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1996-1997 Research Agenda - Request for Applications

Date: No date
Length: 36 pages
800105375-800106143
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Named Organization
World Health Organization
University of Minnesota
University of Lisbon
NYU Medical Center
Concordia University
University of Vermont
Colorado State University
University of Pittsburgh
University of Gothenburg
San Diego State University
University of Missouri-Rolla
University of Tulsa
Wake Forest University
University of Toledo
Tufts University
US Public Health Service
National Institute of Standards and Technology
Virginia Commonwealth University
US FDA
University of Washington
University of Illinois
Philip Morris USA
Brown & Williamson Tobacco Corporation
Japan Tobacco Incorporated
US EPA
Meharry Medical College
Oak Ridge National Laboratory
US Department of Energy
TRC Environmental Corporation
Washington University
Campbell University
Danish National Institute of Occupational Health
Penn State University
Science Advisory Board
Svenska Tobaks AB
Ecusta
Texas A&M University
Meckler Engineers Group
University of Arkansas for Medical Sciences
University of Aarhus
Proctor & Gamble
Ford Motor Company
Virginia Polytechnic Institute
NIEHS
Standard Commercial Corporation
Shorewood Packaging
Pennsylvania State University, The
University of Mysore
University of Tennessee, The
DIMON International
Cornell University Medical Centre
New York University Medical Centre
Ottawa
Mead Paper
Mundet International Limited
Quest International Flavors USA
Somerville Packaging Corporation
United Technologies Carrier Corporation
Gas Research Institute
Touro College
United Technologies Research Centre
ITRI
University of Alaska Fairbanks
Dorgan Associates
NYU Medical Centre
ICF Kaiser Engineers Incorporated
National Medical Advisory Service Incorporated
University of North Arizona
Synesthetics Incorporated
Apex Environmental Incorporated
Tulane University Medical Centre
Rexair Incorporated
Battelle
St Louis University
Building Science Corporation
IRC Canada
University of Denvar
Johnston Controls Incorporated
National Centre for Occupational Health South Africa
Prairie Swine Centre Incorporated
Health Effects Institute, The
University of Kentucky
University of California
University of Texas
University of Reading
Southern Illinois University
RJ Reynolds Tobacco GmbH
University of Maryland
Johns Hopkins School of Hygiene and Public Health
Illinois Institute of Technology
Brookhaven National Laboratory
Virginia Polytechnic Institute and State University
Universal Corporation
Lorillard Corporation
Utah State University
American Health Foundation
Harvard School of Public Health
University of Wisconsin Hospital
Ohio State University
University of Maryland School of Medicine
Boston University School of Public Health
Jacksonville University
National Institute of Health Guidelines Committee
Northeastern University
University of North Carolina
Named Person
Lebowitz, Michael D
Woods, James E
Levetin, Estelle
Eisenberg, Max
Kessler, Irving
Matanoski, Genevieve M
Utell, Mark J
Wolf, Alfred P
Adams, Eric W
Arora, Sanjay
Aust, Steven D
Bascom, Rebecca
Bell, Iris R
Benjaminson, MA
Billick, Irwin H
Blumenthal, Malcolm N
Brennan, Terry
Burleson, Gary R
Burrell, Robert
Cheek, Jeffrey
Chen, Qingyan
Croome, Derek J
Crouse, William E
Cain, William S
Das, Salil K
Delumyea, R Del
Dorgan, Charles
Dowell, Russell T
Driscoll, Kevin
Dunn, Bonnie
Evans, Hugh L
Fales, Henry M
Frampton, Mark W
Larson, Susan M
Francis, Bettina M
Gardner, Donald
Last, Jerold A
Gearhart, Jeffrey
Getchell, Thomas V
Giardino, Nicholas J
Giese, Roger
Gilbert, Stephen L
Hedge, Alan
Lehrer, Samuel B
Glicksman, Leon R
Ford, Timothy
Jenkins, Roger A
Gong, Henry
Meckler, Milton
Gordon, Terry
Greene, Robert
Haghighat, Fariborz
Hajjar, David
Hasselblad, Victor
Hemenway, David
Reif, John
Roboz, John
Rogers, John M
Sen, Mihir
Sharma, Vinod Kumar
Silver, Wayne
Smith, Douglas A
Stoner, Gary D
Stuart, Bruce
Temple, Robert W
Turner, Simon
Tyler, Walter S
Ultman, James
Wallace, Lance
Wispe, John
Yager, James
Yang, Chin S
Zhang, Yuanhui
Guerin, Michael R
Lewis, Roger
Lippman, Morton
Witschi, Hanspeter
Kilpatrick, James
Akland, Gerald
Burge, Harriet
Bush, Robert
Djordjevic, Mirjana
Dockery, Douglas W
Doty, Richard L
Hoidal, John R
Johnting, Jennifer
Kanarek, Marty S
Kleeberger, Steven R
Kleinman, Michael T
Knutson, Earl
Kuhlman, Michael R
Lewis, Robert
Loyalka, Sudarshan K
McGrath, James J
Mennear, John H
Nielson, Gunnar
Ogden, Michael
Otto, David
Rohde, Charles
Spannhake, E William
Valberg, Peter
Moschandreas, Demetrios
Arey, Janet
Hoffman, Dietrich
Bohanon, Hoy
Nagda, Niren L
Brunnemann, Klaus
Kilpatrick, S James
Camboni, Silvana
Klinger, Lorry A
Menzel, Daniel
Palmer, Kenneth C
Potter, William T
Ramsey, J Michael
Stedman, Donald H
Benson, Janet
Baker, AJ
Castagnoli, Neal
Costa, Daniel L
Rood, Mark J
Lacey, John
Leith, David
Bement, Collette L
Boyse, William K
Christianson, Leslie L
Cosma, Greg
