Sc.D., Vice President for ~idemiology
and Statistics, American Cancer Society-'~-'{~,~
Hiram T. Langston, M. D., Thoracic Surgeon and Professor
of Surgery, University of Illinois Colleg_~.of Medicine
Edwin R. Levine, M. D., Director, Department of Inhala-
tion Therapy and the Cardiopulmonary Laboratory; Edge-
water Hospital, Chicago , ~%~ "11. ~, ..
Hans Meier, D.V.M., Senior Staff Scientist, Jackson
Laboratory, Bar Harbor, Maine, and member of "Scientific
Adviso~ Board, Council for Tobacco Research ~ '
William B. Ober, M. D., Clinical Professor of Pathology,
Herbert L. Ratcliffe, Sc.D., Pathologist ~d Professor
~eritus, University of Pe~sylv~ia ~,~
Ray Rosenman, M. D., Associate Director, Harold Brunn
Institute of Cardiovascular Research, San Francisco
Carl C. Seltzer, Ph.D., Senior Research Associate in
Biological Anthropology, Harvard University School of
Publi~ Health </,~, ~'~. ~, ?
TIMN 0077929
CONFn~E~CrtAL "V 0021377
MIIN1NESOTA TOBACCO LITIGATION
~EG~D AND CONRDENTIAL
ProCeed as requiredl~y~ ~Court's March 7, 1998 Or,~er ;11
State of Minnesota, ._: ~]. v. Philip Morris, et al
Court File No.: C1-94-8565

M~OTA TOBACCO LITIGATION . • . -." ,~u..
H~s Selye, M. D., Director, Institute of Experimental
Medicine ~d Surge~, University of.Montreal)
~e hectic lives we lead today is considered by some ~o
be a direct contributing factor to the t~e of disease
one wall die from.
Dr. Hans Selye is a world-respected expert on the stress
• - of life. By-stress, he means the rate of all wear and
tear oausedby life.
DR. SELYE: There are certain responses--disease responses--
which are not due actually to what we'think is the
disease-p~oducing agent, but to our body's defective
response to it. Cardiac disease, hypertension, cer-
• tai~ types of so-called alleygic disease. Inflammation..)"
L~ sive reactions of our body against insults which do not
re~ire such ~ excessive response. ~ ~l~z&aca~ - ~

• .: ,~,~,~ ~ ~ . philip
~ . •~ ,~anesot , 565 : -5-
• .... l • -.. CONFIDENTIAL.
~ D l LTZE.R: It's very serious, the single highest--------7
V
~ ategory of disease. S xty percent of the men who die/
~n, this country die frol heart disease. " .
/
NAR TOR: Naturally, animals are not the same a/human
~ " d cannot necessl~rily be compared
expJlmentally..
/
But the~ have been--thrDughout the histo y~f medical,
research-~nstances wher, the results of./ nimal experil
ments and ~imal .observation have hel~ ~ us .to understand
'" ~RRATOR: ~. Heart is an expert, on. animal
' '
r.esponseto stressfu~ ..For example, in on~ •
experiment he radical: a flock of chickens,
which normally consists ~ rooster and a great many
hens. He divided t~e into different sized
groups with a ~n acl
two roosters to every
hen. The resu~
~egan killing off the
males. The hearts were
badly damaged." The
conclusions
/
.DR. Animals p~laced in
)ns where they
are ~le to carry out aI behavior ~
is .
stic of the spe~cies--where their
is
be expected to develop heart
d to die of heart disease. And this we can
to the primates, includin the gorillas, which are,
think, about as close to man as any other animal is. |
TIMN 0077931
CONFIDENTIAL -/-
00~13~9
MINNESOTA TOBACCO LITIGATION

