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Holtzm~~+~ Gallup s letter of 6/3/71 I0: ....... ' PHILIP MORRIS INCORPORATED ':'~" , ~:,..~!.:.~!.:. ! .- • ;, INTER-OFFICE CORRESPONDENCE "1' " •' 100 Park Avenue, New'York, N.Y. 10017 ~;.,..~,,~ ",'.,,'. ~,.,, , ~'.-. ..... :" 'Date: June"7, 1971 . ~'., ~ ,. • .' , ~ ',~. ,,,,~ : ':. ~.y.::.u.~ ~ .... .'.;~ : ;. ';: : .:~ }.;: . . ..., ~tatement f,Forsome dfseases,:e~g. lung cancer and .bronchitis, the excess among smokers is so marked ~'~ so '~ons.fsten.tly found that cigarette smoking is considered c~usal szgnlficance" does"not referr to results or a " ~pre~ise~df twin studies; it referrs to references 4: ~}',I).The Surgeon General's Report 2)-4) The Health ~onse~ ..... ~ Smoking, 1967,.1968, 1969• i!~.~i:.~"-:,:~'-.:'i."i':?!~'..", ~,. :. thors referr to "an unwillingness to accept • causal role for cigarette smoking in relation to these 'dlseases"(i.e., cardiovascular diseases), they are ingto the stand taken by PHS: in the 1969 Health .:.:c::..,,.._ uences "of Smoking they list smoking as a risk factor . than a causative factor ,'.,-, ........... .... e I!.. + : - . ' ,_.. ~.:., ..:.. ..,~,~, ~...,~.,,...:. ,., ..~...,. ~ ... .. ~ . . " . i~" '.. ~':' ~' ~ ..,' .. . ... "., . , ii..,ii:'~ In covering the need for studies in different popul~tions . subgroups the authors emphasize the lack of such studies _. ~,,w~t regard.to..CVD. There are no direc~ statements that ..... - type of reseach has been sufficiently covered and exhausted pulmonary diseases. • To the contrary, on page 22, the authors esc~ib~i,."the potential of twin registries for investigating relation of smoking and other variables to health status ~nd particularly to CHD and chronic respiratory disease.. " ~.': ~.- -.. -.. - :..::..~.- -.?,+:.-. ~ ......... - ~_ . ~..'n looking at these "soft points" in the Puerto Rican ~onference report one must recall these two items" " ~ ~:,~ .,.~-..~ ., .... ~ . ..~...'.,i:~--.~._.." :.:~L.. .. ~ .. .. " ::. . :~.,.~....,_ . ..-- ) : .Sel.t.zer s. open~n_g remarks in h~s recent letter : .......... : .....:-to tne e.dmtor of the New England J of Medmcmne .......... ;,~ ~. ~ .. -, .:..! ...,, "..~"?.'..-.,..-------- .... • . - ~,- ' ....... :,.-:....-:.~: .-..-,:-..-.~ ~f,..,~,.,..,:--:..,.,:.cfted. the anti-s~ok~_n~ literature• • It has been s ested ,., ...... .- .... ..-..-,.v~..~,- .--:-~., ..................... ugg. .:~... "":,/~,-'--.~-i.i.'"-'..!.:i,:!~::.:::i,%hat ~e ~ecular rise in death rate.from he,art disease ,:". .. ::~il.... .. ...",,.:i-~ • '.i-:.~i.i~i;?:.. ~_ara!~.-~.is~._~~~r ~ncrease_ in cmgarette, consumption. .,~ ,'...~o ..'..~..:.:.." ' . . '..-.~.- . ,'..'~;.. :' ~,. , . . ... .... • '2) Hickey's remarks on S&H in his recent chapter : " fn " -" "Th • ere are no ~.~ major disagreements over whether or not correlations , .. .. exist between smoking and lung cancer mortality. - -The associations do in fact exist; but uniformat~.y -.-,~-..- • " ..... '~:- - . - :.,i'. of opinion does not exist regardi.ng the interpretation . . of the statistical findings." Th~s applies to the whole field of smoking and chronic dmseases. .. ,,.~-~,..::.-- " ~ " . • . ~. ...... . ...... t'. :)- . . " . ~:.. - - . :" " -..' -. , . . • ~-~'. • ~.~.:... ...... ...~..-..-::.~ ~..,:'~.,... -.-. :..: .. ; , . . .. ~..-.~.--~..~: . . : .... ... -... : .~.. . . ~ ~, "~i~~-.':. " ~:' :":'-'~:-": • .... .'::-',~~-',~:~':.'.-~.," '-~--. .- - . ::.:':~...~:.-~!:~:: ',-"- : - .... .. :~:~.: ,-i ..... ?.,.+r~:~:;.+~,r:,~,,-+~,.. " .. - • +...+,,+...' ,+..-.,-+~: :- ~.. ; -+.:'...,~.:.,+. .. ._':.--.:::.+, .

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