Bliley Lorillard
[Regarding Recent CTR Actitivies]
Abstract
Responds to seven points raised in February 9 letter regarding various Council for Tobacco Research (CTR) and international projects and initiatives, including several animal chronic inhalation studies and "trial relationship" with "David Lawrence, the science writer".
Fields
- Company
- Council for Tobacco Research
- Type
- LETTER
- Author
- Hockett, Robert Casad, Ph.D. (CTR Scientific Director)Scientific Director of the Council for Tobacco Research from 1972-1974 (WSJ 2/11/93; Allman complaint). Bio-Research Institute BRI conducted a study for the CTR. When Syrian hamsters were exposed to smoke twice a day for 59 to 80 weeks, 40% of those of a cancer-susceptible strain and 4% of a resistant strain developed malignant tumors (WSJ 2/11/93). Before publishing the study in 1974, BRI's founder, Frederic Homberger, sent a manuscript to Robert Hockett, then scientific director of the CTR. Dr. Homberger says he had to do so because halfway through his study, the CTR had changed it from a grant to a contract so they could control publication. They were quite open about that (WSJ 2/11/94. Soon thereafter, Hockett and CTR lawyer Edwin Jacob went to Dr. Homburger's summer house in Maine. Hockett and Jacob did not want BRI to call anything cancer, they wanted it to be "pseudo-epitheliomatous hyperplasis," a euphemism for lesions preceding cancer (WSJ 2/11/93). Dr. Homberger said no, this is not right, it is cancer. Jacob told Dr. Homberger that BRI would never get a penny more if the paper was published without the changes. At the last minute, Dr. Homberger changed the final proofs to read "microinvasive" cancer, a microscopic malignancy. Nevertheless, BRI was never funded by the CTR again (WSJ 2/11/96) Hochett made a statement, as scientific director of the CTR circa February 1972 that neither tobacco and health research in general, nor that of the Council for Tobacco Research has established that tobacco use or cigarette smoking in particular is a major health hazard (Allman complaint, pp. 41-42). Robert C. Hockett was Scientific Director, Vice President and Research Director of CTR. See Bio-Research Institute, TTLA Almanac - Names. (N.M.'s CTR Who's Who)
- Author (Organization)
- *Council for Tobacco Research-- U.S.A. Inc. CTR (Formerly Tobacco Industry Research Committee (TIRC))Created and funded by the tobacco industry to award grants to study of the link between smoking and disease. Part of a four decade effort to cast doubt on the links between smoking and disease.
- Recipient
- Yeaman, Addison Y. (BW VP & General counsel; CTR Chairman of Board)General counsel for B&W. CTR Chairman/President 1975-1981
Subsidiary of BAT U.S., located in Louisville, KY.
Key legal strategist in many capacities, including Jacob, Medinger & Finnegan (CTR). Career stems from 1950's. CTR Special Projects.
Key legal strategist in many capacities, including Jacob, Medinger & Finnegan (CTR). Career stems from 1950's. CTR Special Projects.
Defense
Defense
Vincent Lisanti was a CTR Associate Research Director. (PMI's Introduction to Privilege Log and Glossary of Names, Estate of Burl Butler v. PMI, et al, April 19, 1996) Dr. Vincent F. Lisanti is a former Associate Research Director of CTR. (CTR Initial Disclosure)
Evaluated smoking machines for animal inhalation studies and did toxicity tests on rodents.
Document Images
~'--- ..... memoranda to the Scientific Advisory Board
~h~._- both Leuche~enberger and ~v%ri be put on
su~esting ~ +
min~al month-to-month pro rata support to maintain st~'f ~n~
keep present programs going,- ~nt~l such t~ as plans cm% be
shaped up to include the best machine de~ices, check-out of-
~als for l=~ virus infections~ ~gree~nt on " ~ ~
methods ~ l~g fixation, sectioning, stai~, ex~dnatlon~
Copies of %he Battelle Institute repot ~e being processed
%his office for trmnsmittai %o you for review bM general co~sel~
%~ethe~ %~th a c~pM of ~ letter to ~. ~ir suggesting the
series of observations needed to ro~ out this prel~in~y work
~d h~ocking out ~eas in which new eontinueti~ studies might
be appropriate. .
! ~ve a reservation to H~b.~g for tomorrow e~nlng, Febzu~y 13,
and appointments both there ~d %ith ~. Harris ~d Negroni,
the ~C Teci~nic~l and Scientific Co~.zi~tee end with ~. De~id
Kissen. (I have sen~ you his comprehensive progress report which
contains an InquirM concerning f,,mther s,~port beMond the
~e~ p~riod. )
~ Lisanti has s~nt all the past --'-
• ~ca at Mason Rese~ch ~nstltute
loo~ng into t~ status of the machines end the te~s on these~
getting abreast of resets in the n~.erous prei~minery~ ~eas
studies on biochemical and other monitori~ tests that might be
used in c~onic st'~ies, ~d working out a broad sc~e project
plan for discussion %dth the Scientific Advisory Bo~d on M~ch
Februsry ~, i .e68
Te~,~n.c~z Committee shou~ ~cheduled This should be done
- show whether a ~ge-generel conference with the British snd
uer .... n~ .~ before we settle on a design
~ Dr. Little phoned me to inquire ,4h~the~ the ~eneral co~ns~! ~ou~ h~.d ~pproved
~Dur ~oin~ ~ne~d with a tr~ai rei;~tion with David La~Tence~ the science ~ite~,-
.... ~;, ..... per ann,Am Since he is very keen sbout It 8rid will
.... o.~ ~-~e status of--~hiz plan? ~ fav~
i~. as
Edwin Jacob, Esq~