~,.~: .~s~;~,Court File ~ No.:ai' V.c1.94_8565 Philip Morns, e~
,~. ~m~n---c-i-tu ati :n ~-
~ we ~r~ ho~m~in much
" ~ ....
~TOR: The second ~=--~ ~7~ ~ .I" ~s c~cer. A
S~ply stated, c~cer is. a m~i~t gro~h somewhere in
~e body which tends to spread~t t~.z often ferret i& --'~
~.--~~ith._the. spreading., of..tha~-. ~no~i~~cer,
laterally, c~ attack ~y p~t or el~t of the ~atomy.
~ere ~e c~cers in the l~ph syst~, blood c~cer,
~_~ne c~cer, brain c~cer, skin c~cer.
. , . . ,
~_~ ~. FU~Tx ~en does a group of tissues become ~no~al~
~ So far we haven' t the slightest ide~.
does
a
nodal
./ cell which grows the no~ way, divides the no~ way,
why does a single cell of this suddenly ch~ge into a
c~cer cell2
• " T~N 0077932
COffeE.TIlL .
~~SOTA TOBACCO LITIGATION ( 0021380

read, o~~$nq--as so m~y peo~t~
" "~~ ~o=t. ~.he cause of cancer, I think we should spe~ of
NA~TOR: NeW discoveries suggesting vi~ses as possible
causes of some t~es of c~cers have ~cited the scientific
'
~ ~ At the Jaukson L~orato~ ~n Bar Har~r,
Maine, Dr. H~s Meier ~d his collea~es ~ mice
different kinds of c~cers.
DR. MEIER: rinses do cause cancer. We are working on
g~es which control certain cellul~ compo~ds which we
c~l r~onucleic acid. It's like a vies by physic~-
ch~ical ~d biologic~ b~avior. It is unl~e the
co,on t~e of vies in that it is not tr~smitted
horizont~ly from individual to individual, but it is
the product of each individual ' s inherit~ce.
NA~TOR: Others have noted ~ app~ent g~etic suscepti-
bility to c~cers. For ~ple, ~ ~ex~der Br~lee,
CONFIDENTIAL
MINNESOTA TOBACCO LITIGATION TIMN 0077933

PRIVILEGED AND CONFID~AI+
" - ~ u. • : ~:~.,+:-~.~ Court's March 7,1998 Oni~
• ' ~ + ~J~ ~v~_..::, :c.- ~,,. :~ al. v. Philip Morris, et al,
,.' ', Court File No.: C1-94-8565 -8-
.... iFIDENTIAL
-~ --- ~ ~-~1~l-~--dC ;;3a associate
prb£essor" o£ st~t±sties ~t the Un£versity o~ Chicago--
PROF. BROWNLEE: There have been studies for ethnic
groups in the United States, ethnic groups moving in
as a body from various European countries. It is found
that the lung.cancer rate for these ethnic groups
corresponds more closely with their original European
compatriots than with the general U. S. population.
This strongly suggests a •strong genetic component of
this dis6ase.
I
In recent years, no
more ~estions, more controversy, th~ c~cer of the
.--- "+ ...... ~ "~ ~+
int~.:ifi~
lung. ~I~ ~wo~,,~ :f _..iz
....... i ~th " .........
"
app~t statistic~ association between smoking
T ~021382.
CO E IaL
•

produce t~ese statistics was cc~ri~e~
ccm~ G~,~OC ''"'i .............. u_n_nzrc __ - the ~eric~
C~cer Society. ~ey selected more th~ a million men
women ~=~- ~],~ -.-~.. ~r no to fill out ~estionnaires ~out
their health, past illnesses, smoking ~d other aspects
of living.
The material was then turned over to ~. C.uyler Hammond,
the chief statistician for the American Cancer Society~
DR. HAMMOND: ...And I had our compute~ do a matching
prob.lem. I, for this analysis, took the records of
men who'd never smoked re.gularly an~ the records of men
who'd smoked 20 or more cigarettes a day.
Then I had the computer take the first man who'd never
smoked regularly and look through all the files for a
smoker who was as much like him as possible. "~_ h ~ ' ~
~£~.-~
TI N 7793S
CON ENTI 0031383
MI OTA TOBACCO LITIGA ON

