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Bliley PM

Re: Evaluation of Dosimeters for Determination of Certain Constituents of Environmental Cigarette Smoke.

Date: 04 May 1981
Length: 2 pages
1000018661-1000018662
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Abstract

Outlines a research project evaluating different dosimeters and their sensitivity to constituents of environmental cigarette smoke, including carbon monoxide, formaldehyde, and ammonia. States that each researcher working on the project will submit a "fairly comprehensive protocol" for the particular constituents they will be researching. Mentions that the sensitivity, duration of effectiveness, and the effect of smoke on each dosimeter will be determined. Determines the concentration range for each constituent. Same as Bates #1000018646.

Fields

Type
Letter
Author
Senkus, M.
Recipient
Osdene, Thomas Stefan, Ph.D. (Director of Science and Technology, Philip Morris [1986])
Ph.D. in Organic Chemistry. Ten years of research when he started with PM in 1965. Worked in Chemical Research Division of PM 1965-66; Chemical and Biological Research Division 1966-69; Director of Research 1969-1984, also assumed independent position as Director of Research and Extramural Studies during these years; became Director of Science and Technology in 1984, reporting directly to Philip Morris USA Executive VP Mark Serrano. Involved with Center for Indoor Air Research (CIAR) 1988. Attended PM's Operation Downunder Conference in June, 1987. Retired 1993.
Rodgman, A.
Esterle, G.
Jones, T.
Copied
Sirridge, Patrick M. (Attorney, Shook, Hardy and Bacon)
Spears, Alexander White, III (LOR President & CEO)
Associated with CTR, used as an expert in the Mississippi case.
Named Person
Esterle, J. Gilbert (B&W Research, Development & Environ. Dept.)
J. Gilbert (Gil) Esterle worked for B&W in the RD&E Department. He was involved with Cigarette Evaluation & Design and Filter & Cigarette Design in 1964. He was Manager of Research & Development in 1977 and Manager of Chemistry & Development from 1970-76. Esterle was Department Head of Scientific Liaison from 1987-88, Department Head of External Technical Services from 1985-87, and International & External Technical Services Department from 1979-85. He was also Section Leader of Chemistry from 1966-69, and Chairman of ALEPH Foundation in Southampton in 1987-88. Gilbert Esterle was a Brown & Williamson scientist. (PMI's Introduction to Privilege Log and Glossary of Names, Estate of Burl Butler v. PMI, et al, April 19, 1996) Esterle is knowledgeable regarding document destruction. He met with Wells to discuss Deadwood. (Source: Multi-State Deposition Team - Identified Individuals May 9, 1997)
Jones, T.
Osdene, Thomas Stefan, Ph.D. (Director of Science and Technology, Philip Morris [1986])
Ph.D. in Organic Chemistry. Ten years of research when he started with PM in 1965. Worked in Chemical Research Division of PM 1965-66; Chemical and Biological Research Division 1966-69; Director of Research 1969-1984, also assumed independent position as Director of Research and Extramural Studies during these years; became Director of Science and Technology in 1984, reporting directly to Philip Morris USA Executive VP Mark Serrano. Involved with Center for Indoor Air Research (CIAR) 1988. Attended PM's Operation Downunder Conference in June, 1987. Retired 1993.
Rodgman, F. Alan (RJR Fundamental Research Director)
Senior Research Chemist 1954-1965, Head of the Smoke Research Section 1965-1975, Manager of Analytic Research 1975-1976, Director of Research 1976-1980, Director of the Chemical Division 1980-1983, Director of Fundamental R&D 1985-1987.
Keyword
Formaldehyde
Carbon monoxide
Nitrogen dioxide
Nitric Oxide
Hydrogen cyanide
Ammonia
Nicotine
Dosimeter
Smoke study
Environmental cigarette smoke
Thesaurus Term
pollution
industry sponsored research
tobacco industry scientists
#18922 (smoke constituent)

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Page 1: 1000018661
P.~ O. Box 1218 .Winston-Salem, N.C. 27102 May 4, 1981 • Dr. G. Esterle .Mr. T. Jones ~'Dr. T. Osdene Dr. A. Rodgman Re: Evaluation of Dosimeters ~r6r Determination of Certain Constituents of Environmental Cigarette Smoke Gentlemen: In accordance with the discussions on April 27, 1981, I am submitting the protocol that was agreed upon at that meeting along with the Company literature pertaining to your project. It is my understanding that you will review the literature and then submit to me a fairly comprehensive protocol for your project along, with a request for the dosimeters you will require to complete the evaluation. I will purchase the dosimeters and reship them to you. PROTOCOL Purposeof Study To evaluate commercially available dosimeters for the deter- mination of certain constituents of environmental cigarette smoke, namely, formaldehyd;e nitric oxidie and nitrogen dioxide carbon monoxide ammonia hydrogen cyanide nicotine Some Essentials of the Study I. The sensitivity (lower limit) of each dosimeter for a specific constituent will be determined,. 2. The duration of effectiveness of each dosimeter will be determined.
Page 2: 1000018662
- 2 - 3. Effect of smoke on dosimeter performance will be studied, i.e., will the dosimeter function satisfactorily in a smoking environment as effectively as in a non-smoking environment. 4. Reproducibility of data from different dosimeters in a batch and from different batches will be determined. 5. Confirmation of data using independent analytical pro- cedures will be included in the project. 6. Determine reusability of dosimeters where applicable. Assignments The followin,g assignments were ag.reed upon.: Individual - Dr. G. Esterle - Mr. T. Jones- Dr. T. 0sdene - Dr. A. Rodgman - Constituent(s) to be determined Carbon monoxide and nicotine Formaldehyde and hydrogen cyanide Nitric oxide and nitrogen dioxide Ammonia ~anges of Smoke Constituents On. the basis of reports in the literature, the concentrations for the constituents to be determined fall in the following ranges: -- Constituent Smoke particulate matter - Formaldehyde - Carbon monoxide - Nitrogen dioxide - Nitric Oxide - Hydrogen cyanide - Ammonia - Nicotine - Projected Date of Completion 15 to I000 ug/m3 i0 to 50 ppb I to 50 ppm I0 to i000 ppb I0 to I000 ppb I0 to I000 ppb I to I00 ppb i to I00 ug/m3 We hope to complete the project by the end of October, 1981 Sincerely, Murray Senkus CO: Dr. A. Spears P. Sirridge, Esq.

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