Costa, Lucio G
Cunningham, Jennifer B
Dharamsi, Amin
Duffy, Lawrence K
Eastmond, David A
Fang, Jin Bao
Gatley, John
Gilbert, Avery Nelson
Gilmour, Matthew Ian
Gornes, Joao FP
Goud, S Niranjan
Graham, Charles W
Grinsh, Sergey A
Hittle, Doug C
Holbrook, G Thomas
Horner, W Elliott
Hung, Ling-Ling
Inyang, Hilary I
Keller, John G
Kjaergaard, Soren
Koch, Wendy H
Lehnert, Bruce
Linn, Bill
Lorig, Tyler S
Madhusudhan, B
Koller, Loren
Koutrakis, Petros
Nishimoto, Marc
O'Callaghan, Michael W
O'Neil, Carol
Otten, James
Ritter, Gary L
Saman, Namir
Samini, Behzad S
Ryan, Lisa
Smith, Raymond A
Sauer, Hary J
Sawnor, Marcia
Solornon, Jerome J
Swift, David L
van Berkel, Gary
Yousefi, Vali
Zannetti, Paolo
Zelikoff, Judiath T
Notes

Author name is not available in the document Missing originals: 800105409-800106141. Handwritten.

UCSF Code
hle51a99
Type
agenda
table
Region
United Kingdom
China
Sweden
Canada
South Africa
Date Loaded
01 Dec 2004
Box
0161
Folder
bcmn0000

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prevalent being eye, nose, and throat irritation. While considerable progress has been made in the development of technology to measure contaminant concentrations, greater effort is needed in quantifying human responses to indoor air environments. Studies to date have shown that worker health in office buildings, for example, is influenced by individual, perceptual, psychosocial, and psychophysical factors. CIAR requests applications for research to: • Elucidate the relationship among disorders expressed by occupants in buildings and the importance of perception. Determine the baseline rates of symptom reporting under various, well-documented circum- stances. This research would most likely involve the development of improved sampling strategies fog surveying building occupants and improved serf-reporting measures, interview techniques, and o~her approaches to assess occupants' health problems. • Develop convenient, objective ways, based on physiological or biochemical measurements, to assess irritation and to validate symptoms of irrita- tion. Improve the sensitivity of existing indices of eye, throat, and nasal irritation. • Explore the basis for individual and group differences in perceptual sensitivity and annoyance to indoor contaminants. Relevant factors could include age, sex, and personal history of smoking behavior, allergy, and respiratory infection. • Develop and validate a predictive human structure-activity model for irritants. Explore the potential for extrapolating the existing structure- activity data for irritants in animals to humans. • Develop convenient, objective ways based on objective measurements, to assess the impomance of pollutant per- ception on alterations in performance. Engineering Control of IAQ The decrease of indoor contaminants most probably will lead to reduction of adverse health effects. The choice of an engineering control strategy depends strongly on the psychosocial and psychophysical influences described above as well as the measurable environmental contaminant concentrations. Therefore, develop- ment of "healthy building characteris- tics" involves knowledge of both the physical environment and occupant responses. Applications are requested for:. • Developing engineering strategies to control either indoor comfort para- meters or indoor air quality parame- ters, or both. Strategies that enhance the welfare of occupants (comfort parameters) and their health (indoor air parameters) are preferred to controls that address just one or the other. • Developing engineering control strategies to reduce occupant expo- sures to indoor air contaminants in office buildings and in residences. Develop protocols to assess the efficiency of each proposed strategy. • Developing criteria and standards for the design of spaces to be occupied and for design of control systems, to minimize or mitigate indoor air quality problems. O'! BATCo US DOJ v Philip Morris
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Application Process LETTER OF INTENT: CIAR requests submission of a two to three page letter of intent, including a synopsis of the proposed research with reference to the project's specific goal(s), the general approach to be used, identification of all participating institutions and an estimate of the total monies that will be requested. These letters will be used to plan the proposal review process. The letter of intent is not binding on CIAR or the applicant. This letter should be -eceived no later than thirty (30) days prior to the deadline for submitting applications, at the following address: Center for Indoor Air Research 1099 Winterson Road, Suite 280 Linthicum, Maryland 21090 CIAR will notify the applicant ifa full application is not warranted. FORMAT: Applications must be submitted on the attached "Application for CIAR Research Contract". Investigators should review the Application for CIAR Research Contract General Information and Instructions found on pages 12 to 14. Inquiries