m_en ~na-~.~mok~ z-,--~noth~r - ~-n~..~ ker;, --wh~er ~ -&l.ike--~.-~k--
,.Ozl-a~l,-thes~, other, thi~gs~ ~.~ . ,..,. .................................... ,
At the end of 44 months, there were 600 ~d some deaths
in the nonsmokers ~d 1300 ~d some deaths in the smokers.
~out 15 or 20 times as m~y smokers as nonsmokers had
died of l~g c~cer.
. [m~[ highly respected m~ers.of the scientific co~un~
~rom the Ve~ ok-v~gorous exception to the
statistic~ methods ~d how the n~ers were use~.
For.
~ were from ~! .cz~n_i~~ ~, .... ~ '.~Z"~ ~-l ....
" ...... " ' -,
Z~!~ ~ ~tazt~n--:~--- fc~ the ~dustrial northeast
~d midwest ~d virtually none from the ~tain states.
~R. 0BERt L~g c~cer is predo~n~tly.a disease of
people who live in large cities or in industrial ar~as,
whereas people who live in ~ral co,unities have a much
lower incidence of lung c~cer.
CO~ENTIAL
• . ~00a~S4
M~OTA TOBACCO LI~GATION
TI N 0077936

.PR.OF. BROWNLEE: The Hammond Survey for the American
Can.cer Society suffers from the defect there was no/ a
/
properly defined population. So we just don't
kn~w what
the population was.
/
• ..
/
|
/
DR. EYSENCK: The ordinary statistical met s that have
been use~. are really quite worthless. The/y don' t prove
|
anything a~ all, except that there may/.
may not be a
/
relationshipJ _ ,
/
., DR. ,OBER: The actual number of cases of lung cancer--
. although recognizable and significant--is
not
terribly,.
~/~ / t.erribly.large, ,whereas the ~umber. of. people who smoke
/ ~lgarettes is extremely larg~_. And any theory which
'(~~~"~'. ' explains why A causes B also has to "explain why A does ~ ~¢~
not'cause B in the people in whom it does not occur.
• And this is the one thing which these people have not ~
~ explained. It's an incomplete theory.
.N RRATC,~. ~ ~7~ ,,=~ -expia~neu.,wny une ~'~rted death.
rate from all~ypes of respiratory, diseases has steadily.
declined sin/e 1900, while cigarette consumption has
d/n " ""
increase almost directly opposite~ proportions.
/ ' " "' "
ny.~. low.nce is made by proponents of the smoking-lung
~for other possible causes of cancer'of~t~h~
CO~ENTIAL
• MINNESOTA TOBACCO LITIGATION ~r'00213~

.. . PRIVILEGED AND CONHDE~
" - i."~iced as required by t1~ ~ourt's March 7,1998 Order
State of Minnesota, et al. v. Philip Morris, et aL
- 12- ~ Corot File No.: C1-94-856~
,DR. LEVINE: There are substances in the air in every
city in the United States--and I suspect in every city
in the world-=which are.known to produce cancer.
~ Herbert ~ Rateliff~has noted a si~ifie~t inergase
in the fre~en~ of l~g c~cer ~ water fowl--especially
in two species of ducks at the Philadelphia zoo--located
in a t~ic~l city air pollution ~ea.
s s~le ~at they were ingesting materxal
~at has be~ deposited in this mud ~d that ~cretion by
way of ~e lungs is a possible ~it of the carcinog~s
~at are t~en in through the mouth.
CO~ENT~: T~ 0077938
M~SOTA TOBACCO LITIGATION

The other possibility is that they are inhaling it. If
SO~ they seem to be peculiarly susceptible to inhalation
Of carcinogens.
Siberi~ tiger died in the Philadelphia zoo. Cause of
death as dete~ned by autopsy: c~cer of ~e lung.
Others point out additional factors statistically
associated with the disease. ~ere's the matter of a.
marked differ~ce of the rate by sex.
~G~TON: ~is disease is a male disease. It is
DR.
six or eight to one in favor of m~es. Wom~ do get the
disease, it is t~e. But £hey do not get it wi~ the
s~e fre~ency as the m~e. ~~ ....
=~ain~-rather constant. It has .not increase, ~d
~~n~.~s-.t~ng ~out the m~ked ri~e in th~ incid~ce-
,. M~SOTA TOBACCO LITIGATION

