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.ihook,- Hardy, Oft1~.~a~, Mitc~ell
for Joseph F. Cul!man 3rd,
• of -the...Board,.: Philip Morris
.......:_,, . :igaret~e idustry re.cognizes- its -respons
~'-~ '.o the Ame~.ican ~eop!e. :.It is~nxious to seek the a~s~!~
• .- q~estion"Of .whether-cigarettes are in fact the causei~..
! .h~mn..~sease~ -~It is unfortunate ~hat emotional propa
~nd~ 'against ::digaret~es has been perraitted to .~upp~ess).
~cientific ~.:in~l~iry and :proof. ----As a result , ".instead of
the~search fo~-~he._true causes of some dise~se~
to be statistically associated with c~garette smokzn
~earchers have accepted ~.~thout investigation ~he contention
;hat cigarettesare the principal cause and, therefore,-
.~ ::Cdeclined ~o devote their valuable time to research dir~e~fid .
needed for
--."~:~-]).".:~-;~:~.~)at dete~ining the causes of the~e diseases.- Funds
~.~i?,~]~:~~?.~'i~?~important work have been diverted .to ot~er uses.
,i..'_.-'L~ ..... -1~..,':~i~- -. ;-..- .Whe truth of ~he matte~ ~s th~s...~.,~:~.~:~
•. ...... ~.E~... :"- ~.-.-~:..-/~-A host of factors ~s under suspicion as con-
-"-"-'~"- . ~-- tributin~ to thos~ diseases which appear
to
be
- ~. ... : .,-.-..--~.~-:.-~tat~st~cally associated .w~th c~.garette smo
-~:~-~ " ... -, ~-.. ~.. .-." . "~ ..,~ ~ng. ~hese include air p011utauts, hereditary
" ~_" .~l ,.
~
-
.... ~- . and constitutio~l factors previou~ lung damage;
-": _- --.- ., ~'~ ". and others. ' -~. ~ -~ 1: ' ' " : ... , -:,~: ~'~~'~-:~.".~".
.,
.... " .~! . . . =.. , - ..... . .. - .,,...-. ...... . ,( " .... ~" ' -.-""
~'"
..._ .. . . susp c oa on c gare te
allegedly show an.association between cila~ette
• .~,::~:~.C~.~.':~--..~"~::.~.-~~."~"..~:~:.~.~:"."~smoRi~g and c.er~a~n' diseases,.- Every one
of .~hese
. :~.. .... ., studies is subject to criticis~ On a purely
.... " ....... '-"=-~ .... '"D:"# ])-- -..~ i. methods employed and inferences drawa from the
statistics. ~ .~."~ --. ' ~- " . ~" " ~- ".~-:"---
;"0~[~.~~:-
.,'..., ',-~-.~o',L-, .... -..:~, ._.... ... ........ .:._...
-~.-.-,~. :...~-2~-%.'-.- ~? :.~- "Even valid statistical associat~.o~s can b~ly
....• . -~;"~':"...: .... .... "/:". point" the finger of suspicion --
.... • ~"-~- - '-" .. prove cause and effect.
-Cause and effect can only be proved by
~ g th~ [ngredien~ bY .~.~ta~cn -~ an~ the meehan~smb~
" "-- ~- ~ ~e o~ ~h~ alle~ed ha~m~uJ effects of
...- .... . ~&; ~ ~-~
~ -- ~ _ " _ .
.- ~
. - .... ... " e~arette smo~<mng, tremendous researcn
.... • -.- '. hav~ never b~en able to demonstraue emther =ny ,~.~
" • --. ~.. " •~ A'ent or any mechan~s~ n=~dad to show-that.~
..,. , ......... . ..... _ .,,... ...., • .. . .
., .. , .....

Page 2: 1002617284
: .-.. .. £heory that. cigarettes cause disease, i'llFor exam
Human-£ype"lung"canc4r haS':never been produei
the lungs of experimental animals, by inhalation
.....• -~-.,:""~",,,,..: ..~.. ,: cigarette smoke, but has been produced
experi~.
lly by inhalation of other suspected a
I countries ~,ith lower per capita,con~
cigarettes than the United States have highe'
" Lity. rates from. lung cancer than doesthe
Stat~s "- -:- • "
10% to 2'0%.of lung cancer in men oceu'rs mn non-
~ and is indistinguishable from a .similar~'cancer:
" 7The age~of peak incidence of lung cancer
, .~ :-~...;..[>-~:: ........ ~..:>?:a~out sixty years, regardless of whether or
, - .~"~'.~- . - .the n~ber of men smoking, the gap between male
. ~"-." .? .... :~.,~2:~ .<~.~.~.~female lung cancer death rate has actually widened
". - ~:~-~"~ ~,:"$-::"- " ~ ~ There are now about six cases of male lung cancer
-: :~ , -.~T"-:"!~:-~~.(~~.."~-:~ .~-: ~ to each case of female lung cancerS while in 1930
• - -..~". ...... ~- -- .- .... ,-there was little difference.
...-..-:~...,<.~.,~.-.-~.:....~. ~~ Suspected ingredients in cigarette smoke.
..... , ....... -~<.. .- Studie9 have sho~,m a greater frequency of heart
.; --:..--- .~:.~ ':~:;,--~-..:.'~.~ no difference-between the smoking t~,ins and the non~-.,
. . ...- .. :~>~.:~k ~ :~.~..?~<7-~. - Cigarette .smoking did.not exist when chronic ....
. ,~-~~-.~.~..-.."~. j" ~:.~~.-~~- ." ~ronchit~.s and emphysema were first recognized.
.- _.:.-,...~ :.......-.. /' . Both diseases ocaur in non-smo!<ers, and the cadse
......,~.:. " .. ':,--..~ of emphysema .is adnittedly not actually, knob,m,.
.-...:. ~ - even by n~any of t~ose who publicly blame cigarette~.:
. . - Many of those-who publicly c0~demn ciRarette.s
" " " ' " con~e,d,e tha,t ~here is an, ab~en,ce of proof ~o sho~.~
". - " .. " that cigarette s~oking causes h=art ~iseas=
..... . .....
. • . ~,
. .. .- .... . The Surgeo~ ~en._~al s Advxsorv Con~mxttee rn~~
.- . - ~ that n_co , ~ o.,~ not r D
.
~m ortan~ health ~azar~ et
• ... .... <:-. .... " .~... P , y the publ~c has been

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..... .
. -:?: invest~ga~ozs who dis~-.,oree wish the theory that smo,<ing: c~uses' . .disease...:-The~e
have been either ignored or belittled.