regarding application procedures and review procedures may be directed to the Center at the above address or by calling (410) 684- 3777. If two appli- cations are interdependent or closely related, they should be appropriately cross-referenced in the project plan. Two copies of the abstract and twelve (original and eleven) copies of the application (including abstracO are needed by CIAR for the review process. Each copy of the application, except the original, should be bound wilh a label containing the title of the proposal and the principal investi- gator's name. DEADLINES: Applications must be postmarked by June 1. Proposals not meeting this deadline will be held for the next funding cycle. Management of Research Contracts Research Agreements The Center for Indoor Air Research awards contracts, renewable annually for the number of years approved by the Board of Directors if work is progressing satisfactorily. The Research Contract has been designed to maximize the integrity of the scien- tific process while providing needed protections and meeting applicable regulations. Proposals and any addenda or modifications will be appended and made part of the contract. Progress Reports Investigators are required to submit progress reports at five months and ten months of each contract year, except for the last year of the project, when the final report is substituted for the usual ten-month report. These reports are reviewed by the project monitor. The basic objective of the five month report is to indicate how much progress has been made in the devel- opment of experimental procedures, which objectives have been completed, and what problems, if any, have arisen. t~ 135 BATCo US DOJ v Philip Morris
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The ten-month report is actually a combined progress report and renewal application for the next year's funding. CIAR's decision regarding renewal of the contract is based upon the informa- tion provided by the investigator in this repo~ The ten-month report should provide a detailed account of experimental results obtained during the funding period, as well as a discus- sion of specific objectives for the coming year and a budget. Site Visits CIAR staff (project monitor) usually conducts site visits to the laboratories of its funded investigators during the project period. The purpose of these visits is to evaluate the status of the project, and to provide an opportunity for an exchange of ideas between the investigator and CIAR scientists. Final Report As part of the research project, the investigator prepares a final report which describes the study and its findings. The investigator's draft final report is reviewed by the project monitor. Some reports are reviewed also by peers who represent a broad range of relevant experience. The objective of the CIAR review process is to ensure that the Investigator's Report is complete, precise, and understandable. Review comments may be sent to the investigator who then has an opportunity to respond to the comments and, if necessary, to revise the report. Guidelines for the preparation of final reports to CIAR appear in Appendix C. Publications It is the policy of the Center to strongly encourage investigators to publish results of research conducted with CIAR funds in the open scientific literature. The following statement, acknowledging CIAR support, should appear in all publications resulting from work funded by CIAR: "Research described in this article was supported (in part) by the Center for Indoor Air Research." Original reprints of all journal articles, copies of abstracts, and review articles describing CIAR-funded research should be sent to the Center. Contract Administration Policy Payments will be made quarterly to the institution where the research is being conducted. A payment schedule other than quarterly must be requested and approved by the Center prior to commencement of a contract. Payments are made upon receipt of an invoice from the institution. It is the Center's policy to permit quarterly billing of 22.5% of the total contract less equipment. Ten percent of the total contract amount is with- held pending receipt and acceptance of the ten-month/final report by the Center. Equipment should be invoiced in the quarter in which it is purchased. Contracts may not be transferred from one institution to another due to a change in affiliation by principal investigator without express permis- sion of the Center. C~ O'1 BATCo US DOJ v Philip Morris