'"-, ~ D-~dT,'.
. ,~, .'d'-li :~--I~,|
~e same " w~agent,
that one has ass~ed--~ote--~epid~ic ....
NAR~TOR:. ~other ch~lenge has be~ base,on how you
measure what really caused a person's dea~. Dia~ostic
'
cap~ility wi~ respect to c~cer of th/l~g is a re-
latively recent develo~m~t.
" y . " g~ools .now for diagn "
as to what ~e prev~ce~f l~g c~cer was at ~at.
.
p~cul~ t~e.
. . •
. / .. ..•
. . .
~TOR" Most mot ity stat~ti~ in ~e cig~ette'
. . ~ity ~tat~ti~ in ~e cig~
DR. OBER: / dea~ ce~ficates ~otoriously
~less akrerson ~as ~een
ac~rate./~ ~e first place, ~ffi~l~e~ sure
antopsi~, somet~es it' s v~
whiP, died of. ~ " ~ ~"
~TOR: ~at ~st~es ~ght occ~ ~ d~a~o~s "of
/g c~cer based only £n death c~ifica~es?. ~
CO~E~I~
~~so~ ~o.~cco u~,6~,o~ T~N ee7794e

, ~d m~y c~cers arising in other parts of ~ body ~el
I filtered ou~ ~d ~ deposits--~hieh are ~alled ,
metastatic c~cer--in the lung.
~at are diagnosed as ~ c~c~r without ~utopsy may
not be lung c~cer ~all, but c~cers in o~er org~s..
.~R. OBER: ~n I read ~ article in the medical litera~re
whlch i~..~ased upon death certifZcates I stop readifig it'~
~ bec ere's no point in my wasting my t~e. ~"~ve
,.,I/er thlngStion, to read which, are based on. . a fi=er founa~-;
~R~TOR: 'Though th: mo~t :t::klng associatlu**
One =zaz_~:z=:.:i.. -- corona~ illness.
~ we fo~d that there were2more th~ twice as m~y s~kers
~at died of heart disease as nonsmokers.
" N~TOR:/ M~y ~dversaries of smoking support~
'~ view. Oehers ~e not satisfied with ~his s~ple
conclusion. ' 007794
CO~E~L ~ ,
M~SOTA TOBACCO LITIGATION

~: Few people ~e~i~e that actually the.j..~
,~tatistic~l risk so-called which has been given~it by
"~~lic He~th Se~ice of heart disease o~'~i~okers t~
States, J~p~ ~d Switzerl~d--~h ~rom arteriosclerosi~
~t~ 1955~~- ~hile it was rising by more~ 30 percen~
~ such/. "~ow-cig~ette-cons~ption. . . . coun tries~weden,. "~ "
~ ~s we've seen w~ ~espec~ ~o lun~ ~ce~,~e
of statistics ~ l~ted.
~e . S~geon General's repo .... had a& much
specific~ly stated that statistical methods c~ not
est~lish proof of a causal relationship in ~ associa-
tion.
Yet ~ere were some whosy n~tural desire to fi~
~. ~% .... ~t~j' z-1~z.- 1 Aii~h~zrt fizt--- ~ay have
led ~ to disreg~d ~is caution.
" el aft ....
_~9"~ ~~d .ee~.. hea=%- dlseas~.
. - TI N 0077942
CONFmENTIAL ~ 00Z~S0
M~SOTA TOBACCO LI~GATION

/~ ............................ Natlonal Heart
and Lung Institute points out that we've learned so much ~bout
how to treat heart ailments that we overlook how little we "know
about their causes. "We tend to obscure our ignorance, " t~e
Institute says, "by making it seem that a problem has been so'ived
when it has, in fact, Only been half-solved."
FFdV~EGED AND CONFIDENT!~.y.
~ as required by the Cohort's ~',.~,~ ~ .
State of Minnesota, et al. v. Philip
Court File No.: C1-94-8565
CONFIDENTIAL
MINNESOTA TOBACCO LITIGATION
TIMN 0077943

~igarette. smoki~and corona~isease,- I. think we~ . .
-1969 -- The~eric~'Hea~ ~s
earch director
. ',told Congress~/ "Let's be sure we ~derst~.the. Heart
~Associati'o/~osition: We do not .say that we ~ave
• . .
. ,data says. cigarett~ smoking causes coron~
/
~ui~.~).. ', ..... -.
~ ... ~.~uk'-::~? What avenues 'of meaningful research should be
explored if the answers aren't all in? ,.
Many authorities feel that more attention should be
given to the smoker rather .than the smoke.
What kind of people smoke and why? Do they
differ from
those who don't smoke?
DR. SELTZER: Smokers tend to be more agressive, outgo£ng,
- extroverted people--hard driving, full. of tension. They
tend to marry more often, divorce more often, move their
houses more often, change their occupations more often
~han do nonsmokers. TIN~N 0077944
CONFIDENTIAL .'~-00~139Z
MINN~OTA TOBACCO LITIGATION
?RI~LEGED
_Cou~ File No.: C1-9@BF6~

