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Bliley Lorillard

[Letter Regarding Dr. William Gutstein's Research Proposal]

Date: 07 Jan 1983
Length: 2 pages
01335653-01335654
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bliley_lor 01335653-01335654

Abstract

Encloses a Dr. Gutstein's research proposal and proposes that his project be approved for $271,015 for two years "as a CTR Special Project." Comments on Dr. Gutstein's research experience, particularly his current animal research dealing "with the relationship between neural stimulation and atherogenesis." Notes his interest in "psychosocial conditions (i.e., stress)" and coronary artery disease. Includes a brief summary of Dr. Gutstein's research hypothesis and a copy "of a recent study conducted by Dr. Gutstein and colleagues that provides some of the experimental background of the present proposal." Requests a response by February 14, 1983." Duplicates Bates 1005064722.

Fields

Type
LETTER
Author (Organization)
Shook, Hardy & Bacon
Author
Sirridge, Patrick M. (Attorney, Shook, Hardy and Bacon)
Recipient
Pepples, Ernest, J.D. (BW General Counsel and Sr. VP)
Stevens, Arthur Joseph (LOR Sr. VP '89-95 and TI Communications)
Served on Lorillard Board of Directors 1985-92, was Senior Vice President from 1989 to 1995, served as General Counsel for Lorillard '93-95. Served on Tobacco Institute Communications Committee.
Witt, Samuel B., III (CTR and RJR Director & Gen. Counsel)
Held various executive positions for RJR and Council for Tobacco Research
Greer, J.H.
Henson, A.
Holtzman, A.
Copied
Brown, J.C.
Jacob, E.J.
Spears, Alexander White, III (LOR President & CEO)
Associated with CTR, used as an expert in the Mississippi case.
Named Person
Gutstein, W.
Named Organization
New York Medical College
Council for Tobacco Research
Region
New York
Keyword
Heart disease
Atherogenesis
Neural stimulation
Coronary artery disease
Research proposals
Psychiatry
Special projects
Thesaurus Term
animal research
stress
pathology
industry sponsored research
research activity
funding

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Page 1: 01335653
LAW OFFICES SHOOK, HARDY & BACON TWENTIETH FLOOR MERCANTILE BANK TOWER I101 WALNUT KANSAS CITY, MISSOURI ~,410~, (816) 474-6550 JAt~ 1 I 1983. January 7, 1983 Joseph Greer, Esq. Arnold Henson, Esq. Alexander Holtzman, Esq. Ernest Pepples, Esq. Arthur J. Stevens, Esq. S. B. Witt III, Esq. Gentlemen: The enclosed research proposal from Dr. William Gutstein ~edical College requests support in the amount of two years. We recommend that the proposal be approved a CTR Special Project. Dr. Gutstein is Professor of Pathology and Psychiatry at New York Medical College in Valhalla, New York. He is an experienced investigator and has published extensively in the heart disease field. Most of his recent animal research has dealt with the ~ relationship between neural stimulation and atherogenesis. Dr. ~ Gutstein hypothesizes that responses to psychosocial conditions ~ (i.e., stress) lead eventually to coronary artery disease in ~ susceptible individuals. A succinct summary of Dr. Gutstein's ~ research hypothesis can be found on page 1 (Abstract) of the ~ proposal. Also attached is a copy of a recent study conducted by Dr. Gutstein and colleagues that provides some of the experimental background of the present proposal. It is our view that Dr. Gutstein and his colleagues have developed an important project to study objectively the question of whether stress and other psychosocial conditions are causally related to the occurrence of coronary artery disease. As a research pathologist who also holds a professional appointment in psychiatry, Dr. Gutstein seems particularly well qualified to perform the research.
Page 2: 01335654
SHOOK, HARDY ~, BACON January 7, 1983 Page Two We have discussed the proposal with Dr. Som~ers who believes that it represents interesting work and is worthy of support. Accordingly, we recommend that the proposal submitted by Dr. Gutstein be approved for two years as a CTR Special Project. If possible, we would like to have your response by February 14, 1983. Sincerely, Patrick M. Sirridge PMS:sh Enc. cc & enc: Ms. Janet C. Brown Edwin J. Jacob, Esq. bcc & enc: Dr. A. W. Spears

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