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A Contract may be terminated prior to normal expiration date by the contrac- tor upon notification to the Center with a statement of reasons for termination. Unexpended funds shall be returned to the Center for Indoor Air Research either upon expiration or termination of the project. Budgets are presumed accurate at the time of award; however, up to 20% of the funds may be reapportioned among all categories, except for travel, without prior approval. If, for any unforseen reasons, additional funds or reapportionments exceeding 20% are required, such requests will be consid- ered by the Center upon receipt of a complete statement of reasons for such change. PLEASE NOTE: If funds are reapportioned into category (g), equipment, and/or category(f), sub-contracts, subsequent reduction in category (i), indirect costs, will result and, thus, reduction in the total project award. Application for CIAR Research Contract General Information and Instructions Submission of Applications Complete applications received by the June 1 st postmark deadline will be reviewed. Funding of awarded projects will begin the following January Ist. Submit the original and eleven addi- tional copies. If photographs are included, send one original set. Submit two additional copies of the Research Abstract form. Append as much material as required. Type, single space, using 8 1/2" x 11" paper and label each sheet with the name of the Principal Investigator in the upper right hand comer. Number each page consecutively beginning with page 4. DO NOT insert pages between form pages FI and F3. Investigators will receive written acknowledgement of receipt of the application. Research Plan 8. Aims State the objectives of the research and the hypotheses you will test. 9. Significance of Proposed Work Identify gaps in the research area and discuss pertinent background material that supports the impor- tance of the work. 10. Preliminary Studies Critically evaluate existing knowl- edge pertinent to the application with reference to the key litera- ture. Provide an account of the principal investigator/program director's preliminary studies pertinent to the application and/or any other information that will help to establish the experience and competence of the investigator to pursue the proposed project. 11. Experimental Design and Methods Outline the experimental design and the procedures to be used to accomplish the specific aims of the project. Include the means by O0 0 0 BATCo US DOJ v Philip Morris
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which the data will be collected, analyzed, and interpreted. Include a description of the statistical methods to be used for analysis and interpretation of the data. Describe the proposed statistical procedures with sufficient detail to allow evaluation by a biostadstical reviewer. Describe any new methodology and its advantage over existing methodologies. Discuss the potential difficulties and limitations of the proposed procedures and alternative approaches to achieve the aims. Provide a tentative sequence or timetable for the investigation (i.e., a columnar or graphical represen- tation of your schedule for comple- tion of tasks). Point out any proce- dures, situations, or materials that may be hazardous to personnel and the precautions to be exercised. Provide a list of literature you cited in your application~ 12. Other Support List all currently active and pend- ing support for all key personnel involved in this proposal. Include the source of support, percentage of appointment, dates of project period, a brief description of the project and whether it overlaps, duplicates, replaces, or supplements this proposed work in any way. 13. Budget Cost Data: Provide sufficient detail and analysis to assure the Center that the proposed costs are reasonable and that adequate accounting procedures will be used. CIAR has no specific limita- tion on the budgets of research proposals. Most contracts are expected to be in the range of $50,000 to $200,000 per year, including overhead. Projects requiring larger budgets must have exceptional promise for developing important methods or information for understanding indoor air quality. Personnel: List the names and positions of all applicant organiza- tion personnel involved in the project for which salaries are requested. Note those which are considered essential to the project. Estimate the percentage of time or effort on the project for profes- sional personnel and non-profes- sional personnel. List the dollar amounts separately for each indi- vidual for salary and fringe bene- fits. Fringe benefits may be requested to the extertt that they are treated consistendy by the applying organization as a direct cost to all sponsors. Consultant Costs: Consultant service should be explained by indicating the specific area in which such service is to be used. Identify the contemplated consul- tants. State the number of days of such services estimated to be required and the consultant's quomd rate per day. Equipment: If special-purpose equipment is being proposed, provide a description of the item(s) and details of the proposed cost. If fabrication by the applicant is contemplated, include details of material, labor, and overhead. Alterations and Renovations: If the costs of essential alterations of facilities, including repairs, paint- ing, removal or installation of par- titions, shielding, or air condition- ing, are requested, itemize them by category and justify them fully. BATCo US DOJ v Philip Morris
