Informs that Fundeberg has been approved by all General Counsel for funding as Council for Tobacco Research Special Project. Refers to previous memorandum for particulars.
Reviews and critiques Soloff's hypothesis regarding smoking and atherosclerosis and points out his past failure to submit progress reports to the Scientific Advisory Board (SAB) for project entitled: "Hemodynamic lipoprotein and enzymatic findings in atherosclerosis and their modification by smoking". Approves "increasing financial support to Doctor Soloff" based on particular conditions, including submission of progress reports and advance review of experimental plans. Includes notes in marginalia.
Transmits reports from various industry and federal sources relative to health effects of smoking. Includes commentary on difficulties in establishing causal inference (attachments missing).
Transmits "reports on the Swedish and American Twin Studies presented in Rome, September 4-7" in view of recent publicity. Indicates no distribution or quotation should be made at author's request in that they have rights of first publication (attachments missing).
Documents for file Spears' various arguments in favor of funding genetics project, noting "it could have significant...benefits relating to statistics; would contribute toward the establishment of filial groups as valuable genetic study entities; and enhance knowledge of general non-tobacco science". Indicates possibility for "full term of ten years".
Refers to shelving of plan to consider "changes in the structure, organization and program of the Council [for Tobacco Research] [CTR]" at upcoming meetings of the CTR and its Executive Committee and discusses particulars under consideration. Includes sections entitled: "Incorporation; Recruiting of Scientific Director; Budget; Direction of Research Effort"; and Attachments A and B (attachments missing).
Transmits attachment and requests comments "on the proposed Hickey [Council for Tobacco Research (CTR)] Special Project". Includes difficult-to-read notes in marginalia (attachment missing).
Discusses reasons for disagreement in industry regarding approval of Hickey's continuation funding as Council for Tobacco Research (CTR) Special Project. Counterbalances Hickey's recent congressional testimony and his scientific reputation with fact that his CTR reports "thus far [are] not earth-shattering nor productive of any immediately valuable use". Suggests Spears and Judge be consulted regarding their views and advocates funding.
Consists of memorandum to file explaining special circumstances regarding providing bridge funding to Hickey for continuation of his Council for Tobacco Research (CTR) Special Project. Indicates problem resulted from Holtzman's failure to handle matters in timely manner.
Summarizes the Industry Council meeting called primarily "to discuss the three preliminary drafts concerning the 'gape' [sic] in knowledge prepared by N.I.H., C.T.R. and A.M.A." Includes other matter discussed, i.e. Dr. Little recommendation for more C.T.R. funding in 1969, S.A.B. additional grants, office space lease, Mason Laboratories publications, and tobacco imports.
Reports support of Theodor Sterling's project. States, "I expressed strong views that we should not go too far in supporting each and every whim of Sterling, lest his credibility and our support of him become suspect." (attachment missing)
Refers to enclosed letter from Dr. Sterling reiterating his recommendation for a complete survey of the cigarette controversy. Suggests passing observations along without comment. Recommends advising Dr. Sterling "that his proposal requires much time and thought and that we should explore it...during the summer." Mentions prior discussion concerning the advisiability of requesting the Hammond data. Invites comment. (attachment missing)
Refers to a recent authorization of more than a $31,852 payment "to Dr. Alvan R. Feinstein in the event he was unable to secure a grant or finanacing from the Public Health Service." Relays Dr. Feinstein's appreciation and advisement of approved government funding.
States, "We are not aware of any toxic effects attributable to Acetate filters." Reports disinterest in eliminating them in the absence of toxicity. Includes notation that reads, "Advised Goldbrenner to write Askin for toxicity info." (handwritten)
Discusses consumer complaint concerning adverse reaction to KENT-III. States that "All flavors and additives used in KENT-III are suitable for use in foods, however this does not preclude the possibility that some rare individual may be allergic to one of them." Denies awareness of any allergic reaction to any of the components. Suggests the possibility that association with the cigarette is "coincidental," but doubts the customer will accept that scenario.