DR. SELYE: The human being smokes only because he likes
to smoke. Nobody smokes because he .h,as, to smoke. "J~L~d
,~-~-~ emmet.-.-~ ~o~ ~o smoke. Su £~ l-~i~,, i-~-i~ ~ d~~
~:to~l oth~~~~~ .... ~---,~ ..... , .... ~' .~,'
DR. CEDE~OF: Say that you are a certain t~e of person
~d you like to..s~ke. You may also then be:.more
apt to start driving or more apt to h~ve a stressing
job or something like that. .
NAR T~R: ~or the past several years, Dr. R~e Cederlof
of Sweden's National Institute of P~lic Heal~ has
studied the effect of smoking ~d
.....
-- . ~ , ~
%
~. C~E~OF:~ Ye~ ~w. we did ask for a lot of other
~~a~-~.~.~~ ex~ ~a for.. d~e,~.
smok~r,,.i~,monozyg~ca=that is id~tical-~twi~s ~i1~-"~
" ... .
~would. ~"up what we have found here in such a ~ay ~at
._S_~k~ng.does not se~ to cause he~t disease, that is the'
~d_.~-heart disease we are studying--u6rona~ heart - ~.'
CONFmENTI 00 13 3
M~SOTA TOBACCO LITIGATION
TIMN 0077945

........ There seem to be other ex-
planntions for it, ~nd we are trying of course also to
see what other explanations are there.
NARRATOR: Dr. Ray Rosenman .is director, of what is
called the WestErn Collaborative Group Study. He has
found a striking association between behavior types and
heart disease.
,
-~an--be - di-~i~--i~to-beh a%~iom- ~y~ e.~A- -an ~-,~avi~ z~Typ~~ B-. ....
DR. ROSENMAN: The behavior pattern that we're studying
is concerned first with personality attrib~tes--such as
aggressiveness, ambition, drive--the drive to achieve,
the drive to get things done--competitiveness.
Type A individuals are simply individuals who exhibit
most or all of these different personality facets to an
erahanced degree - an exaggerated degree.
In general, the Type B individual is much more relaxed,
much more easy-going, ~sn;.t constantly-pay attention
Co .the clock.S_eel_-_' ~ ~.nv~~- .~...- ~- ~a ~_-~ .t--'-~.~--~r~_s-~-
.E~r£tc-doesn~-ten-d"~o ~"to "bed"at ~ight or ~ke. ~/p -i-n. .........
~.~e._m.o__r..~i~g planning.-~-their day ~, ,squeeze-more ou~f
exery minhte. .................
• TI N 8.77946
CONFIDENTIAL 7- 0021894
MINNESOTA TOBACCO LITIGATION

Drl Rosenman and his associates concluded:
DR. ROSENMAN: Men with the Type Acoronarybehavior patternmen
o Ymoro
with the T~e B behavior pattern.
. .
~ all .,,a. i~
-~----~ ~- -' u pereen~ were T~~d ~=~-~.~
~ght ve~ well expect, the ~ehavior patte~ is related
to the smoking h~it.
~TOR: ~e Surgeon General's report relat~ a higher
dea~ rate to smokers th~ nonsmokers in more th~ 20
different ~eas--including accid~ts ~d suicide. Let's.
look at just one more. ~phys~a.
Simply stated, emphysema occurs when the lungs lose their
elasticity so that it becomes progressively more difficult
to breathe. Opinions vary about any role played by
cigarette smoking.
•. 7"0021395
CO FtOENTIAL TIMN 0077947
MINNESOTA TOBACCO LITIGATION

