AHF NCI Collection
Histopathology of Syrian Golden Hamsters After S.C. Administration of 1 Mmol Nnk and Nnn
Abstract
#97 Results of dosages of NNK and NNN given to hamsters.
Fields
- Keyword
- nitrosamines
- NNK
- NNN
- Location
- cd 4
- Team
- nitrosamines
Document Images
0
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REFERENCE 7
~~. .
Environmental Carcinoq nesis
(FOR INTERNAL USE ONLY1
TABLE 1.
HISTOPATHOLOGY OF SYRIAN GOLDEN HAMSTERS AFTER S.C.
ADMINISTRATION OF 1 PTMOL NNK AND NNN.
No. of Animals NNK
lOd 10° NNN
9a 9s
Nasal Cavity 6 5 0 0
',`Tracheal Papillomas 3 4 1 0
Lung Adenomas . 4. 2 0 0
Lung Carcinomqs 6 4 1 0
Kidney Pietastases* 1 0 0 0
Adrenal Cortical Tumors** 0 1 0 0
`Colon Adenomas or
Hyperplastic Mucosa
0 1
1
0
Uterus, Adenocarcinoma 0 0 0 0
Und.i=ferentizted Carcino-
rr~a in Pancreatic Area
1. 0
0
Anaplastic Carcinomas of
Unknown Origin
0 0
.0
0
Soft tissue Sarcomas (.legk
0 0 ., l
0
0
r
* S 11 -( b-b' f 1 )
s
o
*x
a~,
q
~ ~y rom ung
ous ce carcino;n~ pr
Undifferentiated, benign or'borderlirie.
,otal dose NNK - 188 mg, given over 25 weeks (75 appli cations)
=o:a1 dose NNN - 160 mg, given over 25 weeks (75 applications)
~~YNTIAL
Untreated
3e
0
0
1
0
0