Encloses research proposal from Prof. P. E. S. Palmer for a lung cancer study in a remote area of Southern Rhodesia. Reports that Dr. Palmer outlined the project indicating the results "would be likely to confirm the existence of a high incidence of lung cancer in a population which smokes very little." Discusses funding issues. Includes notation recommending approval. (attachment missing)
Reports events of General Counsel meeting. Contains summaries of seven research projects submitted by the Ad Hoc Committee for approval. Includes investigator, project description, estimated cost, and action. Reports the Committee categorized proposals submitted at an earlier meeting as either A) projects essentially of "adversary" value having a high priority, B) research having a generally defensive character, or C) basic research. Lists all Category A projects with action taken. Reviews reporting of status and funding procedures of projects to General Counsel. Clarifies that "the Ad Hoc Committee is not authorized to make commitment for expenses without previous submission to and approval by General Counsel." Duplicates Bates 87657614.
Reports events of meeting at public relations firm, Hill & Knowlton, "to discuss the proposed statement by the TMSC in England relative to the Royal College of Physicians report due March 7." Relays plans by the TMSC to concede that tobacco is "implicated in the cancer problem." Conveys a primary concern to impress upon the British Tobacco Industry the litigation difficulties facing the American Tobacco Industry. Discusses conference call with TMSC that revealed its plans "to issue a press release challenging the conclusiveness of the Royal College of Physicians report." Indicates critique by scientist, Jeffrey Todd, will not be endorsed by the British Tobacco Industry. Concludes there should be no deleterious effect to the U.S. tobacco litigation, but stresses the importance of improving communication with the British Tobacco Industry.
Questions statistical evidence that indicates "people who smoke cigarettes heavily have a greater tendency to develop cancer of the lung than those who do not smoke cigarettes." States that increased life expectancy partially explains increased lung cancer deaths since "[c]ancer of the lung is essentially a disease of advance years." Discusses several hormone related cancers. Presents additional cancer factors, i.e. constitutional tendency, irritation, and viruses. States that so many factors potentially contribute to the development of lung cancer that it is impossible to determine to what extent each impacts on an individual. Concludes that 60 million people should not be denied smoking on the basis that a portion of the population "have the potentiality of developing cancer when they smoke."
Presents week's research progress. Reports adequate supply of cigarettes were received for distrubution to interviewers. Informs that "opened-up" filter NEWPORT cigarettes are available in the office. Reports events of quarterly meeting of the Scientific Advisory Board of the Council for Tobacco Research and third annual meeting of "our Leaf Division." Finds necessity of "a new product meeting of top management...in order to establish reasonably precise guide-lines for Research...particularly with respect to new filters and/or new flavors."
Responds to likelihood that "the [Standing Scientific Liaison Committee] has developed and submitted a report to Joseph S. Kieth, England's Minister of Health, condemning cigarette smoking and positively reporting the causal connection between tar and nicotine and lung cancer, cardio-vascular disease and emphysema. The report also accepts the theory that cigarette smoking is addictive". Criticizes the British tobacco industry's cooperation with government agencies beginning in 1970 and documents U.S. industry activities and planned responses based on various scenarios. Consists of difficult-to-read document labeled "confidential".
Remarks Mancuso proposal may overlap with the already-approved Sterling project indicating a "lack of coordination on [Council for Tobacco Research (CTR)] Special Projects". Suggests complete review of accomplishments and plans be requested of Selye due to his project's large budget and its status as a continuation request.
Transmits proposals for Council for Tobacco Research (CTR) Special Project funding from Selye and Mancuso. Requests comments to forward to Hardy regarding "our approval or disapproval" (attachments missing).
Chronicles history of nitrosamine reduction in cigarettes and rebuts recent published report by Rhoades and Johnson. Remarks that if their report is confirmed "tobacco could be grown under conditions which would result in smoke not containing dimethyl nitrosamines in the very near future". Notes "filters of all types will reduce [it]". Observes "[c]igarette sales not stand near an all time high, with a curent growth rate of about 3% per annum".