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AHF NCI Collection

Tsna in Ms of Overcased Mlk

Date: 14 Nov 1988
Length: 3 pages
2501310601-2501310603
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Fields

Type
MEMO, MEMORANDUM
CHAR, CHART, GRAPH, TABLE, MAPS
SCRT, REPORT, SCIENTIFIC
Named Organization
Inbifo, Institut Fur Biologische Forschung
Characteristic
MARG, MARGINALIA
Brand
001p
002p
003p
Team
nitrosamines
Author
Speck, M.
Recipient
Fink, W.

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Page 1: qxk32e00
F.T.R. RESEARCH AND DEVELOPMENT CH - 2003 NEUCHATEL / SWITZERLAND INTER - OFFICE CORRESPONDENCE To: W. Fink Date: November 14, 1988 From: ~~pecls~/sid Doc name: 1188spm57 Subject: TSNA in MS of overcased MLK TSNA's were determined in MS of regular MLK and MLK with 10% or 20% BU overcasing since it was assumed that BU casing and treatment could influence the TSNA delivery. The cigarettes were produced in the context of the Process Development project ROUGE and had following amounts of BU casing: Prototype BU casing 002P regular 001P 10% overcasing 003P 25% overcasing Analytical results of these cigarettes delivered by the Smoking lab are shown in Tab. 1. No differences can be seen in the values from one cigarette to the other. MS-TSNA values are shown in Tab. 2. No clear difference can be seen between the TSNA's of the regular MLK and the overcased. A tendency to higher values with overcasing might be seen expressed by the increase of TSNA's from 002P to 003P. The TA's of the three cigarettes, however, show the same pattern as the TSNA's and the differences in the TSNA values can probably be explained through this. These results indicate that TSNA's in MS are not influenced by BU casing. Regards. Enclosures
Page 2: qxk32e00
- 2 - Table 1 : Project ROUGE - Analytical results Prototype Blend code Casing 002P ML022 regular 001P ML022 + 10% 003P ML022 + 20% Total alkaloids % 1.66 1.58 1.78 Nitrate-nitrogen % 0.19 0.20 0.20 Reducing sugars % 9.2 8.5 7.6 Total weight mg/cig 983 978 978 Tobacco weight at 12.5% OV mg/cig 759 753 751 Cigarette RTD mm/wg 109 105 106 Dilution % 16 15 15 Firmness at 12.5% OV mm 3.17 3.21 3.10 Tar mg/cig 16.0 16.4 16.0 SN mg/cig 1.06 1.09 1.07 CO mg/cig 16.1 16.1 16.1 NO mg/cig 0.22 0.22 0.22 Puff count 8.9 8.9 9.0
Page 3: qxk32e00
3 Table 2 : MS-TSNA's of regular and overcased MLK Prototype Casing TSNA (ng/cig) (a) ( g) NNN NAB / NAT NNK 002P regular 197 190 95 001P + 10 184 199 89 003P + 25 228 211 101 (a) TSNA determined at INBIFO; the values for NNN and NAB/NAT are too high when compared to the values previously found for 002P.

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