Bliley PM
Re: Franklin Institute
Abstract
Discusses industry-funded research claiming to isolate an allergen ("glycoprotein" or "TGP") from tobacco smoke. Remarks that Becker's TGP "included a substantial artifact." Relates that Stedman and Becker believe that it should be tested using Becker's original assays for biological activity. Advocates additional funding to generate "25 milligrams of artifact" for researchers at Tulane and other institutions for biological testing.
Fields
- Type
- Memorandum
- Author
- Finnegan, Timothy M. (Attorney, Jacob & Medinger)Worked defending producers of smokeless tobacco (snuff).
- Recipient
- Ahrensfeld, Thomas F. (PM General Counsel & Sr. VP, TI Executive Committee)TI Executive committee
- Crohn, M.H.
- Henson, A.American, General
- Pepples, Ernest, J.D. (BW General Counsel and Sr. VP)
- Stevens, Arthur Joseph (LOR Sr. VP '89-95 and TI Communications)Served on Lorillard Board of Directors 1985-92, was Senior Vice President from 1989 to 1995, served as General Counsel for Lorillard '93-95. Served on Tobacco Institute Communications Committee.
- Copied
- Shinn, W.W.
- Brown, J.C.
- Named Person
- Salvaggio
- Shinn, William W. (TI Communications; Shook, Hardy, CTR Attorney)TI Communications Committee and was also a lawyer for CTR. William W. Shinn worked for Shook, Hardy & Bacon.
- Stedman, R.
- Stover, J.R.
- Gardner
- Becker, C.
- Named Organization
- Franklin Institute
- Jacob & Medinger
- Tulane University
- Keyword
- Allergies
- Glycoprotein
- TGP
- Tobacco glycoprotein
- Subject
- Additives
- industry sponsored research
- Smoke
- Tobacco industry scientists
- Toxicology
Document Images
LAW OFFICES
JACOB & MEDINGER
1270:AVENUE OF THEAMERICAS
ROCKEFELLER CENTER
NEW YORK, N.Y. IOO20
EDWIN J. JACOB
FRANK H. MEDINGEF~
TIMOTHY H- FINNEGA, N
September 25, 1979
Memorandum for Messrs. Ahrensfeld
C:rohn
Henson
P'epples
Stevens
Re: Franklin Institute
As you know, we have previously, funded~ research
at the Franklin Institute in connection with Dr. Carl
Becker's claim that h.e has isolated an allergen ("glyco-
protein") from tobacco smoke. This research, wh.ich. ~as
done under the aegis of Dro R~ussell Stedman, i1~dicated
that Dr. Becker's materia:l includ'ed a substantial artifact.
Several months ago we authorized additional re-
search at the Franklin Institute at an estimated cost of
approximately $.19,000. The purpose of this research was
to tie down certain d.eta~is regarding the Becker method and
to characterize chemically the artifact yielded by Dr.
Becket's method. Dr. Stedman and his colleagues: at the
Franklin Institute have completed this phase of the research.
Based upon their preliminary chemical characterization of
the artifact, they believe that it may well he biologically
active and that it should be tested, perhaps in the same
assays used by Dr. Becker, for biological activity. I have
discussed this matter with Dr. Salvaggio at Tulane, as well
as other researchers, and they are eager to obtain some of
this artifact for biological testing.
• Accordingly, I ha.ve solicited from the Franklin
Institute an estimate of ti;e cost of their generating 25
milligrams of artifact for shipment to Dr. Salvagglo and
-2-
other researchers. Frankl~n Institute has estimated this
additional work to cost approximately' $7,700 (see attached
letter of John R. Stover). I have reviewed this matter
with Dr. Stedman, as well as industry scientists, and they
are of the view that the $7,700 that Franklin is seeking
for the generation of this amount of artifact is not un-
reasonable.
I have discussed this matter with Dr. Gardner
and with Bill Shinn and they are of the view that this is
a worthwhile project.
I recommend the approval of this project and
would appreciate your response in this matter.
Best personal regards.
Sincerely,
Timothy No Finnegan
CC:
Hs, Janet C° Brown
William W. Sh.inn, Esq.