DR. HAMMOND: Emphysema in the United States is caused
primarily by smoking and it's a major cause of disability.
LEVINE: Wail, my feeling is that there is no eQidence
that cigarette smoklng has a dlrect causal relatlonshlp
~e origin of ~phys~a is shrouded in a great deal of
~ste~, ~d ~e only method ~at has been successful to
~e blood
vessels which are nutrient to ~e l~g.
~TOR: A recent gove~t repo~ su~ed it up by
obse~g "that "s~ce there are no claret-cut leads as ta
~ cause or causes of ~phys~a, no ~ick solution to
~e probl~ c~ be ~ticipated.~~y complex ~est~o~s
r~n to be ~ered. "
TIMN 0077948
CONFIDENTIAL

D,R. AVIADO-" (page 6, new Aust. film) I have examined all the articles rela
ing to this subject, reviewed each one carefully, and I have come ~o the ~
conclusion that there is no evidence at all that a healthy nonsmoker suffer
from being exposed to cigarette sm.oke~
rch
PRIVILEGED AND CONFIDENTIAL
Fr~uced as required by the Court's March 7,1998 Order in
State of Minnesota, et al. v. Philip Morris, et al.
Com~ File No.: C1-94-8565
CONFIDENTIAL
MINNESOTA TOBACCO LITIGATION
TIMN 0077949

DR. S TZER: i think where we stand now--the hes
say--is we d6 not know whether or not there is.,a causal
.
relationship between smoking, and heart .d~s~ase. Neither
does the Public' Health Service know. /~"do I
_.-. ,.
I /- '
.
/ .. -,
DR. LEV~NE: There a~'large n~ers o~ ~s, who hav~ some
"' ~a~kgzouna in th~s field, who do not ~eli~v~',t~e
.
~A~OR: ~ou~ gene=~l statistical associations o~
/~[ OBER: I th~ we have a great deal to le~. ~d I
/~ far too m~y people have ~s~ed to a pr~ature.
~jud~t based upon ve~ .inade~a~e evid~ce, chiefly .
kbecause of ~e. tr~dous ~otion~ need to oversimpli~
'~ ~d to m~e ~ings easy ~d palat~le for the public, for
~dic~ students as well as for legislators.
, . / ~. • .,. . _
• .
: ~:.'~li~te lun~ c~ncer~ c~rdio vascular dis~se~ ~nd so on.
' ~'~'::':" ' " ~00~1398
CO~ENTIAL TIMN 00779 0
M~SOTA TOBACCO LITIGATION

w " ' expect a speedy breakthrough here --say
~~ ,._r_ hre~throuqh, T .
od ide ~.~~ ~.~
hi
k..~ . - .... ~ ~-~',~--~, ,~ ~ ~ ~ ~ ~*~!~'' - - "~ "~ ~___--" ~
_
~w~,~ ~,~ ~'~ ~&;~ As our society accelerates at ~
~ncreasingly ffaster pace ~d grows more complicated, we
~ ~
e fforced to seek ,t~e ~swers, based not on statistic~
coincidence but on me~ng~l rese~ch into causes%
~s mor~~s~vi~St- ~-~v~t~eth ye~, ~e"~"
~u~h~ ~e-f~hat~o~ factors-prod~..~.-~&~e~e~,-~- ,
~f~yin@ ~i~ dinner-people :. .in. d~fer~t behav~q=~-~
~S~ ~on~. men-a~ ag~nst womb, . differe~t_e~!~ ........... ~,
~~"~Dng'~pl~"w~th diffe£~nt ~iet~--h~i.ts~_ ;,. ..,....~
CONFIDENTIAL
MINNESOTA TOBACCO LITIGATION
TIMN 0077951

• PRIVILEGED AND CONFIDENTIAL
,._ - -... l~++~uced~ StateaS requiredby the Court's=_ March 7,1998
Order
, . -. of Minnesota,.et al..v. Philip Morris, et
.. - Court File No.: C1-94-8565
NARRATOR: The tobacco indust~ ~s conceded ~out the
~plica£ions for its products. Xt ~elieves info~ed
, discussion is essential to the p~lic interest. Xts ~c
.sc~tif~c research ~ in the, ~ea oZ smoking ~d .
~ ~
~h~ng we need is a good idea. We need more good ideas
~d we need more go~ ~ality research.
CONFIDENTIAL
MINNESOTA TOBACCO LITIGATION - +
TIMN 0077952
~ 00Z~400