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Supplies and Other Expenses: All supplies and other expenses should be itemized in sufficient detail to allow reviewers to understand the major categories of expenditures (i.e., animals, glassware, media chemicals, as well as publication costs, page charges, and books, listed by category and unit cost). Itemize and justify such items as patient travel and per diem costs, rentals, leases, and computer costs. Unusually expensive items for spe- cial processes should be separately identified by quantity and price and the use or application thoroughly explained in the project plan. Each individual expense item must be categorized as supplies or other expenses according to the practices of the accounting office of your institution. Travel Expenses: Indicate the esti- mated number of trips required, destination, reason for travel, and cost. Identify and support any other special transportation costs attributable to the performance of this project. CIAR ?ays for foreign travel only if it is approved in advance of the trip. Subcontracts: Itemize and enter a total for these costs. Describe and justify all appropriate costs for ser- vices purchased for, or associated with, third parties. Indirect Costs: Indirect costs are limited to a maximum of 25 percent of budget items, excluding sub-contracts and equipment on which no indirect costs are payable. Human Subjects: The Center requires that Institutional Review Board approval for any procedures involving human subjects must be submitted with the application. Laboratory Animals: The Center endorses the NIH policies on the care and use of laboratory animals, and requires that any proposed experiment involving the use of experimental animals be approved by the Institutional Animal Care and Use Committee at the investigator's institution. Documentation of approval by the local animal care committee will be required. Research Abstract: A concise, descriptive summary of the project must be submitted with the appli- cation. A form is provided for this purpose. Completeness to Applications: Provide all information requested. The signature and typed names of the institutional officer and princi- pal investigator must be on the application. Notification After Review of Application: Investigators will be notified, in writing, of the decision on their proposal. Mailing Instructions: Include eleven copies and an original of each and every part of the applica- tion, plus two additional copies of the Research Abstract form. NOTE: Each of the eleven copies must be placed in a binder with a label containing the title of the application and the name of the principal investigator. Mail the application to: Center for Indoor Air Research 1099 Winterson Road, Suite 280 Linthicum, Maryland 2 i 090 BATCo US DOJ v Philip Morris
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Appendix A CIAR Membership CHARTER MEMBERS Philip Morris U.S.A. R.J. Reynolds Tobacco Company Lorillard Corporation Svenska Tobaks AB Brown & Williamson Tobacco Corporation REGULAR MEMBERS Hoechst Celanese Mead Paper Japan Tobacco Inc. ASSOCIATE MEMBERS Ecusta, Division of PH Glatfelter DIMON International Mundet International Ltd. Quest Intemalional Flavors, USA Shorewood Packaging Somerville Packaging Corp. Standard Commercial Corp. United Technologies Carrier Corp. Universal Corporation C~ /3ATCo US DOJ v Philip Morris
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BLANK SHEET BATCo US DOJ v Philip Morris
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Appendix B CIAR Peer Reviewers Eric W. Adams United Technologies Research Center Gerald Akland U.S. EPA Janet Arey University of California, Riverside San jay Ar0ra Virginia Polytechnic Institute Sleven D. Aust Utah State University A. J. Baker The University of Tennessee Rebecca Bascom University of Maryland Bryan R. Becker University of Missouri-Kansas City Iris R. Bell University of Arizona Collette L Bement TRC Environmental Corporation M. A. Benjaminson Touro College Janet Benson Lovelace ITRI Irwin H. Billick Gas Research Institute Malcolm N. Blumenthal University of Minnesota William K. Boyes U.S. EPA Hoy Bohanon R. J. Reynolds Tobacco Co. Terry Brennan Camroden Associates Klaus Brunnemann American Health Foundation Harriet Burge Hma,ard School of Public Health Gary R. Burleson U.S. EPA Robert Burrell West Virginia University Medical Center Robert Bush University of Wisconsin Hospital Silvana Camboni Ohio State Universi~ Neal Castagnoli, Jr. Virginia Polytechnic Institute Jeffrey Cheek University of California-Davis Bean T. Chen ITRI Qingyan Chen M.I.T. Department of Architecture Leslie L. Christianson University of lllinois-Urhana-Champaign Theodore Colton Boston University School of Public ttealth Emanuela Corsini NIEHS O BATCo US DOJ v Philip Morris

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